ES435935A1 - A procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES435935A1 ES435935A1 ES435935A ES435935A ES435935A1 ES 435935 A1 ES435935 A1 ES 435935A1 ES 435935 A ES435935 A ES 435935A ES 435935 A ES435935 A ES 435935A ES 435935 A1 ES435935 A1 ES 435935A1
- Authority
- ES
- Spain
- Prior art keywords
- translation
- preparation
- machine
- legally binding
- *** translate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
A process for the preparation of benzodiazepine derivatives, of the formula ** (see formula) ** In which R means hydrogen or alkyl, R1 means hydrogen, halogen or trifluoromethyl and R2 signifies phenyl, halophenyl or pyridyl, And its 4-oxides, characterized by reacting a benzophenone of the general formula ** (see formula) ** In which R, r1 and r2 have the meaning indicated above, with a nitroacetic acid halide, to reduce the nitroacetyl compound obtained from the general formula ** (see formula) ** In which R, r1 and r2 have the meaning indicated above, the corresponding derivative of hydroxylamine or amine and cyclize the product thus obtained. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH414974A CH596173A5 (en) | 1974-03-25 | 1974-03-25 | CNS Depressant 5-aryl-benzodiazepine prepn. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES435935A1 true ES435935A1 (en) | 1976-12-16 |
Family
ID=4270728
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES435935A Expired ES435935A1 (en) | 1974-03-25 | 1975-03-24 | A procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding) |
Country Status (12)
Country | Link |
---|---|
JP (1) | JPS50130777A (en) |
AT (1) | AT351545B (en) |
CA (1) | CA1055491A (en) |
CH (1) | CH596173A5 (en) |
DD (1) | DD118644A5 (en) |
DK (1) | DK123675A (en) |
ES (1) | ES435935A1 (en) |
FI (1) | FI750380A (en) |
NL (1) | NL7502283A (en) |
NO (1) | NO751008L (en) |
SE (1) | SE7503301L (en) |
YU (1) | YU57775A (en) |
-
1974
- 1974-03-25 CH CH414974A patent/CH596173A5/en not_active IP Right Cessation
-
1975
- 1975-02-12 FI FI750380A patent/FI750380A/fi not_active Application Discontinuation
- 1975-02-26 NL NL7502283A patent/NL7502283A/en not_active Application Discontinuation
- 1975-03-10 YU YU00577/75A patent/YU57775A/en unknown
- 1975-03-20 JP JP50033118A patent/JPS50130777A/ja active Pending
- 1975-03-21 SE SE7503301A patent/SE7503301L/xx unknown
- 1975-03-24 DD DD184989A patent/DD118644A5/xx unknown
- 1975-03-24 DK DK123675A patent/DK123675A/da not_active Application Discontinuation
- 1975-03-24 AT AT224775A patent/AT351545B/en not_active IP Right Cessation
- 1975-03-24 CA CA222,888A patent/CA1055491A/en not_active Expired
- 1975-03-24 NO NO751008A patent/NO751008L/no unknown
- 1975-03-24 ES ES435935A patent/ES435935A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ATA224775A (en) | 1979-01-15 |
DK123675A (en) | 1975-09-26 |
NO751008L (en) | 1975-09-26 |
CH596173A5 (en) | 1978-02-28 |
SE7503301L (en) | 1975-09-26 |
CA1055491A (en) | 1979-05-29 |
AT351545B (en) | 1979-07-25 |
YU57775A (en) | 1982-05-31 |
FI750380A (en) | 1975-09-26 |
DD118644A5 (en) | 1976-03-12 |
NL7502283A (en) | 1975-09-29 |
JPS50130777A (en) | 1975-10-16 |
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