FR2430453A1 - Produit proteasique a pouvoir allergisant reduit - Google Patents

Produit proteasique a pouvoir allergisant reduit

Info

Publication number
FR2430453A1
FR2430453A1 FR7917249A FR7917249A FR2430453A1 FR 2430453 A1 FR2430453 A1 FR 2430453A1 FR 7917249 A FR7917249 A FR 7917249A FR 7917249 A FR7917249 A FR 7917249A FR 2430453 A1 FR2430453 A1 FR 2430453A1
Authority
FR
France
Prior art keywords
product
protease
power
proteastic
allergizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7917249A
Other languages
English (en)
Other versions
FR2430453B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri AS filed Critical Novo Industri AS
Publication of FR2430453A1 publication Critical patent/FR2430453A1/fr
Application granted granted Critical
Publication of FR2430453B1 publication Critical patent/FR2430453B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/836—Bacillus licheniformis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un produit protéasique à pouvoir allergisant réduit. Pour préparer un nouveau produit protéasique on cultive des souches de Bacillus licheniformis dont on a provoqué la mutation pour bloquer leur capacité de synthèse des protéases autres que la subtilopeptidase A (subtilisine) Øpic Bõ. L'invention s'applique en particulier à un nouveau produit protéasique destiné à être mélangé aux compositions de lavage et présentant une stabilité accrue et un pouvoir allergisant fortement réduit par rapport aux produits protéasiques du commerce dérivant de Bacillus licheniformis qui sont des mélanges de subtilisine et d'une protéase à site actif de type non-sérine.
FR7917249A 1978-07-04 1979-07-03 Produit proteasique a pouvoir allergisant reduit Expired FR2430453B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7828773 1978-07-04

Publications (2)

Publication Number Publication Date
FR2430453A1 true FR2430453A1 (fr) 1980-02-01
FR2430453B1 FR2430453B1 (fr) 1986-04-18

Family

ID=10498253

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7917249A Expired FR2430453B1 (fr) 1978-07-04 1979-07-03 Produit proteasique a pouvoir allergisant reduit

Country Status (16)

