HUP9904052A3 - Monoclonal antibodies againts the extracellular domain of human vegf-receptor protein (kdr) - Google Patents
Monoclonal antibodies againts the extracellular domain of human vegf-receptor protein (kdr)Info
- Publication number
- HUP9904052A3 HUP9904052A3 HU9904052A HUP9904052A HUP9904052A3 HU P9904052 A3 HUP9904052 A3 HU P9904052A3 HU 9904052 A HU9904052 A HU 9904052A HU P9904052 A HUP9904052 A HU P9904052A HU P9904052 A3 HUP9904052 A3 HU P9904052A3
- Authority
- HU
- Hungary
- Prior art keywords
- againts
- kdr
- monoclonal antibodies
- extracellular domain
- receptor protein
- Prior art date
Links
- 108091008605 VEGF receptors Proteins 0.000 title 1
- 102000009484 Vascular Endothelial Growth Factor Receptors Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
- A61K51/103—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants against receptors for growth factors or receptors for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19638745A DE19638745C2 (de) | 1996-09-11 | 1996-09-11 | Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR) |
PCT/EP1997/004928 WO1998011223A1 (en) | 1996-09-11 | 1997-09-09 | Monoclonal antibodies against the extracellular domain of human vegf-receptor protein (kdr) |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9904052A2 HUP9904052A2 (hu) | 2000-03-28 |
HUP9904052A3 true HUP9904052A3 (en) | 2002-01-28 |
Family
ID=7806450
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9904052A HUP9904052A3 (en) | 1996-09-11 | 1997-09-09 | Monoclonal antibodies againts the extracellular domain of human vegf-receptor protein (kdr) |
Country Status (12)
Country | Link |
---|---|
US (1) | US6344339B1 (hu) |
EP (1) | EP0925359A1 (hu) |
JP (1) | JP2001501920A (hu) |
AU (1) | AU730287B2 (hu) |
CA (1) | CA2265927A1 (hu) |
DE (1) | DE19638745C2 (hu) |
HU (1) | HUP9904052A3 (hu) |
IL (1) | IL128406A0 (hu) |
NO (1) | NO991162L (hu) |
PL (1) | PL332034A1 (hu) |
WO (1) | WO1998011223A1 (hu) |
ZA (1) | ZA978204B (hu) |
Families Citing this family (94)
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---|---|---|---|---|
AU2299099A (en) * | 1998-02-04 | 1999-08-23 | Kyowa Hakko Kogyo Co. Ltd. | Antibodies against human vegf receptor kdr |
DE19813774A1 (de) * | 1998-03-27 | 1999-09-30 | Max Planck Gesellschaft | Parapockenvirus-kodierter vaskulärer Endothelzell Wachstumsfaktor (PPV-VEGF) |
NO983911D0 (no) * | 1998-08-26 | 1998-08-26 | Norsk Hydro As | Alginatkapsler til bruk ved behandling av hjernesvulst |
PL348163A1 (en) * | 1998-11-06 | 2002-05-06 | Basf Ag | Inhibition of the formation of vascular hyperpermeability |
JP2002536968A (ja) * | 1999-01-29 | 2002-11-05 | イムクローン システムズ インコーポレイティド | Kdrに特異的な抗体およびその使用 |
EP1130032A1 (en) * | 2000-02-28 | 2001-09-05 | Gesellschaft für biotechnologische Forschung mbH (GBF) | Single-chain antibodies recognizing the human vascular endothelial growth factor receptor-2 (VEGFR-2/KDR) |
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Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1173991C (zh) | 1992-11-13 | 2004-11-03 | 马克斯普朗克科学促进协会 | 作为血管内皮生长因子受体的f1k-1 |
US5861499A (en) * | 1994-02-10 | 1999-01-19 | Imclone Systems Incorporated | Nucleic acid molecules encoding the variable or hypervariable region of a monoclonal antibody that binds to an extracellular domain |
US5840301A (en) | 1994-02-10 | 1998-11-24 | Imclone Systems Incorporated | Methods of use of chimerized, humanized, and single chain antibodies specific to VEGF receptors |
-
1996
- 1996-09-11 DE DE19638745A patent/DE19638745C2/de not_active Expired - Fee Related
-
1997
- 1997-09-09 WO PCT/EP1997/004928 patent/WO1998011223A1/en not_active Application Discontinuation
- 1997-09-09 AU AU46222/97A patent/AU730287B2/en not_active Ceased
- 1997-09-09 JP JP10513245A patent/JP2001501920A/ja not_active Ceased
- 1997-09-09 PL PL97332034A patent/PL332034A1/xx unknown
- 1997-09-09 US US09/254,640 patent/US6344339B1/en not_active Expired - Fee Related
- 1997-09-09 CA CA002265927A patent/CA2265927A1/en not_active Abandoned
- 1997-09-09 HU HU9904052A patent/HUP9904052A3/hu unknown
- 1997-09-09 EP EP97944862A patent/EP0925359A1/en not_active Withdrawn
- 1997-09-09 IL IL12840697A patent/IL128406A0/xx unknown
- 1997-09-11 ZA ZA9708204A patent/ZA978204B/xx unknown
-
1999
- 1999-03-10 NO NO991162A patent/NO991162L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2001501920A (ja) | 2001-02-13 |
US6344339B1 (en) | 2002-02-05 |
HUP9904052A2 (hu) | 2000-03-28 |
NO991162L (no) | 1999-05-06 |
DE19638745A1 (de) | 1998-03-12 |
ZA978204B (en) | 1998-03-03 |
IL128406A0 (en) | 2000-01-31 |
DE19638745C2 (de) | 2001-05-10 |
AU730287B2 (en) | 2001-03-01 |
NO991162D0 (no) | 1999-03-10 |
PL332034A1 (en) | 1999-08-16 |
AU4622297A (en) | 1998-04-02 |
EP0925359A1 (en) | 1999-06-30 |
WO1998011223A1 (en) | 1998-03-19 |
CA2265927A1 (en) | 1998-03-19 |
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