FI970967A - Heterosyklinen johdannainen ja lääkeaine - Google Patents
Heterosyklinen johdannainen ja lääkeaine Download PDFInfo
- Publication number
- FI970967A FI970967A FI970967A FI970967A FI970967A FI 970967 A FI970967 A FI 970967A FI 970967 A FI970967 A FI 970967A FI 970967 A FI970967 A FI 970967A FI 970967 A FI970967 A FI 970967A
- Authority
- FI
- Finland
- Prior art keywords
- alkyl
- substituted
- compound
- represent
- drug
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/38—One sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
- C07D251/22—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to two ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21621494 | 1994-09-09 | ||
PCT/JP1995/001792 WO1996007641A1 (fr) | 1994-09-09 | 1995-09-08 | Derive heterocyclique et medicament |
Publications (2)
Publication Number | Publication Date |
---|---|
FI970967A true FI970967A (fi) | 1997-03-07 |
FI970967A0 FI970967A0 (fi) | 1997-03-07 |
Family
ID=16685068
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI970967A FI970967A0 (fi) | 1994-09-09 | 1997-03-07 | Heterosyklinen johdannainen ja lääkeaine |
Country Status (19)
Country | Link |
---|---|
US (2) | US5945426A (fi) |
EP (1) | EP0781766B1 (fi) |
JP (2) | JP3036079B2 (fi) |
KR (1) | KR100358245B1 (fi) |
CN (1) | CN1118454C (fi) |
AT (1) | ATE263154T1 (fi) |
BR (1) | BR9508900A (fi) |
CA (1) | CA2199518A1 (fi) |
DE (1) | DE69532811T2 (fi) |
DK (1) | DK0781766T3 (fi) |
ES (1) | ES2218552T3 (fi) |
FI (1) | FI970967A0 (fi) |
HU (1) | HU221855B1 (fi) |
MX (1) | MX9701765A (fi) |
NO (1) | NO312995B1 (fi) |
NZ (1) | NZ292269A (fi) |
PT (1) | PT781766E (fi) |
RU (1) | RU2128996C1 (fi) |
WO (1) | WO1996007641A1 (fi) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1300056B1 (it) | 1998-04-17 | 2000-04-05 | Boehringer Ingelheim Italia | Eterocicli con anello a 6 termini difenil-sostituiti loro procedimento di preparazione e loro impiego come farmaci |
WO2000010571A1 (fr) * | 1998-08-25 | 2000-03-02 | Nippon Shinyaku Co., Ltd. | Antagonistes des canaux calciques |
US20040077709A1 (en) * | 1999-05-31 | 2004-04-22 | Daiichi Pharmaceutical Co., Ltd. | Neuronal death inhibitors |
GB0003224D0 (en) | 2000-02-11 | 2000-04-05 | Glaxo Group Ltd | Chemical compounds |
GB0021494D0 (en) | 2000-09-01 | 2000-10-18 | Glaxo Group Ltd | Chemical comkpounds |
WO2002020494A1 (fr) * | 2000-09-08 | 2002-03-14 | Nippon Shinyaku Co., Ltd. | Procede de production d'un derive de pyrimidine et intermediaire approprie |
DE60107603T2 (de) * | 2000-09-19 | 2005-10-06 | Sumitomo Chemical Co. Ltd. | Pyrimidinverbindungen und deren verwendung als pestizide |
GB0112810D0 (en) | 2001-05-25 | 2001-07-18 | Glaxo Group Ltd | Pyrimidine derivatives |
GB0112802D0 (en) | 2001-05-25 | 2001-07-18 | Glaxo Group Ltd | Pyrimidine derivatives |
GB0119477D0 (en) | 2001-08-09 | 2001-10-03 | Glaxo Group Ltd | Pyrimidine derivatives |
US7235560B2 (en) | 2002-08-19 | 2007-06-26 | Glaxo Group Limited | Pyrimidine derivative as selective COX-2 inhibitors |
GB0221443D0 (en) | 2002-09-16 | 2002-10-23 | Glaxo Group Ltd | Pyridine derivates |
EP1599468B1 (en) | 2003-01-14 | 2007-10-03 | Arena Pharmaceuticals, Inc. | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
AU2003222444A1 (en) * | 2003-03-31 | 2004-10-25 | Council Of Scientific And Industrial Research | NEW PYRIMIDINE LINKED PYRROLO(2,1-c)(1,4)BENZODIAZEPINES AS POTENTIAL ANTITUMOUR AGENTS |
