HK1055317A1 - Expression of biologically active polypeptides in duckweed - Google Patents
Expression of biologically active polypeptides in duckweedInfo
- Publication number
- HK1055317A1 HK1055317A1 HK03107543.4A HK03107543A HK1055317A1 HK 1055317 A1 HK1055317 A1 HK 1055317A1 HK 03107543 A HK03107543 A HK 03107543A HK 1055317 A1 HK1055317 A1 HK 1055317A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- duckweed
- expression
- biologically active
- active polypeptides
- polypeptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22170500P | 2000-07-31 | 2000-07-31 | |
US29333001P | 2001-05-23 | 2001-05-23 | |
PCT/US2001/023400 WO2002010414A2 (en) | 2000-07-31 | 2001-07-26 | Expression of biologically active polypeptides in duckweed |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1055317A1 true HK1055317A1 (en) | 2004-01-02 |
Family
ID=26916048
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK03107543.4A HK1055317A1 (en) | 2000-07-31 | 2003-10-17 | Expression of biologically active polypeptides in duckweed |
Country Status (14)
Country | Link |
---|---|
US (4) | US6815184B2 (xx) |
EP (1) | EP1305437B1 (xx) |
JP (1) | JP4795619B2 (xx) |
CN (2) | CN101676400A (xx) |
AT (1) | ATE479761T1 (xx) |
AU (2) | AU8822601A (xx) |
CA (1) | CA2417415C (xx) |
CY (1) | CY1110959T1 (xx) |
DE (1) | DE60142971D1 (xx) |
DK (1) | DK1305437T3 (xx) |
HK (1) | HK1055317A1 (xx) |
NZ (1) | NZ523912A (xx) |
PT (1) | PT1305437E (xx) |
WO (1) | WO2002010414A2 (xx) |
Families Citing this family (63)
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US20050032211A1 (en) * | 1996-09-26 | 2005-02-10 | Metabogal Ltd. | Cell/tissue culturing device, system and method |
IL155588A0 (en) * | 2003-04-27 | 2003-11-23 | Metabogal Ltd | Methods for expression of enzymatically active recombinant lysosomal enzymes in transgenic plant root cells and vectors used thereby |
US7161064B2 (en) * | 1997-08-12 | 2007-01-09 | North Carolina State University | Method for producing stably transformed duckweed using microprojectile bombardment |
AU4570397A (en) | 1997-10-10 | 1999-05-03 | Yeda Research And Development Co. Ltd. | Transgenic lemnaceae |
DE60142971D1 (de) * | 2000-07-31 | 2010-10-14 | Biolex Therapeutics Inc | Expression biologisch aktiver polypeptide in wasserlinse |
US7632983B2 (en) * | 2000-07-31 | 2009-12-15 | Biolex Therapeutics, Inc. | Expression of monoclonal antibodies in duckweed |
US8022270B2 (en) * | 2000-07-31 | 2011-09-20 | Biolex Therapeutics, Inc. | Expression of biologically active polypeptides in duckweed |
US7959910B2 (en) | 2000-07-31 | 2011-06-14 | Biolex Therapeutics, Inc. | C-terminally truncated interferon alpha variants |
US20030100945A1 (en) | 2001-11-23 | 2003-05-29 | Mindguard Ltd. | Implantable intraluminal device and method of using same in treating aneurysms |
DE60332358D1 (de) * | 2002-09-09 | 2010-06-10 | Hanall Pharmaceutical Co Ltd | Protease-resistente modifizierte interferon alpha polypeptide |
US20100196345A1 (en) * | 2003-04-27 | 2010-08-05 | Protalix | Production of high mannose proteins in plant culture |
US7951557B2 (en) * | 2003-04-27 | 2011-05-31 | Protalix Ltd. | Human lysosomal proteins from plant cell culture |
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AU2005212431B2 (en) * | 2004-02-11 | 2010-07-15 | Synthon Biopharmaceuticals B.V. | Expression of plasminogen and microplasminogen in duckweed |
US7527947B2 (en) | 2004-06-14 | 2009-05-05 | Novozymes A/S | Signal peptide for producing a polypeptide |
EP1756273B1 (en) * | 2004-06-14 | 2009-10-07 | Novozymes A/S | Signal peptide for producing a polypeptide |
