HUT61311A - Process for producing /1,2,4/triazolo/1,5-a//1,3,5/-traizine and pyrazolo/2,3-a//1,3,5/-triazine derivatives and pharmaceutical compositions comprising same as active ingredient - Google Patents

Process for producing /1,2,4/triazolo/1,5-a//1,3,5/-traizine and pyrazolo/2,3-a//1,3,5/-triazine derivatives and pharmaceutical compositions comprising same as active ingredient

Info

Publication number
HUT61311A
HUT61311A HU911789A HU178991A HUT61311A HU T61311 A HUT61311 A HU T61311A HU 911789 A HU911789 A HU 911789A HU 178991 A HU178991 A HU 178991A HU T61311 A HUT61311 A HU T61311A
Authority
HU
Hungary
Prior art keywords
traizine
triazolo
pyrazolo
producing
active ingredient
Prior art date
Application number
HU911789A
Other languages
English (en)
Other versions
HU911789D0 (en
Inventor
Peter William Rodney Caulkett
Geraint Jones
Simon Martin Poucher
Michael George Collis
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909011913A external-priority patent/GB9011913D0/en
Priority claimed from GB909011914A external-priority patent/GB9011914D0/en
Priority claimed from GB919101380A external-priority patent/GB9101380D0/en
Priority claimed from GB919101379A external-priority patent/GB9101379D0/en
Priority claimed from GB919104125A external-priority patent/GB9104125D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of HU911789D0 publication Critical patent/HU911789D0/hu
Publication of HUT61311A publication Critical patent/HUT61311A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
HU911789A 1990-05-29 1991-05-29 Process for producing /1,2,4/triazolo/1,5-a//1,3,5/-traizine and pyrazolo/2,3-a//1,3,5/-triazine derivatives and pharmaceutical compositions comprising same as active ingredient HUT61311A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB909011913A GB9011913D0 (en) 1990-05-29 1990-05-29 Azole derivatives
GB909011914A GB9011914D0 (en) 1990-05-29 1990-05-29 Heterocyclic compounds
GB919101380A GB9101380D0 (en) 1991-01-22 1991-01-22 Azole derivatives
GB919101379A GB9101379D0 (en) 1991-01-22 1991-01-22 Heterocyclic compounds
GB919104125A GB9104125D0 (en) 1991-02-27 1991-02-27 Azole derivatives

Publications (2)

Publication Number Publication Date
HU911789D0 HU911789D0 (en) 1991-12-30
HUT61311A true HUT61311A (en) 1992-12-28

Family

ID=27516979

Family Applications (1)

Application Number Title Priority Date Filing Date
HU911789A HUT61311A (en) 1990-05-29 1991-05-29 Process for producing /1,2,4/triazolo/1,5-a//1,3,5/-traizine and pyrazolo/2,3-a//1,3,5/-triazine derivatives and pharmaceutical compositions comprising same as active ingredient

Country Status (20)