AR045047A1 (es) * | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
EP2287165A3 (en) | 2003-07-14 | 2011-06-22 | Arena Pharmaceuticals, Inc. | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
US6966680B2 (en) * | 2003-11-28 | 2005-11-22 | Edward Kratz | Decorative lighting display with changeable shades and bulbs |
DE602005011279D1 (de) * | 2004-06-04 | 2009-01-08 | Arena Pharm Inc | Substituierte aryl- und heteroarylderivate als modulatoren des stoffwechsels und für die prophylaxe und behandlung von damit in zusammenhang stehenden erkrankungen |
DOP2006000010A (es) | 2005-01-10 | 2006-07-31 | Arena Pharm Inc | Procedimiento para preparar eteres aromáticos |
MY148521A (en) * | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
RS20080112A (en) * | 2005-09-16 | 2009-05-06 | Arena Pharmaceuticals Inc., | Modulators of metabolism and the treatment of disorders related thereto |
TW200811140A (en) * | 2006-07-06 | 2008-03-01 | Arena Pharm Inc | Modulators of metabolism and the treatment of disorders related thereto |
TW200811147A (en) * | 2006-07-06 | 2008-03-01 | Arena Pharm Inc | Modulators of metabolism and the treatment of disorders related thereto |
EP1941879A1 (en) * | 2007-01-05 | 2008-07-09 | PAION Deutschland GmbH | Neuroprotective agent for the treatment of neuronal damage |
EP2008653A1 (de) | 2007-06-28 | 2008-12-31 | Charité-Universitätsmedizin Berlin | Serotonerge Verbindungen zur Behandlung neuronaler Krankheiten |
DE102007051090A1 (de) | 2007-06-28 | 2009-01-08 | Charité - Universitätsmedizin Berlin | SSRI zur Behandlung neuronaler Krankheiten |
SG10201906876PA (en) | 2010-01-27 | 2019-09-27 | Arena Pharm Inc | Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof |
AU2011305525B2 (en) | 2010-09-22 | 2016-08-18 | Arena Pharmaceuticals, Inc. | Modulators of the GPR119 receptor and the treatment of disorders related thereto |
CN116850181A (zh) | 2015-01-06 | 2023-10-10 | 艾尼纳制药公司 | 治疗与s1p1受体有关的病症的方法 |
ES2929526T3 (es) | 2015-06-22 | 2022-11-29 | Arena Pharm Inc | Sal cristalina de L-arginina del ácido (R)-2-(7-(4-ciclopentil-3-(trifluorometil)benciloxi)-1,2,3,4-tetrahidrociclo-penta[b]indol-3-il)acético para su uso en trastornos asociados al receptor S1P1 |
MA47504A (fr) | 2017-02-16 | 2019-12-25 | Arena Pharm Inc | Composés et méthodes de traitement de l'angiocholite biliaire primitive |
EP3953762B1 (en) * | 2019-04-09 | 2022-09-14 | Gentex Corporation | Low dimerizing viologen electrochromic compounds and devices |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3167553A (en) * | 1963-05-08 | 1965-01-26 | Searle & Co | 2-amino-4-ethereal-5-methyl-6-phenylpyrimidines |
BE756127A (fr) * | 1969-09-12 | 1971-03-15 | Hoechst Ag | Ethers heterocycliques et leur preparation |
JPS4921148B1 (fi) * | 1970-12-28 | 1974-05-30 | ||
US3937712A (en) * | 1971-09-22 | 1976-02-10 | Boehringer Ingelheim Gmbh | (5-nitro-2-furyl)-pyridines |
BE789099A (fr) * | 1971-09-22 | 1973-03-21 | Boehringer Sohn Ingelheim | Nouveaux derives de la pyridine et procede pour les fabriquer |
US4115575A (en) * | 1973-02-20 | 1978-09-19 | Ciba-Geigy Corporation | 2-(3-Amino-2-hydroxy-propoxy)-pyrazines |
US4698340A (en) * | 1984-07-19 | 1987-10-06 | Fujisawa Pharmaceutical Co., Ltd. | Pyrimidine derivatives, processes for preparation thereof and composition containing the same |
