HK1068327A1 - Process for the preparation of (r)-or(s)-aminocarnitine inner salt, the salts and derivatives thereof - Google Patents
Process for the preparation of (r)-or(s)-aminocarnitine inner salt, the salts and derivatives thereofInfo
- Publication number
- HK1068327A1 HK1068327A1 HK05100341A HK05100341A HK1068327A1 HK 1068327 A1 HK1068327 A1 HK 1068327A1 HK 05100341 A HK05100341 A HK 05100341A HK 05100341 A HK05100341 A HK 05100341A HK 1068327 A1 HK1068327 A1 HK 1068327A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- aminocarnitine
- derivatives
- salts
- preparation
- inner salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
- C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
- C07C273/1827—X being H
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2001RM000456A ITRM20010456A1 (it) | 2001-07-26 | 2001-07-26 | Procedimento per la preparazione di (r)- o (s)- amminocarnitina sale interno, dei suoi sali e dei suoi derivati. |
PCT/IT2002/000468 WO2003010129A1 (en) | 2001-07-26 | 2002-07-17 | Process for the preparation of (r)- or (s)-aminocarnitine inner salt, the salts and derivatives thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1068327A1 true HK1068327A1 (en) | 2005-04-29 |
Family
ID=11455694
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05100341A HK1068327A1 (en) | 2001-07-26 | 2005-01-13 | Process for the preparation of (r)-or(s)-aminocarnitine inner salt, the salts and derivatives thereof |
Country Status (19)
Country | Link |
---|---|
US (1) | US6953865B2 (el) |
EP (1) | EP1409448B1 (el) |
JP (1) | JP4212473B2 (el) |
KR (1) | KR100879125B1 (el) |
CN (1) | CN1231460C (el) |
AT (1) | ATE346837T1 (el) |
AU (1) | AU2002330738B2 (el) |
CA (1) | CA2453019A1 (el) |
CY (1) | CY1107567T1 (el) |
DE (1) | DE60216466T2 (el) |
DK (1) | DK1409448T3 (el) |
ES (1) | ES2280570T3 (el) |
HK (1) | HK1068327A1 (el) |
HU (1) | HUP0401617A3 (el) |
IT (1) | ITRM20010456A1 (el) |
MX (1) | MXPA04000676A (el) |
PL (1) | PL367614A1 (el) |
PT (1) | PT1409448E (el) |
WO (1) | WO2003010129A1 (el) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1299266B1 (it) * | 1998-05-15 | 2000-02-29 | Sigma Tau Ind Farmaceuti | Inibitori reversibili della carnitina palmitoil trasferasi |
US7776915B2 (en) * | 2005-03-24 | 2010-08-17 | Tracie Martyn International, Llc | Topical formulations and methods of use |
US8410150B2 (en) | 2007-03-09 | 2013-04-02 | University Health Network | Inhibitors of carnitine palmitoyltransferase and treating cancer |
US8680282B2 (en) | 2007-08-01 | 2014-03-25 | University Health Network | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer |
CN111621541A (zh) * | 2019-02-27 | 2020-09-04 | 上海艾美晶生物科技有限公司 | 使用电渗析技术拆分光学异构体的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4767781A (en) * | 1981-11-26 | 1988-08-30 | Takeda Chemical Industries, Ltd. | Derivatives of beta-amino-gamma-trimethylammonio-butyrate and their production and use |
IT1261489B (it) * | 1993-07-29 | 1996-05-23 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di r amminocarnitina e s amminocarnitina. |
IT1299266B1 (it) * | 1998-05-15 | 2000-02-29 | Sigma Tau Ind Farmaceuti | Inibitori reversibili della carnitina palmitoil trasferasi |
IT1306184B1 (it) * | 1999-08-05 | 2001-05-30 | Sigma Tau Ind Farmaceuti | Nitrilossi derivati della (r) e (s)-carnitina. |
-
2001
- 2001-07-26 IT IT2001RM000456A patent/ITRM20010456A1/it unknown
-
2002
- 2002-07-17 AT AT02767834T patent/ATE346837T1/de not_active IP Right Cessation
- 2002-07-17 KR KR1020037017244A patent/KR100879125B1/ko not_active IP Right Cessation
- 2002-07-17 US US10/482,729 patent/US6953865B2/en not_active Expired - Fee Related
- 2002-07-17 CA CA002453019A patent/CA2453019A1/en not_active Abandoned
- 2002-07-17 CN CNB028140222A patent/CN1231460C/zh not_active Expired - Fee Related
- 2002-07-17 DE DE60216466T patent/DE60216466T2/de not_active Expired - Lifetime
- 2002-07-17 WO PCT/IT2002/000468 patent/WO2003010129A1/en active IP Right Grant
- 2002-07-17 PL PL02367614A patent/PL367614A1/xx unknown
- 2002-07-17 EP EP02767834A patent/EP1409448B1/en not_active Expired - Lifetime
- 2002-07-17 AU AU2002330738A patent/AU2002330738B2/en not_active Ceased
- 2002-07-17 DK DK02767834T patent/DK1409448T3/da active
- 2002-07-17 MX MXPA04000676A patent/MXPA04000676A/es active IP Right Grant
- 2002-07-17 PT PT02767834T patent/PT1409448E/pt unknown
- 2002-07-17 HU HU0401617A patent/HUP0401617A3/hu unknown
- 2002-07-17 ES ES02767834T patent/ES2280570T3/es not_active Expired - Lifetime
- 2002-07-17 JP JP2003515489A patent/JP4212473B2/ja not_active Expired - Fee Related
-
2005
- 2005-01-13 HK HK05100341A patent/HK1068327A1/xx not_active IP Right Cessation
-
2007
- 2007-02-26 CY CY20071100269T patent/CY1107567T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
MXPA04000676A (es) | 2004-04-05 |
KR100879125B1 (ko) | 2009-01-19 |
ITRM20010456A1 (it) | 2003-01-27 |
ATE346837T1 (de) | 2006-12-15 |
ITRM20010456A0 (it) | 2001-07-26 |
CN1527811A (zh) | 2004-09-08 |
CY1107567T1 (el) | 2013-03-13 |
AU2002330738B2 (en) | 2008-05-08 |
US20040171875A1 (en) | 2004-09-02 |
WO2003010129A1 (en) | 2003-02-06 |
CA2453019A1 (en) | 2003-02-06 |
PT1409448E (pt) | 2007-02-28 |
US6953865B2 (en) | 2005-10-11 |
PL367614A1 (en) | 2005-03-07 |
JP4212473B2 (ja) | 2009-01-21 |
DE60216466D1 (de) | 2007-01-11 |
EP1409448B1 (en) | 2006-11-29 |
EP1409448A1 (en) | 2004-04-21 |
JP2004536867A (ja) | 2004-12-09 |
ES2280570T3 (es) | 2007-09-16 |
DE60216466T2 (de) | 2007-09-20 |
CN1231460C (zh) | 2005-12-14 |
KR20040032116A (ko) | 2004-04-14 |
DK1409448T3 (da) | 2007-04-02 |
HUP0401617A3 (en) | 2008-05-28 |
HUP0401617A2 (hu) | 2004-12-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20110717 |