HK1219050A1 - 免疫保護性原代間充質幹細胞和方法 - Google Patents

免疫保護性原代間充質幹細胞和方法

Info

Publication number
HK1219050A1
HK1219050A1 HK16107097.9A HK16107097A HK1219050A1 HK 1219050 A1 HK1219050 A1 HK 1219050A1 HK 16107097 A HK16107097 A HK 16107097A HK 1219050 A1 HK1219050 A1 HK 1219050A1
Authority
HK
Hong Kong
Prior art keywords
methods
stem cells
mesenchymal stem
primary mesenchymal
immunoprotective primary
Prior art date
Application number
HK16107097.9A
Other languages
English (en)
Inventor
Robert F Garry
Luis M Branco
Bruce A Bunnell
Russell B Wilson
Samuel E Hopkins
Original Assignee
The Administrators Of The Tulane Educational Fund
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Administrators Of The Tulane Educational Fund filed Critical The Administrators Of The Tulane Educational Fund
Publication of HK1219050A1 publication Critical patent/HK1219050A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
HK16107097.9A 2013-03-14 2016-06-21 免疫保護性原代間充質幹細胞和方法 HK1219050A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/826,285 US9101597B2 (en) 2013-03-14 2013-03-14 Immunoprotective primary mesenchymal stem cells and methods
PCT/US2014/025941 WO2014160157A1 (en) 2013-03-14 2014-03-13 Immunoprotective primary mesenchymal stem cells and methods

Publications (1)

Publication Number Publication Date
HK1219050A1 true HK1219050A1 (zh) 2017-03-24

Family

ID=51527936

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16107097.9A HK1219050A1 (zh) 2013-03-14 2016-06-21 免疫保護性原代間充質幹細胞和方法

Country Status (13)

Country Link
US (4) US9101597B2 (zh)
EP (1) EP2968611B1 (zh)
JP (1) JP6566932B2 (zh)
CN (1) CN105188768B (zh)
AR (1) AR095368A1 (zh)
AU (1) AU2014244057B2 (zh)
CA (1) CA2906592C (zh)
EA (1) EA201591673A1 (zh)
ES (1) ES2881383T3 (zh)
HK (1) HK1219050A1 (zh)
MX (3) MX366419B (zh)
TW (2) TWI650420B (zh)
WO (1) WO2014160157A1 (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9101597B2 (en) * 2013-03-14 2015-08-11 The Administration Of The Tulane Educational Fund Immunoprotective primary mesenchymal stem cells and methods
US11357866B2 (en) * 2013-04-03 2022-06-14 The Administrators Of The Tulane Educational Fund Expression of HIV inhibitors by mesenchymal stem cells
CN106659742B (zh) 2014-08-18 2021-09-03 埃普塞斯有限责任两合公司 表达免疫应答刺激细胞因子以吸引和/或激活免疫细胞的基因修饰间充质干细胞
WO2016196740A1 (en) * 2015-06-02 2016-12-08 The Rockefeller University Tri-specific antibodies for hiv therapy
EP3411050B1 (en) 2016-02-04 2023-09-27 Longeveron Inc. Mesenchymal stem cells as vaccine adjuvants and methods for using the same
CN109561691A (zh) * 2016-06-07 2019-04-02 太平洋心肺血研究所 用于治疗癌症的组合物和方法
WO2018106712A1 (en) * 2016-12-05 2018-06-14 The Administrators Of The Tulane Educational Fund Arenavirus monoclonal antibodies and uses
CN114375300A (zh) * 2019-09-05 2022-04-19 克里斯珀医疗股份公司 通用供体细胞
CN111363045B (zh) * 2020-02-18 2021-12-17 厦门大学 一种流感、hiv嵌合蛋白及嵌合病毒疫苗的制备方法
US20230105667A1 (en) * 2020-03-12 2023-04-06 Exostem Biotec Ltd. Mesenchymal stromal cells and extracellular vesicles for treating viral infections, inflammation, and tissue fibrosis
EP3881853A1 (en) * 2020-03-20 2021-09-22 Promethera Therapeutics Sa Human allogeneic liver-derived progenitor cells for use in the treatment of inflammatory and infectious lung diseases and systemic inflammation
US20210299246A1 (en) * 2020-03-27 2021-09-30 R. Brannon Claytor Methods and compositions for therapeutic treatment of viral or virally-induced infections and conditions, and anti-viral compositions and their production
US11578309B2 (en) 2020-12-31 2023-02-14 Crispr Therapeutics Ag Universal donor cells

