GT201500267A - Anticuerpos anti-cd52 - Google Patents
Anticuerpos anti-cd52Info
- Publication number
- GT201500267A GT201500267A GT201500267A GT201500267A GT201500267A GT 201500267 A GT201500267 A GT 201500267A GT 201500267 A GT201500267 A GT 201500267A GT 201500267 A GT201500267 A GT 201500267A GT 201500267 A GT201500267 A GT 201500267A
- Authority
- GT
- Guatemala
- Prior art keywords
- antibodies
- fragments
- hospeding
- rejection
- union
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2893—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD52
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Abstract
LA PRESENTE INVENCIÓN DESCRIBE ANTICUERPOS ANTI-CD52 HUMANA Y FRAGMENTOS DE UNIÓN A ANTÍGENO DE LOS MISMOS. TAMBIÉN SE PROPORCIONAN ÁCIDOS NUCLEICOS AISLADOS, VECTORES RECOMBINANTES Y CÉLULAS HOSPEDANTES PARA PREPARAR LOS ANTICUERPOS Y FRAGMENTOS. LOS ANTICUERPOS Y FRAGMENTOS SE PUEDEN USAR EN APLICACIONES TERAPÉUTICAS PARA TRATAR, POR EJEMPLO, ENFERMEDADES AUTOINMUNES, CÁNCER Y RECHAZO DE INJERTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361794576P | 2013-03-15 | 2013-03-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
GT201500267A true GT201500267A (es) | 2017-12-15 |
Family
ID=50391542
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT201500267A GT201500267A (es) | 2013-03-15 | 2015-09-09 | Anticuerpos anti-cd52 |
Country Status (36)
Country | Link |
---|---|
US (2) | US9708407B2 (es) |
EP (1) | EP2970467B1 (es) |
JP (2) | JP6482524B2 (es) |
KR (1) | KR20150131286A (es) |
CN (1) | CN105209495B (es) |
AR (1) | AR095199A1 (es) |
AU (1) | AU2014233685B2 (es) |
BR (1) | BR112015022464A2 (es) |
CA (1) | CA2906539A1 (es) |
CL (1) | CL2015002705A1 (es) |
CR (1) | CR20150547A (es) |
CY (1) | CY1121795T1 (es) |
DK (1) | DK2970467T3 (es) |
DO (1) | DOP2015000211A (es) |
EA (1) | EA031730B1 (es) |
ES (1) | ES2710976T3 (es) |
GT (1) | GT201500267A (es) |
HK (1) | HK1219963A1 (es) |
HR (1) | HRP20190085T1 (es) |
HU (1) | HUE041796T2 (es) |
IL (1) | IL241410A0 (es) |
LT (1) | LT2970467T (es) |
MA (1) | MA38485A1 (es) |
MX (1) | MX2015012991A (es) |
NZ (1) | NZ631473A (es) |
PE (1) | PE20151757A1 (es) |
PH (1) | PH12015501932A1 (es) |
PL (1) | PL2970467T4 (es) |
PT (1) | PT2970467T (es) |
SG (1) | SG11201506932SA (es) |
SI (1) | SI2970467T1 (es) |
TN (1) | TN2015000415A1 (es) |
TR (1) | TR201900638T4 (es) |
TW (1) | TWI644923B (es) |
UY (1) | UY35440A (es) |
WO (1) | WO2014151644A2 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2429582A4 (en) | 2009-05-13 | 2013-01-23 | Genzyme Corp | IMMUNOGLOBULINS ANTI-CD52 HUMAN |
MX342907B (es) | 2009-05-13 | 2016-10-17 | Genzyme Corp * | El uso de un anticuerpo anti-cd52 monoclonal para el tratamiento de lupus. |
PL3079322T3 (pl) * | 2014-01-28 | 2021-01-11 | Huawei Technologies Co., Ltd. | Sposób wskazywania transmisji danych, punkt dostępowy i terminal |
EP3612564A2 (en) * | 2017-04-21 | 2020-02-26 | Genzyme Corporation | Treatment of multiple sclerosis with anti-cd52 antibodies |
MX2020008446A (es) * | 2018-02-13 | 2020-09-28 | Merck Sharp & Dohme | Metodos para el tratamiento contra el cancer mediante anticuerpos anti-pd-1 y anticuerpos anti-ctla4. |
