HRP20020471B1 - Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates - Google Patents

Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates

Info

Publication number: HRP20020471B1
Authority: HR; Croatia
Prior art keywords: methyl; phenyl; dimethyl; imidazo; acetamide
Prior art date: 1999-11-22

Application number

HR20020471A

Other languages

English (en)

Croatian (hr)

Inventor

Pong� L�szl�

Reiter J�zsef

Simig Gyula

T�mpe P�ter

Hoffmann� Fekete Val�ria

R�v� Endre

Koncz L�szl�

Vereczkeyn� Don�th Gy�rgyi

Nagy K�lm�n

Original Assignee

Egis Gy�gyszergy�r RT

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-22

Filing date

2002-05-28

Publication date

2007-12-31

1999-11-22 Priority claimed from HU9904379A external-priority patent/HU227358B1/hu

1999-11-22 Priority claimed from HU9904377A external-priority patent/HUP9904377A2/hu

2002-05-28 Application filed by Egis Gy�gyszergy�r RT filed Critical Egis Gy�gyszergy�r RT

2005-10-31 Publication of HRP20020471A2 publication Critical patent/HRP20020471A2/hr

2007-12-31 Publication of HRP20020471B1 publication Critical patent/HRP20020471B1/xx

Links

239000000543 intermediate Substances 0.000 title 1
ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
125000000590 4-methylphenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)C([H])([H])[H] 0.000 abstract 1
FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 abstract 1
239000000010 aprotic solvent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

HR20020471A 1999-11-22 2002-05-28 Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates HRP20020471B1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
HU9904379A HU227358B1 (en)	1999-11-22	1999-11-22	Novel process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidyne-3-(n,n-dimethyl-acetamide)
HU9904377A HUP9904377A2 (en)	1999-11-22	1999-11-22	6-methyl-2-(4-methyl-phenyl)-imidazole-[1,2-a]pyrimidine-3-acetic acid-esters and process for their preparation
PCT/HU2000/000120 WO2001038327A2 (en)	1999-11-22	2000-11-22	Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates

Publications (2)

Publication Number	Publication Date
HRP20020471A2 HRP20020471A2 (en)	2005-10-31
HRP20020471B1 true HRP20020471B1 (en)	2007-12-31

Family

ID=90000034

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20020471A HRP20020471B1 (en)	1999-11-22	2002-05-28	Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates

Country Status (15)

Country	Link
EP (1)	EP1259509B1 (ru)
JP (1)	JP2003518016A (ru)
KR (1)	KR100656636B1 (ru)
CN (1)	CN1227252C (ru)
AT (1)	ATE304540T1 (ru)
AU (1)	AU1873901A (ru)
CZ (1)	CZ300711B6 (ru)
DE (1)	DE60022684T2 (ru)
DK (1)	DK1259509T3 (ru)
ES (1)	ES2248154T3 (ru)
HR (1)	HRP20020471B1 (ru)
PL (1)	PL354366A1 (ru)
RU (1)	RU2254334C2 (ru)
SK (1)	SK7122002A3 (ru)
WO (1)	WO2001038327A2 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA05006438A (es)	2002-12-18	2005-09-08	Mallinckrodt Inc	Derivados de acetamidas de heteroarilo.
WO2004087703A1 (en) *	2003-03-12	2004-10-14	Sun Pharmaceutical Industries Limited	Process for the preparation of n,n,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide
DK2446996T3 (en)	2005-05-26	2017-07-24	Alfa Laval Corp Ab	STAINLESS STEEL HEAT EXCHANGE OF STAINLESS STEEL WITH STAINLESS STEEL HEADWARE MATERIAL
JP2009510163A (ja) *	2005-10-03	2009-03-12	マリンクロッド・インコーポレイテッド	ヘミ酒石酸および酒石酸ゾルピデム多形の製造方法
KR101008674B1 (ko) *	2008-01-25	2011-01-18	주식회사 이화창	컨테이너 및 그 컨테이너를 구비한 두피 마사지기
CN103360387B (zh) *	2012-03-28	2016-12-14	江苏豪森药业集团有限公司	一种制备化合物唑吡坦的方法
CN114105974A (zh) *	2020-08-27	2022-03-01	鲁南制药集团股份有限公司	一种唑吡坦的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2151834B1 (es) *	1998-08-06	2001-08-16	Sint Quimica Sa	Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
ES2240074T3 (es) *	1999-03-25	2005-10-16	Synthon B.V.	Sales de zolpidem.