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US20040039186A1 (en) * 1997-02-28 2004-02-26 Boehringer Ingelheim Pharmaceuticals, Inc. Self-regulated apoptosis of inflammatory cells by gene therapy
US6149906A (en) * 1997-09-20 2000-11-21 Osiris Therapeutics, Inc. Antigen presenting cells of the adipocyte lineage
CA2436091A1 (en) 2001-01-26 2002-08-01 Abgenix, Inc. Neutralizing human monoclonal antibodies against hiv-1, their production and uses
US20070196365A1 (en) * 2001-02-20 2007-08-23 Dov Zipori Immunoglobulin heavy chain variants expressed in mesenchymal cells and therapeutic uses thereof
EP1456358A2 (en) * 2001-09-20 2004-09-15 Centre for Translational Research in Cancer Cultured stromal cells and uses thereof
JPWO2005094846A1 (ja) * 2004-03-30 2008-02-14 株式会社レノメディクス研究所 プリオン病治療剤およびその製造方法
CN101166546A (zh) * 2005-01-21 2008-04-23 因特罗根治疗公司 允许靶细胞长期暴露于治疗性和预防性核酸的局部施用
BRPI0609808A2 (pt) 2005-05-18 2011-10-11 Biofactura Inc vetor , célula hospedeira, kit, composição dos suplementos de cultura celular, e, métodos para selecionar células que possam sobreviver em meio sem colesterol, para se obter células que tenham a capacidade de sobreviver em um meio desprovido de colesterol e produzir uma proteìna heteróloga, e para expressar uma proteìna heteróloga
CN1872344A (zh) * 2005-06-01 2006-12-06 上海二医新生基因科技有限公司 人异体间质干细胞（携带治疗基因）的基因治疗方法
CN103435697A (zh) 2006-05-15 2013-12-11 航道生物技术有限责任公司 流感病毒的中和抗体
EP1995309A1 (en) 2007-05-21 2008-11-26 Vivalis Recombinant protein production in avian EBx® cells
CA2721870C (en) * 2008-04-21 2020-12-22 Tissue Regeneration Therapeutics, Inc. Genetically modified human umbilical cord perivascular cells for prophylaxis against or treatment of biological or chemical agents
US10472647B2 (en) * 2012-12-21 2019-11-12 The Administrators Of The Tulane Educational Fund Primary mesenchymal stem cells as a vaccine platform
US9707322B2 (en) * 2012-12-21 2017-07-18 University Of Connecticut Gradient porous scaffolds
US9101597B2 (en) * 2013-03-14 2015-08-11 The Administration Of The Tulane Educational Fund Immunoprotective primary mesenchymal stem cells and methods

Also Published As

Publication number Publication date
US20160129110A1 (en) 2016-05-12
AR095368A1 (es) 2015-10-14
CA2906592C (en) 2022-01-18
AU2014244057B2 (en) 2018-12-06
EA201591673A1 (ru) 2016-01-29
WO2014160157A1 (en) 2014-10-02
TW201514301A (zh) 2015-04-16
EP2968611B1 (en) 2021-05-05
US11123427B2 (en) 2021-09-21
JP2016518819A (ja) 2016-06-30
CN105188768A (zh) 2015-12-23
TWI650420B (zh) 2019-02-11
US20140271580A1 (en) 2014-09-18
US9101597B2 (en) 2015-08-11
US20210401984A1 (en) 2021-12-30
TWI689590B (zh) 2020-04-01
EP2968611A1 (en) 2016-01-20
MX366419B (es) 2019-07-08
AU2014244057A1 (en) 2015-10-29
CA2906592A1 (en) 2014-10-02
ES2881383T3 (es) 2021-11-29
TW201907005A (zh) 2019-02-16
MX2015013387A (es) 2016-08-11
EP2968611A4 (en) 2016-08-17
MX2019000704A (es) 2020-11-12
CN105188768B (zh) 2019-06-28
MX2019008195A (es) 2019-09-11
US20190282694A1 (en) 2019-09-19
JP6566932B2 (ja) 2019-08-28
US10357562B2 (en) 2019-07-23

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