ATE204279T1 - Diaza-spiro(3,5)nonan-derivate - Google Patents

Diaza-spiro(3,5)nonan-derivate

Info

Publication number: ATE204279T1
Authority: AT; Austria
Prior art keywords: nonanene; diaza; spiro; derivatives; nonanene derivatives
Prior art date: 1998-06-12

Application number

AT99110943T

Other languages

English (en)

Inventor

Geo Adam

Andrea Cesura

Francois Jenck

Sabine Kolczewski

Stephan Roever

Juergen Wichmann

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-12

Filing date

1999-06-07

Publication date

2001-09-15

1999-06-07 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2001-09-15 Application granted granted Critical

2001-09-15 Publication of ATE204279T1 publication Critical patent/ATE204279T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

AT99110943T 1998-06-12 1999-06-07 Diaza-spiro(3,5)nonan-derivate ATE204279T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP98110804		1998-06-12

Publications (1)

Publication Number	Publication Date
ATE204279T1 true ATE204279T1 (de)	2001-09-15

Family

ID=8232114

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99110943T ATE204279T1 (de)	1998-06-12	1999-06-07	Diaza-spiro(3,5)nonan-derivate

Country Status (28)

Country	Link
US (1)	US6113527A (de)
EP (1)	EP0970957B1 (de)
JP (1)	JP3286268B2 (de)
KR (1)	KR100344732B1 (de)
CN (1)	CN1107066C (de)
AR (1)	AR019859A1 (de)
AT (1)	ATE204279T1 (de)
AU (1)	AU743983B2 (de)
BR (1)	BR9902651A (de)
CA (1)	CA2274202A1 (de)
DE (1)	DE69900220T2 (de)
DK (1)	DK0970957T3 (de)
ES (1)	ES2162503T3 (de)
HR (1)	HRP990188A2 (de)
HU (1)	HU220894B1 (de)
ID (1)	ID23304A (de)
IL (1)	IL130377A0 (de)
MA (1)	MA26644A1 (de)
NO (1)	NO312590B1 (de)
NZ (1)	NZ336189A (de)
PE (1)	PE20000548A1 (de)
PL (1)	PL333695A1 (de)
PT (1)	PT970957E (de)
SG (1)	SG79259A1 (de)
SI (1)	SI0970957T1 (de)
TR (1)	TR199901381A3 (de)
YU (1)	YU26499A (de)
ZA (1)	ZA993852B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030040479A1 (en) *	2001-07-02	2003-02-27	Omeros Corporation	Rotational intrathecal analgesia method and device
CA2490386A1 (en) *	2001-07-02	2003-01-16	Omeros Corporation	Method for producing analgesia comprising administration of an opioid receptor agonist in rotation with an opioid receptor like-1 receptor agonist
US7566728B2 (en)	2002-03-29	2009-07-28	Mitsubishi Tanabe Pharma Corporation	Remedy for sleep disturbance
JP2005289816A (ja)	2002-05-14	2005-10-20	Banyu Pharmaceut Co Ltd	ベンズイミダゾール誘導体
JP4749715B2 (ja)	2002-07-05	2011-08-17	ターガセプト，インコーポレイテッド	Ｎ−アリールジアザスピロ環式化合物、並びにその製造及び使用方法
WO2004022558A2 (en) *	2002-09-09	2004-03-18	Janssen Pharmaceutica, N.V.	Hydroxy alkyl substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of orl-1 receptor mediated disorders
GB0323204D0 (en) *	2003-10-03	2003-11-05	Novartis Ag	Organic compounds
US20050228023A1 (en) *	2003-12-19	2005-10-13	Sri International	Agonist and antagonist ligands of the nociceptin receptor
US20060178390A1 (en) *	2004-08-02	2006-08-10	Alfonzo Jordan	1,3,8-Triazaspiro[4,5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
CN101022801A (zh) *	2004-08-20	2007-08-22	塔加西普特公司	N－芳基二氮杂螺环化合物在成瘾治疗中的用途
US20080247964A1 (en) *	2006-05-08	2008-10-09	Yuelian Xu	Substituted azaspiro derivatives
WO2008067167A1 (en) *	2006-11-28	2008-06-05	Janssen Pharmaceutica N.V.	Salts of 3-(3-amino-2-(r)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one
CN101679430B (zh) *	2007-04-09	2013-12-25	詹森药业有限公司	用于治疗焦虑和抑郁症的作为orl-1受体的配体的1,3,8-三取代-1,3,8-三氮杂-螺[4.5]癸-4-酮衍生物
KR101704226B1 (ko)	2015-06-30	2017-02-07	현대자동차주식회사	자동차의 쿼터글라스 어셈블리
TW202340202A (zh) *	2021-12-22	2023-10-16	美國加利福尼亞大學董事會	Gtp酶抑制劑及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5756743A (en) *	1996-04-10	1998-05-26	Hoechst Marion Roussel Inc.	Spiro cyclopent b!indole-piperidines!

