EA200200974A1 - Моноклональные антитела к рецептору лпнп человека, их получение и применение - Google Patents

Моноклональные антитела к рецептору лпнп человека, их получение и применение

Info

Publication number
EA200200974A1
EA200200974A1 EA200200974A EA200200974A EA200200974A1 EA 200200974 A1 EA200200974 A1 EA 200200974A1 EA 200200974 A EA200200974 A EA 200200974A EA 200200974 A EA200200974 A EA 200200974A EA 200200974 A1 EA200200974 A1 EA 200200974A1
Authority
EA
Eurasian Patent Office
Prior art keywords
monoclonal antibodies
application
receiving
ldl receptor
human ldl
Prior art date
Application number
EA200200974A
Other languages
English (en)
Other versions
EA007494B1 (ru
Inventor
Начум Йонах
Дани Суисса
Илана Бельзер
Франческо Антонетти
Моше Смоларски
Мишель Дреано
Original Assignee
Апплайд Резеч Системз Арс Холдинг Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26323933&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200200974(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from IL13502500A external-priority patent/IL135025A0/xx
Application filed by Апплайд Резеч Системз Арс Холдинг Н.В. filed Critical Апплайд Резеч Системз Арс Холдинг Н.В.
Publication of EA200200974A1 publication Critical patent/EA200200974A1/ru
Publication of EA007494B1 publication Critical patent/EA007494B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/82—Hepatitis associated antigens and antibodies

Abstract

Представлены моноклональные антитела к рецептору ЛПНП человека, которые применимы для идентификации и очистки ЛПНП и для лечения, например, гепатита С.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200200974A 2000-03-13 2001-03-08 Моноклональные антитела к растворимому рецептору лпнп человека, способы их получения и применения и гибридомы, продуцирующие указанные антитела EA007494B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL13502500A IL135025A0 (en) 2000-03-13 2000-03-13 Monoclonal antibodies to the human ldl receptor, their production and use
IL13921700A IL139217A0 (en) 2000-03-13 2000-10-23 Monoclonal antibodies to the human ldl receptor, their production and use
PCT/IL2001/000216 WO2001068710A1 (en) 2000-03-13 2001-03-08 Monoclonal antibodies to the human ldl receptor, their production and use

Publications (2)

Publication Number Publication Date
EA200200974A1 true EA200200974A1 (ru) 2003-02-27
EA007494B1 EA007494B1 (ru) 2006-10-27

Family

ID=26323933

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200974A EA007494B1 (ru) 2000-03-13 2001-03-08 Моноклональные антитела к растворимому рецептору лпнп человека, способы их получения и применения и гибридомы, продуцирующие указанные антитела

Country Status (33)

