GB1038730A - Piperazine derivatives and processes for the production thereof - Google Patents
Piperazine derivatives and processes for the production thereofInfo
- Publication number
- GB1038730A GB1038730A GB2513164A GB2513164A GB1038730A GB 1038730 A GB1038730 A GB 1038730A GB 2513164 A GB2513164 A GB 2513164A GB 2513164 A GB2513164 A GB 2513164A GB 1038730 A GB1038730 A GB 1038730A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- alkyl
- formula
- prepared
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D311/88—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
- C07D335/14—Thioxanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D335/18—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
- C07D335/20—Thioxanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel compounds of the Formula I wherein n represents 0, 1 or 2, R represents a hydrogen atom or an alkyl radical, X represents an oxygen or a sulphur atom, Y represents a hydrogen or chlorine atom or a methyl radical, R1 represents a hydrogen atom or an alkyl, phenyl, tolyl, halophenyl, methoxyphenyl, dimethoxyphenyl, methylenedioxyphenyl, hydroxyphenyl, dimethylaminophenyl, diethylaminoethoxyphenyl, acetamidophenyl, cyanophenyl, styryl, phenylalkyl, naphthyl, pyridyl, methylpyridyl, quinolyl or ferrocenyl (see Example 4) radical, R11 represents a hydrogen atom or an alkyl or phenyl radical or wherein R1 and R11 may together represent a cycloalkylidene radical containing 5 to 12 carbon atoms inclusive or a fluoren - 9 - ylidene, indanylidene, benzocylohexylidene, phenylcyclohexylidene, or 1-alkyl - 4 - piperidylidene radical and wherein the term "alkyl" means alkyl radicals containing from 1 to 6 carbon atoms inclusive, are prepare by contacting an amine of the Formula II with a compound of the Formula R1R11C = Z wherein > C = Z represents a carbonyl radical or a radical equivalent thereto for reaction with hydrazine to form a hydrazone thereof, and where n represents 1 or 2, if desired converting into an acid addition salt. <FORM:1038730/C2/1> <FORM:1038730/C2/2> Amines of the Formula II may be prepared by reducing the corresponding 4-nitrosopiperazino-compounds, which may be prepared by reacting a xanthen-9-ol or a thioxanthen-9-ol with 1-nitrosopiperazine in an inert solvent. Amines of the Formula II where n represents 1 or 2 may be prepared by reacting 1-nitrosopiperazine with the appropriate xanthen-9-yl or thioxanthen-9-yl substituted acid chloride and reducing the resulting 4-nitrosopiperazinocarbonyl derivative.
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US333686A US3157658A (en) | 1963-07-05 | 1963-12-26 | 1-carbalkoxy-4-(9-xanthenyl) piperazines and related compounds |
US361538A US3252984A (en) | 1963-07-05 | 1964-04-21 | Esters of xanthenylpiperidinecarboxylic acid and related compounds |
US368366A US3256505A (en) | 1963-07-05 | 1964-05-18 | 1-xanthenyl-4-phenylpiperidine-4-carboxylic acid esters |
BE650047D BE650047A (en) | 1963-07-05 | 1964-07-02 | |
BR160589/64A BR6460589D0 (en) | 1963-07-05 | 1964-07-02 | PROCESS FOR THE PREPARATION OF 1-AMINO-4- HYDRAZONES (XANTHENYL AND THIOXANTHENIL) PIPERAZINES |
FR980397A FR4063M (en) | 1963-07-05 | 1964-07-02 | |
BR160588/64A BR6460588D0 (en) | 1963-07-05 | 1964-07-02 | -1-AMINO 4 HYDRAZONE PREPARATION PROCESS (XANTHENYL AND THIOXANTHENIL) PIPERAZINES |
DES91838A DE1237574B (en) | 1963-07-05 | 1964-07-02 | Process for the preparation of piperazine derivatives |
FR1599666D FR1599666A (en) | 1963-07-05 | 1964-07-02 | |
NL6407581A NL6407581A (en) | 1963-07-05 | 1964-07-03 | |
US405616A US3262934A (en) | 1963-07-05 | 1964-10-21 | Amino-substituted xanthenes and thioxanthenes |
GB48139/64A GB1029920A (en) | 1963-07-05 | 1964-11-26 | Piperazine and piperidine compounds |