2000
- 2000-11-22 CN CNB008173044A patent/CN1227252C/zh not_active Expired - Fee Related
- 2000-11-22 SK SK712-2002A patent/SK7122002A3/sk unknown
- 2000-11-22 RU RU2002116672/04A patent/RU2254334C2/ru not_active IP Right Cessation
- 2000-11-22 KR KR1020027006461A patent/KR100656636B1/ko not_active IP Right Cessation
- 2000-11-22 WO PCT/HU2000/000120 patent/WO2001038327A2/en active IP Right Grant
- 2000-11-22 ES ES00981505T patent/ES2248154T3/es not_active Expired - Lifetime
- 2000-11-22 CZ CZ20021713A patent/CZ300711B6/cs not_active IP Right Cessation
- 2000-11-22 DE DE60022684T patent/DE60022684T2/de not_active Expired - Fee Related
- 2000-11-22 DK DK00981505T patent/DK1259509T3/da active
- 2000-11-22 EP EP00981505A patent/EP1259509B1/en not_active Expired - Lifetime
- 2000-11-22 AT AT00981505T patent/ATE304540T1/de not_active IP Right Cessation
- 2000-11-22 AU AU18739/01A patent/AU1873901A/en not_active Abandoned
- 2000-11-22 JP JP2001540090A patent/JP2003518016A/ja active Pending
- 2000-11-22 PL PL00354366A patent/PL354366A1/xx not_active IP Right Cessation
2002
- 2002-05-28 HR HR20020471A patent/HRP20020471B1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
RU2254334C2 (ru)	2005-06-20
WO2001038327A3 (en)	2002-09-12
CZ300711B6 (cs)	2009-07-22
DE60022684D1 (de)	2005-10-20
AU1873901A (en)	2001-06-04
ES2248154T3 (es)	2006-03-16
CZ20021713A3 (cs)	2002-08-14
SK7122002A3 (en)	2002-10-08
HRP20020471A2 (en)	2005-10-31
EP1259509A1 (en)	2002-11-27
KR100656636B1 (ko)	2006-12-11
CN1413212A (zh)	2003-04-23
CN1227252C (zh)	2005-11-16
WO2001038327A2 (en)	2001-05-31
PL354366A1 (en)	2004-01-12
DK1259509T3 (da)	2006-01-16
DE60022684T2 (de)	2006-06-29
JP2003518016A (ja)	2003-06-03
ATE304540T1 (de)	2005-09-15
EP1259509B1 (en)	2005-09-14
KR20020052213A (ko)	2002-07-02

Similar Documents

Publication	Publication Date	Title
ES8204739A1 (es)	1982-05-01	Un procedimiento para preparar compuestos de cefem
CA2209487A1 (en)	1996-07-18	Imidazo[4,5-c]quinoline amines
EP0747383A3 (en)	1996-12-18	Polyamine salts of clavulanic acid
ATE399753T1 (de)	2008-07-15	Amide als pyruvatdehydrogenaseinhibitoren
KR880012526A (ko)	1988-11-28	l-페닐-3-나프탈레닐옥시프로판아민
EP1038875A3 (en)	2001-09-12	Imidazopyridine derivatives and process for making them
HRP20020471B1 (en)	2007-12-31	Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates
MX9705559A (es)	1998-05-31	Derivados de acido neuraminico, su preparacion y su uso en medicina.
WO2003010142A3 (en)	2003-08-28	A process for the preparation of perindopril, its analgous compounds and salts thereof using 2,5 -dioxo-oxazolidine intermediate compounds
WO1999020639A3 (en)	1999-07-08	NOVEL 3,6-HEMIKETALS FROM THE CLASS OF 9a-AZALIDES
AU3759101A (en)	2001-09-17	Process for the preparation of citalopram
IE863374L (en)	1987-06-23	Indoles.
BRPI0013750B8 (pt)	2021-05-25	intermediários para a produção de derivados de ácido naftiridina-3-carboxílico
IE882938L (en)	1989-03-30	Phosphinic acid derivatives
CA2273894A1 (en)	1998-06-11	Novel n-benzenesulphonyl-l-proline derivatives, method for preparing and therapeutic use
WO1993015061A3 (de)	1993-10-14	Verfahren zur herstellung von 2-arylbenzimidazol-5-sulfonsäuren
ES2167869T3 (es)	2002-05-16	Procedimiento para preparar acidos nicotinicos.
CA2383829A1 (en)	2001-03-29	Process for preparing methylene bisphosphonic and salts
GB1418784A (en)	1975-12-24	Phosphorus containing pyrimidine compounds and pesticidal compositions comprising them
CA2277151A1 (en)	1998-08-13	Synthesis of acyclic nucleoside derivatives
NZ333769A (en)	2000-03-27	A process for preparing naphthyridones and azabicyclo(3.1.0)hexane intermediates for the compound trovafloxacin and derivatives thereof
JPS5772981A (en)	1982-05-07	1,8-naphthyridine derivative and its salt
JPS56139461A (en)	1981-10-30	Preparation of alpha-aryl-alpha-alkylpyridineacetic acid amides
CA2151817A1 (en)	1994-07-07	Process for the preparation of hydroxylamine ethers and their salts and intermediates for this purpose
DE69026638D1 (de)	1996-05-30	Verfahren zur Herstellung von Pyrido[1,2-a]pyrimidinderivaten

Legal Events

Date	Code	Title	Description
2005-10-31	A1OB	Publication of a patent application
2006-02-10	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
2007-12-31	B1PR	Patent granted
2008-10-17	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20081017 Year of fee payment: 9
2010-05-23	PBON	Lapse due to non-payment of renewal fee	Effective date: 20091123