FR2421906A2 - Nouvelles oximes derivees de l'acide 3-acetoxy methyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments - Google Patents
Nouvelles oximes derivees de l'acide 3-acetoxy methyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicamentsInfo
- Publication number
- FR2421906A2 FR2421906A2 FR7736512A FR7736512A FR2421906A2 FR 2421906 A2 FR2421906 A2 FR 2421906A2 FR 7736512 A FR7736512 A FR 7736512A FR 7736512 A FR7736512 A FR 7736512A FR 2421906 A2 FR2421906 A2 FR 2421906A2
- Authority
- FR
- France
- Prior art keywords
- amino
- imino
- oxy
- acetyl
- acetoxymethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Les produits répondant à la formule du brevet principal dont les noms suivent : le 3-acétoxyméthyl 7-//2-(2-tritylamino thiazol 4-yl) 2-//(cyanométhyl)oxy/imino/acétyl/amino/ceph3-ème 4-carboxylate de tert-butyle isomère syn, l'acide 3-acétoxyméthyl 7-//2-(2-amino thiazol 4-yl)2-//(cyanométhyl)oxy/imino/acétyl/amino/ceph-3-ème 4-carboxylique isomere syn et son sel de sodium, le 3-acétoxyméthyl 7-//2-(2-triylaminothiazol 4-yl) 2-///(aminocarbonyl)méthyl/oxy/imino/acétyl/amino/ceph-3-ème 4-carboxylate de tert-butyle isomère syn, l'acide 3-acétoxyméthyl 7-//2-(2-amino thiazol 4-yl) 2-///(aminocarbonyl)méthyl/oxy/imino/acétyl/amino/ceph-3-ème 4-carboxylique isomère syn et son sel de sodium, le 3-acétoxyméthyl 7-//2-(2-tritylamino thiazol 4-yl) 2-//(1-tertbutoxycarbonyl 1-méthyl éthyl)oxy/imino/acétyl/amino/ceph-3-ème 4-carboylate de tert-butyle isomère syn, l'acide 3-acétoxyméthyl 7-//2-(2-amino 4-thiazolyl) 2-//(1-carboxy 1-méthyl éthyl)oxy/imino/acétyl/amino/ceph-3-ème 4-carboxylique isomère syn et son sel disodique. Variante du procédé décrit au brevet principal et application à titre de médicaments des produits.
Priority Applications (36)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7736512A FR2421906A2 (fr) | 1977-12-05 | 1977-12-05 | Nouvelles oximes derivees de l'acide 3-acetoxy methyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
SE7802833A SE439312B (sv) | 1977-03-25 | 1978-03-13 | Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra |
SU782588855A SU882412A3 (ru) | 1977-12-05 | 1978-03-14 | Способ получени производных 7-[2-(2-аминотиазол-4-ил)-2-метоксииминоацетамидо]-3-ацетоксиметил-3-цефем-4-карбоновой кислоты в виде син-изомеров |
US05/886,421 US4288434A (en) | 1977-03-25 | 1978-03-14 | Cephalosporanic acid derivatives |
DE2858771A DE2858771C2 (fr) | 1977-03-25 | 1978-03-22 | |
DK129578A DK159156C (da) | 1977-03-25 | 1978-03-22 | Analogifremgangsmaade til fremstilling af (2-(2-aminothiazol-4-yl)-2-(0-substitueret)-oxyiminoacetamido)-7-cephalosporan-syre og fysiologisk acceptable salte deraf |
ES468169A ES468169A1 (es) | 1977-03-25 | 1978-03-22 | Procedimiento de preparacion de nuevas oximas derivadas del acido 3-acetoximetil-7-aminotiazolil-acetamido-cefalospora- nico. |
HU78RO972A HU182567B (en) | 1977-03-25 | 1978-03-22 | Prcess for preparing new oxime derivatives of 3-acetoxymethyl-7-amino-thiazolyl-acetamido-cef-3-em-4-carboxylic acid |
DE19782812625 DE2812625A1 (de) | 1977-03-25 | 1978-03-22 | Oximderivate der 3-acetoxymethyl-7- aminothiazolyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische mittel |
GB16825/80A GB1605176A (en) | 1977-03-25 | 1978-03-23 | Oxime derivatives of 7-amino-thiazolyl-acetic acid and processes for preparing them |
AU34471/78A AU520657B2 (en) | 1977-03-25 | 1978-03-23 | Oxime Derivatives of 3- acetoxy methyl 7-amino thiazolyl acetamido cephalosporanic acid, process for preparing them and pharmaceutical compositions |
CA299,661A CA1125280A (fr) | 1977-03-25 | 1978-03-23 | Procede de preparation de nouvelles oximes derivees de l'acide 3-acetoxymethyl 7-amino thiazolyl acetamido cephalosporanique |
PT67815A PT67815A (fr) | 1977-03-25 | 1978-03-23 | Procede de preparation de nouvelles oximes derivees de l'acide 3-acetoxymethyl 7-aminothiazolyl acetamido cephalosporanique |
CH1361/84A CH648555A5 (fr) | 1977-03-25 | 1978-03-23 | Ester d'un acide thiazolyl acetique. |
NL7803166A NL192041C (nl) | 1977-03-25 | 1978-03-23 | Geneesmiddel met antibacteriële werking, alsmede 7-£2-(2-aminothiazool-4-yl)-2-(veretherd oxyimino)-aceetamido|-3-cefem -4-carbonzuurderivaten. |
