HK1016177A1 - New 4-(oxyalkoxyphenyl)-3-oxy-piperidines for treating heart and kidney insufficiency - Google Patents
New 4-(oxyalkoxyphenyl)-3-oxy-piperidines for treating heart and kidney insufficiencyInfo
- Publication number
- HK1016177A1 HK1016177A1 HK99101299A HK99101299A HK1016177A1 HK 1016177 A1 HK1016177 A1 HK 1016177A1 HK 99101299 A HK99101299 A HK 99101299A HK 99101299 A HK99101299 A HK 99101299A HK 1016177 A1 HK1016177 A1 HK 1016177A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- oxyalkoxyphenyl
- piperidines
- oxy
- new
- treating heart
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH254895 | 1995-09-07 | ||
CH187696 | 1996-07-26 | ||
PCT/EP1996/003803 WO1997009311A1 (fr) | 1995-09-07 | 1996-08-29 | Nouvelles 4-(oxyalcoxyphenyl)-3-oxy-piperidines utiles pour traiter l'insuffisance cardiaque et renale |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1016177A1 true HK1016177A1 (en) | 1999-10-29 |
Family
ID=25688898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK99101299A HK1016177A1 (en) | 1995-09-07 | 1999-03-30 | New 4-(oxyalkoxyphenyl)-3-oxy-piperidines for treating heart and kidney insufficiency |
Country Status (27)
Country | Link |
---|---|
US (2) | US6051712A (fr) |
EP (1) | EP0863875B1 (fr) |
JP (1) | JP3648251B2 (fr) |
KR (1) | KR100384979B1 (fr) |
CN (1) | CN1256326C (fr) |
AT (1) | ATE242213T1 (fr) |
BR (1) | BR9610385A (fr) |
CA (1) | CA2230931C (fr) |
CY (1) | CY2488B1 (fr) |
CZ (1) | CZ292327B6 (fr) |
DE (1) | DE59610509D1 (fr) |
DK (1) | DK0863875T3 (fr) |
ES (1) | ES2201192T3 (fr) |
HK (1) | HK1016177A1 (fr) |
HU (1) | HUP9900926A3 (fr) |
IL (1) | IL123293A (fr) |
MA (1) | MA23967A1 (fr) |
MY (1) | MY121967A (fr) |
NO (1) | NO310069B1 (fr) |
NZ (1) | NZ315677A (fr) |
PL (1) | PL193686B1 (fr) |
PT (1) | PT863875E (fr) |
RU (1) | RU2167865C2 (fr) |
SA (1) | SA96170317B1 (fr) |
TR (1) | TR199800409T1 (fr) |
TW (1) | TW474932B (fr) |
WO (1) | WO1997009311A1 (fr) |
Families Citing this family (91)
Publication number | Priority date | Publication date | Assignee | Title |
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HU221921B1 (hu) * | 1996-07-08 | 2003-02-28 | Richter Gedeon Vegyészeti Gyár Rt. | N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására |
JP2001525812A (ja) | 1997-05-14 | 2001-12-11 | ニューロサーアチ・アクティーゼルスカブ | 神経伝達物質再吸収阻害剤としてのピペリジン誘導体 |
HUP0003958A3 (en) | 1997-05-29 | 2001-06-28 | Smithkline Beecham Plc | Process for preparation of 4-aryl-piperidines and intermediates |
WO1999012532A2 (fr) * | 1997-09-08 | 1999-03-18 | F.Hoffmann-La Roche Ag | Derives de piperidine contre la malaria |
TR200002904T2 (tr) | 1998-04-10 | 2001-02-21 | Japan Tobacco Inc. | Amidin bileşikleri |
US6268499B1 (en) * | 1998-08-10 | 2001-07-31 | Hoffman-La Roche Inc. | Process and intermediates for preparation of substituted piperidine-epoxides |
US6274735B1 (en) | 1998-08-10 | 2001-08-14 | Hoffmann-La Roche Inc. | Process and intermediates for preparation of substituted piperidines |
WO2000063173A1 (fr) * | 1999-04-14 | 2000-10-26 | F. Hoffmann-La Roche Ag | Procede de preparation de piperidines substituees |
US6197959B1 (en) * | 1999-04-27 | 2001-03-06 | Hoffmann-La Roche Inc. | Piperidine derivatives |