US20060024272A1 (en) * | 2004-07-29 | 2006-02-02 | Large Scale Biology Corporation | C-terminally truncated interferon |
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CA2601858A1 (en) * | 2005-03-25 | 2006-09-28 | Glycart Biotechnology Ag | Antigen binding molecules directed to mcsp and having increased fc receptor binding affinity and effector function |
EP1888649A2 (en) * | 2005-05-09 | 2008-02-20 | GlycArt Biotechnology AG | Antigen binding molecules having modified fc regions and altered binding to fc receptors |
TWI615407B (zh) * | 2005-08-26 | 2018-02-21 | 羅齊克雷雅公司 | 具有經改變細胞傳訊活性之改質抗原結合分子 |
WO2007084672A2 (en) * | 2006-01-17 | 2007-07-26 | Medarex, Inc. | Monoclonal antibodies against cd30 lacking in fucosyl and xylosyl residues |
US7622573B2 (en) * | 2006-01-17 | 2009-11-24 | Biolex, Inc. | Expression control elements from the lemnaceae family |
AR062223A1 (es) * | 2006-08-09 | 2008-10-22 | Glycart Biotechnology Ag | Moleculas de adhesion al antigeno que se adhieren a egfr, vectores que los codifican, y sus usos de estas |
JP2010502220A (ja) | 2006-09-05 | 2010-01-28 | メダレックス インコーポレーティッド | 骨形態形成タンパク質およびその受容体に対する抗体ならびにその使用方法 |
PT2716301T (pt) | 2007-02-16 | 2017-07-04 | Merrimack Pharmaceuticals Inc | Anticorpos contra erbb3 e suas utilizações |
CA2685701C (en) | 2007-05-07 | 2019-01-15 | Protalix Ltd. | Large scale disposable bioreactor |
US8137661B2 (en) * | 2007-07-25 | 2012-03-20 | Biolex Therapeutics, Inc. | Controlled release interferon drug products and treatment of HCV infections using same |
JP5490714B2 (ja) | 2007-11-28 | 2014-05-14 | メディミューン,エルエルシー | タンパク質製剤 |
US8394384B2 (en) | 2008-11-28 | 2013-03-12 | Merial Limited | Recombinant avian influenza vaccine and uses thereof |
JP2012517829A (ja) * | 2009-02-18 | 2012-08-09 | バイオレックス・セラピューティクス インコーポレイテッド | 生体材料を処理するための無菌バイオリアクタ・システム |
WO2010138631A1 (en) | 2009-05-26 | 2010-12-02 | Biolex Therapeutics, Inc. | Compositions and methods for production of aglycosylated plasminogen |
US20120190004A1 (en) | 2009-06-23 | 2012-07-26 | Biolex Therapeutics, Inc. | Methods and compositions for the cryopreservation of duckweed |
MX339608B (es) | 2009-08-31 | 2016-05-31 | Roche Glycart Ag | Anticuerpos del antigeno carcinoembrionario (cea). |
US10633667B2 (en) | 2009-12-28 | 2020-04-28 | Boehringer Ingelheim Animal Health USA Inc. | Recombinant NDV antigen and uses thereof |
JP2013522300A (ja) | 2010-03-12 | 2013-06-13 | メリアル リミテッド | ***ウイルス組換えワクチンおよびその使用 |
WO2011140151A1 (en) | 2010-05-04 | 2011-11-10 | Dyax Corp. | Antibodies against epidermal growth factor receptor (egfr) |
WO2012009705A1 (en) | 2010-07-15 | 2012-01-19 | Zyngenia, Inc. | Ang-2 binding complexes and uses thereof |
US20140088019A1 (en) | 2011-02-11 | 2014-03-27 | Zyngenia, Inc. | Monovalent and Multivalent Multispecific Complexes and Uses Thereof |
UA115030C2 (uk) | 2011-03-02 | 2017-09-11 | Рош Глікарт Аг | Антитіло, яке зв'язується зі зв'язаним з мембраною карциноембріональним антигеном (сеа) |
ES2704038T3 (es) | 2011-05-24 | 2019-03-13 | Zyngenia Inc | Complejos multiespecíficos multivalentes y monovalentes y sus usos |
WO2013114371A1 (en) | 2012-02-01 | 2013-08-08 | Protalix Ltd. | Dry powder formulations of dnase i |
AR094432A1 (es) | 2012-04-05 | 2015-08-05 | Basf Plant Science Co Gmbh | Plantas resistentes a hongos que expresan hidrofobina |
BR112015021708A2 (pt) | 2013-03-06 | 2017-08-29 | Protalix Ltd | Inibidor de polipetídeo do tnfa, polinucleotídeo isolado, estrutura de expressão de ácido nucleico, célula de planta, composição farmacêutica e método de produção de um inibidor de polipeptídeo do tnfa |
