FI970357A0 - Benzoxazole and pyridine derivatives useful in the treatment of type II diabetes - Google Patents

Benzoxazole and pyridine derivatives useful in the treatment of type II diabetes

Info

Publication number
FI970357A0
FI970357A0 FI970357A FI970357A FI970357A0 FI 970357 A0 FI970357 A0 FI 970357A0 FI 970357 A FI970357 A FI 970357A FI 970357 A FI970357 A FI 970357A FI 970357 A0 FI970357 A0 FI 970357A0
Authority
FI
Finland
Prior art keywords
benzoxazole
diabetes
treatment
type
pyridine derivatives
Prior art date
Application number
FI970357A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI970357A (en
Inventor
David Haigh
Harshad Kantilal Rami
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9415330A external-priority patent/GB9415330D0/en
Priority claimed from GBGB9425599.9A external-priority patent/GB9425599D0/en
Priority claimed from GBGB9509923.0A external-priority patent/GB9509923D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of FI970357A0 publication Critical patent/FI970357A0/en
Publication of FI970357A publication Critical patent/FI970357A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI970357A 1994-07-29 1997-01-28 Benzoxazole and pyridine derivatives useful in the treatment of type II diabetes FI970357A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9415330A GB9415330D0 (en) 1994-07-29 1994-07-29 Novel compounds
GBGB9425599.9A GB9425599D0 (en) 1994-12-19 1994-12-19 Novel compounds
GBGB9509923.0A GB9509923D0 (en) 1995-05-17 1995-05-17 Novel compounds
PCT/GB1995/001323 WO1996004261A1 (en) 1994-07-29 1995-06-07 Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes
PCT/EP1995/003038 WO1996004260A1 (en) 1994-07-29 1995-07-28 Benzoxazoles and pyridine derivatives useful in the treatment of the type ii diabetes

Publications (2)

Publication Number Publication Date
FI970357A0 true FI970357A0 (en) 1997-01-28
FI970357A FI970357A (en) 1997-03-26

Family

ID=27267309

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970357A FI970357A (en) 1994-07-29 1997-01-28 Benzoxazole and pyridine derivatives useful in the treatment of type II diabetes

Country Status (16)

Country Link
EP (1) EP0772605A1 (en)
AP (1) AP776A (en)
BR (1) BR9508468A (en)
CA (1) CA2196079A1 (en)
CZ (1) CZ25497A3 (en)
DZ (1) DZ1916A1 (en)
FI (1) FI970357A (en)
HU (1) HUT76637A (en)
IL (3) IL114759A (en)
MA (1) MA23632A1 (en)
MX (1) MX9700763A (en)
NO (1) NO307827B1 (en)
OA (1) OA10470A (en)
PL (1) PL318766A1 (en)
SK (1) SK12297A3 (en)
WO (2) WO1996004261A1 (en)