BE657534D BE657534A (en) | 1963-07-05 | 1964-12-23 | |
FR999704A FR4292M (en) | 1963-07-05 | 1964-12-23 | |
FR14067A FR4382M (en) | 1963-07-05 | 1965-04-21 | |
US463929A US3374231A (en) | 1963-07-05 | 1965-06-14 | Hydrazones of 1-amino-4-(xanthenyl and thioxanthenyl)piperazines |
US525353A US3318901A (en) | 1963-07-05 | 1966-02-07 | N-dialkylaminoalkyl-1-xanthenylpiper-idinecarboxamides and related compounds |
US567041A US3356681A (en) | 1963-07-05 | 1966-07-22 | Xanthenylpiperazine anti-depressants |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29313763A | 1963-07-05 | 1963-07-05 | |
US333686A US3157658A (en) | 1963-07-05 | 1963-12-26 | 1-carbalkoxy-4-(9-xanthenyl) piperazines and related compounds |
US361538A US3252984A (en) | 1963-07-05 | 1964-04-21 | Esters of xanthenylpiperidinecarboxylic acid and related compounds |
US368366A US3256505A (en) | 1963-07-05 | 1964-05-18 | 1-xanthenyl-4-phenylpiperidine-4-carboxylic acid esters |
US405616A US3262934A (en) | 1963-07-05 | 1964-10-21 | Amino-substituted xanthenes and thioxanthenes |
US525353A US3318901A (en) | 1963-07-05 | 1966-02-07 | N-dialkylaminoalkyl-1-xanthenylpiper-idinecarboxamides and related compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1038730A true GB1038730A (en) | 1966-08-10 |
Family
ID=27559616
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2513164A Expired GB1038730A (en) | 1963-07-05 | 1964-06-17 | Piperazine derivatives and processes for the production thereof |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1038730A (en) |
-
1964
- 1964-06-17 GB GB2513164A patent/GB1038730A/en not_active Expired
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES394421A1 (en) | Phenyl-imidazolylalkanyl derivatives | |
GB1329042A (en) | Oxazolyl-acetic acid derivatives | |
GB1032889A (en) | Picolinic acid derivatives and process for their preparation | |
GB1446980A (en) | A-aminooxy-carboxylic acid hydrazides | |
GB1038730A (en) | Piperazine derivatives and processes for the production thereof | |
GB984704A (en) | Hydrazone derivatives | |
GB1006340A (en) | Hydrazone derivatives of heterocyclic compounds | |
ES342646A1 (en) | Process for the production of New N-Substituted Amides and Esteramides of Phosphoric and Thiophosphoric Acid | |
GB977071A (en) | Hydroxylamine derivatives and process for making them | |
ES413960A1 (en) | Manufacture of novel propylene-diamine derivative | |
ES297620A1 (en) | Procedure for obtaining derivatives of phenoxyactic acid (Machine-translation by Google Translate, not legally binding) | |
GB881340A (en) | Novel hydrazine derivatives and a process for the manufacture thereof | |
ES294533A1 (en) | Dibenzazepine derivatives | |
ES433843A1 (en) | Substituted 4,4-dicyclohexylmethane derivatives and microbicidal preparations containing them | |
GB764232A (en) | Quaternary ammonium salts of pyridindole derivatives | |
GB907487A (en) | Tertiary alcohols and acyl derivatives thereof | |
ES306668A1 (en) | Procedure for the preparation of 4-amino-antipirinic derivatives. (Machine-translation by Google Translate, not legally binding) | |
GB1326596A (en) | Production of selenium compounds | |
ES435935A1 (en) | A procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding) | |
GB1005723A (en) | Mixed azines | |
ES332176A1 (en) | Procedure for the preparation of antibacterial agents (Machine-translation by Google Translate, not legally binding) | |
GB1126035A (en) | New hydrazonium salts, a process for their manufacture, and preparations containing them | |
ES373302A1 (en) | Quinoxaline-di-n-oxide-lactones and their production | |
ES414894A1 (en) | 3-formylrifamycin azines | |
GB1110725A (en) | Process for preparing cyloheptimidazolinium halides |