US6376672B1 (en) * | 1999-04-27 | 2002-04-23 | Hoffmann-La Roche Inc. | Naphthalenylmethoxypiperidines as renin inhibitors |
IT1313702B1 (it) * | 1999-08-02 | 2002-09-09 | Chemi Spa | Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piperidine. |
CA2383524C (fr) * | 1999-08-31 | 2010-09-28 | Merck & Co., Inc. | Composes heterocycliques et procedes d'utilisation de ceux-ci |
RU2257382C2 (ru) * | 1999-10-15 | 2005-07-27 | Ф.Хоффманн-Ля Рош Аг | Производные бензодиазепина, лекарственное средство, содержащее их, и способ их получения |
DE60113104D1 (de) * | 2000-06-13 | 2005-10-06 | Basf Ag | 5 phenyl substituierte 2-(cyanoamino)-pyrimidine als fungizide |
US20060079533A1 (en) * | 2001-03-23 | 2006-04-13 | Nieman James A | Methods of treating alzheimer's disease |
OA12812A (en) * | 2001-11-19 | 2006-07-10 | Elan Pharm Inc | (4-phenyl) Piperidin-3-yl-phenylcarboxylate derovatoves and related compounds as beta-secretase inhibitors for the treatment of Alzheimer's Disease. |
BR0309498A (pt) * | 2002-04-29 | 2005-02-15 | Actelion Pharmaceuticals Ltd | Compostos, composições farmacêuticas, método para o tratamento ou profilaxia de doenças que são relacionadas com o ras, e, uso de compostos |
AU2003229746A1 (en) * | 2002-06-27 | 2004-01-19 | Actelion Pharmaceuticals Ltd | Novel tetrahydropyridine derivatives as renin inhibitors |
JP2006519229A (ja) | 2003-02-13 | 2006-08-24 | アルバート・アインシュタイン・カレッジ・オヴ・メディシン・オヴ・イェシヴァ・ユニヴァーシティ | 視床下部内の長鎖脂肪アシルCoAレベルの変調による摂食量およびグルコース産生量の調節 |
US20040204455A1 (en) * | 2003-04-10 | 2004-10-14 | Cody Wayne Livingston | Piperidine derivative rennin inhibitors |
US20040214832A1 (en) * | 2003-04-10 | 2004-10-28 | Cuiman Cai | Piperazine derivative renin inhibitors |
CN1780836A (zh) * | 2003-04-28 | 2006-05-31 | 埃科特莱茵药品有限公司 | 作为血管紧张肽原酶抑制剂的新型二氮杂双环壬烯和四氢吡啶衍生物 |
BRPI0409881A (pt) * | 2003-04-29 | 2006-05-23 | Actelion Pharmaceuticals Ltd | compostos, composições farmacêuticas, método para o tratamento ou profilaxia de doenças, e, usos de compostos e de um ou mais compostos em combinação com outros compostos farmacologicamente ativos |
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CN1856484B (zh) | 2003-07-24 | 2010-09-22 | 欧洲凯尔蒂克公司 | 用于治疗或预防疼痛的杂芳基-四氢吡啶基化合物 |
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JP4750712B2 (ja) * | 2003-11-26 | 2011-08-17 | ノバルティス アーゲー | レニン阻害剤としての4−フェニルピペリジン誘導体 |
JP2007529459A (ja) | 2004-03-17 | 2007-10-25 | ノバルティス アクチエンゲゼルシャフト | 治療に置けるレニン阻害剤の使用 |
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AR069145A1 (es) * | 2007-11-02 | 2009-12-30 | Speedel Experimenta Ag | Piperidinas 4,4- disusutituidas, uso del compuesto en la produccion de un medicamento, un producto farmaceutico en base al compuesto y un metodo de prevencion de enfermedades |
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MY152042A (en) | 2008-05-05 | 2014-08-15 | Actelion Pharmaceuticals Ltd | 3,4- substituted piperidine derivatives as renin inhibitors |
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DE1545792B2 (de) * | 1965-02-27 | 1975-08-07 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von 4-Hydroxyplperidinen |
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