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AU752059B2 (en) 1997-10-27 2002-09-05 Dr. Reddy's Laboratories Limited Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them
WO1999019313A1 (en) * 1997-10-27 1999-04-22 Dr. Reddy's Research Foundation Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
US6369067B1 (en) 1997-10-27 2002-04-09 Dr. Reddy's Research Foundation Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
US6440961B1 (en) 1997-10-27 2002-08-27 Dr. Reddy's Research Foundation Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
US6444816B1 (en) 1997-10-27 2002-09-03 Dr. Reddy's Research Foundation Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof
WO1999016758A1 (en) 1997-10-27 1999-04-08 Dr. Reddy's Research Foundation Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
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US6265401B1 (en) * 1997-10-27 2001-07-24 Reddy-Cheminor, Inc. Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
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HUP0104240A2 (en) 1998-09-17 2002-03-28 Bristol-Myers Squibb Company Method for treating atherosclerosis employing an ap2 inhibitor and combination
US6248781B1 (en) 1998-10-21 2001-06-19 Novo Nordisk A/S Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
US6468996B1 (en) 1998-10-21 2002-10-22 Novo Nordisk A/S Substituted hetero-polycyclic compounds as PPARα and PPARγ activators
AU6325699A (en) * 1998-10-21 2000-05-08 Dr. Reddy's Research Foundation New compounds, their preparation and use
WO2000023445A1 (en) * 1998-10-21 2000-04-27 Novo Nordisk A/S New compounds, their preparation and use
JP2002527503A (en) * 1998-10-21 2002-08-27 ノボ ノルディスク アクティーゼルスカブ New compounds, their preparation and use
US6300339B1 (en) 1998-10-21 2001-10-09 Novo Nordisk A/S Compounds, their preparation and use
AU6190299A (en) * 1998-10-21 2000-05-08 Dr. Reddy's Research Foundation New compounds, their preparation and use
US6365586B1 (en) 1998-10-21 2002-04-02 Novo Nordisk A/S Compounds, their preparation and use
EP1123297A1 (en) * 1998-10-21 2001-08-16 Novo Nordisk A/S New compounds, their preparation and use
EP1123267A1 (en) 1998-10-21 2001-08-16 Novo Nordisk A/S New compounds, their preparation and use
US6214820B1 (en) 1998-10-21 2001-04-10 Novo Nordisk A/S Compounds, their preparation and use
BR9914438A (en) * 1998-10-29 2001-06-26 Reddy Research Foundation Improved process for preparing new anti-diabetic agents
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
AU3957800A (en) * 1999-04-16 2000-11-02 Dr. Reddy's Research Foundation Crystalline r- guanidines, arginine or (l) -arginine (2(s)) -2- ethoxy -3-(4- (2-(10(h) -phenoxazin -10-yl)ethoxy}phenyl)propanoate
AU3958100A (en) 1999-04-20 2000-11-02 Novo Nordisk A/S New compounds, their preparation and use
IL145789A0 (en) * 1999-04-20 2002-07-25 Novo Nordisk As Derivatives of propionic acid, their preparation and pharmaceutical compositions containing them
US7414128B2 (en) 1999-04-20 2008-08-19 Dr. Reddy's Laboratories, Limited Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate
JP2002542237A (en) * 1999-04-20 2002-12-10 ノボ ノルディスク アクティーゼルスカブ New compounds, their production and use
US6274608B1 (en) 1999-04-20 2001-08-14 Novo Nordisk A/S Compounds, their preparation and use
US6972294B1 (en) 1999-04-20 2005-12-06 Novo Nordisk, A/S Compounds, their preparation and use
US6369055B1 (en) 1999-04-20 2002-04-09 Novo Nordisk A/S Compounds, their preparation and use
WO2000066572A1 (en) * 1999-04-28 2000-11-09 Dr. Reddy's Research Foundation Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents
US6417212B1 (en) 1999-08-27 2002-07-09 Eli Lilly & Company Modulators of peroxisome proliferator activated receptors
KR100649304B1 (en) * 2000-01-19 2006-11-24 카딜라 헬스케어 리미티드 Novel compounds having hypolipedemic, hypochoresteremic activities, process for their preparation and pharmaceutical compositions containg them
US6555577B1 (en) 2000-01-28 2003-04-29 Novo Nordisk A/S Compounds, their preparation and use
CN1396904A (en) * 2000-01-28 2003-02-12 诺沃挪第克公司 Novel compound, their preparation and use
US6569901B2 (en) 2000-01-28 2003-05-27 Novo Nordisk A/S Alkynyl-substituted propionic acid derivatives, their preparation and use
US6509374B2 (en) 2000-04-17 2003-01-21 Novo Nordisk A/S Compounds, their preparation and use
AU2001263083A1 (en) * 2000-05-12 2001-11-26 Ortho-Mcneil Pharmaceutical, Inc. Biologically active 4h-benzo(1,4)oxazin-3-ones
WO2001087860A2 (en) * 2000-05-12 2001-11-22 Ortho-Mcneil Pharmaceutical, Inc. Novel benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment
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AU2002351752A1 (en) 2001-12-29 2003-07-30 Novo Nordisk A/S Combined use of a glp-1 compound and another drug for treating dyslipidemia
US7015345B2 (en) 2002-02-21 2006-03-21 Asahi Kasei Pharma Corporation Propionic acid derivatives
US7816385B2 (en) 2002-12-20 2010-10-19 High Point Pharmaceuticals, Llc Dimeric dicarboxylic acid derivatives, their preparation and use
US6653334B1 (en) 2002-12-27 2003-11-25 Kowa Co., Ltd. Benzoxazole compound and pharmaceutical composition containing the same
EP2154131A4 (en) * 2007-04-26 2011-09-21 Pharmafrontier Co Ltd G protein-coupled receptor inhibitor and pharmaceutical product
CA2825456C (en) 2011-01-31 2016-01-05 Cadila Healthcare Limited Treatment for lipodystrophy
CN105377246B (en) 2013-04-22 2018-03-20 卡迪拉保健有限公司 For non-alcohol fatty liver (NAFLD) new compositions
EP3004053B1 (en) 2013-05-30 2021-03-24 Cadila Healthcare Limited A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
TW201636015A (en) 2013-07-05 2016-10-16 卡地拉保健有限公司 Synergistic compositions
IN2013MU02470A (en) 2013-07-25 2015-06-26 Cadila Healthcare Ltd
WO2015033357A2 (en) 2013-09-06 2015-03-12 Cadila Healthcare Limited An improved process for the preparation of pyrrole derivatives
US10385017B2 (en) 2015-10-14 2019-08-20 Cadila Healthcare Limited Pyrrole compound, compositions and process for preparation thereof
BR112019011740A2 (en) 2016-12-09 2019-10-29 Cadila Healthcare Ltd Pharmaceutical composition and method for the treatment of primary biliary cholangitis

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US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
PL176885B1 (en) * 1992-07-03 1999-08-31 Smithkline Beecham Plc Pharmaceutic composition

Also Published As

Publication number Publication date
AP776A (en) 1999-10-28
IL125525A (en) 2000-02-29
MA23632A1 (en) 1996-04-01
FI970357A (en) 1997-03-26
NO970373D0 (en) 1997-01-28
MX9700763A (en) 1997-05-31
IL114759A0 (en) 1995-12-31
CA2196079A1 (en) 1996-02-15
IL114759A (en) 1999-10-28
CZ25497A3 (en) 1997-09-17
WO1996004261A1 (en) 1996-02-15
IL125525A0 (en) 1999-03-12
PL318766A1 (en) 1997-07-07
OA10470A (en) 2002-04-08
NO970373L (en) 1997-03-18
HUT76637A (en) 1997-10-28
DZ1916A1 (en) 2002-02-17
NO307827B1 (en) 2000-06-05
AP9700918A0 (en) 1997-01-31
EP0772605A1 (en) 1997-05-14
WO1996004260A1 (en) 1996-02-15
SK12297A3 (en) 1997-08-06
BR9508468A (en) 1997-11-25

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