ID24173A - 1,2,3,4,5,6 heksahidro-2-6-metano-3-benzazosin-10-ol, proses pembuatan dan penggunannya untuk obat-obatan - Google Patents

1,2,3,4,5,6 heksahidro-2-6-metano-3-benzazosin-10-ol, proses pembuatan dan penggunannya untuk obat-obatan

Info

Publication number: ID24173A
Authority: ID; Indonesia
Prior art keywords: heksahidro; benzazosin; metano; medicines; making
Prior art date: 1997-09-12

Application number

IDW20000461A

Other languages

English (en)

Inventor

Matthias Grauert

Andrian Carter

W D Bechtel

Thomas Weiser

Rainer Palluk

Uwe Pschorn

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-12

Filing date

1998-09-09

Publication date

2000-07-13

1998-09-09 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2000-07-13 Publication of ID24173A publication Critical patent/ID24173A/id

Links

239000003814 drug Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

IDW20000461A 1997-09-12 1998-09-09 1,2,3,4,5,6 heksahidro-2-6-metano-3-benzazosin-10-ol, proses pembuatan dan penggunannya untuk obat-obatan ID24173A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19740110A DE19740110A1 (de)	1997-09-12	1997-09-12	Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number	Publication Date
ID24173A true ID24173A (id)	2000-07-13

Family

ID=7842134

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW20000461A ID24173A (id)	1997-09-12	1998-09-09	1,2,3,4,5,6 heksahidro-2-6-metano-3-benzazosin-10-ol, proses pembuatan dan penggunannya untuk obat-obatan

Country Status (38)

Country	Link
US (1)	US6455538B1 (id)
EP (1)	EP1015433B1 (id)
JP (1)	JP3827528B2 (id)
KR (1)	KR100601008B1 (id)
CN (1)	CN1166640C (id)
AR (1)	AR017095A1 (id)
AT (1)	ATE267811T1 (id)
AU (1)	AU751036B2 (id)
BG (1)	BG64418B1 (id)
BR (1)	BR9812443A (id)
CA (1)	CA2302347C (id)
CO (1)	CO5011117A1 (id)
CZ (1)	CZ296909B6 (id)
DE (2)	DE19740110A1 (id)
DK (1)	DK1015433T3 (id)
EE (1)	EE04398B1 (id)
ES (1)	ES2222612T3 (id)
HR (1)	HRP980502B1 (id)
HU (1)	HUP0004588A3 (id)
ID (1)	ID24173A (id)
IL (1)	IL134572A (id)
MY (1)	MY120550A (id)
NO (1)	NO315650B1 (id)
NZ (1)	NZ503710A (id)
PE (1)	PE122899A1 (id)
PL (1)	PL198486B1 (id)
PT (1)	PT1015433E (id)
RS (1)	RS49888B (id)
RU (1)	RU2218334C2 (id)
SA (1)	SA98190765B1 (id)
SK (1)	SK284670B6 (id)
TR (1)	TR200000697T2 (id)
TW (1)	TW505645B (id)
UA (1)	UA61973C2 (id)
UY (2)	UY25175A1 (id)
WO (1)	WO1999014199A1 (id)
YU (1)	YU12000A (id)
ZA (1)	ZA988285B (id)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19826365A1 (de) *	1998-06-12	1999-12-16	Gruenenthal Gmbh	Verwendung von Benzomorphanderivaten als Analgetikum
US6355652B1 (en)	1999-11-27	2002-03-12	Boehringer Ingelheim Pharma Kg	Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and their use as pharmaceutical compositions
DE19957156A1 (de) *	1999-11-27	2001-05-31	Boehringer Ingelheim Pharma	Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel
DE10204276A1 (de) *	2002-02-02	2003-08-07	Boehringer Ingelheim Pharma	N-Allyloxyethyl-1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel
US6683089B2 (en)	2002-02-02	2004-01-27	Boehringer Ingelheim Pharma Gmbh & Co. Kg	N-allyoxyethyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine-10-ols
US20040019075A1 (en) *	2002-05-29	2004-01-29	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New formulation for the parenteral application of crobenetine
US6828311B2 (en)	2002-05-29	2004-12-07	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Formulation for the parenteral application of a sodium channel blocker
DE10223783A1 (de) *	2002-05-29	2003-12-11	Boehringer Ingelheim Pharma	Neue Formulierung zur parenteralen Applikation eines Na-Kanal-Blockers
DE10226814A1 (de) *	2002-06-15	2004-01-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittelkombinationen zur Behandlung ischämischer Zustände
US20030235576A1 (en) *	2002-06-15	2003-12-25	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New drug combinations for the treatment of ischaemic conditions
PT1963280E (pt)	2005-12-22	2016-02-02	Newron Pharm Spa	Derivados de 2-feniletilamino como cálcio e/ou moduladores do canal de sódio
EP2155663B1 (en)	2007-06-15	2017-11-29	Newron Pharmaceuticals S.p.A.	Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives and their use as sodium and/or calcium channel modulators
US9447029B2 (en)	2011-06-27	2016-09-20	Newron Pharmaceuticals S.P.A.	Fluorinated arylalkylaminocarboxamide derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2828039A1 (de) *	1978-06-26	1980-01-10	Boehringer Sohn Ingelheim	2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US4208523A (en)	1978-11-30	1980-06-17	Sterling Drug Inc.	11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
US5607941A (en) *	1992-06-26	1997-03-04	Boehringer Ingelheim Kg	Useful for treating neurodegenerative diseases
DE4121821A1 (de) *	1991-07-02	1993-01-14	Boehringer Ingelheim Kg	Neue benzomorphane und ihre verwendung als arzneimittel
DE19528472A1 (de) *	1995-08-03	1997-02-06	Boehringer Ingelheim Kg	Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan

