HK1032050A1 - Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas. - Google Patents

Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas.

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Publication number
HK1032050A1
HK1032050A1 HK01102468A HK01102468A HK1032050A1 HK 1032050 A1 HK1032050 A1 HK 1032050A1 HK 01102468 A HK01102468 A HK 01102468A HK 01102468 A HK01102468 A HK 01102468A HK 1032050 A1 HK1032050 A1 HK 1032050A1
Authority
HK
Hong Kong
Prior art keywords
kinase
inhibition
symmetrical
diphenyl ureas
unsymmetrical diphenyl
Prior art date
Application number
HK01102468A
Other languages
English (en)
Inventor
Scott Miller
Martin Osterhout
Jacques Dumas
Uday Khire
Timothy Bruno Lowinger
Bernd Riedl
William J Scott
Roger A Smith
Jill E Wood
David Gunn
Holia Hatoum-Mokdad
Mareli Rodriguez
Robert Sibley
Ming Wang
Tiffany Turner
Catherine Brennan
Original Assignee
Bayer Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25542166&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1032050(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Pharmaceuticals Corp filed Critical Bayer Pharmaceuticals Corp
Publication of HK1032050A1 publication Critical patent/HK1032050A1/xx

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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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HK01102468A 1997-12-22 2001-04-07 Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas. HK1032050A1 (en)

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