HUE046795T2 - Új vírusellenes pirrolopiridin származékok és eljárás azok elõállítására - Google Patents
Új vírusellenes pirrolopiridin származékok és eljárás azok elõállításáraInfo
- Publication number
- HUE046795T2 HUE046795T2 HUE12849140A HUE12849140A HUE046795T2 HU E046795 T2 HUE046795 T2 HU E046795T2 HU E12849140 A HUE12849140 A HU E12849140A HU E12849140 A HUE12849140 A HU E12849140A HU E046795 T2 HUE046795 T2 HU E046795T2
- Authority
- HU
- Hungary
- Prior art keywords
- same
- production method
- novel antiviral
- pyrrolopyridine derivative
- pyrrolopyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20110119102 | 2011-11-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE046795T2 true HUE046795T2 (hu) | 2020-03-30 |
Family
ID=48429876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE12849140A HUE046795T2 (hu) | 2011-11-15 | 2012-11-15 | Új vírusellenes pirrolopiridin származékok és eljárás azok elõállítására |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9499537B2 (hu) |
| EP (1) | EP2781519B1 (hu) |
| JP (1) | JP5893156B2 (hu) |
| KR (1) | KR101467477B1 (hu) |
| CN (1) | CN104066732B (hu) |
| DK (1) | DK2781519T3 (hu) |
| ES (1) | ES2760981T3 (hu) |
| HU (1) | HUE046795T2 (hu) |
| PL (1) | PL2781519T3 (hu) |
| PT (1) | PT2781519T (hu) |
| WO (1) | WO2013073875A1 (hu) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9163023B2 (en) | 2012-07-12 | 2015-10-20 | Viiv Healthcare Uk Limited | Compounds and methods for treating HIV |
| TW201441197A (zh) | 2013-01-31 | 2014-11-01 | Shionogi & Co | Ｈｉｖ複製抑制劑 |
| EP2821082A1 (en) | 2013-07-05 | 2015-01-07 | Laboratoire Biodim | Method of producing an inactivated lentivirus, especially HIV, vaccine, kit and method of use |
| PT3105236T (pt) | 2014-02-12 | 2017-12-22 | Viiv Healthcare Uk (No 5) Ltd | Macrociclos de benzotiazole como inibidores da replicação do vírus da imunodeficiência humana |
| US9932353B2 (en) | 2014-02-18 | 2018-04-03 | Viiv Healthcare Uk (No. 5) Limited | Imidazopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| US9409922B2 (en) | 2014-02-18 | 2016-08-09 | Bristol-Myers Squibb Company | Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication |
| WO2015126743A1 (en) | 2014-02-18 | 2015-08-27 | Bristol-Myers Squibb Company | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| US9273067B2 (en) | 2014-02-19 | 2016-03-01 | Bristol-Myers Squibb Company | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| EP3144311A4 (en) | 2014-05-16 | 2018-01-03 | Shionogi & Co., Ltd. | Tricyclic heterocyclic derivative having hiv replication-inhibiting effect |
| KR101592370B1 (ko) * | 2014-06-09 | 2016-02-11 | 한국화학연구원 | 신규한 피롤로피리딘 유도체 및 이의 hiv 저해제로서의 용도 |
| CN104478911A (zh) * | 2014-12-19 | 2015-04-01 | 成都安斯利生物医药有限公司 | 一种制备3-三氟甲基吡咯硼酸的方法 |
| KR20180011267A (ko) | 2015-05-29 | 2018-01-31 | 시오노기 앤드 컴파니, 리미티드 | Hiv 복제 저해 작용을 갖는 함질소 3환성 유도체 |
| MX2019011220A (es) * | 2017-03-24 | 2019-11-01 | St Pharm Co Ltd | Compuesto de pirrolopiridina novedoso, metodo de preparacion del mismo y uso del mismo. |
| KR20200012833A (ko) | 2017-03-29 | 2020-02-05 | 사이트원 테라퓨틱스, 인코포레이티드 | 통증 치료용 11,13-개질된 색시톡신 |
