HK1130254A1 - Arylvinylazacycloalkane compounds and methods of preparation and use thereof - Google Patents

Arylvinylazacycloalkane compounds and methods of preparation and use thereof

Info

Publication number
HK1130254A1
HK1130254A1 HK09109159.9A HK09109159A HK1130254A1 HK 1130254 A1 HK1130254 A1 HK 1130254A1 HK 09109159 A HK09109159 A HK 09109159A HK 1130254 A1 HK1130254 A1 HK 1130254A1
Authority
HK
Hong Kong
Prior art keywords
preparation
methods
arylvinylazacycloalkane
compounds
arylvinylazacycloalkane compounds
Prior art date
Application number
HK09109159.9A
Other languages
English (en)
Inventor
Arielle Genevois-Borella
Craig Harrison Miller
Original Assignee
Targacept Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Targacept Inc filed Critical Targacept Inc
Publication of HK1130254A1 publication Critical patent/HK1130254A1/xx

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A—HUMAN NECESSITIES
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    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
HK09109159.9A 2003-03-05 2008-10-29 Arylvinylazacycloalkane compounds and methods of preparation and use thereof HK1130254A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/379,868 US7098331B2 (en) 2003-03-05 2003-03-05 Arylvinylazacycloalkane compounds and methods of preparation and use thereof
HK08111897.3A HK1116800A1 (en) 2003-03-05 2008-10-29 Arylvinylazacycloalkane compounds and methods of preparation and use thereof

Publications (1)

Publication Number Publication Date
HK1130254A1 true HK1130254A1 (en) 2009-12-24

Family

ID=32926772

Family Applications (3)

Application Number Title Priority Date Filing Date
HK06106130A HK1084949A1 (en) 2003-03-05 2006-05-26 Arylvinylazacycloalkane compounds and methods of preparation and use thereof
HK09109159.9A HK1130254A1 (en) 2003-03-05 2008-10-29 Arylvinylazacycloalkane compounds and methods of preparation and use thereof
HK08111897.3A HK1116800A1 (en) 2003-03-05 2008-10-29 Arylvinylazacycloalkane compounds and methods of preparation and use thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK06106130A HK1084949A1 (en) 2003-03-05 2006-05-26 Arylvinylazacycloalkane compounds and methods of preparation and use thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK08111897.3A HK1116800A1 (en) 2003-03-05 2008-10-29 Arylvinylazacycloalkane compounds and methods of preparation and use thereof

Country Status (32)

Country Link
US (8) US7098331B2 (xx)
EP (3) EP2085395B1 (xx)
JP (3) JP4663627B2 (xx)
KR (4) KR101185541B1 (xx)
CN (3) CN101255155A (xx)
AR (3) AR043469A1 (xx)
AT (3) ATE496046T1 (xx)
AU (3) AU2004217903B2 (xx)
BR (1) BRPI0409576A (xx)
CA (1) CA2516514C (xx)
CL (1) CL2004000452A1 (xx)
CY (2) CY1110391T1 (xx)
DE (2) DE602004013553D1 (xx)
DK (2) DK1601670T3 (xx)
EA (3) EA019240B1 (xx)
ES (3) ES2309507T3 (xx)
GT (1) GT200400033A (xx)
HK (3) HK1084949A1 (xx)
IL (3) IL170155A (xx)
JO (1) JO2488B1 (xx)
MX (1) MXPA05009386A (xx)
NO (3) NO331920B1 (xx)
NZ (1) NZ541795A (xx)
PA (1) PA8597201A1 (xx)
PE (1) PE20040930A1 (xx)
PL (5) PL1601670T3 (xx)
PT (2) PT2085395E (xx)
SI (2) SI2085395T1 (xx)
TW (3) TW200927746A (xx)
UY (1) UY28218A1 (xx)
WO (1) WO2004078752A1 (xx)
ZA (1) ZA200506790B (xx)

