HU226194B1 - Humán szolubilis LDL-receptorra specifikus monoklonális ellenanyagok, elõállításuk és alkalmazásuk - Google Patents

Humán szolubilis LDL-receptorra specifikus monoklonális ellenanyagok, elõállításuk és alkalmazásuk Download PDF

Info

Publication number: HU226194B1
Authority: HU; Hungary
Prior art keywords: monoclonal antibody; ldlr; antibody; human; deposited
Prior art date: 2000-03-13

Application number

HU0300142A

Other languages

English (en)

Hungarian (hu)

Inventor

Nachum Yonah

Dany Suissa

Ilana Belzer

Francesco Antonetti

Moshe Smolarsky

Michel Dreano

Original Assignee

Serono Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-13

Filing date

2001-03-08

Publication date

2008-06-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26323933&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU226194(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-03-13 Priority claimed from IL13502500A external-priority patent/IL135025A0/xx

2001-03-08 Application filed by Serono Lab filed Critical Serono Lab

2003-06-28 Publication of HUP0300142A2 publication Critical patent/HUP0300142A2/hu

2005-07-28 Publication of HUP0300142A3 publication Critical patent/HUP0300142A3/hu

2008-06-30 Publication of HU226194B1 publication Critical patent/HU226194B1/hu

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/82—Hepatitis associated antigens and antibodies

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Virology (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

HU0300142A 2000-03-13 2001-03-08 Humán szolubilis LDL-receptorra specifikus monoklonális ellenanyagok, elõállításuk és alkalmazásuk HU226194B1 (hu)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IL13502500A IL135025A0 (en)	2000-03-13	2000-03-13	Monoclonal antibodies to the human ldl receptor, their production and use
IL13921700A IL139217A0 (en)	2000-03-13	2000-10-23	Monoclonal antibodies to the human ldl receptor, their production and use
PCT/IL2001/000216 WO2001068710A1 (en)	2000-03-13	2001-03-08	Monoclonal antibodies to the human ldl receptor, their production and use

Publications (3)

Publication Number	Publication Date
HUP0300142A2 HUP0300142A2 (hu)	2003-06-28
HUP0300142A3 HUP0300142A3 (en)	2005-07-28
HU226194B1 true HU226194B1 (hu)	2008-06-30

Family

ID=26323933

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0300142A HU226194B1 (hu)	2000-03-13	2001-03-08	Humán szolubilis LDL-receptorra specifikus monoklonális ellenanyagok, elõállításuk és alkalmazásuk

Country Status (33)

Country	Link
US (1)	US6849720B2 (sh)
EP (1)	EP1263790B1 (sh)
JP (1)	JP4768193B2 (sh)
KR (1)	KR100882081B1 (sh)
CN (1)	CN1418225B (sh)
AR (1)	AR028518A1 (sh)
AT (1)	ATE362490T1 (sh)
AU (2)	AU4100201A (sh)
BG (1)	BG65762B1 (sh)
BR (1)	BR0109164A (sh)
CA (1)	CA2402593C (sh)
CY (1)	CY1108020T1 (sh)
CZ (1)	CZ20023098A3 (sh)
DE (1)	DE60128452T2 (sh)
DK (1)	DK1263790T3 (sh)
EA (1)	EA007494B1 (sh)
EE (1)	EE200200517A (sh)
ES (1)	ES2282238T3 (sh)
HK (1)	HK1055750A1 (sh)
HR (1)	HRP20020704B1 (sh)
HU (1)	HU226194B1 (sh)
IL (2)	IL139217A0 (sh)
MX (1)	MXPA02009091A (sh)
NO (1)	NO330904B1 (sh)
NZ (1)	NZ520944A (sh)
PL (1)	PL206041B1 (sh)
PT (1)	PT1263790E (sh)
RS (1)	RS51406B (sh)
SI (1)	SI1263790T1 (sh)
SK (1)	SK287348B6 (sh)
UA (1)	UA78489C2 (sh)
WO (1)	WO2001068710A1 (sh)
ZA (1)	ZA200206654B (sh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0114629D0 (en) *	2001-06-15	2001-08-08	Pfizer Ltd	Method
US7598046B2 (en)	2003-06-19	2009-10-06	Laboratories Serono Sa	Use of prion conversion modulating agents
FR2889532B1 (fr) *	2005-08-03	2007-10-12	Lab Francais Du Fractionnement	Anticorps diriges contre le recepteur du ldl
FR2889533B1 (fr) *	2005-08-03	2007-10-12	Lab Francais Du Fractionnement	Anticorps diriges contre le recepteur du ldl
EP1991869A2 (en) *	2006-02-17	2008-11-19	Paolo La Colla	Methods for the diagnosis of proliferative and/or conformational diseases
FR2910896B1 (fr) *	2006-12-29	2012-11-16	Lab Francais Du Fractionnement	Anticorps monoclonal dirige contre le recepteur humain des ldl
IL182956A0 (en)	2007-05-03	2008-01-20	Yeda Res & Dev	Glycan modified soluble receptors and binding proteins and their use
IL188628A0 (en) *	2008-01-07	2008-12-29	Yeda Res & Dev	Use of soluble ldl-r for viral hepatitis
GB0922377D0 (en) *	2009-12-22	2010-02-03	Arab Gulf University The	Mutant LDL receptor
BR112012029881A2 (pt)	2010-05-25	2019-09-24	Inserm (Institut National De La Santé De La Recherche Médicale)	combinação de anticorpos anti-envelope e anticorpos anti-receptor para o tratamento e a presenção de infecção por hcv
WO2013024155A1 (en)	2011-08-17	2013-02-21	Inserm (Institut National De La Sante Et De La Recherche Medicale)	Combinations of anti-hcv-entry factor antibodies and direct acting antivirals for the treatment and the prevention of hcv infection
WO2013024157A2 (en)	2011-08-17	2013-02-21	INSERM (Institut National de la Santé et de la Recherche Médicale)	Combinations of host targeting agents for the treatment and the prevention of hcv infection
WO2013024156A2 (en)	2011-08-17	2013-02-21	INSERM (Institut National de la Santé et de la Recherche Médicale)	Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
CN103111270B (zh) *	2013-02-26	2015-06-10	王业富	一种乙型肝炎抗原蛋白的吸附材料及其制备方法