US20220288118A1 (en) * | 2019-07-31 | 2022-09-15 | Forty Seven, Inc. | Depletion regimes for engineered t-cell or nk-cell therapy |
WO2024038839A1 (ja) * | 2022-08-15 | 2024-02-22 | 国立大学法人 東京大学 | 糸状菌を用いた免疫グロブリンまたは多量体免疫グロブリンの製造方法 |
Family Cites Families (65)
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GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
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US6054561A (en) | 1984-02-08 | 2000-04-25 | Chiron Corporation | Antigen-binding sites of antibody molecules specific for cancer antigens |
GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
US4970198A (en) | 1985-10-17 | 1990-11-13 | American Cyanamid Company | Antitumor antibiotics (LL-E33288 complex) |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
WO1987006265A1 (en) | 1986-04-17 | 1987-10-22 | Kyowa Hakko Kogyo Co., Ltd. | Novel compounds dc-88a and dc-89a1 and process for their preparation |
EP0307434B2 (en) | 1987-03-18 | 1998-07-29 | Scotgen Biopharmaceuticals, Inc. | Altered antibodies |
WO1989007142A1 (en) | 1988-02-05 | 1989-08-10 | Morrison Sherie L | Domain-modified constant region antibodies |
JP2598116B2 (ja) | 1988-12-28 | 1997-04-09 | 協和醗酵工業株式会社 | 新規物質dc113 |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5187186A (en) | 1989-07-03 | 1993-02-16 | Kyowa Hakko Kogyo Co., Ltd. | Pyrroloindole derivatives |
JP2510335B2 (ja) | 1989-07-03 | 1996-06-26 | 協和醗酵工業株式会社 | Dc―88a誘導体 |
US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
ES2246502T3 (es) | 1990-08-29 | 2006-02-16 | Genpharm International, Inc. | Animales no humanos transgenicos capaces de producir anticuerpos heterologos. |
GB9022547D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Purified immunoglobulin |
GB9022543D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Antibody production |
GB9108056D0 (en) | 1991-04-16 | 1991-06-05 | Hale Geoffrey | Synthetic antigen |
EP0519596B1 (en) | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | A method for reducing the immunogenicity of antibody variable domains |
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US5264586A (en) | 1991-07-17 | 1993-11-23 | The Scripps Research Institute | Analogs of calicheamicin gamma1I, method of making and using the same |
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JP2009521909A (ja) | 2005-12-30 | 2009-06-11 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | IL−6とIL−6Rαの複合体のgp130への結合を阻害する抗IL−6抗体 |
ES2547333T3 (es) | 2006-04-12 | 2015-10-05 | Genzyme Corporation | Métodos para tratar enfermedades autoinmunes |
EP2433649A3 (en) | 2006-09-13 | 2012-10-31 | Alcafleu Management GmbH & Co. KG | Treatment of multiple sclerosis (MS) with campath-1H |
US9498528B2 (en) | 2006-09-13 | 2016-11-22 | Genzyme Corporation | Treatment of multiple sclerosis (MS) |
CA2679400A1 (en) * | 2007-02-28 | 2008-09-04 | Schering Corporation | Combination therapy for treatment of immune disorders |
EP2160408A1 (en) | 2007-06-22 | 2010-03-10 | Bayer Schering Pharma Aktiengesellschaft | Use of antibodies against the cd52 antigen for the treatment of neurological disorders, particularly transmissible spongiform encephalopathy and alzheimer's disease |
EP2429582A4 (en) * | 2009-05-13 | 2013-01-23 | Genzyme Corp | IMMUNOGLOBULINS ANTI-CD52 HUMAN |
