ID24957A - Turunan sulfonilamino yang menginhibisi metaloproteinase penurun matriks - Google Patents
Turunan sulfonilamino yang menginhibisi metaloproteinase penurun matriksInfo
- Publication number
- ID24957A ID24957A IDW20001501A ID20001501A ID24957A ID 24957 A ID24957 A ID 24957A ID W20001501 A IDW20001501 A ID W20001501A ID 20001501 A ID20001501 A ID 20001501A ID 24957 A ID24957 A ID 24957A
- Authority
- ID
- Indonesia
- Prior art keywords
- sulfonilamino
- metaloproteinase
- derivating
- initiating
- reducing matrix
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1881998A | 1998-02-04 | 1998-02-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
ID24957A true ID24957A (id) | 2000-08-31 |
Family
ID=21789936
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW20001501A ID24957A (id) | 1998-02-04 | 1999-02-02 | Turunan sulfonilamino yang menginhibisi metaloproteinase penurun matriks |
Country Status (18)
Country | Link |
---|---|
US (1) | US6277987B1 (id) |
EP (2) | EP1053226A1 (id) |
JP (1) | JP4750272B2 (id) |
KR (1) | KR20010040698A (id) |
CN (1) | CN1195735C (id) |
AU (1) | AU747911B2 (id) |
BR (1) | BR9909322A (id) |
CA (1) | CA2318145C (id) |
HU (1) | HUP0101176A3 (id) |
ID (1) | ID24957A (id) |
IL (1) | IL137465A0 (id) |
NO (1) | NO317977B1 (id) |
NZ (1) | NZ505968A (id) |
PL (1) | PL342009A1 (id) |
RU (1) | RU2208609C2 (id) |
SK (1) | SK11692000A3 (id) |
TR (1) | TR200002224T2 (id) |
WO (1) | WO1999042443A1 (id) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL343361A1 (en) * | 1998-04-03 | 2001-08-13 | Sankyo Co | Sulfonamide derivatives |
WO2000051993A2 (en) | 1999-03-03 | 2000-09-08 | The Procter & Gamble Company | Dihetero-substituted metalloprotease inhibitors |
CN1349498A (zh) * | 1999-03-03 | 2002-05-15 | 宝洁公司 | 含有链烯基和炔基的金属蛋白酶抑制剂 |
GB9918684D0 (en) | 1999-08-09 | 1999-10-13 | Novartis Ag | Organic compounds |
EP1088815A1 (en) * | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonyl amino acid derivatives |
WO2001023363A1 (fr) * | 1999-09-29 | 2001-04-05 | Sankyo Company, Limited | Derives de sulfonamide |
SK13352002A3 (sk) * | 2000-03-21 | 2003-05-02 | The Procter & Gamble Company | Metaloproteázové inhibítory s vedľajším heterocyklickým reťazcom |
EP1265864A1 (en) | 2000-03-21 | 2002-12-18 | The Procter & Gamble Company | Heterocyclic side chain containing, n-substituted metalloprotease inhibitors |
WO2001070693A2 (en) | 2000-03-21 | 2001-09-27 | The Procter & Gamble Company | Difluorobutyric acid derivatives and their use as metalloprotease inhibitors |
CA2404002A1 (en) * | 2000-03-24 | 2001-09-27 | Methylgene, Inc. | Inhibitors of histone deacetylase |
AU4882101A (en) * | 2000-04-28 | 2001-11-12 | Shionogi & Co., Ltd. | Mmp-12 inhibitors |
EP1174129A1 (en) * | 2000-07-17 | 2002-01-23 | Zenner, Hans Peter, Prof. Dr. med. | Use of a matrix-metalloprotease inhibitor for the treatment of cancer |
GB0103303D0 (en) | 2001-02-09 | 2001-03-28 | Novartis Ag | Organic compounds |
SE0100903D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
SE0100902D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
SE0103710D0 (sv) | 2001-11-07 | 2001-11-07 | Astrazeneca Ab | Compounds |
ES2331177T3 (es) * | 2001-12-14 | 2009-12-23 | Exelixis, Inc. | Inhibidores de adam-10 humana. |