1997
- 1997-09-12 DE DE19740110A patent/DE19740110A1/de not_active Ceased
1998
- 1998-09-08 PE PE1998000847A patent/PE122899A1/es not_active Application Discontinuation
- 1998-09-09 DK DK98950009T patent/DK1015433T3/da active
- 1998-09-09 RS YUP-120/00A patent/RS49888B/sr unknown
- 1998-09-09 NZ NZ503710A patent/NZ503710A/xx unknown
- 1998-09-09 AT AT98950009T patent/ATE267811T1/de not_active IP Right Cessation
- 1998-09-09 ES ES98950009T patent/ES2222612T3/es not_active Expired - Lifetime
- 1998-09-09 JP JP2000511750A patent/JP3827528B2/ja not_active Expired - Fee Related
- 1998-09-09 KR KR1020007002562A patent/KR100601008B1/ko not_active IP Right Cessation
- 1998-09-09 DE DE59811477T patent/DE59811477D1/de not_active Expired - Fee Related
- 1998-09-09 WO PCT/EP1998/005734 patent/WO1999014199A1/de active IP Right Grant
- 1998-09-09 RU RU2000109358/04A patent/RU2218334C2/ru not_active IP Right Cessation
- 1998-09-09 TR TR2000/00697T patent/TR200000697T2/xx unknown
- 1998-09-09 HU HU0004588A patent/HUP0004588A3/hu unknown
- 1998-09-09 IL IL13457298A patent/IL134572A/xx not_active IP Right Cessation
- 1998-09-09 ID IDW20000461A patent/ID24173A/id unknown
- 1998-09-09 EP EP98950009A patent/EP1015433B1/de not_active Expired - Lifetime
- 1998-09-09 PT PT98950009T patent/PT1015433E/pt unknown
- 1998-09-09 AU AU96242/98A patent/AU751036B2/en not_active Ceased
- 1998-09-09 BR BR9812443-9A patent/BR9812443A/pt not_active Application Discontinuation
- 1998-09-09 CN CNB988090155A patent/CN1166640C/zh not_active Expired - Fee Related
- 1998-09-09 UY UY25175A patent/UY25175A1/es not_active IP Right Cessation
- 1998-09-09 CZ CZ20000894A patent/CZ296909B6/cs not_active IP Right Cessation
- 1998-09-09 UA UA2000042088A patent/UA61973C2/uk unknown
- 1998-09-09 EE EEP200000129A patent/EE04398B1/xx not_active IP Right Cessation
- 1998-09-09 SK SK334-2000A patent/SK284670B6/sk not_active IP Right Cessation
- 1998-09-09 PL PL339061A patent/PL198486B1/pl not_active IP Right Cessation
- 1998-09-09 CA CA002302347A patent/CA2302347C/en not_active Expired - Fee Related
- 1998-09-10 CO CO98052134A patent/CO5011117A1/es unknown
- 1998-09-10 TW TW087115042A patent/TW505645B/zh active
- 1998-09-10 ZA ZA988285A patent/ZA988285B/xx unknown
- 1998-09-10 MY MYPI98004142A patent/MY120550A/en unknown
- 1998-09-11 AR ARP980104530A patent/AR017095A1/es active Pending
- 1998-09-11 HR HR980502A patent/HRP980502B1/xx not_active IP Right Cessation