EP2429584A4 (en) | 2009-05-13 | 2013-02-20 | Genzyme Corp | TREATMENT PROCEDURE AND COMPOSITIONS |
MX342907B (es) | 2009-05-13 | 2016-10-17 | Genzyme Corp * | El uso de un anticuerpo anti-cd52 monoclonal para el tratamiento de lupus. |
AR077756A1 (es) * | 2009-07-15 | 2011-09-21 | Genentech Inc | Anticuerpos especificos para bacterias gram-positivas |
EP4219805A1 (en) * | 2010-07-16 | 2023-08-02 | Adimab, LLC | Antibody libraries |
-
2014
- 2014-03-10 AR ARP140100806A patent/AR095199A1/es unknown
- 2014-03-13 HU HUE14714135A patent/HUE041796T2/hu unknown
- 2014-03-13 EA EA201591796A patent/EA031730B1/ru not_active IP Right Cessation
- 2014-03-13 PE PE2015001992A patent/PE20151757A1/es not_active Application Discontinuation
- 2014-03-13 PL PL14714135T patent/PL2970467T4/pl unknown
- 2014-03-13 PT PT14714135T patent/PT2970467T/pt unknown
- 2014-03-13 DK DK14714135.2T patent/DK2970467T3/en active
- 2014-03-13 JP JP2016502067A patent/JP6482524B2/ja not_active Expired - Fee Related
- 2014-03-13 US US14/774,911 patent/US9708407B2/en active Active
- 2014-03-13 LT LTEP14714135.2T patent/LT2970467T/lt unknown
- 2014-03-13 SI SI201431047T patent/SI2970467T1/sl unknown
- 2014-03-13 CN CN201480028098.XA patent/CN105209495B/zh not_active Expired - Fee Related
- 2014-03-13 TW TW103108914A patent/TWI644923B/zh not_active IP Right Cessation
- 2014-03-13 NZ NZ631473A patent/NZ631473A/en not_active IP Right Cessation
- 2014-03-13 SG SG11201506932SA patent/SG11201506932SA/en unknown
- 2014-03-13 AU AU2014233685A patent/AU2014233685B2/en not_active Ceased
- 2014-03-13 BR BR112015022464A patent/BR112015022464A2/pt not_active Application Discontinuation
- 2014-03-13 EP EP14714135.2A patent/EP2970467B1/en active Active
- 2014-03-13 ES ES14714135T patent/ES2710976T3/es active Active
- 2014-03-13 CA CA2906539A patent/CA2906539A1/en not_active Abandoned
- 2014-03-13 MX MX2015012991A patent/MX2015012991A/es unknown
- 2014-03-13 MA MA38485A patent/MA38485A1/fr unknown
- 2014-03-13 WO PCT/US2014/026159 patent/WO2014151644A2/en active Application Filing
- 2014-03-13 TR TR2019/00638T patent/TR201900638T4/tr unknown
- 2014-03-13 KR KR1020157029345A patent/KR20150131286A/ko not_active Application Discontinuation
- 2014-03-14 UY UY0001035440A patent/UY35440A/es not_active Application Discontinuation
-
2015
- 2015-08-31 DO DO2015000211A patent/DOP2015000211A/es unknown
- 2015-09-02 PH PH12015501932A patent/PH12015501932A1/en unknown
- 2015-09-09 IL IL241410A patent/IL241410A0/en unknown
- 2015-09-09 GT GT201500267A patent/GT201500267A/es unknown
- 2015-09-11 TN TN2015000415A patent/TN2015000415A1/en unknown
- 2015-09-14 CL CL2015002705A patent/CL2015002705A1/es unknown
- 2015-10-13 CR CR20150547A patent/CR20150547A/es unknown
-
2016
- 2016-07-11 HK HK16108030.7A patent/HK1219963A1/zh not_active IP Right Cessation
-
2017
- 2017-06-16 US US15/625,361 patent/US20170349665A1/en not_active Abandoned
-
2018
- 2018-12-07 JP JP2018229547A patent/JP2019069960A/ja active Pending
-
2019
- 2019-01-15 HR HRP20190085TT patent/HRP20190085T1/hr unknown
- 2019-01-17 CY CY20191100066T patent/CY1121795T1/el unknown
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