JPS55102561A - 2-aroylformyl-substituted pyrrole derivative and its preparation - Google Patents

2-aroylformyl-substituted pyrrole derivative and its preparation

Info

Publication number
JPS55102561A
JPS55102561A JP922779A JP922779A JPS55102561A JP S55102561 A JPS55102561 A JP S55102561A JP 922779 A JP922779 A JP 922779A JP 922779 A JP922779 A JP 922779A JP S55102561 A JPS55102561 A JP S55102561A
Authority
JP
Japan
Prior art keywords
aroylformyl
preparation
formula
substituted pyrrole
pyrrole derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP922779A
Other languages
Japanese (ja)
Other versions
JPS5846513B2 (en
Inventor
Sei Kondo
Akira Negishi
Daiei Tsunemoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Priority to JP54009227A priority Critical patent/JPS5846513B2/en
Priority to IT47713/80A priority patent/IT1143954B/en
Priority to CH70980A priority patent/CH641778A5/en
Priority to SE8000734A priority patent/SE448875B/en
Publication of JPS55102561A publication Critical patent/JPS55102561A/en
Publication of JPS5846513B2 publication Critical patent/JPS5846513B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms

Abstract

NEW MATERIAL:2-Aroylformyl substituted pyrrole derivatives of formula I (R is H, alkyl, aryl; X is alkyl, alkyloxy, halogen).
EXAMPLE: 5-p-Methylbenzoyl-2-formyl-1-methylpyrrole.
USE: Synthetic precursor of 1-methyl-5-aroylpyrrole-2-acetic acid, an anti-inflammatory agent.
PREPARATION: The reaction between a 2-aroylpyrrole derivative of formula I, e.g., 2-benzoylpyrrole, and an adduct of dimethylformamide with phosphorus oxychloride is conducted at -10W40°C to give the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP54009227A 1979-01-31 1979-01-31 2↓-Aroylformyl-substituted pyrrole derivative and method for producing the same Expired JPS5846513B2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP54009227A JPS5846513B2 (en) 1979-01-31 1979-01-31 2↓-Aroylformyl-substituted pyrrole derivative and method for producing the same
IT47713/80A IT1143954B (en) 1979-01-31 1980-01-25 PYROLIC DERIVATIVES 2-AROILFORMIL SUBSTITUTED AND PROCEDURES FOR THEIR PREPARATION
CH70980A CH641778A5 (en) 1979-01-31 1980-01-29 2-Aroylformyl-substituted pyrroles and process for their preparation
SE8000734A SE448875B (en) 1979-01-31 1980-01-30 2-AROYL (FORMYL) -SUBSTITUTED PYROL RELEASES AND PROCEDURES FOR PREPARING THEREOF

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54009227A JPS5846513B2 (en) 1979-01-31 1979-01-31 2↓-Aroylformyl-substituted pyrrole derivative and method for producing the same

Publications (2)

Publication Number Publication Date
JPS55102561A true JPS55102561A (en) 1980-08-05
JPS5846513B2 JPS5846513B2 (en) 1983-10-17

Family

ID=11714519

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54009227A Expired JPS5846513B2 (en) 1979-01-31 1979-01-31 2↓-Aroylformyl-substituted pyrrole derivative and method for producing the same

Country Status (4)

Country Link
JP (1) JPS5846513B2 (en)
CH (1) CH641778A5 (en)
IT (1) IT1143954B (en)
SE (1) SE448875B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332736A (en) * 1993-11-01 1994-07-26 Ortho Pharmaceutical Corporation Anti-convulsant aroyl aminoacylpyrroles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332736A (en) * 1993-11-01 1994-07-26 Ortho Pharmaceutical Corporation Anti-convulsant aroyl aminoacylpyrroles

Also Published As

Publication number Publication date
IT1143954B (en) 1986-10-29
IT8047713A0 (en) 1980-01-25
CH641778A5 (en) 1984-03-15
JPS5846513B2 (en) 1983-10-17
SE448875B (en) 1987-03-23
SE8000734L (en) 1980-08-01

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