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TW200927745A (en) 2009-07-01
NO20091888L (no) 2005-10-03
UY28218A1 (es) 2005-06-30
AU2004217903A1 (en) 2004-09-16
EP2085395A1 (en) 2009-08-05
NO332293B1 (no) 2012-08-20
JO2488B1 (en) 2009-10-05
ATE517893T1 (de) 2011-08-15
US20110152293A1 (en) 2011-06-23
AR070570A2 (es) 2010-04-21
CN101550132B (zh) 2012-03-28
EP1947100A1 (en) 2008-07-23
US20060094732A1 (en) 2006-05-04
AU2004217903B2 (en) 2010-03-04
EP2085395B1 (en) 2011-01-19
EA010870B1 (ru) 2008-12-30
GT200400033A (es) 2005-05-29
US20100010042A1 (en) 2010-01-14
SI2085395T1 (sl) 2011-05-31
PT2085395E (pt) 2011-04-20
CN101550132A (zh) 2009-10-07
DK2085395T3 (da) 2011-04-18
KR20120014236A (ko) 2012-02-16
US7714001B2 (en) 2010-05-11
PA8597201A1 (es) 2004-09-28
CN1756754A (zh) 2006-04-05
PL394604A1 (pl) 2011-07-18
PL2085395T3 (pl) 2011-05-31
JP4663627B2 (ja) 2011-04-06
US20140107164A1 (en) 2014-04-17
PE20040930A1 (es) 2005-02-18
TWI377204B (en) 2012-11-21
IL170155A (en) 2013-08-29
EA019240B1 (ru) 2014-02-28
EA200501425A1 (ru) 2006-02-24
PL378415A1 (pl) 2006-04-03
JP2006519868A (ja) 2006-08-31
CA2516514C (en) 2012-02-07
US20080293778A1 (en) 2008-11-27
ATE394394T1 (de) 2008-05-15
NO331920B1 (no) 2012-04-30
US20150164894A1 (en) 2015-06-18
NO20092231L (no) 2005-10-03
DE602004013553D1 (de) 2008-06-19
KR20090021227A (ko) 2009-02-27
US8633222B2 (en) 2014-01-21
JP5537085B2 (ja) 2014-07-02
JP5537084B2 (ja) 2014-07-02
DK1601670T3 (da) 2008-08-25
BRPI0409576A (pt) 2006-04-18
ZA200506790B (en) 2006-05-31
CN100526308C (zh) 2009-08-12
IL197890A (en) 2013-11-28
PL215059B1 (pl) 2013-10-31
HK1116800A1 (en) 2009-01-02
PL216979B1 (pl) 2014-06-30
AR070569A2 (es) 2010-04-21
CY1110391T1 (el) 2015-04-29
AU2008258188A1 (en) 2009-01-15
PT1601670E (pt) 2008-07-11
TWI339662B (en) 2011-04-01
SI1601670T1 (sl) 2008-10-31
EP1601670B1 (en) 2008-05-07
EA200900706A1 (ru) 2009-10-30
AR043469A1 (es) 2005-07-27
KR20090021228A (ko) 2009-02-27
PL1601670T3 (pl) 2008-10-31
ES2389106T3 (es) 2012-10-23
IL197889A (en) 2013-03-24
JP2010001296A (ja) 2010-01-07
NO20054120L (no) 2005-10-03
US20100267776A1 (en) 2010-10-21
CA2516514A1 (en) 2004-09-16
DE602004031165D1 (de) 2011-03-03
US20040176348A1 (en) 2004-09-09
NO20054120D0 (no) 2005-09-05
KR100953150B1 (ko) 2010-04-19
EP1601670A1 (en) 2005-12-07
US8067443B2 (en) 2011-11-29
AU2008258187B2 (en) 2010-08-05
KR20060006006A (ko) 2006-01-18
TW200505909A (en) 2005-02-16
US8063068B2 (en) 2011-11-22
AU2008258188B2 (en) 2011-02-24
EP1947100B1 (en) 2011-07-27
JP2009292825A (ja) 2009-12-17
ES2385941T3 (es) 2012-08-03
CN101255155A (zh) 2008-09-03
CY1111615T1 (el) 2015-10-07
KR101185541B1 (ko) 2012-09-24
NZ541795A (en) 2008-03-28
CL2004000452A1 (es) 2005-05-20
MXPA05009386A (es) 2005-11-04
TW200927746A (en) 2009-07-01
HK1084949A1 (en) 2006-08-11
EA014714B1 (ru) 2011-02-28
KR101018083B1 (ko) 2011-03-02
US7098331B2 (en) 2006-08-29
PL394600A1 (pl) 2011-07-18
WO2004078752A1 (en) 2004-09-16
AU2008258187A1 (en) 2009-01-15
ES2309507T3 (es) 2008-12-16
EA200801764A1 (ru) 2008-12-30
ATE496046T1 (de) 2011-02-15

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