Country Link
US (1) US4266031A (fr)
EP (1) EP0006638B1 (fr)
JP (1) JPS5913187B2 (fr)
BE (1) BE877435A (fr)
BR (1) BR7904209A (fr)
CA (1) CA1142105A (fr)
CH (1) CH642395A5 (fr)
DE (2) DE2926808A1 (fr)
DK (1) DK151269C (fr)
ES (1) ES482133A1 (fr)
FR (1) FR2430453B1 (fr)
HU (1) HU182981B (fr)
IT (1) IT1162338B (fr)
NL (1) NL7905172A (fr)
SE (1) SE447661C (fr)
YU (1) YU161379A (fr)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264366A (en) * 1984-05-29 1993-11-23 Genencor, Inc. Protease deficient bacillus
JPS61250636A (ja) 1985-04-30 1986-11-07 Fuji Photo Film Co Ltd 熱現像感光材料
JPH083621B2 (ja) 1985-07-31 1996-01-17 富士写真フイルム株式会社 画像形成方法
DE3527913A1 (de) * 1985-08-03 1987-02-12 Henkel Kgaa Alkalische protease, verfahren zur herstellung von hybridvektoren und genetisch transformierte mikroorganismen
EG18543A (en) * 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
US4906575A (en) * 1987-03-06 1990-03-06 Chevron Research Company Phosphate compound that is used in a microbial profile modification process
US4947932A (en) * 1987-03-06 1990-08-14 Chevron Research Company Phosphate compound that is used in a microbial profile modification process
US5171682A (en) * 1988-03-31 1992-12-15 North Carolina State University Purified Bacillus licheniformis PWD-1 keratinase
CA2003078A1 (fr) * 1988-11-18 1990-05-18 Alan Sloma Deletion de la protease
DK63590D0 (da) * 1990-03-09 1990-03-09 Novo Nordisk As Detergentkomposition
US5863573A (en) * 1990-03-09 1999-01-26 Novo Nordisk A/S Process for producing cheese
DK63490D0 (da) * 1990-03-09 1990-03-09 Novo Nordisk As Fremgangsmaade til fremstilling af ost
ATE126970T1 (de) * 1990-03-09 1995-09-15 Novo Nordisk As Proteinhydrolysate.
DK19991D0 (da) * 1991-02-06 1991-02-06 Novo Nordisk As Proteinpraeparationer
JP3046344B2 (ja) * 1990-10-24 2000-05-29 塩野義製薬株式会社 新規プロテアーゼ
US6451586B1 (en) * 1990-11-10 2002-09-17 Roehm Gmbh & Co Kg Enzyme preparation containing protease
US5266473A (en) * 1992-01-28 1993-11-30 Kellogg Company Method for decreasing the allergenicity of psyllium seed husk by enzyme treatment
DE4329463A1 (de) * 1993-09-01 1995-03-02 Cognis Bio Umwelt Mehrenzymgranulate
SK68996A3 (en) * 1993-12-03 1997-06-04 Buckman Labor Inc Enzyme stabilization by block-copolymers
DE4344215A1 (de) * 1993-12-23 1995-06-29 Cognis Bio Umwelt Silberkorrosionsschutzmittelhaltige Enzymzubereitung
DE4422433A1 (de) * 1994-06-28 1996-01-04 Cognis Bio Umwelt Mehrenzymgranulat
DE19515072A1 (de) * 1995-04-28 1996-10-31 Cognis Bio Umwelt Cellulasehaltiges Waschmittel
DE19615776A1 (de) 1996-04-20 1997-10-23 Henkel Kgaa Löslichkeitsverbessertes Enzymgranulat
DE19651446A1 (de) 1996-12-11 1998-06-18 Henkel Kgaa Umhüllte Enzymzubereitung mit verbesserter Löslichkeit
DE19725508A1 (de) 1997-06-17 1998-12-24 Clariant Gmbh Wasch- und Reinigungsmittel
US6495136B1 (en) 1998-03-26 2002-12-17 The Procter & Gamble Company Proteases having modified amino acid sequences conjugated to addition moieties
US6908757B1 (en) 1998-03-26 2005-06-21 The Procter & Gamble Company Serine protease variants having amino acid deletions and substitutions
JP2002507426A (ja) 1998-03-26 2002-03-12 ザ、プロクター、エンド、ギャンブル、カンパニー アミノ酸置換を有するセリンプロテアーゼ変異体
US6835550B1 (en) 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
US6838269B1 (en) 1998-04-15 2005-01-04 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
US20020182184A1 (en) * 1999-07-09 2002-12-05 Pentagonal Holdings, Inc. Composition for the safe removal of indoor allergens
BR0012694A (pt) 1999-07-22 2002-04-09 Procter & Gamble Conjugado de protease, composição de limpeza e composição de tratamento pessoal
US6946128B1 (en) 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
BR0012693A (pt) 1999-07-22 2002-04-09 Procter & Gamble Variante, de protease tipo subtilisina; composição de limpeza; e composição de cuidado pessoal
CA2376045A1 (fr) 1999-07-22 2001-02-01 The Procter & Gamble Company Proteases variantes de la subtilisine par substitutions acide amine dans des regions definies de l'epitope
US6558939B1 (en) 1999-08-31 2003-05-06 Novozymes, A/S Proteases and variants thereof
US7217554B2 (en) * 1999-08-31 2007-05-15 Novozymes A/S Proteases and variants thereof