BR112015021707A2 (pt) | 2013-03-06 | 2017-12-05 | Hadasit Med Res Service | uso de células de planta que expresam um inibidor de polipeptídeo tnfalfa em terapia. |
TWI463012B (zh) * | 2013-04-01 | 2014-12-01 | Lemnaceae Fermentation Inc | 浮萍水解物及其用途 |
EP3010939A2 (en) | 2013-06-17 | 2016-04-27 | Asana BioSciences, LLC | 5t4-targeted immunofusion molecule and methods |
WO2015027109A1 (en) | 2013-08-21 | 2015-02-26 | Cold Spring Harbor Laboratory | Transformation of duckweed and uses thereof |
CN103609304B (zh) * | 2013-11-22 | 2015-08-19 | 中国科学院成都生物研究所 | 一种快速提高浮萍淀粉含量的方法 |
MX2017012679A (es) | 2015-04-06 | 2018-02-09 | Subdomain Llc | Polipeptidos que contienen dominios de union de novo y usos de los mismos. |
PT3383920T (pt) | 2015-11-30 | 2024-04-15 | Univ California | Entrega de carga útil específica para tumores e ativação imune utilizando um anticorpo humano que tem como alvo um antigénio altamente específico da superfície das células tumorais |
JP2019517991A (ja) | 2016-03-01 | 2019-06-27 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 低減したadcpを有するオビヌツズマブ及びリツキシマブ変異体 |
IL245102A0 (en) | 2016-04-13 | 2016-07-31 | Yeda Res & Dev | Cultivation of wolffia plants |
BR112020009136A2 (pt) | 2017-11-14 | 2020-10-13 | Arcellx, Inc. | polipeptídeos que contêm domínio d e usos dos mesmos |
WO2019099440A1 (en) | 2017-11-14 | 2019-05-23 | Arcellx, Inc. | Multifunctional immune cell therapies |
CN116419747A (zh) | 2020-08-07 | 2023-07-11 | 福蒂斯治疗公司 | 靶向cd46的免疫偶联物及其使用方法 |
EP4228779A1 (en) | 2020-10-13 | 2023-08-23 | Avitide LLC | Aav8 affinity agents |
WO2022081779A1 (en) | 2020-10-13 | 2022-04-21 | Avitide LLC | Affinity ligand libraries of three-helix bundle proteins and uses thereof |
JP2024508587A (ja) | 2021-02-19 | 2024-02-28 | アヴィタイド エルエルシー | Aav2親和剤 |
WO2023122327A2 (en) | 2021-12-24 | 2023-06-29 | Avitide LLC | Chi domain affinity ligands and agents |
WO2024025911A1 (en) | 2022-07-29 | 2024-02-01 | Avitide LLC | An affinity agent comprising a ligand that binds vce and comprises seq id no: 1 |
WO2024054656A2 (en) | 2022-09-09 | 2024-03-14 | Avitide LLC | Affinity agents |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8315980D0 (en) | 1983-06-10 | 1983-07-13 | Biogen Nv | Producing hybrid dna sequences |
US4956282A (en) | 1985-07-29 | 1990-09-11 | Calgene, Inc. | Mammalian peptide expression in plant cells |
US5256410A (en) * | 1988-12-01 | 1993-10-26 | Schering Corporation | Treatment of squamous cell carcinoma intralesionally with recombinant human alpha interferon |
US5850032A (en) | 1992-04-01 | 1998-12-15 | Union Camp Corporation | Method for production of plant biological products in precocious neomorphic embryoids |
US6288302B1 (en) * | 1992-11-04 | 2001-09-11 | National Science Council Of R.O.C. | Application of α-amylase gene promoter and signal sequence in the production of recombinant proteins in transgenic plants and transgenic plant seeds |
US5569828A (en) | 1993-03-24 | 1996-10-29 | Pioneer Hi-Bred International, Inc. | Maize chlorotic dwarf virus and resistance thereto |
US5780709A (en) * | 1993-08-25 | 1998-07-14 | Dekalb Genetics Corporation | Transgenic maize with increased mannitol content |
US5693506A (en) | 1993-11-16 | 1997-12-02 | The Regents Of The University Of California | Process for protein production in plants |
US6020169A (en) | 1995-07-20 | 2000-02-01 | Washington State University Research Foundation | Production of secreted foreign polypeptides in plant cell culture |
