US6143496A
(en)
*
|
1997-04-17 |
2000-11-07 |
Cytonix Corporation |
Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
|
JP2002233382A
(ja)
*
|
2001-02-09 |
2002-08-20 |
Sapporo Breweries Ltd |
ビール酵母の識別方法
|
RU2344821C2
(ru)
*
|
2002-07-30 |
2009-01-27 |
Уайт |
Парентеральные композиции, содержащие гидроксиэфиры рапамицина
|
AU2003902299A0
(en)
*
|
2003-05-13 |
2003-05-29 |
Flinders Medical Centre |
A method of analysing a marker nucleic acid molecule
|
CA2544367A1
(en)
*
|
2003-10-29 |
2005-05-12 |
Ribomed Biotechnologies, Inc. |
Compositions, methods and detection technologies for reiterative oligonucleotide synthesis
|
FR2863274B1
(fr)
*
|
2003-12-05 |
2012-11-16 |
Commissariat Energie Atomique |
Procede d'evaluation quantitative d'un rearrangement ou d'une recombinaison genetique ciblee d'un individu et ses applications.
|
WO2006046860A1
(en)
*
|
2004-10-25 |
2006-05-04 |
Erasmus Universiteit Rotterdam |
Determining the replicative history of lymphocytes
|
DK1871912T3
(da)
*
|
2005-04-15 |
2012-05-14 |
Epigenomics Ag |
Fremgangsmåde til bestemmelse af DNA-methylering i blod- eller urinprøver
|
DK2620510T4
(da)
|
2005-06-15 |
2020-03-30 |
Complete Genomics Inc |
Enkeltmolekyle-arrays til genetisk og kemisk analyse
|
WO2007123392A1
(en)
*
|
2006-04-24 |
2007-11-01 |
Erasmus Universiteit Rotterdam |
Determining the replicative history of lymphocytes
|
US20080050724A1
(en)
*
|
2006-08-24 |
2008-02-28 |
Microfluidic Systems, Inc. |
Method of detecting one or more limited copy targets
|
WO2008026927A2
(en)
*
|
2006-08-30 |
2008-03-06 |
Academisch Medisch Centrum |
Process for displaying t- and b-cell receptor repertoires
|
WO2008046056A1
(en)
*
|
2006-10-13 |
2008-04-17 |
Welldoc Communications, Inc. |
Reduction of nonspecific binding in nucleic acid assays and nucleic acid synthesis reactions
|
JP5730568B2
(ja)
*
|
2007-06-01 |
2015-06-10 |
モノクアント・ピーティーワイ・リミテッド |
Dna切断点の分析のための方法
|
EP2062982A1
(de)
*
|
2007-11-26 |
2009-05-27 |
ImmunID |
Verfahren zur Untersuchung der kombinatorischen Diversität von V(D)J.
|
US20160068905A1
(en)
|
2007-11-26 |
2016-03-10 |
Immunid |
Method for Studying V(D)J Combinatory Diversity
|
US8592150B2
(en)
|
2007-12-05 |
2013-11-26 |
Complete Genomics, Inc. |
Methods and compositions for long fragment read sequencing
|
ES2549184T3
(es)
*
|
2008-04-16 |
2015-10-23 |
Cb Biotechnologies, Inc. |
Método para evaluar y comparar inmunorepertorios
|
EP2806037B1
(de)
*
|
2008-05-13 |
2016-09-21 |
Gen-Probe Incorporated |
Inaktivierbare Target-Capture-Oligomere zur Verwendung bei der selektiven Hybridisierung und beim Fangen von Zielnukleinsäuresequenzen
|
US8691510B2
(en)
|
2008-11-07 |
2014-04-08 |
Sequenta, Inc. |
Sequence analysis of complex amplicons
|
US8748103B2
(en)
|
2008-11-07 |
2014-06-10 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
AU2009311588B2
(en)
|
2008-11-07 |
2016-07-28 |
Adaptive Biotechnologies Corp. |
Methods of monitoring conditions by sequence analysis
|
US9365901B2
(en)
|
2008-11-07 |
2016-06-14 |
Adaptive Biotechnologies Corp. |
Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
|
US9528160B2
(en)
|
2008-11-07 |
2016-12-27 |
Adaptive Biotechnolgies Corp. |
Rare clonotypes and uses thereof
|
US9506119B2
(en)
|
2008-11-07 |