Country Link
US (1) US5270311A (hu)
EP (1) EP0459702A1 (hu)
JP (1) JP2504879B2 (hu)
KR (1) KR910020012A (hu)
CN (1) CN1056879A (hu)
AP (1) AP248A (hu)
AU (1) AU642494B2 (hu)
CA (1) CA2043424A1 (hu)
CS (1) CS159591A3 (hu)
FI (1) FI912563A (hu)
GB (1) GB2244487B (hu)
HU (1) HUT61311A (hu)
IE (1) IE911818A1 (hu)
IL (1) IL98316A (hu)
NO (1) NO178401C (hu)
NZ (1) NZ238288A (hu)
OA (1) OA09358A (hu)
PT (1) PT97776A (hu)
RO (1) RO109542B1 (hu)
YU (1) YU47812B (hu)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356894A (en) * 1990-05-29 1994-10-18 Rodney Peter W Morpholinyl substituted [1,2,4]-triazolo[1,5-a]triazine as antagonist
GB2244487B (en) * 1990-05-29 1994-02-02 Ici Plc Azole derivatives
GB9226735D0 (en) * 1992-12-22 1993-02-17 Ici Plc Azole derivatives
GB9111130D0 (en) * 1991-05-23 1991-07-17 Ici Plc Azole derivatives
GB9111131D0 (en) * 1991-05-23 1991-07-17 Ici Plc Heterocyclic compounds
GB9125001D0 (en) * 1991-11-25 1992-01-22 Ici Plc Heterocyclic compounds
GB9125002D0 (en) * 1991-11-25 1992-01-22 Ici Plc Azole derivatives
GB9124968D0 (en) * 1991-11-25 1992-01-22 Ici Plc Chemical process
CA2144330A1 (en) * 1993-07-27 1995-02-09 Fumio Suzuki A therapeutic agent for parkinson's disease
CA2148502A1 (en) * 1993-09-06 1995-03-16 Fumio Suzuki Antidepressants
DE69820866T2 (de) 1997-03-24 2004-12-30 Kyowa Hakko Kogyo Co., Ltd. [1,2,4]TRIAZOLO[1,5-c]PYRIMIDIN-DERIVATE
US6060481A (en) * 1998-05-28 2000-05-09 The Penn State Research Foundation Method for improving insulin sensitivity using an adenosine receptor antagonist
KR20010087361A (ko) 1998-09-22 2001-09-15 히라타 다다시 [1,2,4]트리아졸로[1,5-ｃ]피리미딘 유도체
JPWO2004029056A1 (ja) * 2002-09-24 2006-01-26 協和醗酵工業株式会社 ［１，２，４］トリアゾロ［１，５−ｃ］ピリミジン誘導体
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
EP1615930A2 (en) 2003-04-09 2006-01-18 Biogen Idec MA, Inc. Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagonists
WO2004092172A2 (en) * 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolo[1,5-c]pyrimidines and pyrazolo[1,5-c]pyrimidines useful as a2a adenosin e receptor antagonists
DE602004018637D1 (de) 2003-04-09 2009-02-05 Biogen Idec Inc A2a-adenosinrezeptorantagonisten
EP1615931A1 (en) 2003-04-09 2006-01-18 Biogen Idec MA Inc. Triazolopyrazines and methods of making and using the same
WO2004110454A1 (ja) * 2003-06-13 2004-12-23 Ishihara Sangyo Kaisha, Ltd. アデノシンＡ2ａ受容体アゴニストの投与が必要な疾患を治療又は予防するための組成物
CA2594860A1 (en) 2005-01-14 2006-07-20 Millennium Pharmaceuticals, Inc. Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity
RU2015126797A (ru) 2012-12-06 2017-01-12 Сименс Акциенгезелльшафт Система и способ введения тепла в геологическую формацию при помощи электромагнитной индукции
CN106916073A (zh) * 2017-01-20 2017-07-04 上海巧坤化工科技有限公司 一种大麦芽碱盐酸盐的合成方法
CN111511745B (zh) * 2018-02-06 2022-05-27 江苏恒瑞医药股份有限公司 吡唑并[1，5-a][1，3，5]三嗪-2-胺类衍生物、其制备方法及其应用
EP3814355A4 (en) * 2018-06-26 2022-06-08 Zhejiang Vimgreen Pharmaceuticals, Ltd PYRAZOLOTRIAZOLOPYRIMIDE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS
KR102613340B1 (ko) * 2018-06-26 2023-12-14 쩌지앙 빔그린 파머슈티컬스, 엘티디 A2a 수용체 길항제로서의 트리아졸로 트리아진 유도체
BE1026602B1 (fr) 2018-09-27 2020-06-18 Iteos Therapeutics S A Inhibiteurs d’a2a ne penetrant pas dans le cerveau et methodes d’utilisation dans le traitement de cancers
WO2020103939A1 (zh) * 2018-11-22 2020-05-28 上海科技大学 ***并环类化合物、其制备方法、中间体和应用
CN112574214B (zh) * 2019-07-30 2021-09-28 杭州阿诺生物医药科技有限公司 腺苷受体拮抗剂的制备方法
JP2023508182A (ja) * 2019-12-26 2023-03-01 チェジン ヴィムグリーン ファーマシューティカルズ リミテッド トリアゾロトリアジン誘導体の疾患治療への応用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846423A (en) * 1972-06-08 1974-11-05 Icn Pharmaceuticals Pyrazolo (1,5a) 1,3,5-triazines
BE815405A (en) * 1973-05-22 1974-11-22 Pyrazolo(1,5-a)-s-triazines - and their salts, with bronchospasmolytic activity
US3995039A (en) * 1975-05-27 1976-11-30 Merck & Co., Inc. Pyrazolo [1,5-a] [1,3,5] triazines
GB1579932A (en) * 1976-05-12 1980-11-26 Ici Ltd Herbicidal triazolotriazines
GB2016002B (en) * 1978-01-09 1982-05-06 Aron Sa Amino derivatives of pyrazolo(1,5-a)s triazine
AU2192683A (en) * 1982-12-30 1984-07-05 Biomeasure Incorporated Pyrazolo(1,5-alpha)-1,3,5-triazines
CA1267143A (en) * 1985-06-06 1990-03-27 Sun H. Kim Anti-arthritic 7-phenylpyrazole[1,5-a]-1,3,5- triazine derivatives
US4824834A (en) * 1986-10-31 1989-04-25 Otsuka Pharmaceutical Company, Limited Pyrazolotriazine compounds
US4734413A (en) * 1987-03-02 1988-03-29 Riker Laboratories, Inc. Substituted 1,2,4-triazolo[1,5-A]triazines as bronchodilators
DE3885357T2 (de) * 1987-06-29 1994-03-24 Duphar Int Res Anellierte Indolderivate.
US4970142A (en) * 1989-02-16 1990-11-13 Konica Corporation Silver halide photographic light-sensitive material containing cyan coupler
GB2244487B (en) * 1990-05-29 1994-02-02 Ici Plc Azole derivatives

Also Published As

Publication number Publication date
GB2244487B (en) 1994-02-02
AU7734891A (en) 1991-12-05
AP248A (en) 1993-03-16
NZ238288A (en) 1993-07-27
IL98316A0 (en) 1992-06-21
NO912051D0 (no) 1991-05-28
NO912051L (no) 1991-12-02
AU642494B2 (en) 1993-10-21
OA09358A (fr) 1992-09-15
NO178401B (no) 1995-12-11
GB2244487A (en) 1991-12-04
FI912563A (fi) 1991-11-30
HU911789D0 (en) 1991-12-30
EP0459702A1 (en) 1991-12-04
JP2504879B2 (ja) 1996-06-05
JPH0597855A (ja) 1993-04-20
US5270311A (en) 1993-12-14
CA2043424A1 (en) 1991-11-30
CN1056879A (zh) 1991-12-11
YU94791A (sh) 1994-06-24
KR910020012A (ko) 1991-12-19
NO178401C (no) 1996-03-20
RO109542B1 (ro) 1995-03-30
GB9111132D0 (en) 1991-07-17
CS159591A3 (en) 1992-01-15
PT97776A (pt) 1992-03-31
FI912563A0 (fi) 1991-05-28
IL98316A (en) 1995-05-26
YU47812B (sr) 1996-01-09
IE911818A1 (en) 1991-12-04
AP9100266A0 (en) 1991-07-31

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Legal Events

Date Code Title Description
DGB9 Succession in title of applicant

Owner name: ZENECA LTD., GB

DFC4 Cancellation of temporary protection due to refusal