HUT77631A - Eljárás a levobupivakain és származékai rezolválására - Google Patents

Eljárás a levobupivakain és származékai rezolválására

Info

Publication number
HUT77631A
HUT77631A HU9702372A HU9702372A HUT77631A HU T77631 A HUT77631 A HU T77631A HU 9702372 A HU9702372 A HU 9702372A HU 9702372 A HU9702372 A HU 9702372A HU T77631 A HUT77631 A HU T77631A
Authority
HU
Hungary
Prior art keywords
pct
levobupivacaine
derivates
resolving
produce
Prior art date
Application number
HU9702372A
Other languages
English (en)
Other versions
HU227420B1 (en
Inventor
Marianne Langstone
Benjamin Mark Skead
Original Assignee
Darwin Discovery Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9421476A external-priority patent/GB9421476D0/en
Priority claimed from GBGB9504926.8A external-priority patent/GB9504926D0/en
Application filed by Darwin Discovery Limited filed Critical Darwin Discovery Limited
Publication of HUT77631A publication Critical patent/HUT77631A/hu
Publication of HU227420B1 publication Critical patent/HU227420B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
HU9702372A 1994-10-25 1995-10-23 Produce for resolving of levobupivacaine and its derivates HU227420B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9421476A GB9421476D0 (en) 1994-10-25 1994-10-25 Process and salt
GBGB9504926.8A GB9504926D0 (en) 1995-03-10 1995-03-10 Crystallisation
PCT/GB1995/002513 WO1996012699A1 (en) 1994-10-25 1995-10-23 Crystallisation of levobupivacaine and analogues thereof

Publications (2)

Publication Number Publication Date
HUT77631A true HUT77631A (hu) 1998-06-29
HU227420B1 HU227420B1 (en) 2011-05-30

Family

ID=26305863

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9702372A HU227420B1 (en) 1994-10-25 1995-10-23 Produce for resolving of levobupivacaine and its derivates

Country Status (16)

Country Link
US (1) US5994548A (hu)
EP (1) EP0788480B1 (hu)
JP (1) JP3911545B2 (hu)
AT (1) ATE245629T1 (hu)
AU (1) AU698637B2 (hu)
CA (1) CA2200355C (hu)
DE (1) DE69531356T2 (hu)
DK (1) DK0788480T3 (hu)
ES (1) ES2202375T3 (hu)
FI (1) FI117438B (hu)
HU (1) HU227420B1 (hu)
MX (1) MX9703024A (hu)
NO (1) NO309266B1 (hu)
PL (1) PL183210B1 (hu)
PT (1) PT788480E (hu)
WO (1) WO1996012699A1 (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0002246A (pt) * 2000-04-06 2003-04-15 Cristalia Prod Quimicos Farm Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis
BRPI0104491B8 (pt) * 2001-10-10 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica.
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
EP1575569B1 (en) 2002-12-13 2010-09-29 Durect Corporation Oral drug delivery system comprising high viscosity liquid carrier materials
US7094812B2 (en) * 2003-04-24 2006-08-22 Xerox Corporations Colorant compositions
US6790267B1 (en) * 2003-04-24 2004-09-14 Xerox Corporation Colorant compositions
SI2767292T1 (sl) 2004-09-17 2017-01-31 Durect Corporation Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjem
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
WO2007123405A1 (en) * 2006-04-25 2007-11-01 Dishman Pharmaceuticals And Chemicals Ltd. Ropivacaine hydrochloride anhydrate and the preparation thereof
DK2117521T3 (da) 2006-11-03 2012-09-03 Durect Corp Transdermale indgivelsessystemer omfattende bupivacain
US8415401B2 (en) 2007-12-06 2013-04-09 Durect Corporation Oral pharmaceutical dosage forms
DK2234974T3 (da) * 2008-01-15 2012-06-25 Pharmathen Sa Fremgangsmåde til fremstilling af (S)-1-alkyl-2',6'-pipecoloxylidid-forbindelse
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
CN103073484B (zh) * 2013-01-28 2014-10-22 山东诚创医药技术开发有限公司 一种甲哌卡因及其光学对映体的制备方法
CN105120659A (zh) 2013-03-15 2015-12-02 度瑞公司 用于降低溶解可变性的具有流变改性剂的组合物
BR112019013192A2 (pt) * 2016-12-26 2019-12-10 Cellix Bio Private Ltd composto e composição farmacêutica
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE341404B (hu) * 1967-05-18 1971-12-27 Sterling Drug Inc
US4695576A (en) * 1984-07-09 1987-09-22 Astra Lake Medel Aktiebolag L-N-n-propylpipecolic acid-2,6-xylidide

Also Published As

Publication number Publication date
PL183210B1 (pl) 2002-06-28
JPH10507464A (ja) 1998-07-21
CA2200355C (en) 2007-03-06
AU698637B2 (en) 1998-11-05
NO309266B1 (no) 2001-01-08
EP0788480B1 (en) 2003-07-23
FI117438B (fi) 2006-10-13
WO1996012699A1 (en) 1996-05-02
PL319829A1 (en) 1997-09-01
FI971711A (fi) 1997-04-22
US5994548A (en) 1999-11-30
NO971903D0 (no) 1997-04-24
NO971903L (no) 1997-04-24
DE69531356T2 (de) 2004-05-27
MX9703024A (es) 1997-10-31
EP0788480A1 (en) 1997-08-13
ATE245629T1 (de) 2003-08-15
PT788480E (pt) 2003-12-31
DK0788480T3 (da) 2003-09-29
CA2200355A1 (en) 1996-05-02
FI971711A0 (fi) 1997-04-22
HU227420B1 (en) 2011-05-30
JP3911545B2 (ja) 2007-05-09
ES2202375T3 (es) 2004-04-01
DE69531356D1 (de) 2003-08-28
AU3704895A (en) 1996-05-15

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Legal Events

Date Code Title Description
DGB9 Succession in title of applicant

Owner name: DARWIN DISCOVERY LIMITED, GB