2016-11-29 |
Adaptive Biotechnologies Corp. |
Method of sequence determination using sequence tags
|
US9394567B2
(en)
|
2008-11-07 |
2016-07-19 |
Adaptive Biotechnologies Corporation |
Detection and quantification of sample contamination in immune repertoire analysis
|
US8628927B2
(en)
|
2008-11-07 |
2014-01-14 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
US20100124741A1
(en)
*
|
2008-11-18 |
2010-05-20 |
Quest Disgnostics Investments Incorporated |
METHODS FOR DETECTING IgH/BCL-1 CHROMOSOMAL TRANSLOCATION
|
US8367330B2
(en)
|
2008-12-22 |
2013-02-05 |
Quest Diagnostics Investments Incorporated |
Methods for detecting TCR-gamma gene rearrangement
|
HUE029424T2
(en)
|
2009-01-15 |
2017-02-28 |
Adaptive Biotechnologies Corp |
Adaptive immunity profiling and a method for producing monoclonal antibodies
|
US9524369B2
(en)
|
2009-06-15 |
2016-12-20 |
Complete Genomics, Inc. |
Processing and analysis of complex nucleic acid sequence data
|
KR20120044941A
(ko)
|
2009-06-25 |
2012-05-08 |
프레드 헛친슨 켄서 리서치 센터 |
적응 면역의 측정방법
|
US9043160B1
(en)
|
2009-11-09 |
2015-05-26 |
Sequenta, Inc. |
Method of determining clonotypes and clonotype profiles
|
EE201000013A
(et)
*
|
2010-01-29 |
2011-10-17 |
Selfdiagnostics O� |
Meetod ja kiirtesti seade sihtmrk-molekuli proovimaterjalist detekteerimiseks
|
JP2011223940A
(ja)
*
|
2010-04-21 |
2011-11-10 |
Asahi Breweries Ltd |
偽陰性を排除するpcr検査方法およびそれに使用するプライマー
|
JP6158080B2
(ja)
|
2010-05-06 |
2017-07-05 |
アダプティヴ バイオテクノロジーズ コーポレーション |
クロノタイププロファイルを用いた健康状態および疾患状態のモニタリング
|
EP2612120B1
(de)
*
|
2010-08-31 |
2019-04-10 |
Canon U.S. Life Sciences, Inc. |
Wärmekalibrierung
|
US11022573B2
(en)
*
|
2010-08-31 |
2021-06-01 |
Canon U.S.A., Inc. |
Positive controls
|
CN103797366A
(zh)
|
2011-01-14 |
2014-05-14 |
Cb生物技术公司 |
免疫多样性评估方法及其用途
|
JP2014513557A
(ja)
*
|
2011-05-17 |
2014-06-05 |
ディクステリティー ダイアグノスティクス インコーポレイテッド |
標的核酸を検出する方法及び組成物
|
WO2013010074A1
(en)
|
2011-07-13 |
2013-01-17 |
Primeradx, Inc. |
Multimodal methods for simultaneous detection and quantification of multiple nucleic acids in a sample
|
US10385475B2
(en)
|
2011-09-12 |
2019-08-20 |
Adaptive Biotechnologies Corp. |
Random array sequencing of low-complexity libraries
|
US9279159B2
(en)
|
2011-10-21 |
2016-03-08 |
Adaptive Biotechnologies Corporation |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
EP3848474A1
(de)
|
2011-11-04 |
2021-07-14 |
Gen-Probe Incorporated |
Molekulartestreagenzien und -verfahren
|
ES2683037T3
(es)
|
2011-12-09 |
2018-09-24 |
Adaptive Biotechnologies Corporation |
Diagnóstico de tumores malignos linfoides y detección de enfermedad residual mínima
|
US9499865B2
(en)
|
2011-12-13 |
2016-11-22 |
Adaptive Biotechnologies Corp. |
Detection and measurement of tissue-infiltrating lymphocytes
|
GB201203720D0
(en)
*
|
2012-03-02 |
2012-04-18 |
Babraham Inst |
Method of identifying VDJ recombination products
|
DK2823060T3
(en)
|
2012-03-05 |
2018-05-28 |
Adaptive Biotechnologies Corp |
Determination of associated immune receptor chains from frequency-matched subunits
|
CN102605070A
(zh)
*
|
2012-03-19 |
2012-07-25 |
中国人民解放军第二军医大学 |
淋巴细胞基因重排克隆性检测试剂盒及其检测方法
|
EP2831276B1
(de)
*
|
2012-05-08 |
2016-04-20 |
Adaptive Biotechnologies Corporation |