US6066781A (en) | 1997-02-13 | 2000-05-23 | Applied Phytologics, Inc. | Production of mature proteins in plants |
WO1998036085A1 (en) | 1997-02-13 | 1998-08-20 | Applied Phytologics, Inc. | Production of mature proteins in plants |
ATE526818T1 (de) * | 1997-08-12 | 2011-10-15 | Univ North Carolina State | Gentechnisch hergestellte wasserlinse |
US6040498A (en) | 1998-08-11 | 2000-03-21 | North Caroline State University | Genetically engineered duckweed |
US7161064B2 (en) * | 1997-08-12 | 2007-01-09 | North Carolina State University | Method for producing stably transformed duckweed using microprojectile bombardment |
AU4570397A (en) | 1997-10-10 | 1999-05-03 | Yeda Research And Development Co. Ltd. | Transgenic lemnaceae |
US6095546A (en) * | 1997-12-03 | 2000-08-01 | Tekonsha Engineering Company | Trailer hitch cover and accessory components |
US6096546A (en) | 1998-01-30 | 2000-08-01 | Board Of Trustees, Rutgers, The State University Of New Jersey | Methods for recovering polypeptides from plants and portions thereof |
EP1064383A2 (en) * | 1998-03-19 | 2001-01-03 | Valentis Inc. | Interferon alpha plasmids and delivery systems, and methods of making and using the same |
DE60142971D1 (de) * | 2000-07-31 | 2010-10-14 | Biolex Therapeutics Inc | Expression biologisch aktiver polypeptide in wasserlinse |
-
2001
- 2001-07-26 DE DE60142971T patent/DE60142971D1/de not_active Expired - Lifetime
- 2001-07-26 AU AU8822601A patent/AU8822601A/xx active Pending
- 2001-07-26 WO PCT/US2001/023400 patent/WO2002010414A2/en active IP Right Grant
- 2001-07-26 CN CN200910174763A patent/CN101676400A/zh active Pending
- 2001-07-26 JP JP2002516330A patent/JP4795619B2/ja not_active Expired - Fee Related
- 2001-07-26 AT AT01967946T patent/ATE479761T1/de active
- 2001-07-26 CN CN01815064A patent/CN1451048A/zh active Pending
- 2001-07-26 PT PT01967946T patent/PT1305437E/pt unknown
- 2001-07-26 CA CA2417415A patent/CA2417415C/en not_active Expired - Fee Related
- 2001-07-26 EP EP01967946A patent/EP1305437B1/en not_active Expired - Lifetime
- 2001-07-26 US US09/915,873 patent/US6815184B2/en not_active Expired - Fee Related
- 2001-07-26 DK DK01967946.3T patent/DK1305437T3/da active
- 2001-07-26 AU AU2001288226A patent/AU2001288226B2/en not_active Ceased
- 2001-07-26 NZ NZ523912A patent/NZ523912A/en not_active IP Right Cessation
-
2003
- 2003-10-17 HK HK03107543.4A patent/HK1055317A1/xx unknown
-
2004
- 2004-06-22 US US10/873,846 patent/US20050060776A1/en not_active Abandoned
-
2007
- 2007-07-16 US US11/778,480 patent/US20090282584A1/en not_active Abandoned
-
2010
- 2010-11-30 CY CY20101101098T patent/CY1110959T1/el unknown
-
2011
- 2011-09-14 US US13/232,602 patent/US20120258491A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US6815184B2 (en) | 2004-11-09 |
CA2417415A1 (en) | 2002-02-07 |
US20120258491A1 (en) | 2012-10-11 |
CN101676400A (zh) | 2010-03-24 |
US20090282584A1 (en) | 2009-11-12 |
US20050060776A1 (en) | 2005-03-17 |
US20020088027A1 (en) | 2002-07-04 |
ATE479761T1 (de) | 2010-09-15 |
AU8822601A (en) | 2002-02-13 |
WO2002010414A3 (en) | 2002-12-27 |
WO2002010414A9 (en) | 2003-10-30 |
JP4795619B2 (ja) | 2011-10-19 |
JP2004504848A (ja) | 2004-02-19 |
NZ523912A (en) | 2005-03-24 |
CA2417415C (en) | 2012-10-09 |
CY1110959T1 (el) | 2015-06-11 |
DE60142971D1 (de) | 2010-10-14 |
CN1451048A (zh) | 2003-10-22 |
EP1305437B1 (en) | 2010-09-01 |
EP1305437A2 (en) | 2003-05-02 |
AU2001288226B2 (en) | 2007-07-26 |
PT1305437E (pt) | 2010-11-12 |
DK1305437T3 (da) | 2010-12-13 |
WO2002010414A2 (en) | 2002-02-07 |
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