NO970373D0 - Benzoxazoles and pyridine derivatives useful in the treatment of type II diabetes - Google Patents
Benzoxazoles and pyridine derivatives useful in the treatment of type II diabetesInfo
- Publication number
- NO970373D0 NO970373D0 NO970373A NO970373A NO970373D0 NO 970373 D0 NO970373 D0 NO 970373D0 NO 970373 A NO970373 A NO 970373A NO 970373 A NO970373 A NO 970373A NO 970373 D0 NO970373 D0 NO 970373D0
- Authority
- NO
- Norway
- Prior art keywords
- benzoxazoles
- diabetes
- treatment
- type
- pyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
| GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
| GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
| PCT/GB1995/001323 WO1996004261A1 (en) | 1994-07-29 | 1995-06-07 | Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes |
| PCT/EP1995/003038 WO1996004260A1 (en) | 1994-07-29 | 1995-07-28 | Benzoxazoles and pyridine derivatives useful in the treatment of the type ii diabetes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO970373D0 true NO970373D0 (en) | 1997-01-28 |
| NO970373L NO970373L (en) | 1997-03-18 |
| NO307827B1 NO307827B1 (en) | 2000-06-05 |
Family
ID=27267309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO970373A NO307827B1 (en) | 1994-07-29 | 1997-01-28 | Benzoxazole and pyridine derivatives, their use and pharmaceutical preparations containing them |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0772605A1 (en) |
| AP (1) | AP776A (en) |
| BR (1) | BR9508468A (en) |
| CA (1) | CA2196079A1 (en) |
| CZ (1) | CZ25497A3 (en) |
| DZ (1) | DZ1916A1 (en) |
| FI (1) | FI970357A (en) |
| HU (1) | HUT76637A (en) |
| IL (3) | IL114759A (en) |
| MA (1) | MA23632A1 (en) |
| MX (1) | MX9700763A (en) |
| NO (1) | NO307827B1 (en) |
| OA (1) | OA10470A (en) |
| PL (1) | PL318766A1 (en) |
| SK (1) | SK12297A3 (en) |
| WO (2) | WO1996004261A1 (en) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
| NZ332136A (en) * | 1996-04-04 | 1999-08-30 | Sankyo Co | Phenylalkylcarboxylic acid derivatives useful for treating hyperglycemia |
| US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
| US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
| BR9813019A (en) | 1997-10-02 | 2000-09-05 | Sankyo Co | Derivatives of amidocarboxylic acid, agents for lowering blood glucose, reducing lipid, for improving insulin resistance, anti-inflammatory, for immuno-regulation, for inhibiting aldose reductase, for inhibiting 5-lipoxygenase, for the generation of suppressor of lipid peroxide, to activate ppar, to reduce osteoporosis, and compositions for the therapy or prevention of diabetes mellitus, hyperlipemia, obesity, impaired glucose tolerance, insulin resistance other than igt, liver fatty, diabetic complications, arteriosclerosis, gestational diabetes mellitus, polycystic ovary syndrome, arthroesthesis, rheumatoid arthritis, allergic diseases, asthma, cancer, autoimmune diseases, pancreatitis, and cataracts |
| AU752059B2 (en) | 1997-10-27 | 2002-09-05 | Dr. Reddy's Laboratories Limited | Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
| WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
| US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
| WO1999016758A1 (en) | 1997-10-27 | 1999-04-08 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
| CA2307820C (en) * | 1997-10-27 | 2007-04-24 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
| US6265401B1 (en) * | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
| EP1082313A1 (en) * | 1998-05-27 | 2001-03-14 | Dr. Reddy's Research Foundation | Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
| HUP0104240A2 (en) | 1998-09-17 | 2002-03-28 | Bristol-Myers Squibb Company | Method for treating atherosclerosis employing an ap2 inhibitor and combination |
| US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
| US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
| AU6325699A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
| WO2000023445A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
| JP2002527503A (en) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their preparation and use |
| US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
| AU6190299A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
| US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
| EP1123297A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
| EP1123267A1 (en) | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
| US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
| BR9914438A (en) * | 1998-10-29 | 2001-06-26 | Reddy Research Foundation | Improved process for preparing new anti-diabetic agents |
| US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
| AU3957800A (en) * | 1999-04-16 | 2000-11-02 | Dr. Reddy's Research Foundation | Crystalline r- guanidines, arginine or (l) -arginine (2(s)) -2- ethoxy -3-(4- (2-(10(h) -phenoxazin -10-yl)ethoxy}phenyl)propanoate |
| AU3958100A (en) | 1999-04-20 | 2000-11-02 | Novo Nordisk A/S | New compounds, their preparation and use |
| IL145789A0 (en) * | 1999-04-20 | 2002-07-25 | Novo Nordisk As | Derivatives of propionic acid, their preparation and pharmaceutical compositions containing them |
| US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
| JP2002542237A (en) * | 1999-04-20 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their production and use |
| US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
| US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
| WO2000066572A1 (en) * | 1999-04-28 | 2000-11-09 | Dr. Reddy's Research Foundation | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents |
| US6417212B1 (en) | 1999-08-27 | 2002-07-09 | Eli Lilly & Company | Modulators of peroxisome proliferator activated receptors |
| KR100649304B1 (en) * | 2000-01-19 | 2006-11-24 | 카딜라 헬스케어 리미티드 | Novel compounds having hypolipedemic, hypochoresteremic activities, process for their preparation and pharmaceutical compositions containg them |
| US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
| CN1396904A (en) * | 2000-01-28 | 2003-02-12 | 诺沃挪第克公司 | Novel compound, their preparation and use |
| US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
| US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
| AU2001263083A1 (en) * | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4h-benzo(1,4)oxazin-3-ones |
| WO2001087860A2 (en) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Novel benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment |
| US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
| AU2001261503A1 (en) * | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators |
| US6987123B2 (en) * | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
| US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
| US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
| US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
| AU2002351752A1 (en) | 2001-12-29 | 2003-07-30 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
| US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
| US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
| US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
| EP2154131A4 (en) * | 2007-04-26 | 2011-09-21 | Pharmafrontier Co Ltd | G protein-coupled receptor inhibitor and pharmaceutical product |
| CA2825456C (en) | 2011-01-31 | 2016-01-05 | Cadila Healthcare Limited | Treatment for lipodystrophy |
| CN105377246B (en) | 2013-04-22 | 2018-03-20 | 卡迪拉保健有限公司 | For non-alcohol fatty liver (NAFLD) new compositions |
| EP3004053B1 (en) | 2013-05-30 | 2021-03-24 | Cadila Healthcare Limited | A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities |
| TW201636015A (en) | 2013-07-05 | 2016-10-16 | 卡地拉保健有限公司 | Synergistic compositions |
| IN2013MU02470A (en) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
| WO2015033357A2 (en) | 2013-09-06 | 2015-03-12 | Cadila Healthcare Limited | An improved process for the preparation of pyrrole derivatives |
| US10385017B2 (en) | 2015-10-14 | 2019-08-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
| BR112019011740A2 (en) | 2016-12-09 | 2019-10-29 | Cadila Healthcare Ltd | Pharmaceutical composition and method for the treatment of primary biliary cholangitis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
| PL176885B1 (en) * | 1992-07-03 | 1999-08-31 | Smithkline Beecham Plc | Pharmaceutic composition |
-
1995
- 1995-06-07 BR BR9508468A patent/BR9508468A/en unknown
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/en active Search and Examination
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/en active
- 1995-07-27 IL IL11475995A patent/IL114759A/en unknown
- 1995-07-27 MA MA23972A patent/MA23632A1/en unknown
- 1995-07-27 IL IL12552595A patent/IL125525A/en unknown
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/en not_active Application Discontinuation
- 1995-07-28 EP EP95930436A patent/EP0772605A1/en not_active Withdrawn
- 1995-07-28 CA CA002196079A patent/CA2196079A1/en not_active Abandoned
- 1995-07-28 PL PL95318766A patent/PL318766A1/en unknown
- 1995-07-28 SK SK122-97A patent/SK12297A3/en unknown
- 1995-07-28 HU HU9700264A patent/HUT76637A/en unknown
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/en unknown
- 1995-07-28 MX MX9700763A patent/MX9700763A/en unknown
-
1997
- 1997-01-28 FI FI970357A patent/FI970357A/en unknown
- 1997-01-28 NO NO970373A patent/NO307827B1/en not_active IP Right Cessation
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AP776A (en) | 1999-10-28 |
| IL125525A (en) | 2000-02-29 |
| MA23632A1 (en) | 1996-04-01 |
| FI970357A (en) | 1997-03-26 |
| MX9700763A (en) | 1997-05-31 |
| IL114759A0 (en) | 1995-12-31 |
| FI970357A0 (en) | 1997-01-28 |
| CA2196079A1 (en) | 1996-02-15 |
| IL114759A (en) | 1999-10-28 |
| CZ25497A3 (en) | 1997-09-17 |
| WO1996004261A1 (en) | 1996-02-15 |
| IL125525A0 (en) | 1999-03-12 |
| PL318766A1 (en) | 1997-07-07 |
| OA10470A (en) | 2002-04-08 |
| NO970373L (en) | 1997-03-18 |
| HUT76637A (en) | 1997-10-28 |
| DZ1916A1 (en) | 2002-02-17 |
| NO307827B1 (en) | 2000-06-05 |
| AP9700918A0 (en) | 1997-01-31 |
| EP0772605A1 (en) | 1997-05-14 |
| WO1996004260A1 (en) | 1996-02-15 |
| SK12297A3 (en) | 1997-08-06 |
| BR9508468A (en) | 1997-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN JANUARY 2003 |