HK54780A - Novel b-lactam antibiotic from streptomyces clavuligerus - Google Patents

Novel b-lactam antibiotic from streptomyces clavuligerus

Info

Publication number
HK54780A
HK54780A HK547/80A HK54780A HK54780A HK 54780 A HK54780 A HK 54780A HK 547/80 A HK547/80 A HK 547/80A HK 54780 A HK54780 A HK 54780A HK 54780 A HK54780 A HK 54780A
Authority
HK
Hong Kong
Prior art keywords
novel
lactam antibiotic
streptomyces clavuligerus
clavuligerus
streptomyces
Prior art date
Application number
HK547/80A
Other languages
English (en)
Inventor
T Howarth
M Cole
C Reading
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27448389&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK54780(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB17410/74A external-priority patent/GB1508977A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of HK54780A publication Critical patent/HK54780A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK547/80A 1974-04-20 1980-09-25 Novel b-lactam antibiotic from streptomyces clavuligerus HK54780A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB17410/74A GB1508977A (en) 1974-04-20 1974-04-20 Beta-lactam antibiotic from streptomyces clavuligerus
GB2771574 1974-06-21
GB4365174 1974-10-09
GB5352574 1974-12-11

Publications (1)

Publication Number Publication Date
HK54780A true HK54780A (en) 1980-10-03

Family

ID=27448389

Family Applications (1)

Application Number Title Priority Date Filing Date
HK547/80A HK54780A (en) 1974-04-20 1980-09-25 Novel b-lactam antibiotic from streptomyces clavuligerus

Country Status (26)

Country Link
US (5) US4427690A (nl)
JP (7) JPS5246957B2 (nl)
AR (3) AR206627A1 (nl)
CA (1) CA1059050A (nl)
CH (2) CH629252A5 (nl)
CY (1) CY1078A (nl)
DD (2) DD121799A5 (nl)
DE (4) DE2559410A1 (nl)
DK (1) DK141254B (nl)
FI (1) FI54144C (nl)
FR (1) FR2267778B1 (nl)
HK (1) HK54780A (nl)
IE (1) IE41109B1 (nl)
IL (1) IL47087A (nl)
IN (1) IN140042B (nl)
KE (1) KE3076A (nl)
LU (1) LU72322A1 (nl)
MY (1) MY8100195A (nl)
NL (1) NL163824C (nl)
NO (3) NO145247C (nl)
NZ (1) NZ177159A (nl)
OA (1) OA05203A (nl)
PH (1) PH16474A (nl)
RO (2) RO69984A (nl)
SE (8) SE422063B (nl)
YU (3) YU39941B (nl)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
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CH624956A5 (de) * 1975-02-07 1981-08-31 Glaxo Operations Ltd Verfahren zur entfernung von verunreinigungen aus clavulansaeure.
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US6218380B1 (en) * 1975-04-17 2001-04-17 Smithkline Beecham P.L.C. Pharmaceutical compositions
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IT1078465B (it) * 1976-06-08 1985-05-08 Glaxo Lab Ltd Composti fungicidi per agricoltura composizioni che li contengono e procedimento per produrli
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GB1594001A (en) * 1977-03-16 1981-07-30 Beecham Group Ltd Pellets suitable for use in the testing of microorganisms
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DE2912511C2 (de) * 1977-06-07 1982-06-24 Pfizer Inc., 10017 New York, N.Y. Pharmazeutische Zusammensetzung, enthaltend Penicillansäure
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NZ177159A (en) 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions
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CH624956A5 (de) * 1975-02-07 1981-08-31 Glaxo Operations Ltd Verfahren zur entfernung von verunreinigungen aus clavulansaeure.
US4144242A (en) * 1975-02-07 1979-03-13 Glaxo Laboratories Limited Process for the purification of clavulanic acid
JO984B1 (en) * 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration

Also Published As

Publication number Publication date
US4427690A (en) 1984-01-24
SE8605405D0 (sv) 1986-12-16
JPS5549831B2 (nl) 1980-12-15
US4525352A (en) 1985-06-25
JPS5246957B2 (nl) 1977-11-29
SE7811203L (sv) 1978-10-27
YU39941B (en) 1985-06-30
SE8306328D0 (sv) 1983-11-16
JPS532495A (en) 1978-01-11
US4526783A (en) 1985-07-02
DE2517316C2 (de) 1985-03-07
JPS533589A (en) 1978-01-13
YU42744B (en) 1988-12-31
DE2560074C2 (de) 1985-03-28
AR206627A1 (es) 1976-08-06
DK141254B (da) 1980-02-11
YU274481A (en) 1983-06-30
NO145247C (no) 1982-02-10
SE8306328L (sv) 1983-11-16
IE41109B1 (en) 1979-10-24
NL163824B (nl) 1980-05-16
JPS533588A (en) 1978-01-13
NO801852L (no) 1975-10-21
JPS533590A (en) 1978-01-13
SE7811201L (sv) 1978-10-27
CY1078A (en) 1980-12-27
AR219050A1 (es) 1980-07-31
JPS50142789A (nl) 1975-11-17
DD132297A5 (de) 1978-09-20
SE446687B (sv) 1986-10-06
JPS532494A (en) 1978-01-11
JPS5549832B2 (nl) 1980-12-15
DK167275A (nl) 1975-10-21
MY8100195A (en) 1981-12-31
NZ177159A (en) 1978-03-06
NL7504621A (nl) 1975-10-22
FI751133A (nl) 1975-10-21
DE2559411A1 (de) 1976-10-21
PH16474A (en) 1983-10-25
CH629252A5 (de) 1982-04-15
JPS5549830B2 (nl) 1980-12-15
YU274381A (en) 1983-06-30
SE453600B (sv) 1988-02-15
RO77320A (ro) 1981-08-17
IN140042B (nl) 1976-09-04
SE8105829L (sv) 1981-10-02
DD121799A5 (nl) 1976-08-20
NL163824C (nl) 1980-10-15
KE3076A (en) 1980-10-03
YU42745B (en) 1988-12-31
IL47087A0 (en) 1975-06-25
FI54144C (fi) 1978-10-10
US4560552C1 (en) 2001-10-16
OA05203A (fr) 1981-02-28
NO150838C (no) 1985-01-09
RO69984A (ro) 1980-12-30
FR2267778B1 (nl) 1978-11-17
SE8605405L (sv) 1986-12-16
NO145247B (no) 1981-11-02
JPS521996B2 (nl) 1977-01-19
NO150838B (no) 1984-09-17
SE435286B (sv) 1984-09-17
IL47087A (en) 1979-07-25
JPS50142591A (nl) 1975-11-17
DE2559410A1 (de) 1976-09-23
CA1059050A (en) 1979-07-24
CH630631A5 (de) 1982-06-30
YU90875A (en) 1982-05-31
US4560552A (en) 1985-12-24
LU72322A1 (nl) 1975-08-20
SE7811200L (sv) 1978-10-27
DE2517316A1 (de) 1975-10-23
DK141254C (nl) 1980-08-11
SE7504541L (nl) 1975-12-19
AR216430A1 (es) 1979-12-28
SE443562B (sv) 1986-03-03
SE435287B (sv) 1984-09-17
FR2267778A1 (nl) 1975-11-14
IE41109L (en) 1975-10-20
NO751407L (nl) 1975-10-21
NO791956L (no) 1975-10-21
FI54144B (fi) 1978-06-30
SE7811202L (sv) 1978-10-27
US4556559A (en) 1985-12-03
DE2559411C2 (de) 1982-07-01
SE422063B (sv) 1982-02-15
JPS5549833B2 (nl) 1980-12-15

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