IL146190A0 - Dermal anesthetic agents - Google Patents

Dermal anesthetic agents

Info

Publication number
IL146190A0
IL146190A0 IL14619000A IL14619000A IL146190A0 IL 146190 A0 IL146190 A0 IL 146190A0 IL 14619000 A IL14619000 A IL 14619000A IL 14619000 A IL14619000 A IL 14619000A IL 146190 A0 IL146190 A0 IL 146190A0
Authority
IL
Israel
Prior art keywords
compounds
anesthetic agents
dermal
aminoindane
dermal anesthetic
Prior art date
Application number
IL14619000A
Other languages
English (en)
Original Assignee
Bridge Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bridge Pharma Inc filed Critical Bridge Pharma Inc
Publication of IL146190A0 publication Critical patent/IL146190A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14619000A 1999-06-10 2000-06-06 Dermal anesthetic agents IL146190A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13835399P 1999-06-10 1999-06-10
US17926700P 2000-01-31 2000-01-31
PCT/US2000/015490 WO2000076510A1 (en) 1999-06-10 2000-06-06 Dermal anesthetic agents

Publications (1)

Publication Number Publication Date
IL146190A0 true IL146190A0 (en) 2002-07-25

Family

ID=26836123

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14619000A IL146190A0 (en) 1999-06-10 2000-06-06 Dermal anesthetic agents
IL146190A IL146190A (en) 1999-06-10 2001-10-25 Dermal anesthetic agents

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL146190A IL146190A (en) 1999-06-10 2001-10-25 Dermal anesthetic agents

Country Status (18)

Country Link
US (1) US6413987B1 (pt)
EP (1) EP1185267B1 (pt)
JP (1) JP2003501469A (pt)
CN (1) CN1355700A (pt)
AT (1) ATE335482T1 (pt)
AU (1) AU777517B2 (pt)
BR (1) BR0011028A (pt)
CA (1) CA2376819C (pt)
CY (1) CY1105721T1 (pt)
DE (1) DE60029954T2 (pt)
DK (1) DK1185267T3 (pt)
ES (1) ES2267546T3 (pt)
IL (2) IL146190A0 (pt)
MX (1) MXPA01012632A (pt)
NO (1) NO323856B1 (pt)
NZ (1) NZ515143A (pt)
PT (1) PT1185267E (pt)
WO (1) WO2000076510A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60122541T2 (de) * 2001-12-21 2007-09-13 Chiesi Farmaceutici S.P.A. 2-Indanylaminoderivate zur Therapie von chronischen, akuten oder entzündlichen Schmerzen
EP1566378B1 (en) * 2002-11-26 2012-08-15 Maruishi Pharmaceutical Co., Ltd. Isoindoline derivative
US7718674B2 (en) * 2004-09-27 2010-05-18 Bridge Pharma, Inc. Methods of relieving neuropathic pain with the S-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine
US20060079558A1 (en) * 2004-09-27 2006-04-13 Bridge Pharma. Inc. R-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine and other dermal anesthetics
US20110218218A1 (en) * 2005-09-23 2011-09-08 Bridge Pharma, Inc. Formulations Of Indanylamines And The Use Thereof As Local Anesthetics And As Medication For Chronic Pain
WO2007038325A2 (en) * 2005-09-23 2007-04-05 Bridge Pharma, Inc. Indanylamines and their use for local anesthesia and chronic pain
US7592458B2 (en) 2006-07-21 2009-09-22 Wright George E Dermal anesthetic compounds and pharmaceutical compositions for inducing local anesthesia and mitigating neuropathic pain
DK2244737T3 (da) 2008-01-22 2019-07-08 Univ Texas Flygtige anæstetiske sammensætninger omfattende ekstraktionsopløsningsmidler til regional anæstesi og/eller smertelindring
JP6184328B2 (ja) * 2011-02-18 2017-08-23 アサナ・バイオサイエンシズ，リミテッド・ライアビリティ・カンパニー アミノインダン化合物および疼痛治療におけるその使用
US8809372B2 (en) 2011-09-30 2014-08-19 Asana Biosciences, Llc Pyridine derivatives
EP2771320B1 (en) 2011-10-24 2016-06-22 Endo Pharmaceuticals Inc. Cyclohexylamines
WO2014028675A1 (en) * 2012-08-15 2014-02-20 Endo Pharmaceuticals Inc. Use of aminoindane compounds in treating overactive bladder and interstitial cystitis
DK3380080T3 (da) 2015-11-23 2021-12-13 Nortic Holdings Inc Topikal filmdannende spray
KR20210106503A (ko) 2018-12-19 2021-08-30 노틱 홀딩스 잉크. 비강내 리도카인의 치료 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923813A (en) 1969-12-19 1975-12-02 Christiaens Sa A Derivatives of 2-aminoindanes
BE760018A (fr) * 1969-12-19 1971-06-08 Christiaens Sa A Nouveau derives du 2-amino-indane, leur preparation et leur utilisation
AR206505A1 (es) * 1972-09-18 1976-07-30 Christiaens Sa A Procedimiento para obtener nuevos derivados de n-fenil-n-aminoalquil-2-aminoindano
ZA738419B (en) * 1972-11-06 1974-09-25 Christiaens Sa A New derivatives of 2-aminoindane,the preparation and use thereof
GB1462036A (en) 1973-02-05 1977-01-19 Manuf Prod Pharma Aminoindane derivatives
GB1468347A (en) * 1973-03-02 1977-03-23 Christiaens Sa A Aminoindanes

Also Published As

Publication number Publication date
WO2000076510A1 (en) 2000-12-21
EP1185267A4 (en) 2003-09-03
NZ515143A (en) 2004-05-28
PT1185267E (pt) 2006-12-29
CN1355700A (zh) 2002-06-26
IL146190A (en) 2008-11-03
NO323856B1 (no) 2007-07-16
ES2267546T3 (es) 2007-03-16
CA2376819A1 (en) 2000-12-21
EP1185267A1 (en) 2002-03-13
US6413987B1 (en) 2002-07-02
NO20016037L (no) 2002-02-11
AU5596300A (en) 2001-01-02
NO20016037D0 (no) 2001-12-10
DK1185267T3 (da) 2006-12-11
CA2376819C (en) 2008-09-02
BR0011028A (pt) 2002-02-19
ATE335482T1 (de) 2006-09-15
DE60029954D1 (de) 2006-09-21
WO2000076510A9 (en) 2002-07-04
EP1185267B1 (en) 2006-08-09
AU777517B2 (en) 2004-10-21
DE60029954T2 (de) 2007-03-08
MXPA01012632A (es) 2004-03-19
CY1105721T1 (el) 2010-12-22
JP2003501469A (ja) 2003-01-14

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