| JP7096686B2 (ja) * | 2017-03-30 | 2022-07-06 | 住友化学株式会社 | アミノ基を有する有機リチウム化合物およびその中間体の製造方法、並びに有機リチウム化合物を用いた共役ジエン系重合体の製造方法 |
| MX2022008091A (es) | 2020-01-10 | 2022-07-11 | Jiangsu Hengrui Medicine Co | Derivado de tetrahidroisoquinolina triciclica, metodo de preparacion del mismo y aplicacion del mismo en medicina. |
| KR20220023187A (ko) * | 2020-08-20 | 2022-03-02 | 에스티팜 주식회사 | 피롤로피리딘 유도체 및 이들의 용도 |
| JP2024502364A (ja) | 2021-01-11 | 2024-01-18 | エスティ ファーム カンパニー リミテッド | ピロロピリジン誘導体の製造方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0510319A (pt) * | 2004-04-26 | 2007-10-16 | Pfizer | inibidores da enzima integrase de hiv |
| DE102004060659A1 (de) * | 2004-12-15 | 2006-07-06 | Lanxess Deutschland Gmbh | Neue substituierte 1H-Pyrrolo[2,3-b]pyridine und deren Herstellung |
| US7939545B2 (en) * | 2006-05-16 | 2011-05-10 | Boehringer Ingelheim International Gmbh | Inhibitors of human immunodeficiency virus replication |
| GB0710528D0 (en) * | 2007-06-01 | 2007-07-11 | Glaxo Group Ltd | Novel compounds |
| KR20100108337A (ko) * | 2007-11-15 | 2010-10-06 | 베링거 인겔하임 인터내셔날 게엠베하 | 사람 면역결핍 바이러스 복제의 억제제 |
| EP2757096A1 (en) * | 2007-11-16 | 2014-07-23 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| EP2220084B1 (en) * | 2007-11-16 | 2014-02-19 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| US8338441B2 (en) * | 2009-05-15 | 2012-12-25 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| GB0908394D0 (en) * | 2009-05-15 | 2009-06-24 | Univ Leuven Kath | Novel viral replication inhibitors |
| AU2012209373A1 (en) * | 2011-01-24 | 2013-04-11 | Glaxosmithkline Llc | Isoquinoline compounds and methods for treating HIV |
| WO2013012649A1 (en) * | 2011-07-15 | 2013-01-24 | Glaxosmithkline Llc | Azaindole compounds and methods for treating hiv |
-
2012
- 2012-11-15 ES ES12849140T patent/ES2760981T3/es active Active
- 2012-11-15 JP JP2014542241A patent/JP5893156B2/ja active Active
- 2012-11-15 DK DK12849140.4T patent/DK2781519T3/da active
- 2012-11-15 WO PCT/KR2012/009689 patent/WO2013073875A1/ko active Application Filing
- 2012-11-15 KR KR1020120129805A patent/KR101467477B1/ko active IP Right Grant
- 2012-11-15 PL PL12849140T patent/PL2781519T3/pl unknown
- 2012-11-15 CN CN201280066270.1A patent/CN104066732B/zh active Active
- 2012-11-15 HU HUE12849140A patent/HUE046795T2/hu unknown
- 2012-11-15 EP EP12849140.4A patent/EP2781519B1/en active Active
- 2012-11-15 PT PT128491404T patent/PT2781519T/pt unknown
-
2014
- 2014-05-15 US US14/278,955 patent/US9499537B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR20130054211A (ko) | 2013-05-24 |
| PT2781519T (pt) | 2019-12-17 |
| PL2781519T3 (pl) | 2020-06-29 |
| JP2014533298A (ja) | 2014-12-11 |
| DK2781519T3 (da) | 2019-12-16 |
| US20140249162A1 (en) | 2014-09-04 |
| CN104066732A (zh) | 2014-09-24 |
| EP2781519A1 (en) | 2014-09-24 |
| US9499537B2 (en) | 2016-11-22 |
| JP5893156B2 (ja) | 2016-03-23 |
| KR101467477B1 (ko) | 2014-12-02 |
| CN104066732B (zh) | 2016-04-13 |
| EP2781519A4 (en) | 2015-06-24 |
| ES2760981T3 (es) | 2020-05-18 |
| EP2781519B1 (en) | 2019-10-30 |
| WO2013073875A1 (ko) | 2013-05-23 |
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