GB1477999A - Method of producing 2-substituted 1,4-benzodiazepine derivatives - Google Patents

Method of producing 2-substituted 1,4-benzodiazepine derivatives

Info

Publication number
GB1477999A
GB1477999A GB1919676A GB1919676A GB1477999A GB 1477999 A GB1477999 A GB 1477999A GB 1919676 A GB1919676 A GB 1919676A GB 1919676 A GB1919676 A GB 1919676A GB 1477999 A GB1477999 A GB 1477999A
Authority
GB
United Kingdom
Prior art keywords
compounds
alkali metal
hydrogen atom
mixture
isomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1919676A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kali Chemie AG
Original Assignee
Kali Chemie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie AG filed Critical Kali Chemie AG
Publication of GB1477999A publication Critical patent/GB1477999A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • C07D245/04—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D245/06—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB1919676A 1975-05-10 1976-05-10 Method of producing 2-substituted 1,4-benzodiazepine derivatives Expired GB1477999A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2520937A DE2520937C3 (de) 1975-05-10 1975-05-10 7-Brom-1 -methyl^-alkoxymethyl-S-(2-halogenphenyl)-lH-23-dihydro-l,4benzodiazepinderivate, deren Säureadditionssalze und pharmazeutische Präparate

Publications (1)

Publication Number Publication Date
GB1477999A true GB1477999A (en) 1977-06-29

Family

ID=5946275

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1919676A Expired GB1477999A (en) 1975-05-10 1976-05-10 Method of producing 2-substituted 1,4-benzodiazepine derivatives

Country Status (28)

Country Link
JP (2) JPS51149293A (zh)
AR (1) AR209361A1 (zh)
AT (1) AT353274B (zh)
AU (1) AU498994B2 (zh)
BE (1) BE841549A (zh)
CA (1) CA1063107A (zh)
CH (1) CH626076A5 (zh)
CS (1) CS193075B2 (zh)
DD (1) DD124600A5 (zh)
DE (1) DE2520937C3 (zh)
DK (1) DK145930C (zh)
ES (1) ES447737A1 (zh)
FI (2) FI62072C (zh)
FR (1) FR2310765A1 (zh)
GB (1) GB1477999A (zh)
GR (1) GR60311B (zh)
HU (1) HU174020B (zh)
IL (1) IL49548A (zh)
MX (1) MX3903E (zh)
NL (1) NL187631C (zh)
NO (1) NO146238C (zh)
NZ (1) NZ180812A (zh)
PH (1) PH14964A (zh)
PT (1) PT65083B (zh)
SE (1) SE422938B (zh)
SU (1) SU1126209A3 (zh)
YU (1) YU117076A (zh)
ZA (1) ZA762785B (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2720968C2 (de) * 1977-05-10 1986-05-07 Kali-Chemie Pharma Gmbh, 3000 Hannover N↓1↓-Acyl-2-hydroxy-1,3-diaminopropane und Arzneimittel
DE2835708A1 (de) 1978-08-16 1980-03-06 Kali Chemie Pharma Gmbh Neue eckige klammer auf 1,2 eckige klammer zu-anellierte 7-phenyl-1,4-benzodiazepinderivate, verfahren zu deren herstellung und arzneimittel
DE3138769A1 (de) * 1981-09-30 1983-04-14 Kali-Chemie Pharma Gmbh, 3000 Hannover 7-brom-5-(2-halogenphenyl)-1h-2,3-dihydro-1,4- benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JP4940065B2 (ja) * 2007-08-29 2012-05-30 トヨタ紡織株式会社 グリースの塗布方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2265370C2 (de) * 1972-05-03 1982-12-02 Kali-Chemie Ag, 3000 Hannover 6-Phenyl-1,2,3,4-tetrahydro-1,5-benzodiazocinderivate

Also Published As

Publication number Publication date
BE841549A (fr) 1976-09-01
NO761581L (zh) 1976-11-11
SU1126209A3 (ru) 1984-11-23
JPS6212222B2 (zh) 1987-03-17
FI761284A (zh) 1976-11-11
JPS51149293A (en) 1976-12-22
DD124600A5 (zh) 1977-03-02
FI813680L (fi) 1981-11-19
PH14964A (en) 1982-02-05
FR2310765B1 (zh) 1979-07-13
SE422938B (sv) 1982-04-05
DE2520937A1 (de) 1976-11-18
DK145930B (da) 1983-04-18
DE2520937C3 (de) 1978-10-12
DE2520937B2 (de) 1978-02-16
FI62072B (fi) 1982-07-30
CA1063107A (en) 1979-09-25
PT65083A (en) 1976-06-01
CH626076A5 (en) 1981-10-30
ATA335776A (de) 1979-04-15
AU1377976A (en) 1977-11-17
MX3903E (es) 1981-09-11
HU174020B (hu) 1979-10-28
NZ180812A (en) 1978-03-06
DK145930C (da) 1983-09-26
AT353274B (de) 1979-11-12
AU498994B2 (en) 1979-03-29
FR2310765A1 (fr) 1976-12-10
PT65083B (en) 1977-09-14
NO146238C (no) 1982-08-25
ES447737A1 (es) 1977-06-01
NO146238B (no) 1982-05-18
JPS61178970A (ja) 1986-08-11
NL187631C (nl) 1991-12-02
IL49548A (en) 1980-02-29
SE7605200L (sv) 1976-11-11
CS193075B2 (en) 1979-09-17
AR209361A1 (es) 1977-04-15
FI62072C (fi) 1982-11-10
DK205676A (da) 1976-11-11
ZA762785B (en) 1977-04-27
NL7604974A (nl) 1976-11-12
YU117076A (en) 1982-08-31
IL49548A0 (en) 1976-07-30
GR60311B (en) 1978-05-08

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Legal Events

Date Code Title Description
416 Proceeding under section 16 patents act 1949
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years

Effective date: 19960509