Zusammensetzungen und verfahren zum vermessen und kalibrieren eines amplifizierungs-bias in multiplexierten pcr-reaktionen
|
WO2014055561A1
(en)
|
2012-10-01 |
2014-04-10 |
Adaptive Biotechnologies Corporation |
Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization
|
EP2959020B1
(de)
|
2013-02-22 |
2019-09-18 |
Adaptive Biotechnologies Corporation |
Verfahren zur auswahl von seltene klonotypen
|
US10119134B2
(en)
|
2013-03-15 |
2018-11-06 |
Abvitro Llc |
Single cell bar-coding for antibody discovery
|
US20160115544A1
(en)
*
|
2013-06-07 |
2016-04-28 |
Athena Diagnostics, Inc. |
Molecular barcoding for multiplex sequencing
|
US9708657B2
(en)
|
2013-07-01 |
2017-07-18 |
Adaptive Biotechnologies Corp. |
Method for generating clonotype profiles using sequence tags
|
WO2015063121A1
(en)
*
|
2013-10-29 |
2015-05-07 |
Region Syddanmark |
Method for analyzing body fluid samples
|
US20160326571A1
(en)
*
|
2013-10-31 |
2016-11-10 |
Atherotech, Inc. |
Methods for nucleic acid amplification
|
EP3091074B1
(de)
|
2013-11-21 |
2019-08-07 |
Repertoire Genesis Incorporation |
Analysesystem für t-zellrezeptor- und b-zellrezeptorrepertoir und seine verwendung zur behandlung und diagnose
|
US20170292149A1
(en)
|
2014-03-05 |
2017-10-12 |
Adaptive Biotechnologies Corporation |
Methods using randomer-containing synthetic molecules
|
US11390921B2
(en)
|
2014-04-01 |
2022-07-19 |
Adaptive Biotechnologies Corporation |
Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs)
|
US10066265B2
(en)
|
2014-04-01 |
2018-09-04 |
Adaptive Biotechnologies Corp. |
Determining antigen-specific t-cells
|
EP3126524B1
(de)
*
|
2014-04-04 |
2020-07-22 |
Affymetrix, Inc. |
Verbesserte zusammensetzungen und verfahren für molekularinversionsprobenassays
|
ES2777529T3
(es)
|
2014-04-17 |
2020-08-05 |
Adaptive Biotechnologies Corp |
Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células
|
US10202640B2
(en)
|
2014-05-07 |
2019-02-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
Single cell analysis of T cells using high-throughput multiplex amplification and deep sequencing
|
SG11201702060VA
(en)
|
2014-09-15 |
2017-04-27 |
Abvitro Inc |
High-throughput nucleotide library sequencing
|
ES2784343T3
(es)
|
2014-10-29 |
2020-09-24 |
Adaptive Biotechnologies Corp |
Detección simultánea altamente multiplexada de ácidos nucleicos que codifican heterodímeros de receptores inmunes adaptativos emparejados de muchas muestras
|
EP3018214B1
(de)
|
2014-11-05 |
2017-12-13 |
Fundacion de Investigacion Hospital 12 de Octubre |
Verfahren zur Quantifizierung des Niveaus minimaler Resterkrankung bei einer Person
|
US10246701B2
(en)
|
2014-11-14 |
2019-04-02 |
Adaptive Biotechnologies Corp. |
Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
|
AU2015353581A1
(en)
|
2014-11-25 |
2017-06-15 |
Adaptive Biotechnologies Corporation |
Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
|
CA2976580A1
(en)
|
2015-02-24 |
2016-09-01 |
Adaptive Biotechnologies Corp. |
Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing
|
US11041202B2
(en)
|
2015-04-01 |
2021-06-22 |
Adaptive Biotechnologies Corporation |
Method of identifying human compatible T cell receptors specific for an antigenic target
|
US11124823B2
(en)
|
2015-06-01 |
2021-09-21 |