1999
- 1999-06-07 AT AT99110943T patent/ATE204279T1/de not_active IP Right Cessation
- 1999-06-07 PT PT99110943T patent/PT970957E/pt unknown
- 1999-06-07 DE DE69900220T patent/DE69900220T2/de not_active Expired - Lifetime
- 1999-06-07 SI SI9930008T patent/SI0970957T1/xx unknown
- 1999-06-07 EP EP99110943A patent/EP0970957B1/de not_active Expired - Lifetime
- 1999-06-07 DK DK99110943T patent/DK0970957T3/da active
- 1999-06-07 ES ES99110943T patent/ES2162503T3/es not_active Expired - Lifetime
- 1999-06-08 ID IDP990543D patent/ID23304A/id unknown
- 1999-06-08 PE PE1999000487A patent/PE20000548A1/es not_active Application Discontinuation
- 1999-06-08 ZA ZA9903852A patent/ZA993852B/xx unknown
- 1999-06-09 HU HU9901911A patent/HU220894B1/hu not_active IP Right Cessation
- 1999-06-09 CA CA002274202A patent/CA2274202A1/en not_active Abandoned
- 1999-06-09 NZ NZ336189A patent/NZ336189A/xx unknown
- 1999-06-09 IL IL13037799A patent/IL130377A0/xx unknown
- 1999-06-09 SG SG9903066A patent/SG79259A1/en unknown
- 1999-06-10 MA MA25616A patent/MA26644A1/fr unknown
- 1999-06-10 KR KR1019990021485A patent/KR100344732B1/ko not_active IP Right Cessation
- 1999-06-10 JP JP16357099A patent/JP3286268B2/ja not_active Expired - Fee Related
- 1999-06-10 AR ARP990102763A patent/AR019859A1/es active IP Right Grant
- 1999-06-10 AU AU34987/99A patent/AU743983B2/en not_active Ceased
- 1999-06-10 YU YU26499A patent/YU26499A/sh unknown
- 1999-06-11 PL PL99333695A patent/PL333695A1/xx unknown
- 1999-06-11 US US09/330,851 patent/US6113527A/en not_active Expired - Fee Related
- 1999-06-11 HR HR98110804.6A patent/HRP990188A2/hr not_active Application Discontinuation
- 1999-06-11 CN CN99108373A patent/CN1107066C/zh not_active Expired - Fee Related
- 1999-06-11 BR BR9902651-1A patent/BR9902651A/pt not_active Application Discontinuation
- 1999-06-11 TR TR1999/01381A patent/TR199901381A3/tr unknown
- 1999-06-11 NO NO19992873A patent/NO312590B1/no unknown

