HRP20231575T1 - Automatski sistem za ubrizgavanje - Google Patents

Automatski sistem za ubrizgavanje Download PDF

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Publication number
HRP20231575T1
HRP20231575T1 HRP20231575TT HRP20231575T HRP20231575T1 HR P20231575 T1 HRP20231575 T1 HR P20231575T1 HR P20231575T T HRP20231575T T HR P20231575TT HR P20231575 T HRP20231575 T HR P20231575T HR P20231575 T1 HRP20231575 T1 HR P20231575T1
Authority
HR
Croatia
Prior art keywords
injection device
automatic injection
flange
syringe
extension
Prior art date
Application number
HRP20231575TT
Other languages
English (en)
Inventor
William Godwin Atterbury
Joseph Daniel Dennis Jr.
Brian Charles Kelley
Mark LAFEVER
Steven Michael Madland
Andrew Thomas SNOW
Jessica Diane Young
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of HRP20231575T1 publication Critical patent/HRP20231575T1/hr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/283—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by telescoping of ampoules or carpules with the syringe body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3148—Means for causing or aiding aspiration or plunger retraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513—Piston constructions to improve sealing or sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/31581—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by rotationally moving or pivoting actuator operated by user, e.g. an injection lever or handle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2086—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically having piston damping means, e.g. axially or rotationally acting retarders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2418—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for damping shocks on ampoule

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Fluid-Driven Valves (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Catching Or Destruction (AREA)
  • Control Of Non-Electrical Variables (AREA)

Claims (18)