NZ531394A (en) * 1999-08-31 2005-10-28 Novozymes As Residual protease II (RPII) and variants thereof useful in detergent compositions
US7297354B2 (en) * 2000-04-26 2007-11-20 Land O'lakes, Inc. Protein material
JP2003531608A (ja) * 2000-05-04 2003-10-28 デーエスエム・ナムローゼ・フェンノートシャップ 酵素顆粒の製造方法
RU2003105683A (ru) 2000-07-28 2004-08-20 Хенкель Кгаа (De) Новый амилолитический фермент из bacillus sp.а7-7(dsm12368), а также моющее и чистящее средство с этим новым амилолитическим ферментом
DE50113038D1 (de) 2000-11-28 2007-10-31 Henkel Kgaa Cyclodextrin -glucanotransferase(cg tase) aus bacillus agaradherens(dsm 9948)sowie wasch-und reinigungsmittel mit dieser neuen cyclodextrin-glucanotransferase
DE10142124A1 (de) 2001-08-30 2003-03-27 Henkel Kgaa Umhüllte Wirkstoffzubereitung für den Einsatz in teilchenförmigen Wasch- und Reinigungsmitteln
CN1575308B (zh) 2001-10-22 2010-04-28 汉高两合股份公司 对棉有活性、具有去污能力的以氨基甲酸酯为基础的聚合物
DE10153792A1 (de) 2001-10-31 2003-05-22 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
DE10162727A1 (de) 2001-12-20 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii (DSM 14391) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE10162728A1 (de) 2001-12-20 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii (DSM 14393) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE10163748A1 (de) 2001-12-21 2003-07-17 Henkel Kgaa Neue Glykosylhydrolasen
DE10163884A1 (de) 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14392) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
US20040007251A1 (en) * 2002-07-10 2004-01-15 Kimberly-Clark Worldwide, Inc. Cleaners for the control and removal of allergens
CN102250861A (zh) 2004-02-13 2011-11-23 诺维信公司 蛋白酶变体
DE102005026522B4 (de) 2005-06-08 2007-04-05 Henkel Kgaa Verstärkung der Reinigungsleistung von Waschmitteln durch Polymer
DE102005026544A1 (de) 2005-06-08 2006-12-14 Henkel Kgaa Verstärkung der Reinigungsleistung von Waschmitteln durch Polymer
US8074973B2 (en) * 2007-10-02 2011-12-13 Exxonmobil Chemical Patents Inc. Method and apparatus for cooling pyrolysis effluent
CA2747603A1 (fr) 2008-12-31 2010-07-08 Novozymes A/S Compositions d'hydrolysat de proteine
EP2384125B1 (fr) 2008-12-31 2013-07-17 Solae, Llc Compositions d'hydrolysat de proteine presentant une aptitude a la liberation de cholecystokinine amelioree
IN2013CN00460A (fr) 2010-06-22 2015-07-03 Novozymes As
US20130331315A1 (en) 2011-02-23 2013-12-12 Solae, Llc Protein Hydrolysate Compositions Having Enhanced CCK and GLP-1 Releasing Activity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1952012C3 (de) * 1968-10-25 1974-01-24 Kyowa Hakko Kogyo Co. Ltd., Tokio Biotechnisches Verfahren zur Herstellung alkalischer Protease
GB1303633A (fr) * 1969-04-18 1973-01-17
BE755886A (fr) 1969-09-08 1971-03-08 Unilever Nv Enzyme
GB1263765A (en) 1969-11-18 1972-02-16 Godo Shusei Kabushika Kaisha A method for the production of protease by cultivating bacteria
US3623956A (en) 1970-01-21 1971-11-30 Rapidase Sa Soc Preparation of microbial alkaline protease by fermentation with bacillus subtilis, variety licheniformis
DE2063988A1 (de) 1970-12-28 1972-07-20 Henkel & Cie GmbH, 4000 Düsseldorf Verfahren zur Herstellung von Protease
FR2147470A5 (fr) * 1971-07-28 1973-03-09 Anvar

Also Published As

Publication number Publication date
FR2430453B1 (fr) 1986-04-18
SE447661C (sv) 1997-04-14
EP0006638A3 (en) 1980-02-06
CH642395A5 (de) 1984-04-13
SE447661B (sv) 1986-12-01
US4266031A (en) 1981-05-05
DK151269C (da) 1988-05-02
EP0006638B1 (fr) 1984-04-18
IT7949628A0 (it) 1979-07-03
DE2926808A1 (de) 1980-01-17
SE7905828L (sv) 1980-01-05
NL7905172A (nl) 1980-01-08
ES482133A1 (es) 1980-04-01
JPS5539794A (en) 1980-03-19
JPS5913187B2 (ja) 1984-03-28
EP0006638A2 (fr) 1980-01-09
DK151269B (da) 1987-11-16
CA1142105A (fr) 1983-03-01
DK281579A (da) 1980-01-05
DE2966911D1 (en) 1984-05-24
HU182981B (en) 1984-03-28
BE877435A (fr) 1980-01-03
IT1162338B (it) 1987-03-25
BR7904209A (pt) 1980-06-17
YU161379A (en) 1984-04-30

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Legal Events

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ST Notification of lapse