- 1998-11-16 SA SA98190765A patent/SA98190765B1/ar unknown
1999
- 1999-03-22 UY UY25439A patent/UY25439A1/es not_active IP Right Cessation
2000
- 2000-03-02 YU YU12000A patent/YU12000A/sh unknown
- 2000-03-09 BG BG104232A patent/BG64418B1/bg active Active
- 2000-03-10 US US09/523,473 patent/US6455538B1/en not_active Expired - Lifetime
- 2000-03-10 NO NO20001288A patent/NO315650B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
RS49888B (sr)	2008-08-07
EE04398B1 (et)	2004-12-15
EP1015433B1 (de)	2004-05-26
PE122899A1 (es)	1999-12-06
PL339061A1 (en)	2000-12-04
YU12000A (sh)	2002-11-15
CA2302347A1 (en)	1999-03-25
CA2302347C (en)	2008-06-17
DK1015433T3 (da)	2004-09-27
NO20001288D0 (no)	2000-03-10
DE19740110A1 (de)	1999-03-18
EP1015433A1 (de)	2000-07-05
BR9812443A (pt)	2000-09-26
ATE267811T1 (de)	2004-06-15
HUP0004588A2 (hu)	2001-07-30
TW505645B (en)	2002-10-11
TR200000697T2 (tr)	2001-01-22
CN1166640C (zh)	2004-09-15
AU751036B2 (en)	2002-08-08
PL198486B1 (pl)	2008-06-30
AR017095A1 (es)	2001-08-22
SA98190765B1 (ar)	2006-06-10
UY25439A1 (es)	1999-11-17
CO5011117A1 (es)	2001-02-28
CZ2000894A3 (cs)	2000-09-13
WO1999014199A1 (de)	1999-03-25
NO20001288L (no)	2000-03-13
IL134572A (en)	2005-05-17
KR100601008B1 (ko)	2006-07-19
ZA988285B (en)	1999-03-12
BG64418B1 (bg)	2005-01-31
NZ503710A (en)	2002-04-26
RU2218334C2 (ru)	2003-12-10
JP3827528B2 (ja)	2006-09-27
HRP980502B1 (en)	2005-02-28
IL134572A0 (en)	2001-04-30
MY120550A (en)	2005-11-30
NO315650B1 (no)	2003-10-06
EE200000129A (et)	2001-02-15
BG104232A (en)	2000-10-31
CN1269790A (zh)	2000-10-11
UA61973C2 (en)	2003-12-15
SK3342000A3 (en)	2000-09-12
CZ296909B6 (cs)	2006-07-12
ES2222612T3 (es)	2005-02-01
HUP0004588A3 (en)	2002-10-28
KR20010023879A (ko)	2001-03-26
UY25175A1 (es)	2000-12-29
HRP980502A2 (en)	1999-06-30
SK284670B6 (sk)	2005-08-04
PT1015433E (pt)	2004-08-31
JP2001516747A (ja)	2001-10-02
US6455538B1 (en)	2002-09-24
DE59811477D1 (de)	2004-07-01
AU9624298A (en)	1999-04-05

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ID18521A (id)	1998-04-16	Proses asetoksilasi olefin-olefin
ID22511A (id)	1999-10-28	Lampu fluoresen dan metoda pembuatannya
ID24173A (id)	2000-07-13	1,2,3,4,5,6 heksahidro-2-6-metano-3-benzazosin-10-ol, proses pembuatan dan penggunannya untuk obat-obatan
ID23304A (id)	2000-04-05	Turunan-turunan diaza-spiro [3,5] nonana, proses pembuatan dan penggunaannya
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