1. Automatski uređaj za ubrizgavanje, koji obuhvaća: kućište (22) koje obuhvaća proksimalni kraj (27) i distalni kraj; i špricu (130) koja uključuje iglu (134), tijelo šprice i klip (136), pri čemu se šprica može pomicati unutar kućišta (22) od prvog položaja do drugog položaja koji je distalni u odnosu na prvi položaj kako bi se igla pomaknula prema distalnom kraju kućišta, i pri čemu se klip može pomicati u odnosu na tijelo šprice kako bi se lijek iz tijela šprice ubrizgao kroz iglu; naznačen time da automatski uređaj za ubrizgavanje dalje obuhvaća: „shuttle“ (204) koji ima distalnu površinu (211) koja obuhvaća ispupčenje (213) i krivolinijsku površinu, pri čemu se krivolinijska površina pruža od ispupčenja tako da definira područje (215) podreza, pri čemu je barem odsiječak distalne površine napravljen od materijala s dodatim lubrikantom; i nastavak (250) koji ima tijelo (251) nastavka i zapor (332), pri čemu se zapor može pomicati u odnosu na tijeltijelo nosača i u odnosu na ispupčenje (213) shuttlea (204); pri čemu: nastavak (250) ima spojenu konfiguraciju u kojoj se zapor (332) nategnuto spaja preko ispupčenja (213), i nastavak (250) ima razdvojenu konfiguraciju u kojoj je zapor (332) sklonjen s ispupčenja (213) i u kliznom je zahvatanju sa krivolinijskom površinom, nastavak je rotabilan u odnosu na shuttle (204), i shuttle se može pomicati prema proksimalnom kraju (27) kućišta (22) kako bi se uvukla šprica (130).
2. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 1, pri čemu zapor (332) obuhvaća konzolni krak (330) s jednim krajem koji ima ispupčenje.
3. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 2, pri čemu ispupčenje (332) zapora ima ravnu prednju površinu (333) i zakrivljenu zadnju površinu (335), pri čemu je ravna prednja površina u kontaktu sa ispupčenjem (213) shuttlea (204) kada je nastavak (250) u spojenoj konfiguraciji, i zakrivljena zadnja površina je u kontaktu sa krivolinijskom površinom kada je nastavak u razdvojenoj konfiguraciji.
4. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 1, pri čemu materijal s dodanim lubrikantom obuhvaća silikon.
5. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 1, pri čemu se cijeli shuttle (204) pravi od materijala sa dodanim lubrikantom.
6. Automatski uređaj za ubrizgavanje prema patentnom Zahtjevu 1, koji dalje obuhvaća oprugu (275) koja se tlači između shuttlea (204) i nastavka (250) kada je nastavak u spojenoj konfiguraciji.
7. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 6, pri čemu je opruga (275) torzijski predopterećena kada je nastavak (250) u spojenoj konfiguraciji.
8. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 1, pri čemu se shuttle (204) može pomicati prema proksimalnom kraju kućišta (22) nakon što je nastavak (250) rotiran kroz prethodno određen ugao rotacije.
9. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 1, koji dalje obuhvaća nosač (185) šprica koji uključuje prvi dio (156) i drugi dio (157) koji su međusobno identični, zasebni jedan u odnosu na drugi, i međusobno se zaključavaju, pri čemu svaki od prvog i drugog dijela obuhvaća: proksimalnu površinu (402) prirubnice; distalnu površinu (404) prirubnice; obodni kružni zid (410) između proksimalne površine (402) prirubnice i distalne površine (404) prirubnice; i zazor (460) koji se nalazi između proksimalne površine (402) prirubnice, distalne površine (404) prirubnice i obodnog kružnog zida (410), pri čemu odsječak (133) tijela šprica ulazi u zazor.
10. Automatski uređaj za ubrizgavanje prema patentnom Zahtjevu 9, pri čemu svaki od prvog i drugog dijela (156, 157) nosača (185) šprica uključuje istureni zubac (420) koji se međusobno zaključava sa drugim od prvog i drugog dijela.
11. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 9, pri čemu nosač (185) šprica uključuje jastuk (187), pri čemu proksimalna površina (402) prirubnice i distalna površina (404) prirubnice imaju veću tvrdoću materijala nego jastuk.
12. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 11, pri čemu tijelo šprice uključuje prirubnicu (133) tijela šprice, i jastuče (187) je u kontaktu sa prirubnicom tijela šprice.
13. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 11, pri čemu jastuk (187) uključuje barem jedno radijalno ispupčenje (188) koje se pruža od unutrašnje radijalne površine (189) jastuka.
14. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 9, pri čemu tijelo šprice uključuje prirubnicu (133) tijela šprice, pri čemu obodni kružni zid (410) nosača (185) šprice djelomično okružuje vanjski obujam prirubnice šprice i navedena proksimalna površina (402) prirubnice svakog od dijelova (156, 157) zajedno potpuno preklapa proksimalnu površinu (133A) prirubnice tijela šprice.
15. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 9, pri čemu tijelo šprice uključuje prirubnicu (133) tijela šprice i pri čemu navedena proksimalna površina (402) prirubnice svakog od dijelova (156, 157) zajedno potpuno preklapa proksimalnu površinu (133A) prirubnice tijela šprice.
16. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 9, pri čemu nosač (185) šprice potpuno okružuje vanjski obujam tijela šprice.
17. Automatski uređaj za ubrizgavanje prema patentnom zahtjevu 9, pri čemu svaki od prvog i drugog dijela (156,157) nosača (185) šprice uključuje prvi lateralni kraj (411) zida i drugi lateralni kraj (412) zida, pri čemu se obodni kružni zid (410) pruža od prvog lateralnog kraja zida do drugog lateralnog kraja zida, pri čemu prvi lateralni kraj zida ima zubac (420), i drugi lateralni kraj zida ima ispupčenje (430) zapora, pri čemu se zubac prvog dijela (156) nosača šprice međusobno zaključava sa ispupčenjem zapora drugog dijela (157) nosača šprice.
18. Automatski uređaj za ubrizgavanje prema bilo kom od prethodnih patentnih zahtjeva, pri čemu tijelo šprice sadrži lijek.
HRP20231575TT 2019-03-15 2020-03-06 Automatski sistem za ubrizgavanje HRP20231575T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962818889P 2019-03-15 2019-03-15
EP20716631.5A EP3938013B1 (en) 2019-03-15 2020-03-06 Automatic injection system
PCT/US2020/021321 WO2020190529A1 (en) 2019-03-15 2020-03-06 Automatic injection system

Publications (1)

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HRP20231575T1 true HRP20231575T1 (hr) 2024-03-15

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Application Number Title Priority Date Filing Date
HRP20231575TT HRP20231575T1 (hr) 2019-03-15 2020-03-06 Automatski sistem za ubrizgavanje

Country Status (17)

Country Link
US (2) US11298462B2 (hr)
EP (3) EP4360673A2 (hr)
JP (2) JP6997882B2 (hr)
CN (2) CN116850381A (hr)
AU (2) AU2020241335B2 (hr)
CA (2) CA3196030A1 (hr)
DK (1) DK3938013T3 (hr)
ES (1) ES2960970T3 (hr)
FI (1) FI3938013T3 (hr)
HR (1) HRP20231575T1 (hr)
HU (1) HUE064243T2 (hr)
LT (1) LT3938013T (hr)
PL (1) PL3938013T3 (hr)
PT (1) PT3938013T (hr)
RS (1) RS64885B1 (hr)
SI (1) SI3938013T1 (hr)
WO (1) WO2020190529A1 (hr)

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