CH322978A CH633292A5 (fr) | 1977-03-25 | 1978-03-23 | Oximes derivees de l'acide 3-acetoxymethyl 7-amino thiazolyl acetamido cephalosporanique, procede de preparation et compositions pharmaceutiques. |
GB11613/78A GB1605175A (en) | 1977-03-25 | 1978-03-23 | Oxime derivatives of 7-(amino-thiazolyl-acetamido)-cephalosporanic acid process for preparing them and pharmaceutical compositions containing them |
JP3319378A JPS53119887A (en) | 1977-03-25 | 1978-03-24 | Novel oxime derivative of 33acetoxymethyll 77aminothiazolylacetoamide cephalospolanate process for preparing same and pharmaceutical composition |
IT48604/78A IT1103478B (it) | 1977-03-25 | 1978-03-24 | Ossime derivate dall'acido 3-acetos simetil 7-ammino-tiazolil-acetammido cefalosporanico procedimento per la loro produzione e composizioni farmaceutiche che le contengono come ingrediente attivo |
LU79312A LU79312A1 (fr) | 1977-03-25 | 1978-03-24 | Procede de preparation de nouvelles oximes derivees de l'acide 3-acetoxymethyl-7-amino thiazolyl acetamido cephalosporanique |
PH20927A PH15764A (en) | 1977-03-25 | 1978-03-27 | Cephalosporanic acid derivatives |
AT218378A AT360153B (de) | 1977-03-25 | 1978-03-28 | Verfahren zur herstellung von neuen ver- bindungen |
IE1518/83A IE47362B1 (en) | 1977-03-25 | 1978-03-29 | New oxime derivatives of 7-amino-thiazolyl-acetic acid,and processes for preparing them |
IE604/78A IE47361B1 (en) | 1977-03-25 | 1978-03-29 | New oxime derivatives of (amino-thiazolyl-acetamido)-cephalosporanic acid,processes for preparing them and pharmaceutical compositions containing them |
GB307781A GB1605177A (en) | 1977-12-05 | 1978-05-31 | Oxime derivatives of 5'-amino-thiazolyl-acetic acid and processes for preparing them |
ES477592A ES477592A1 (es) | 1977-03-25 | 1979-02-09 | Procedimiento de preparacion de nuevas oximas derivadas del acido 3-acetoximetil-7-aminotiazolil-acetamido-cefalospora- nico. |
AT607579A AT361122B (de) | 1977-12-05 | 1979-09-14 | Verfahren zur herstellung neuer verbindungen |
AT331380A AT376215B (de) | 1977-03-25 | 1980-06-24 | Verfahren zur herstellung neuer substituierter 2-(2-amino-4-thiazolyl)-2-hydroxyiminoessigsaeur n |
US06/260,311 US4386210A (en) | 1977-03-25 | 1981-05-04 | 2-(2-Amino-4-thiazolyl)-2-methoxyimino-acetic acid derivatives |
CA379,842A CA1132575A (fr) | 1977-03-25 | 1981-06-16 | Derives de l'acide 2-(2-amino 4-thiazolyl) 2- hydroxyimino acetique et procede pour leur preparation preparation |
CH386882A CH639652A5 (fr) | 1977-03-25 | 1982-06-18 | Acides thiazolyl acetiques, leurs esters et leurs procedes de preparation. |
US06/469,710 US4487937A (en) | 1977-03-25 | 1983-02-25 | 2-(2-Substitutedamino-4-thiazolyl)-2-(1-methoxy-isopropoxyimino)-acetic acids |
SE8304239A SE453192B (sv) | 1977-03-25 | 1983-08-02 | Nya mellanprodukter anvendbara for framstellning av oximderivat av 3-acetoximetyl-7-aminotiazolyl-acetamido-cefalosporinsyra samt forfarande for framstellning av mellanprodukterna |
CH644383A CH646159A5 (fr) | 1977-03-25 | 1983-12-02 | Acides thiazolyl acetiques et leur preparation. |
US06/574,876 US4483981A (en) | 1977-03-25 | 1984-01-30 | Cephalosporanic acid derivatives |
JP63152471A JPS6425768A (en) | 1977-03-25 | 1988-06-22 | 2-(2-amino-4-thiazolyl)-2-methoxyiminoacetic acid derivative and manufacture |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7736512A FR2421906A2 (fr) | 1977-12-05 | 1977-12-05 | Nouvelles oximes derivees de l'acide 3-acetoxy methyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2421906A2 true FR2421906A2 (fr) | 1979-11-02 |
FR2421906B2 FR2421906B2 (fr) | 1984-05-25 |
Family
ID=9198438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7736512A Granted FR2421906A2 (fr) | 1977-03-25 | 1977-12-05 | Nouvelles oximes derivees de l'acide 3-acetoxy methyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
Country Status (3)
Country | Link |
---|---|
FR (1) | FR2421906A2 (fr) |
GB (1) | GB1605177A (fr) |
SU (1) | SU882412A3 (fr) |
-
1977
- 1977-12-05 FR FR7736512A patent/FR2421906A2/fr active Granted
-
1978
- 1978-03-14 SU SU782588855A patent/SU882412A3/ru active
- 1978-05-31 GB GB307781A patent/GB1605177A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
SU882412A3 (ru) | 1981-11-15 |
FR2421906B2 (fr) | 1984-05-25 |
GB1605177A (en) | 1982-11-17 |
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