US20050227994A1 (en) * | 2002-03-27 | 2005-10-13 | Shionogi & Co., Ltd. | Decomposition inhibitor for extracellular matrix of cartilage |
DK1511472T3 (da) * | 2002-05-29 | 2009-08-24 | Merck & Co Inc | Anvendelige forbindelser til behandling af Anthrax og hæmning af letalfaktor |
SE0202539D0 (sv) | 2002-08-27 | 2002-08-27 | Astrazeneca Ab | Compounds |
GB0221246D0 (en) * | 2002-09-13 | 2002-10-23 | Astrazeneca Ab | Compounds |
JP2007537256A (ja) | 2004-05-11 | 2007-12-20 | メルク エンド カムパニー インコーポレーテッド | N−スルホン化アミノ酸誘導体調製のためのプロセス |
GB0412553D0 (en) | 2004-06-04 | 2004-07-07 | Univ Aberdeen | Therapeutic agents for the treatment of bone conditions |
SE0401762D0 (sv) | 2004-07-05 | 2004-07-05 | Astrazeneca Ab | Novel compounds |
US7648992B2 (en) | 2004-07-05 | 2010-01-19 | Astrazeneca Ab | Hydantoin derivatives for the treatment of obstructive airway diseases |
WO2006029173A2 (en) * | 2004-09-08 | 2006-03-16 | Boys Town National Research Hospital | Treatment of glomerular basement membrane disease involving matrix metalloproteinase-12 |
US20100003276A1 (en) * | 2004-12-07 | 2010-01-07 | Hermes Jeffery D | Methods for treating anthrax and inhibiting lethal factor |
SE0403085D0 (sv) | 2004-12-17 | 2004-12-17 | Astrazeneca Ab | Novel componds |
SE0403086D0 (sv) | 2004-12-17 | 2004-12-17 | Astrazeneca Ab | Compounds |
US7576222B2 (en) * | 2004-12-28 | 2009-08-18 | Wyeth | Alkynyl-containing tryptophan derivative inhibitors of TACE/matrix metalloproteinase |
WO2007117451A2 (en) * | 2006-03-31 | 2007-10-18 | The Regents Of The University Of Michigan | A pericellular collagenase directs the 3-dimensional development of white adipose tissue |
TW200831488A (en) * | 2006-11-29 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
EP1972617A1 (en) * | 2007-03-19 | 2008-09-24 | Bracco Imaging, S.P.A. | Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors |
GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
MX2010010525A (es) | 2008-03-24 | 2010-10-25 | Novartis Ag | Inhibidores de metaloproteasa de matriz basados en aril-sulfonamida. |
EP2147684A1 (en) * | 2008-07-22 | 2010-01-27 | Bracco Imaging S.p.A | Diagnostic Agents Selective Against Metalloproteases |
EP2149568A1 (en) | 2008-07-22 | 2010-02-03 | Bracco Imaging S.p.A | Aryl-sulphonamidic dimers as metalloproteases inhibitors |
GB0817207D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
GB0817208D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | Therapeutic apsap compounds and their use |
US8557983B2 (en) | 2008-12-04 | 2013-10-15 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
US20100160322A1 (en) | 2008-12-04 | 2010-06-24 | Abbott Laboratories | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
UA108193C2 (uk) * | 2008-12-04 | 2015-04-10 | Апоптозіндукуючий засіб для лікування раку і імунних і аутоімунних захворювань | |
US8586754B2 (en) | 2008-12-05 | 2013-11-19 | Abbvie Inc. | BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases |
EP2376480B1 (en) * | 2008-12-05 | 2016-06-01 | AbbVie Inc. | Sulfonamide derivatives as bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases |
US8563735B2 (en) | 2008-12-05 | 2013-10-22 | Abbvie Inc. | Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases |
ITTO20090648A1 (it) * | 2009-08-19 | 2011-02-20 | Istituto Naz Per La Ricerca Sul Cancro | Inibitori di adam17 atti a modulare il rilascio di alcam (cd166) solubile in cellule tumorali e loro uso nel trattamento terapeutico del carcinoma ovarico epiteliale (eoc) |
US9023318B2 (en) | 2011-06-08 | 2015-05-05 | Siemens Medical Solutions Usa, Inc. | Compounds with matrix-metalloproteinase inhibitory activity and imaging agents thereof |
GB201311361D0 (en) | 2013-06-26 | 2013-08-14 | Pimco 2664 Ltd | Compounds and their therapeutic use |
AU2015367528B2 (en) | 2014-12-17 | 2020-05-14 | Pimco 2664 Limited | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use |
CN110483437B (zh) * | 2018-05-14 | 2022-12-06 | 嘉兴维眸生物科技有限公司 | 一种含五元环的化合物及其制备和应用 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1493664A1 (de) | 1964-07-16 | 1969-06-04 | Hoechst Ag | Verfahren zur Spaltung von aromatischen Sulfonsaeureamiden |
AU4267293A (en) | 1992-05-01 | 1993-11-29 | British Biotech Pharmaceuticals Limited | Use of MMP inhibitors |
US5506242A (en) * | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
US5552419A (en) * | 1993-01-06 | 1996-09-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
US5646167A (en) * | 1993-01-06 | 1997-07-08 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamix acids |
ATE191468T1 (de) | 1994-06-22 | 2000-04-15 | British Biotech Pharm | Metalloproteinase inhibitoren |
SK282833B6 (sk) | 1995-11-17 | 2002-12-03 | Warner-Lambert Company | Sulfónamidové inhibítory matricových metaloproteináz a farmaceutická kompozícia obsahujúca tieto inhibítory |
TR199800990T2 (xx) | 1995-12-08 | 1998-07-21 | Agouron Pharmaceuticals, Inc. | Metaloproteinaz inhibit�rleri, bunlar� i�eren farmas�tik bile�imler, bunlar�n farmas�tik kullan�mlar� ve bunlar�n �retiminde kullan�labilecek y�ntemler ve ara �r�nler. |
US5753653A (en) | 1995-12-08 | 1998-05-19 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
NZ325939A (en) * | 1996-01-23 | 2000-06-23 | Shionogi & Co | Sulphonated amino acid derivatives and matrix metalloproteinase inhibitors (MMP) containing these derivatives |
ES2167733T3 (es) * | 1996-05-17 | 2002-05-16 | Warner Lambert Co | Inhibidores de metaloproteinasa matricial de bifenilsulfonamida. |
EP0915086A4 (en) | 1996-05-24 | 2001-01-17 | Ono Pharmaceutical Co | PHENYLSULFONAMIDE DERIVATIVES |
BR9712792A (pt) | 1996-08-28 | 1999-12-14 | Procter & Gamble | Inibidores de metaloprotease bidentada. |
DK0923561T3 (da) | 1996-08-28 | 2003-02-24 | Procter & Gamble | Heterocykliske metalloproteaseinhibitorer |
ATE272062T1 (de) | 1996-08-28 | 2004-08-15 | Procter & Gamble | Spirocyclisch metalloprotease inhibitoren |
PT927161E (pt) | 1996-08-28 | 2003-12-31 | Procter & Gamble | Aminas ciclicas substituidas inibidoras de metaloproteases |
EP0927168B1 (en) | 1996-08-28 | 2002-11-06 | The Procter & Gamble Company | 1,3-diheterocyclic metalloprotease inhibitors |
PL331856A1 (en) | 1996-08-28 | 1999-08-16 | Procter & Gamble | Heterocyclic inhibitors of metaloprotease |
CA2264692A1 (en) * | 1996-12-17 | 1998-06-25 | Warner-Lambert Company | Use of matrix metalloproteinase inhibitors for treating neurological disorders and promoting wound healing |
US5859061A (en) * | 1997-01-17 | 1999-01-12 | Pharmacia & Upjohn Company | Bis-sulfonamides hydroxamic acids as MMP inhibitors |