US4727073A (en) * | 1984-10-01 | 1988-02-23 | Fujisawa Pharmaceutical Co., Ltd. | Pyrimidine derivatives and composition of the same |
EP0555478A4 (en) * | 1990-08-31 | 1993-11-18 | Nippon Shinyaku Company, Limited | Pyrimidine derivative and medicine |
US5294612A (en) * | 1992-03-30 | 1994-03-15 | Sterling Winthrop Inc. | 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof |
IL117659A (en) * | 1995-04-13 | 2000-12-06 | Dainippon Pharmaceutical Co | Substituted 2-phenyl pyrimidino amino acetamide derivative process for preparing the same and a pharmaceutical composition containing same |
-
1995
- 1995-09-08 AT AT95930725T patent/ATE263154T1/de not_active IP Right Cessation
- 1995-09-08 HU HU9800853A patent/HU221855B1/hu not_active IP Right Cessation
- 1995-09-08 DK DK95930725T patent/DK0781766T3/da active
- 1995-09-08 PT PT95930725T patent/PT781766E/pt unknown
- 1995-09-08 NZ NZ292269A patent/NZ292269A/en unknown
- 1995-09-08 DE DE69532811T patent/DE69532811T2/de not_active Expired - Fee Related
- 1995-09-08 KR KR1019970701494A patent/KR100358245B1/ko not_active IP Right Cessation
- 1995-09-08 MX MX9701765A patent/MX9701765A/es not_active IP Right Cessation
- 1995-09-08 BR BR9508900A patent/BR9508900A/pt not_active IP Right Cessation
- 1995-09-08 CA CA002199518A patent/CA2199518A1/en not_active Abandoned
- 1995-09-08 RU RU97105769A patent/RU2128996C1/ru not_active IP Right Cessation
- 1995-09-08 US US08/809,004 patent/US5945426A/en not_active Expired - Fee Related
- 1995-09-08 EP EP95930725A patent/EP0781766B1/en not_active Expired - Lifetime
- 1995-09-08 ES ES95930725T patent/ES2218552T3/es not_active Expired - Lifetime
- 1995-09-08 JP JP8509379A patent/JP3036079B2/ja not_active Expired - Fee Related
- 1995-09-08 WO PCT/JP1995/001792 patent/WO1996007641A1/ja active IP Right Grant
- 1995-09-08 CN CN95195014A patent/CN1118454C/zh not_active Expired - Fee Related
-
1997
- 1997-03-07 FI FI970967A patent/FI970967A0/fi unknown
- 1997-03-07 NO NO19971050A patent/NO312995B1/no unknown
-
1999
- 1999-06-16 US US09/334,253 patent/US6191149B1/en not_active Expired - Fee Related
- 1999-11-26 JP JP33560399A patent/JP3312616B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5945426A (en) | 1999-08-31 |
US6191149B1 (en) | 2001-02-20 |
KR100358245B1 (ko) | 2003-11-28 |
MX9701765A (es) | 1997-06-28 |
JP2000136184A (ja) | 2000-05-16 |
CN1157609A (zh) | 1997-08-20 |
WO1996007641A1 (fr) | 1996-03-14 |
CN1118454C (zh) | 2003-08-20 |
NO971050L (no) | 1997-05-09 |
RU2128996C1 (ru) | 1999-04-20 |
DE69532811T2 (de) | 2005-03-17 |
AU3399695A (en) | 1996-03-27 |
AU701395B2 (en) | 1999-01-28 |
FI970967A0 (fi) | 1997-03-07 |
DE69532811D1 (de) | 2004-05-06 |
CA2199518A1 (en) | 1996-03-14 |
BR9508900A (pt) | 1997-12-30 |
JP3036079B2 (ja) | 2000-04-24 |
ATE263154T1 (de) | 2004-04-15 |
PT781766E (pt) | 2004-07-30 |
NO312995B1 (no) | 2002-07-29 |
EP0781766A1 (en) | 1997-07-02 |
DK0781766T3 (da) | 2004-07-26 |
EP0781766A4 (en) | 1998-01-14 |
EP0781766B1 (en) | 2004-03-31 |
ES2218552T3 (es) | 2004-11-16 |
NZ292269A (en) | 1998-09-24 |
HU221855B1 (hu) | 2003-02-28 |
HUT77779A (hu) | 1998-08-28 |
NO971050D0 (no) | 1997-03-07 |
KR970705545A (ko) | 1997-10-09 |
JP3312616B2 (ja) | 2002-08-12 |
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