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Publication number	Priority date	Publication date	Assignee	Title
US5182364A (en) *	1990-02-26	1993-01-26	The Scripps Research Institute	Polypeptide analogs of apolipoprotein E
US5496926A (en) *	1992-01-19	1996-03-05	Yeda Research And Development Co. Ltd.	Process of preparing a soluble LDL receptor
US5945308A (en) *	1998-04-03	1999-08-31	Incyte Pharmaceuticals, Inc.	Human oxidized LDL receptor
JP2000279174A (ja) *	1999-03-30	2000-10-10	Bml Inc	ヒトｌｄｌレセプターに対するモノクローナル抗体及びこれを用いる家族性高脂血症の判定方法

2000
- 2000-10-23 IL IL13921700A patent/IL139217A0/xx unknown
2001
- 2001-03-08 AT AT01912086T patent/ATE362490T1/de active
- 2001-03-08 WO PCT/IL2001/000216 patent/WO2001068710A1/en active IP Right Grant
- 2001-03-08 DE DE60128452T patent/DE60128452T2/de not_active Expired - Lifetime
- 2001-03-08 US US10/221,679 patent/US6849720B2/en not_active Expired - Fee Related
- 2001-03-08 HU HU0300142A patent/HU226194B1/hu not_active IP Right Cessation
- 2001-03-08 CZ CZ20023098A patent/CZ20023098A3/cs unknown
- 2001-03-08 AU AU4100201A patent/AU4100201A/xx active Pending
- 2001-03-08 RS YUP-686/02A patent/RS51406B/sr unknown
- 2001-03-08 EP EP01912086A patent/EP1263790B1/en not_active Expired - Lifetime
- 2001-03-08 KR KR1020027011767A patent/KR100882081B1/ko not_active IP Right Cessation
- 2001-03-08 IL IL15171301A patent/IL151713A0/xx not_active IP Right Cessation
- 2001-03-08 PL PL358381A patent/PL206041B1/pl unknown
- 2001-03-08 PT PT01912086T patent/PT1263790E/pt unknown
- 2001-03-08 JP JP2001567800A patent/JP4768193B2/ja not_active Expired - Fee Related
- 2001-03-08 EE EEP200200517A patent/EE200200517A/xx unknown
- 2001-03-08 AU AU2001241002A patent/AU2001241002B8/en not_active Ceased
- 2001-03-08 CN CN018065740A patent/CN1418225B/zh not_active Expired - Fee Related
- 2001-03-08 MX MXPA02009091A patent/MXPA02009091A/es active IP Right Grant
- 2001-03-08 ES ES01912086T patent/ES2282238T3/es not_active Expired - Lifetime
- 2001-03-08 CA CA2402593A patent/CA2402593C/en not_active Expired - Fee Related
- 2001-03-08 SI SI200130736T patent/SI1263790T1/sl unknown
- 2001-03-08 NZ NZ520944A patent/NZ520944A/en not_active IP Right Cessation
- 2001-03-08 BR BR0109164-6A patent/BR0109164A/pt not_active Application Discontinuation
- 2001-03-08 SK SK1312-2002A patent/SK287348B6/sk not_active IP Right Cessation
- 2001-03-08 DK DK01912086T patent/DK1263790T3/da active
- 2001-03-08 EA EA200200974A patent/EA007494B1/ru not_active IP Right Cessation
- 2001-03-12 AR ARP010101148A patent/AR028518A1/es active IP Right Grant
- 2001-08-03 UA UA2002108101A patent/UA78489C2/uk unknown
2002
- 2002-08-20 ZA ZA200206654A patent/ZA200206654B/en unknown
- 2002-08-28 HR HR20020704A patent/HRP20020704B1/xx not_active IP Right Cessation
- 2002-09-04 NO NO20024223A patent/NO330904B1/no not_active IP Right Cessation
- 2002-09-05 BG BG107063A patent/BG65762B1/bg unknown
2003
- 2003-11-11 HK HK03108147.2A patent/HK1055750A1/xx not_active IP Right Cessation
2007
- 2007-07-13 CY CY20071100939T patent/CY1108020T1/el unknown

