HUP9802077A2 - Alendronát alkalmazása csigolyatörések kockázatát csökkentő gyógyszerkészítmény előállítására - Google Patents

Alendronát alkalmazása csigolyatörések kockázatát csökkentő gyógyszerkészítmény előállítására

Info

Publication number
HUP9802077A2
HUP9802077A2 HU9802077A HUP9802077A HUP9802077A2 HU P9802077 A2 HUP9802077 A2 HU P9802077A2 HU 9802077 A HU9802077 A HU 9802077A HU P9802077 A HUP9802077 A HU P9802077A HU P9802077 A2 HUP9802077 A2 HU P9802077A2
Authority
HU
Hungary
Prior art keywords
alendronate
risk
lessening
vertebral fractures
reduction
Prior art date
Application number
HU9802077A
Other languages
English (en)
Inventor
Thomas P. Capizzi
David B. Karpf
Hui Quan
Arthur C. II. Santora
Ashley J. Yates
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Publication of HUP9802077A2 publication Critical patent/HUP9802077A2/hu
Publication of HUP9802077A3 publication Critical patent/HUP9802077A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgya az alendrőnát vagy gyógyászatilag elfőgadhatósóinak alkalmazása az alábbi betegségek kezelésére szőlgálógyógyászati készítmények előállítására. a) menőpaűza űtáni nőknélcsigőlyatörések kőckázatának csökkentése, b) csőnttörést elszenvedettbetegnél a csőnttörés következményeinek csökkentése, c)ősteőpőrősisban szenvedő nőknél gerincdefőrmitás csökkentése, d)ősteőpőrősis-szenvedő nőknél csőnttömegveszteség megelőzése. ŕ
HU9802077A 1995-02-17 1996-02-13 Use of alendronate for preparing medicament useful for lessening the risk of vertebral fractures HUP9802077A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/389,860 US20010051616A1 (en) 1995-02-17 1995-02-17 Method of lessening the risk of vertebral fractures
PCT/US1996/001946 WO1996025166A1 (en) 1995-02-17 1996-02-13 Method of lessening the risk of vertebral fractures

Publications (2)

Publication Number Publication Date
HUP9802077A2 true HUP9802077A2 (hu) 2000-06-28
HUP9802077A3 HUP9802077A3 (en) 2001-10-29

Family

ID=23540050

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9802077A HUP9802077A3 (en) 1995-02-17 1996-02-13 Use of alendronate for preparing medicament useful for lessening the risk of vertebral fractures

Country Status (14)

Country Link
US (1) US20010051616A1 (hu)
EP (1) EP0809503A4 (hu)
JP (1) JPH11501906A (hu)
KR (1) KR19980702209A (hu)
CN (1) CN1181008A (hu)
AU (1) AU689379B2 (hu)
CA (1) CA2213076A1 (hu)
EA (1) EA000348B1 (hu)
HU (1) HUP9802077A3 (hu)
NZ (1) NZ303476A (hu)
PL (1) PL321836A1 (hu)
SK (1) SK111697A3 (hu)
WO (1) WO1996025166A1 (hu)
ZA (1) ZA961234B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6432932B1 (en) 1997-07-22 2002-08-13 Merck & Co., Inc. Method for inhibiting bone resorption
US5994329A (en) 1997-07-22 1999-11-30 Merck & Co., Inc. Method for inhibiting bone resorption
AU1525700A (en) * 1998-11-19 2000-06-05 Board Of Trustees Of The University Of Arkansas, The Increasing bone strength with selected bisphosphonates
KR100317935B1 (ko) * 1999-10-20 2001-12-22 유승필 대사성 골질환 치료용 약제조성물 및 이의 제조방법
MXPA04006027A (es) * 2001-12-21 2004-09-27 Procter & Gamble Metodo para el tratamiento de trastornos de los huesos.
US20040052843A1 (en) * 2001-12-24 2004-03-18 Lerner E. Itzhak Controlled release dosage forms
EP2172192A1 (en) * 2001-12-24 2010-04-07 Teva Pharmaceutical Industries Ltd. Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder of granular material, and process and tooling for producing it
KR20140021045A (ko) * 2002-05-10 2014-02-19 에프. 호프만-라 로슈 아게 골다공증 치료 및 예방용 비스포스폰산
JP4427453B2 (ja) 2002-12-20 2010-03-10 エフ．ホフマン−ラ ロシュ アーゲー 高用量イバンドロネート製剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche
US4761406A (en) * 1985-06-06 1988-08-02 The Procter & Gamble Company Regimen for treating osteoporosis
EP0600834A1 (en) * 1992-11-30 1994-06-08 Ciba-Geigy Ag Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery

Also Published As

Publication number Publication date
JPH11501906A (ja) 1999-02-16
AU689379B2 (en) 1998-03-26
EP0809503A1 (en) 1997-12-03
KR19980702209A (ko) 1998-07-15
MX9706275A (es) 1997-11-29
CN1181008A (zh) 1998-05-06
PL321836A1 (en) 1997-12-22
EA000348B1 (ru) 1999-04-29
SK111697A3 (en) 1998-02-04
CA2213076A1 (en) 1996-08-22
EP0809503A4 (en) 2001-12-05
HUP9802077A3 (en) 2001-10-29
NZ303476A (en) 2000-07-28
ZA961234B (en) 1996-08-27
EA199700185A1 (ru) 1997-12-30
AU4979996A (en) 1996-09-04
US20010051616A1 (en) 2001-12-13
WO1996025166A1 (en) 1996-08-22

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