GR72953B - - Google Patents

Info

Publication number
GR72953B
GR72953B GR59168A GR790159168A GR72953B GR 72953 B GR72953 B GR 72953B GR 59168 A GR59168 A GR 59168A GR 790159168 A GR790159168 A GR 790159168A GR 72953 B GR72953 B GR 72953B
Authority
GR
Greece
Prior art keywords
cleaved
gene
protein
selected protein
periplasmic
Prior art date
Application number
GR59168A
Other languages
English (en)
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25433372&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR72953(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Harvard College filed Critical Harvard College
Publication of GR72953B publication Critical patent/GR72953B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/034—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the periplasmic space of Gram negative bacteria as a soluble protein, i.e. signal sequence should be cleaved
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
GR59168A 1978-06-08 1979-05-24 GR72953B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/913,533 US4411994A (en) 1978-06-08 1978-06-08 Protein synthesis

Publications (1)

Publication Number Publication Date
GR72953B true GR72953B (el) 1984-01-18

Family

ID=25433372

Family Applications (1)

Application Number Title Priority Date Filing Date
GR59168A GR72953B (el) 1978-06-08 1979-05-24

Country Status (20)

Country Link
US (1) US4411994A (el)
EP (1) EP0006694B2 (el)
JP (2) JPS5519092A (el)
AT (1) ATE5001T1 (el)
AU (1) AU524856B2 (el)
BG (1) BG60444B2 (el)
CA (1) CA1215920A (el)
DD (1) DD148235A5 (el)
DE (1) DE2966291D1 (el)
DK (1) DK237979A (el)
ES (1) ES481362A1 (el)
FI (1) FI791841A (el)
GR (1) GR72953B (el)
IE (1) IE48156B1 (el)
IL (1) IL57491A (el)
MX (1) MX6339E (el)
NZ (1) NZ190524A (el)
PT (1) PT69737A (el)
WO (1) WO1980000030A1 (el)
ZA (1) ZA792486B (el)

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US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
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DE3001928A1 (de) * 1980-01-19 1981-08-06 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
US6455275B1 (en) 1980-02-25 2002-09-24 The Trustees Of Columbia University In The City Of New York DNA construct for producing proteinaceous materials in eucaryotic cells
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US4711843A (en) * 1980-12-31 1987-12-08 Cetus Corporation Method and vector organism for controlled accumulation of cloned heterologous gene products in Bacillus subtilis
ATE56471T1 (de) 1980-04-03 1990-09-15 Biogen Inc Dns-sequenzen, rekombinante dns-molekuele und verfahren zur herstellung von dem menschlichen fibroblast-interferon.
US4338397A (en) * 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
US6610830B1 (en) 1980-07-01 2003-08-26 Hoffman-La Roche Inc. Microbial production of mature human leukocyte interferons
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US4394443A (en) * 1980-12-18 1983-07-19 Yale University Method for cloning genes
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US4663285A (en) * 1981-01-06 1987-05-05 The Public Health Laboratory Service Board Chimeric plasmids
ZA824218B (en) * 1981-06-29 1983-04-27 Cetus Corp Plasmid for producing human insulin
JPS5869897A (ja) * 1981-10-20 1983-04-26 Gakuzo Tamura Ｄｎａ遺伝子
EP0078154A3 (en) * 1981-10-28 1985-01-09 The Regents Of The University Of California Plasmids and cells for heterologous expression of metallothioneins and processes for producing and using the metallothionein
US4532207A (en) * 1982-03-19 1985-07-30 G. D. Searle & Co. Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase
US4863855A (en) * 1982-05-14 1989-09-05 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
JPS592689A (ja) * 1982-06-04 1984-01-09 Handai Biseibutsubiyou Kenkyukai 強力な遺伝子発現能を有する新規レプリコンの作成法
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US4962055A (en) * 1983-03-08 1990-10-09 Rikagaku Kenkyusho Plasmid, method for construction of the same, microorganisms carrying the plasmid and method for cultivation of the microorganism
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US4695542A (en) 1983-10-04 1987-09-22 Dnax Research Institute Of Molecular And Cellular Biology, Inc. cDNA clones coding for polypeptides exhibiting multi-lineage cellular growth factor activity
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AU2021260878A1 (en) 2020-04-20 2022-11-17 Vestaron Corporation Proteolytically stable U1-agatoxin-Ta1b variant polypeptides for pest control
TW202205956A (zh) 2020-05-01 2022-02-16 美商韋斯塔隆公司 殺蟲組合
IL301655A (en) 2020-09-28 2023-05-01 Vestaron Corp MU-Digotoxin-DC1A variant polypeptides for pest control
WO2022212863A1 (en) 2021-04-01 2022-10-06 Vestaron Corporation Liposome formulations for pesticide delivery and methods for producing and using the same
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CA3238619A1 (en) 2021-11-29 2023-06-01 Michael Gerber Pharmaceutical compositions for the treatment of visceral pain
WO2023192924A1 (en) 2022-03-30 2023-10-05 Vestaron Corporation Combinations of av3 mutant polypeptides and bt toxins for pest control
TW202413392A (zh) 2022-05-18 2024-04-01 美商韋斯塔隆公司 殺蟲ａｃｔｘ肽變異體
WO2023245100A1 (en) 2022-06-17 2023-12-21 Vestaron Corporation Antimicrobial ncr13 variant peptides
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Also Published As

Publication number Publication date
AU524856B2 (en) 1982-10-07
MX6339E (es) 1985-04-23
WO1980000030A1 (en) 1980-01-10
IE791115L (en) 1979-12-08
IL57491A (en) 1983-09-30
EP0006694A3 (en) 1980-01-23
EP0006694B2 (en) 1992-01-22
EP0006694B1 (en) 1983-10-12
DE2966291D1 (en) 1983-11-17
BG60444B2 (bg) 1995-03-31
DD148235A5 (de) 1981-05-13
CA1215920A (en) 1986-12-30
JPS6246160B2 (el) 1987-09-30
JPS5519092A (en) 1980-02-09
AU4775279A (en) 1979-12-13
EP0006694A2 (en) 1980-01-09
NZ190524A (en) 1982-09-14
ZA792486B (en) 1981-01-28
US4411994A (en) 1983-10-25
JPS61227598A (ja) 1986-10-09
PT69737A (en) 1979-07-01
ATE5001T1 (de) 1983-10-15
IE48156B1 (en) 1984-10-17
DK237979A (da) 1979-12-09
JPH0755151B2 (ja) 1995-06-14
FI791841A (fi) 1979-12-09
IL57491A0 (en) 1979-10-31
ES481362A1 (es) 1980-03-01

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