HUP9801686A2 - Amino-tetralin-származék alkalmazása kardiovaszkuláris megbetegedések terápiájában használható gyógyszer előállítására - Google Patents

Amino-tetralin-származék alkalmazása kardiovaszkuláris megbetegedések terápiájában használható gyógyszer előállítására

Info

Publication number
HUP9801686A2
HUP9801686A2 HU9801686A HUP9801686A HUP9801686A2 HU P9801686 A2 HUP9801686 A2 HU P9801686A2 HU 9801686 A HU9801686 A HU 9801686A HU P9801686 A HUP9801686 A HU P9801686A HU P9801686 A2 HUP9801686 A2 HU P9801686A2
Authority
HU
Hungary
Prior art keywords
therapy
cardiovascular diseases
producing pharmaceutical
aminotetralin derivative
aminotetralin
Prior art date
Application number
HU9801686A
Other languages
English (en)
Inventor
Stefano Bongrani
Paolo Chiesi
Maurizio Civelli
Roberta Razetti
Alberto Umile
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of HUP9801686A2 publication Critical patent/HUP9801686A2/hu
Publication of HUP9801686A3 publication Critical patent/HUP9801686A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A találmány tárgya 5,6-di(izőbűtirőil-őxi)-2-(metil-aminő)-tetralin(CHF 1035 jelű vegyület) alkalmazása szívbetegségek, különösenpangásős szívelégtelenség terápiájában felhasználható gyógyászatikészítmények előállításában. ŕ
HU9801686A 1995-03-17 1996-03-13 Use of aminotetralin derivative for producing pharmaceutical for the therapy of cardiovascular diseases HUP9801686A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI000532A IT1275935B1 (it) 1995-03-17 1995-03-17 Derivato di aminotetralina per la terapia di malattie cardiovascolari

Publications (2)

Publication Number Publication Date
HUP9801686A2 true HUP9801686A2 (hu) 1999-06-28
HUP9801686A3 HUP9801686A3 (en) 1999-10-28

Family

ID=11370947

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801686A HUP9801686A3 (en) 1995-03-17 1996-03-13 Use of aminotetralin derivative for producing pharmaceutical for the therapy of cardiovascular diseases

Country Status (31)

Country Link
US (2) US6013678A (hu)
EP (2) EP0814791B1 (hu)
JP (1) JPH11502211A (hu)
KR (1) KR100391143B1 (hu)
CN (1) CN1112920C (hu)
AT (1) ATE218856T1 (hu)
AU (1) AU702656B2 (hu)
BR (1) BR9607996A (hu)
CA (1) CA2215671A1 (hu)
CZ (1) CZ288488B6 (hu)
DE (1) DE69621786T2 (hu)
DK (1) DK0814791T3 (hu)
EA (1) EA000937B1 (hu)
EE (1) EE04040B1 (hu)
ES (1) ES2177769T3 (hu)
HK (2) HK1004802A1 (hu)
HU (1) HUP9801686A3 (hu)
IL (1) IL117518A (hu)
IT (1) IT1275935B1 (hu)
LT (1) LT4355B (hu)
LV (1) LV11882B (hu)
MX (1) MX9706971A (hu)
NO (1) NO317402B1 (hu)
NZ (1) NZ303993A (hu)
PL (1) PL183347B1 (hu)
PT (1) PT814791E (hu)
SI (1) SI9620036B (hu)
SK (1) SK282952B6 (hu)
TR (1) TR199700963T1 (hu)
WO (1) WO1996029065A2 (hu)
ZA (1) ZA962073B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2695157B2 (ja) * 1986-12-29 1997-12-24 松下電器産業株式会社 可変パイプラインプロセッサ
WO2000076544A1 (en) * 1996-03-13 2000-12-21 Chiesi Farmaceutici S.P.A. Aminotetralin derivative for the therapy of cardiovascular diseases
EP1331004A3 (en) * 1999-06-09 2003-08-06 CHIESI FARMACEUTICI S.p.A. Aminotetralin Derivative for the Therapy of Cardiovascular Diseases
AU766230B2 (en) * 1999-06-09 2003-10-09 Chiesi Farmaceutici S.P.A. Aminotetralin derivative for the therapy of cardiovascular diseases
IT1313583B1 (it) * 1999-07-30 2002-09-09 Chiesi Farma Spa Derivati 2-amminotetralinici per la terapia del glaucoma.
IL152751A0 (en) * 2000-05-12 2003-06-24 Chiesi Farma Spa Optically active 2-aminotetralin derivatives, the processes for the preparation thereof and the therapeutical use of pharmaceutical compositions containing them
SE0101854L (sv) * 2001-05-28 2002-11-29 Bioneris Ab Användning av en förening med en negativt laddad region av grupper för behandling av restenos.
EP1384708A1 (en) * 2002-07-26 2004-01-28 CHIESI FARMACEUTICI S.p.A. Process for the manufacture of form I of nolomirole hydrochloride
US20050101668A1 (en) * 2003-07-24 2005-05-12 Chiesi Farmaceutici S.P.A. Aminotetralin derivatives as a medicament for the treatment and prevention of myocardial ischemic conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4134997A (en) * 1977-03-01 1979-01-16 University Of Iowa Research Foundation Effect of an aminotetralin derivative on coronary blood flow in infarcted hearts
SU998342A1 (ru) 1981-12-11 1983-02-23 Предприятие П/Я А-3732 Способ получени синтетического цеолита типа @
IT1218322B (it) * 1982-06-10 1990-04-12 Chiesi Farma Spa Derivati di 1,2,3,4-tetraidronaftalene,procedimento di preparazione e relative composizioni farmaceutiche