Also Published As

Publication number	Publication date
HUP0300142A2 (hu)	2003-06-28
PL206041B1 (pl)	2010-06-30
DK1263790T3 (da)	2007-07-02
YU68602A (sh)	2006-03-03
RS51406B (sr)	2011-02-28
AR028518A1 (es)	2003-05-14
ZA200206654B (en)	2003-10-20
NO330904B1 (no)	2011-08-15
KR100882081B1 (ko)	2009-02-10
ES2282238T3 (es)	2007-10-16
ATE362490T1 (de)	2007-06-15
BG107063A (bg)	2003-05-30
AU4100201A (en)	2001-09-24
NO20024223D0 (no)	2002-09-04
UA78489C2 (en)	2007-04-10
HK1055750A1 (en)	2004-01-21
NO20024223L (no)	2002-10-24
JP4768193B2 (ja)	2011-09-07
CA2402593C (en)	2012-07-03
SK13122002A3 (sk)	2003-04-01
EA200200974A1 (ru)	2003-02-27
WO2001068710A1 (en)	2001-09-20
BG65762B1 (bg)	2009-10-30
EE200200517A (et)	2004-02-16
IL151713A0 (en)	2003-04-10
CA2402593A1 (en)	2001-09-20
NZ520944A (en)	2004-04-30
US20030186343A1 (en)	2003-10-02
KR20020089384A (ko)	2002-11-29
CN1418225B (zh)	2012-04-18
EA007494B1 (ru)	2006-10-27
BR0109164A (pt)	2002-11-26
AU2001241002B8 (en)	2006-05-04
SI1263790T1 (sl)	2007-10-31
MXPA02009091A (es)	2005-06-20
JP2004506603A (ja)	2004-03-04
DE60128452D1 (de)	2007-06-28
IL139217A0 (en)	2001-11-25
HRP20020704A2 (en)	2004-12-31
PL358381A1 (en)	2004-08-09
CY1108020T1 (el)	2013-09-04
US6849720B2 (en)	2005-02-01
SK287348B6 (sk)	2010-08-09
CZ20023098A3 (cs)	2003-02-12
HRP20020704B1 (en)	2011-01-31
DE60128452T2 (de)	2007-09-13
CN1418225A (zh)	2003-05-14
EP1263790A1 (en)	2002-12-11
EP1263790B1 (en)	2007-05-16
AU2001241002B2 (en)	2006-04-06
PT1263790E (pt)	2007-06-01
HUP0300142A3 (en)	2005-07-28

Legal Events

Date	Code	Title	Description
2016-12-28	MM4A	Lapse of definitive patent protection due to non-payment of fees

Publication	Publication Date	Title
US7541438B2 (en)	2009-06-02	Monoclonal antibody against connective tissue growth factor and medicinal uses thereof
JP3746790B2 (ja)	2006-02-15	抗ヒトＶＥＧＦ受容体Ｆ１ｔ―１モノクローナル抗体
US5565354A (en)	1996-10-15	Production of human monoclonal antibodies specific for hepatitis B surface antigen
EP1263790B1 (en)	2007-05-16	Monoclonal antibodies to the human ldl receptor, their production and use
AU2001241002A1 (en)	2001-12-06	Monoclonal antibodies to the human LDL receptor, their production and use
KR100244573B1 (ko)	2000-02-15	사람 유래 씨이티피에 반응성을 갖은 모노클로날 항체 및 사람 유래 씨이티피의 정량방법
AU684455B2 (en)	1997-12-18	Production of human monoclonal antibodies active against hepatitis B surface antigen
JPH05292994A (ja)	1993-11-09	新規キメラ抗イディオタイプモノクローナル抗体
JP3580948B2 (ja)	2004-10-27	ヒト由来ｃｅｔｐに反応性を有するモノクローナル抗体及びヒト由来ｃｅｔｐの定量方法
JPH05276988A (ja)	1993-10-26	新規抗ｈｉｖ抗体
EP0672120B1 (en)	2001-10-17	Production of human monoclonal antibodies active against hepatitis b surface antigen
WO1999006555A1 (fr)	1999-02-11	Nouvelle proteine humaine mmp-20 et son utilisation
JPH1121300A (ja)	1999-01-26	抗ヒトトランスフェリンモノクローナル抗体及びこれを産生するハイブリドーマ細胞株