Also Published As

Publication number	Publication date
AR019859A1 (es)	2002-03-20
JP2000053679A (ja)	2000-02-22
ID23304A (id)	2000-04-05
EP0970957A1 (de)	2000-01-12
YU26499A (sh)	2002-09-19
IL130377A0 (en)	2000-06-01
AU3498799A (en)	1999-12-23
ES2162503T3 (es)	2001-12-16
NZ336189A (en)	2000-10-27
SI0970957T1 (de)	2001-12-31
TR199901381A2 (xx)	2000-01-21
SG79259A1 (en)	2001-03-20
CA2274202A1 (en)	1999-12-12
TR199901381A3 (tr)	2000-01-21
KR20000006060A (ko)	2000-01-25
PT970957E (pt)	2002-02-28
BR9902651A (pt)	2000-05-16
DE69900220T2 (de)	2002-05-08
NO992873L (no)	1999-12-13
HRP990188A2 (en)	2000-02-29
NO312590B1 (no)	2002-06-03
KR100344732B1 (ko)	2002-07-19
ZA993852B (en)	1999-12-13
MA26644A1 (fr)	2004-12-20
DK0970957T3 (da)	2001-12-03
HU220894B1 (en)	2002-06-29
US6113527A (en)	2000-09-05
CN1242366A (zh)	2000-01-26
PE20000548A1 (es)	2000-07-15
DE69900220D1 (de)	2001-09-20
NO992873D0 (no)	1999-06-11
PL333695A1 (en)	1999-12-20
JP3286268B2 (ja)	2002-05-27
AU743983B2 (en)	2002-02-14
EP0970957B1 (de)	2001-08-16
HU9901911D0 (en)	1999-08-30
HUP9901911A1 (hu)	2000-05-28
CN1107066C (zh)	2003-04-30

Legal Events

Date	Code	Title	Description
2002-01-15	UEP	Publication of translation of european patent specification
2012-03-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE435861T1 (de)	2009-07-15	12,13-cyclopropan-epothilonderivate
DE69736711D1 (de)	2006-11-02	Substituierte 6,5-heterobicyclische-derivate
DK0925298T3 (da)	2004-08-09	Substituerede 6,6-heterobicykliske derivater
ID29241A (id)	2001-08-16	Turunan-turunan kinolin teranelasi-1,2
DK1000048T3 (da)	2003-03-03	Substituerede 1,2,3,4-tetrahydronapthalenderivater
ID19773A (id)	1998-07-30	Turunan-turunan 1,3,8-triaza-spiro (4,5) dekan-4-ona tersubtitusi-8
ATE236136T1 (de)	2003-04-15	Benzosulfonderivate
ATE259810T1 (de)	2004-03-15	Phenyl-xanthinderivate
DE69718771D1 (de)	2003-03-06	Substituierte 1,2,3,4-tetrahydronaphthalinderivate
ATE212635T1 (de)	2002-02-15	1,3,8-triazaspiro(4,5)decan-4-on-derivate
DE69821009D1 (de)	2004-02-12	6,9-verbrückte erythromycin-derivate
PT928790E (pt)	2003-07-31	Derivados de tiazolo
ATE239750T1 (de)	2003-05-15	6,11-verbrückte erythromycinderivate
DK0922050T3 (da)	2003-11-24	3-Descladinose-2,3-anhydroerythromycin-derivater
ATE204279T1 (de)	2001-09-15	Diaza-spiro(3,5)nonan-derivate
EE04089B1 (et)	2003-08-15	1,3,4-oksadiasolooni derivaadid
PT1056716E (pt)	2003-04-30	Derivados de ciclo-hexanodiolo
ATE233253T1 (de)	2003-03-15	Chromanderivate
ATE234839T1 (de)	2003-04-15	4,5-azolo-oxindole
PT1123283E (pt)	2004-09-30	Derivados de tiazole
PT1129079E (pt)	2006-05-31	Derivados de triazina 2,4-dissubstituidos
BR9701404A (pt)	1998-11-03	Derivados de 1,25-diidróxi-16,22,23-trisdeidro-colecal-ciferol
PT928793E (pt)	2002-10-31	Derivados de tiazol