Also Published As

Publication number Publication date
JPH11502211A (ja) 1999-02-23
AU5107296A (en) 1996-10-08
PT814791E (pt) 2002-10-31
LV11882B (en) 1998-03-20
DK0814791T3 (da) 2002-10-07
SK125497A3 (en) 1998-02-04
MX9706971A (es) 1997-11-29
SI9620036A (sl) 1998-02-28
EE9700231A (et) 1998-04-15
PL183347B1 (pl) 2002-06-28
NO317402B1 (no) 2004-10-25
KR100391143B1 (ko) 2003-11-28
IT1275935B1 (it) 1997-10-24
CZ286697A3 (cs) 1998-03-18
CN1181699A (zh) 1998-05-13
LT4355B (lt) 1998-06-25
HK1004802A1 (en) 1998-12-11
ES2177769T3 (es) 2002-12-16
CN1112920C (zh) 2003-07-02
AU702656B2 (en) 1999-02-25
NZ303993A (en) 2000-12-22
US6103760A (en) 2000-08-15
HK1048060A1 (zh) 2003-03-21
LT97147A (en) 1998-02-25
EP0814791B1 (en) 2002-06-12
EP1216702A2 (en) 2002-06-26
EP0814791A1 (en) 1998-01-07
TR199700963T1 (xx) 1998-02-21
EP1216702A3 (en) 2002-09-04
ATE218856T1 (de) 2002-06-15
CZ288488B6 (en) 2001-06-13
ZA962073B (en) 1996-11-27
NO974267L (no) 1997-11-07
LV11882A (lv) 1997-12-20
ITMI950532A1 (it) 1996-09-17
US6013678A (en) 2000-01-11
ITMI950532A0 (it) 1995-03-17
SI9620036B (sl) 2002-10-31
HUP9801686A3 (en) 1999-10-28
WO1996029065A2 (en) 1996-09-26
SK282952B6 (sk) 2003-01-09
EE04040B1 (et) 2003-06-16
EA199700243A1 (ru) 1998-02-26
CA2215671A1 (en) 1996-09-26
NO974267D0 (no) 1997-09-16
EA000937B1 (ru) 2000-06-26
WO1996029065A3 (en) 1996-11-28
KR19980703030A (ko) 1998-09-05
BR9607996A (pt) 1998-06-23
DE69621786D1 (de) 2002-07-18
IL117518A0 (en) 1996-07-23
IL117518A (en) 2001-05-20
PL322284A1 (en) 1998-01-19
DE69621786T2 (de) 2003-01-02

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