Country Link
US (1) US6849720B2 (ru)
EP (1) EP1263790B1 (ru)
JP (1) JP4768193B2 (ru)
KR (1) KR100882081B1 (ru)
CN (1) CN1418225B (ru)
AR (1) AR028518A1 (ru)
AT (1) ATE362490T1 (ru)
AU (2) AU4100201A (ru)
BG (1) BG65762B1 (ru)
BR (1) BR0109164A (ru)
CA (1) CA2402593C (ru)
CY (1) CY1108020T1 (ru)
CZ (1) CZ20023098A3 (ru)
DE (1) DE60128452T2 (ru)
DK (1) DK1263790T3 (ru)
EA (1) EA007494B1 (ru)
EE (1) EE200200517A (ru)
ES (1) ES2282238T3 (ru)
HK (1) HK1055750A1 (ru)
HR (1) HRP20020704B1 (ru)
HU (1) HU226194B1 (ru)
IL (2) IL139217A0 (ru)
MX (1) MXPA02009091A (ru)
NO (1) NO330904B1 (ru)
NZ (1) NZ520944A (ru)
PL (1) PL206041B1 (ru)
PT (1) PT1263790E (ru)
RS (1) RS51406B (ru)
SI (1) SI1263790T1 (ru)
SK (1) SK287348B6 (ru)
UA (1) UA78489C2 (ru)
WO (1) WO2001068710A1 (ru)
ZA (1) ZA200206654B (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0114629D0 (en) * 2001-06-15 2001-08-08 Pfizer Ltd Method
ES2401645T3 (es) 2003-06-19 2013-04-23 Merck Serono Sa Uso de agentes moduladores de la conversión de priones
FR2889533B1 (fr) * 2005-08-03 2007-10-12 Lab Francais Du Fractionnement Anticorps diriges contre le recepteur du ldl
FR2889532B1 (fr) * 2005-08-03 2007-10-12 Lab Francais Du Fractionnement Anticorps diriges contre le recepteur du ldl
US20090305258A1 (en) * 2006-02-17 2009-12-10 Paolo La Colla Methods for the diagnosis of proliferative and/or conformational diseases
FR2910896B1 (fr) * 2006-12-29 2012-11-16 Lab Francais Du Fractionnement Anticorps monoclonal dirige contre le recepteur humain des ldl
IL182956A0 (en) 2007-05-03 2008-01-20 Yeda Res & Dev Glycan modified soluble receptors and binding proteins and their use
IL188628A0 (en) * 2008-01-07 2008-12-29 Yeda Res & Dev Use of soluble ldl-r for viral hepatitis
GB0922377D0 (en) * 2009-12-22 2010-02-03 Arab Gulf University The Mutant LDL receptor
CA2800734A1 (en) 2010-05-25 2011-12-01 Universite De Strasbourg Combination of anti-envelope antibodies and anti-receptor antibodies for the treatment and prevention of hcv infection
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2013024155A1 (en) 2011-08-17 2013-02-21 Inserm (Institut National De La Sante Et De La Recherche Medicale) Combinations of anti-hcv-entry factor antibodies and direct acting antivirals for the treatment and the prevention of hcv infection
WO2013024157A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of host targeting agents for the treatment and the prevention of hcv infection
CN103111270B (zh) * 2013-02-26 2015-06-10 王业富 一种乙型肝炎抗原蛋白的吸附材料及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182364A (en) * 1990-02-26 1993-01-26 The Scripps Research Institute Polypeptide analogs of apolipoprotein E
US5496926A (en) * 1992-01-19 1996-03-05 Yeda Research And Development Co. Ltd. Process of preparing a soluble LDL receptor
US5945308A (en) * 1998-04-03 1999-08-31 Incyte Pharmaceuticals, Inc. Human oxidized LDL receptor
JP2000279174A (ja) * 1999-03-30 2000-10-10 Bml Inc ヒトｌｄｌレセプターに対するモノクローナル抗体及びこれを用いる家族性高脂血症の判定方法

Also Published As

Publication number Publication date
MXPA02009091A (es) 2005-06-20
ZA200206654B (en) 2003-10-20
HK1055750A1 (en) 2004-01-21
AU4100201A (en) 2001-09-24
NO330904B1 (no) 2011-08-15
BG65762B1 (bg) 2009-10-30
NO20024223D0 (no) 2002-09-04
SK13122002A3 (sk) 2003-04-01
US6849720B2 (en) 2005-02-01
AU2001241002B2 (en) 2006-04-06
DE60128452D1 (de) 2007-06-28
NO20024223L (no) 2002-10-24
AR028518A1 (es) 2003-05-14
DK1263790T3 (da) 2007-07-02
PL206041B1 (pl) 2010-06-30
US20030186343A1 (en) 2003-10-02
CA2402593A1 (en) 2001-09-20
PT1263790E (pt) 2007-06-01
JP4768193B2 (ja) 2011-09-07
BR0109164A (pt) 2002-11-26
UA78489C2 (en) 2007-04-10
IL151713A0 (en) 2003-04-10
ES2282238T3 (es) 2007-10-16
SK287348B6 (sk) 2010-08-09
CA2402593C (en) 2012-07-03
YU68602A (sh) 2006-03-03
HRP20020704A2 (en) 2004-12-31
CY1108020T1 (el) 2013-09-04
HRP20020704B1 (en) 2011-01-31
RS51406B (sr) 2011-02-28
HUP0300142A2 (hu) 2003-06-28
EE200200517A (et) 2004-02-16
KR100882081B1 (ko) 2009-02-10
WO2001068710A1 (en) 2001-09-20
PL358381A1 (en) 2004-08-09
HUP0300142A3 (en) 2005-07-28
JP2004506603A (ja) 2004-03-04
EA007494B1 (ru) 2006-10-27
CN1418225B (zh) 2012-04-18
IL139217A0 (en) 2001-11-25
KR20020089384A (ko) 2002-11-29
SI1263790T1 (sl) 2007-10-31
DE60128452T2 (de) 2007-09-13
CZ20023098A3 (cs) 2003-02-12
BG107063A (bg) 2003-05-30
CN1418225A (zh) 2003-05-14
HU226194B1 (hu) 2008-06-30
EP1263790B1 (en) 2007-05-16
EP1263790A1 (en) 2002-12-11
AU2001241002B8 (en) 2006-05-04
NZ520944A (en) 2004-04-30
ATE362490T1 (de) 2007-06-15

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU