PL318766A1 - Derivatives of benzoxazoles and pyridines useful in treating diabetes of type ii - Google Patents
Derivatives of benzoxazoles and pyridines useful in treating diabetes of type iiInfo
- Publication number
- PL318766A1 PL318766A1 PL95318766A PL31876695A PL318766A1 PL 318766 A1 PL318766 A1 PL 318766A1 PL 95318766 A PL95318766 A PL 95318766A PL 31876695 A PL31876695 A PL 31876695A PL 318766 A1 PL318766 A1 PL 318766A1
- Authority
- PL
- Poland
- Prior art keywords
- benzoxazoles
- derivatives
- type
- treating diabetes
- pyridines useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
PCT/GB1995/001323 WO1996004261A1 (en) | 1994-07-29 | 1995-06-07 | Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
PL318766A1 true PL318766A1 (en) | 1997-07-07 |
Family
ID=27267309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL95318766A PL318766A1 (en) | 1994-07-29 | 1995-07-28 | Derivatives of benzoxazoles and pyridines useful in treating diabetes of type ii |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0772605A1 (en) |
AP (1) | AP776A (en) |
BR (1) | BR9508468A (en) |
CA (1) | CA2196079A1 (en) |
CZ (1) | CZ25497A3 (en) |
DZ (1) | DZ1916A1 (en) |
FI (1) | FI970357A (en) |
HU (1) | HUT76637A (en) |
IL (3) | IL114759A (en) |
MA (1) | MA23632A1 (en) |
MX (1) | MX9700763A (en) |
NO (1) | NO307827B1 (en) |
OA (1) | OA10470A (en) |
PL (1) | PL318766A1 (en) |
SK (1) | SK12297A3 (en) |
WO (2) | WO1996004261A1 (en) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
WO1997037970A1 (en) * | 1996-04-04 | 1997-10-16 | Sankyo Company, Limited | Phenylalkylcarboxylic acid derivatives |
US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
KR20010030881A (en) | 1997-10-02 | 2001-04-16 | 가와무라 요시부미 | Amidocarboxylic acid derivatives |
US6054453A (en) | 1997-10-27 | 2000-04-25 | Redd's Research Foundation | Tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them |
WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
HUP0101110A3 (en) | 1997-10-27 | 2002-06-28 | Reddys Lab Ltd Dr | Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
US6130214A (en) | 1997-10-27 | 2000-10-10 | Dr. Reddy's Research Foundation | Benzothiazin and benzoxazin derivatives; their preparation and uses |
US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
US6265401B1 (en) * | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
PL341795A1 (en) * | 1998-05-27 | 2001-05-07 | Reddy Research Foundation | Bicycle compounds, process for obtaining them and pharmacological compositions containing such compounds |
EP1121129B1 (en) | 1998-09-17 | 2008-09-03 | Bristol-Myers Squibb Company | METHOD FOR TREATING DIABETES EMPLOYING AN aP2 INHIBITOR AND ASSOCIATED COMBINATIONS |
JP2002527520A (en) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their production and use |
EP1123269A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
AU6190299A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
JP2002527516A (en) * | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their production and use |
WO2000023416A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
AU6190199A (en) | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
BR9914438A (en) | 1998-10-29 | 2001-06-26 | Reddy Research Foundation | Improved process for preparing new anti-diabetic agents |
AU3957800A (en) * | 1999-04-16 | 2000-11-02 | Dr. Reddy's Research Foundation | Crystalline r- guanidines, arginine or (l) -arginine (2(s)) -2- ethoxy -3-(4- (2-(10(h) -phenoxazin -10-yl)ethoxy}phenyl)propanoate |
US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
AU3958100A (en) | 1999-04-20 | 2000-11-02 | Novo Nordisk A/S | New compounds, their preparation and use |
US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
JP2002542237A (en) * | 1999-04-20 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their production and use |
JP2002542218A (en) * | 1999-04-20 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their manufacture and use |
US7348426B1 (en) * | 1999-04-28 | 2008-03-25 | Dr. Reddy's Laboraties Limited | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents |
WO2001016120A1 (en) | 1999-08-27 | 2001-03-08 | Eli Lilly And Company | Biaryl-oxa(thia)zole derivatives and their use as ppars modulators |
HU230609B1 (en) * | 2000-01-19 | 2017-03-28 | Cadila Healthcare Ltd. | Compounds having hypolipidemic and hypocholesterolemic activities, process for their preparation and pharmaceutical compositions containing them and their use, intermediates |
US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
JP2003520839A (en) * | 2000-01-28 | 2003-07-08 | ノボ ノルディスク アクティーゼルスカブ | New compounds, their production and use |
US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
US6599899B2 (en) | 2000-05-12 | 2003-07-29 | Ortho-Mcneil Pharmaceutical, Inc. | Benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment |
EP1280784B1 (en) | 2000-05-12 | 2007-06-27 | Ortho-McNeil Pharmaceutical, Inc. | Biologically active 4h-benzo 1,4|oxazin-3-ones |
AU2001261503A1 (en) * | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators |
US6987123B2 (en) | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
JP2005518408A (en) | 2001-12-29 | 2005-06-23 | ノボ ノルディスク アクティーゼルスカブ | Combination use of GLP-1 compounds and other drugs to treat dyslipidemia |
US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
EP2154131A4 (en) * | 2007-04-26 | 2011-09-21 | Pharmafrontier Co Ltd | G protein-coupled receptor inhibitor and pharmaceutical product |
MY191100A (en) | 2011-01-31 | 2022-05-30 | Cadila Healthcare Ltd | Treatment for lipodystrophy |
SG11201506218UA (en) | 2013-04-22 | 2015-09-29 | Cadila Healthcare Ltd | A novel composition for nonalcoholic fatty liver disease (nafld) |
WO2014195967A2 (en) | 2013-05-30 | 2014-12-11 | Cadila Healthcare Limited | A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities |
TW201513857A (en) | 2013-07-05 | 2015-04-16 | Cadila Healthcare Ltd | Synergistic compositions |
IN2013MU02470A (en) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
IN2013MU02905A (en) | 2013-09-06 | 2015-07-03 | Cadila Healthcare Ltd | |
WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
WO2018104916A1 (en) | 2016-12-09 | 2018-06-14 | Cadila Healthcare Limited | Treatment for primary biliary cholangitis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
JPH07508747A (en) * | 1992-07-03 | 1995-09-28 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | Pharmaceutical heterocyclic compounds |
-
1995
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/en active Search and Examination
- 1995-06-07 BR BR9508468A patent/BR9508468A/en unknown
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/en active
- 1995-07-27 MA MA23972A patent/MA23632A1/en unknown
- 1995-07-27 IL IL11475995A patent/IL114759A/en unknown
- 1995-07-27 IL IL12552595A patent/IL125525A/en unknown
- 1995-07-28 CA CA002196079A patent/CA2196079A1/en not_active Abandoned
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/en not_active Application Discontinuation
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 HU HU9700264A patent/HUT76637A/en unknown
- 1995-07-28 PL PL95318766A patent/PL318766A1/en unknown
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/en unknown
- 1995-07-28 SK SK122-97A patent/SK12297A3/en unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/en not_active Withdrawn
- 1995-07-28 MX MX9700763A patent/MX9700763A/en unknown
-
1997
- 1997-01-28 FI FI970357A patent/FI970357A/en unknown
- 1997-01-28 NO NO970373A patent/NO307827B1/en not_active IP Right Cessation
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
AP776A (en) | 1999-10-28 |
NO307827B1 (en) | 2000-06-05 |
IL125525A0 (en) | 1999-03-12 |
CA2196079A1 (en) | 1996-02-15 |
SK12297A3 (en) | 1997-08-06 |
NO970373L (en) | 1997-03-18 |
HUT76637A (en) | 1997-10-28 |
WO1996004261A1 (en) | 1996-02-15 |
DZ1916A1 (en) | 2002-02-17 |
FI970357A (en) | 1997-03-26 |
WO1996004260A1 (en) | 1996-02-15 |
BR9508468A (en) | 1997-11-25 |
CZ25497A3 (en) | 1997-09-17 |
IL125525A (en) | 2000-02-29 |
FI970357A0 (en) | 1997-01-28 |
OA10470A (en) | 2002-04-08 |
MA23632A1 (en) | 1996-04-01 |
MX9700763A (en) | 1997-05-31 |
NO970373D0 (en) | 1997-01-28 |
IL114759A0 (en) | 1995-12-31 |
IL114759A (en) | 1999-10-28 |
AP9700918A0 (en) | 1997-01-31 |
EP0772605A1 (en) | 1997-05-14 |
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