CA2285372A1 (en) | 1997-04-01 | 1998-10-08 | Melwyn A. Abreo | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
US5985900A (en) * | 1997-04-01 | 1999-11-16 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
US5756545A (en) * | 1997-04-21 | 1998-05-26 | Warner-Lambert Company | Biphenysulfonamide matrix metal alloproteinase inhibitors |
AU7294098A (en) | 1997-05-09 | 1998-11-27 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
DE59802394D1 (de) | 1997-05-09 | 2002-01-24 | Hoechst Ag | Substituierte Diaminocarbonsäuren |
DE19719585A1 (de) | 1997-05-09 | 1998-11-12 | Hoechst Ag | Substituierte Diaminocarbonsäuren |
DE19719428A1 (de) | 1997-05-12 | 1998-11-19 | Hoechst Ag | Substituierte Diaminocarbonsäuren |
DE19719621A1 (de) * | 1997-05-09 | 1998-11-12 | Hoechst Ag | Sulfonylaminocarbonsäuren |
CN1198607C (zh) | 1997-07-22 | 2005-04-27 | 盐野义制药株式会社 | 治疗或预防肾小球病的组合物 |
CA2298617A1 (en) * | 1997-07-31 | 1999-02-11 | Yetunde Olabisi Taiwo | Acyclic metalloprotease inhibitors |
-
1999
- 1999-02-02 IL IL13746599A patent/IL137465A0/xx unknown
- 1999-02-02 HU HU0101176A patent/HUP0101176A3/hu unknown
- 1999-02-02 EP EP99910174A patent/EP1053226A1/en not_active Ceased
- 1999-02-02 SK SK1169-2000A patent/SK11692000A3/sk unknown
- 1999-02-02 JP JP2000532395A patent/JP4750272B2/ja not_active Expired - Fee Related
- 1999-02-02 AU AU29235/99A patent/AU747911B2/en not_active Ceased
- 1999-02-02 EP EP07120827A patent/EP1918278A1/en not_active Withdrawn
- 1999-02-02 CN CNB998027154A patent/CN1195735C/zh not_active Expired - Fee Related
- 1999-02-02 ID IDW20001501A patent/ID24957A/id unknown
- 1999-02-02 KR KR1020007008576A patent/KR20010040698A/ko not_active Application Discontinuation
- 1999-02-02 NZ NZ505968A patent/NZ505968A/xx unknown
- 1999-02-02 TR TR2000/02224T patent/TR200002224T2/xx unknown
- 1999-02-02 CA CA002318145A patent/CA2318145C/en not_active Expired - Fee Related
- 1999-02-02 BR BR9909322-7A patent/BR9909322A/pt not_active IP Right Cessation
- 1999-02-02 WO PCT/EP1999/000646 patent/WO1999042443A1/en not_active Application Discontinuation
- 1999-02-02 RU RU2000123166/04A patent/RU2208609C2/ru not_active IP Right Cessation
- 1999-02-02 PL PL99342009A patent/PL342009A1/xx not_active Application Discontinuation
- 1999-02-03 US US09/243,854 patent/US6277987B1/en not_active Expired - Fee Related
-
2000
- 2000-07-11 NO NO20003565A patent/NO317977B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PL342009A1 (en) | 2001-05-07 |
EP1053226A1 (en) | 2000-11-22 |
CA2318145A1 (en) | 1999-08-26 |
JP4750272B2 (ja) | 2011-08-17 |
HUP0101176A3 (en) | 2002-06-28 |
JP2002503720A (ja) | 2002-02-05 |
SK11692000A3 (sk) | 2001-02-12 |
US6277987B1 (en) | 2001-08-21 |
NO20003565L (no) | 2000-10-03 |
EP1918278A1 (en) | 2008-05-07 |
NO20003565D0 (no) | 2000-07-11 |
AU2923599A (en) | 1999-09-06 |
BR9909322A (pt) | 2000-12-05 |
KR20010040698A (ko) | 2001-05-15 |
NO317977B1 (no) | 2005-01-17 |
CA2318145C (en) | 2009-10-27 |
CN1290250A (zh) | 2001-04-04 |
WO1999042443A1 (en) | 1999-08-26 |
IL137465A0 (en) | 2001-07-24 |
RU2208609C2 (ru) | 2003-07-20 |
TR200002224T2 (tr) | 2000-12-21 |
NZ505968A (en) | 2003-03-28 |
AU747911B2 (en) | 2002-05-30 |
HUP0101176A2 (hu) | 2001-09-28 |
CN1195735C (zh) | 2005-04-06 |
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