Becton, Dickinson And Company |
Methods for RNA quantification
|
JP6714709B2
(ja)
*
|
2016-01-29 |
2020-06-24 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
核酸配列決定のための新規アダプターおよび使用法
|
US11459619B2
(en)
|
2016-02-08 |
2022-10-04 |
The Johns Hopkins University |
Handheld nucleic acid-based assay for rapid identification
|
US20170226593A1
(en)
*
|
2016-02-08 |
2017-08-10 |
The Johns Hopkins University |
Handheld nucleic acid-based assay for rapid identification
|
US20190017112A1
(en)
*
|
2016-02-11 |
2019-01-17 |
Htg Molecular Diagnostics, Inc. |
Method of direct target sequencing using nuclease protection
|
EP3432796A4
(de)
*
|
2016-03-23 |
2019-09-18 |
The Methodist Hospital System |
Beurteilung der tcr-klonalität vor einer transplantation zur vorhersage des überlebens nach einer lebertransplantation
|
US20170275680A1
(en)
*
|
2016-03-24 |
2017-09-28 |
Paul Chi Hang Li |
Methods and Apparatus for Nanoparticle-assisted Nucleic Acid Amplification, Hybridization and Microarray Analysis
|
WO2017174572A1
(en)
*
|
2016-04-04 |
2017-10-12 |
F. Hoffmann-La Roche Ag |
Nucleic acid sample preparation methods
|
CN106191262A
(zh)
*
|
2016-07-18 |
2016-12-07 |
南开大学 |
一种分析Igκ基因二次重排中间产物的方法及试剂盒
|
US20180037942A1
(en)
*
|
2016-08-03 |
2018-02-08 |
Cellular Research, Inc. |
Enzyme-independent molecular indexing
|
US10428325B1
(en)
|
2016-09-21 |
2019-10-01 |
Adaptive Biotechnologies Corporation |
Identification of antigen-specific B cell receptors
|
CN106701954A
(zh)
*
|
2017-01-09 |
2017-05-24 |
浙江大学 |
一种用于检测肝癌的引物组及检测方法
|
US10822662B2
(en)
|
2017-03-06 |
2020-11-03 |
Karkinos Precision Oncology LLC |
Diagnostic methods for identifying T-cell lymphoma and leukemia by high-throughput TCR-β sequencing
|
CN108823306A
(zh)
*
|
2017-05-03 |
2018-11-16 |
杭州赫玛生物科技有限公司 |
检测白血病细胞的***和方法
|
CN112204155A
(zh)
*
|
2017-10-10 |
2021-01-08 |
纪念斯隆-凯特林癌症中心 |
引物提取和克隆性检测的***和方法
|
US11254980B1
(en)
|
2017-11-29 |
2022-02-22 |
Adaptive Biotechnologies Corporation |
Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
|
CH714402A1
(fr)
*
|
2017-12-04 |
2019-06-14 |
Fond Luc Montagnier |
Procédé de détection de la présence d'un élément biochimique.
|
US11946095B2
(en)
|
2017-12-19 |
2024-04-02 |
Becton, Dickinson And Company |
Particles associated with oligonucleotides
|
JP2021526824A
(ja)
*
|
2018-06-11 |
2021-10-11 |
モノクアント・ピーティーワイ・リミテッド |
増幅方法及びそこで使用されるプライマー
|
CN110656161B
(zh)
*
|
2018-06-28 |
2022-12-13 |
苏州云泰生物医药科技有限公司 |
用于检测人免疫球蛋白基因重排的毛细管电泳试剂盒及其使用方法
|
US20220073983A1
(en)
*
|
2018-07-18 |
2022-03-10 |
Life Technologies Corporation |
Compositions and methods for immune repertoire sequencing
|
EP3908678A1
(de)
|
2019-01-10 |
2021-11-17 |
Iovance Biotherapeutics, Inc. |
System und verfahren zur überwachung der klonalität und persistenz von adoptiven zelltherapien
|
WO2020150356A1
(en)
|
2019-01-16 |
2020-07-23 |
Becton, Dickinson And Company |
Polymerase chain reaction normalization through primer titration
|
WO2023076832A1
(en)
*
|
2021-10-25 |
2023-05-04 |
Singular Genomics Systems, Inc. |
Manipulating and detecting biological samples
|
CN113957128A
(zh)
*
|
2021-12-21 |
2022-01-21 |
迈杰转化医学研究(苏州)有限公司 |
一种核酸完整性评估试剂盒及评估方法
|
CN117363722A
(zh)
*
|
2023-12-07 |
2024-01-09 |
北京旌准医疗科技有限公司 |
一种用于检测igk和igl基因的引物组合及其应用
|