FI965020A0 - Nya föreningar, förfaranden för deras framställning och antitumörmedel - Google Patents

Nya föreningar, förfaranden för deras framställning och antitumörmedel

Info

Publication number
FI965020A0
FI965020A0 FI965020A FI965020A FI965020A0 FI 965020 A0 FI965020 A0 FI 965020A0 FI 965020 A FI965020 A FI 965020A FI 965020 A FI965020 A FI 965020A FI 965020 A0 FI965020 A0 FI 965020A0
Authority
FI
Finland
Prior art keywords
hydrogen atom
processes
preparation
tumor agents
group
Prior art date
Application number
FI965020A
Other languages
English (en)
Finnish (fi)
Other versions
FI112485B (sv
FI965020A (sv
Inventor
Kyoji Tomita
Katsumi Chiba
Shigeki Kashimoto
Koh-Ichiro Shibamori
Yasunori Tsuzuki
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of FI965020A0 publication Critical patent/FI965020A0/sv
Publication of FI965020A publication Critical patent/FI965020A/sv
Application granted granted Critical
Publication of FI112485B publication Critical patent/FI112485B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI965020A 1994-06-14 1996-12-13 Nya 1,4-dihydro-4-oxo-1,8-naftyridinderivat, förfarande för framställning av den och antitumörmedel FI112485B (sv)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP15657894 1994-06-14
JP19792194 1994-07-28
JP30691494 1994-11-15
JP33995694 1994-12-28
JP8170595 1995-03-13
PCT/JP1995/001110 WO1995034559A1 (fr) 1994-06-14 1995-06-06 Nouveau compose, son procede de production et agent antitumoral

Publications (3)

Publication Number Publication Date
FI965020A0 true FI965020A0 (sv) 1996-12-13
FI965020A FI965020A (sv) 1996-12-16
FI112485B FI112485B (sv) 2003-12-15

Family

ID=27524935

Family Applications (1)

Application Number Title Priority Date Filing Date
FI965020A FI112485B (sv) 1994-06-14 1996-12-13 Nya 1,4-dihydro-4-oxo-1,8-naftyridinderivat, förfarande för framställning av den och antitumörmedel

Country Status (27)

Country Link
US (1) US5817669A (sv)
EP (1) EP0787726B1 (sv)
JP (1) JP3391796B2 (sv)
KR (1) KR100350921B1 (sv)
CN (1) CN1053668C (sv)
AT (1) ATE209645T1 (sv)
AU (1) AU679859B2 (sv)
BR (1) BR9508037A (sv)
CA (1) CA2192824C (sv)
CZ (1) CZ292631B6 (sv)
DE (1) DE69524251T2 (sv)
DK (1) DK0787726T3 (sv)
ES (1) ES2163512T3 (sv)
FI (1) FI112485B (sv)
HK (1) HK1000495A1 (sv)
HU (1) HU220072B (sv)
MX (1) MX9606331A (sv)
NO (1) NO307255B1 (sv)
NZ (1) NZ287139A (sv)
PL (1) PL181867B1 (sv)
PT (1) PT787726E (sv)
RO (1) RO117793B1 (sv)
RU (1) RU2151770C1 (sv)
SI (1) SI0787726T1 (sv)
SK (1) SK281341B6 (sv)
TW (1) TW319769B (sv)
WO (1) WO1995034559A1 (sv)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1432711A1 (en) 2001-09-26 2004-06-30 Bayer Corporation 1,6-naphthyridine derivatives as antidiabetics
US6802423B2 (en) * 2002-02-20 2004-10-12 Trans Global Foods, Inc. Disposable food delivery apparatus
WO2004091627A2 (en) * 2003-04-07 2004-10-28 Cylene Pharmaceuticals, Inc. Heterocyclic substituted 1,4-dihydro-4-oxo-1,8-naphthpyridine analogs
CN100410249C (zh) * 2003-09-10 2008-08-13 杏林制药株式会社 7-(4-取代-3-环丙基氨基甲基-1-吡咯烷基)喹诺酮羧酸衍生物
DE10352979A1 (de) * 2003-11-13 2005-06-09 Merck Patent Gmbh Pyridopyrimidinone
US7989468B2 (en) 2004-03-15 2011-08-02 Sunesis Pharmaceuticals, Inc. Methods of using SNS-595
AU2013201203C1 (en) * 2004-03-15 2015-04-23 Sumitomo Dainippon Pharma Co., Ltd. Sns-595 and methods of using the same
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
CA2619663A1 (en) * 2005-08-19 2007-02-22 Cylene Pharmaceuticals, Inc. Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof
US8580814B2 (en) * 2006-04-03 2013-11-12 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
AU2013219242C1 (en) * 2005-09-02 2016-09-22 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
AU2006287149B2 (en) * 2005-09-02 2013-05-23 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
CN104873502A (zh) * 2005-09-02 2015-09-02 逊尼希思制药公司 使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸治疗癌症的方法
KR20140057409A (ko) * 2005-09-02 2014-05-12 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한 (＋)-1,4-디히드로-7-［(3ｓ,4ｓ)-3-메톡시-4-(메틸아미노)-1-피롤리디닐］-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
CN101305000A (zh) * 2005-09-14 2008-11-12 詹森药业有限公司 作为c-fms激酶抑制剂的5-氧代-5,8-二氢-吡啶并-嘧啶类
TW200800983A (en) 2005-09-14 2008-01-01 Janssen Pharmaceutica Nv 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase
US7642270B2 (en) 2005-09-14 2010-01-05 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
JP2009539994A (ja) 2006-06-12 2009-11-19 サネシス ファーマシューティカルズ， インコーポレイテッド 癌の治療のための化合物及び組成物
US20100048609A1 (en) * 2006-08-01 2010-02-25 Jacobs Jeffrey W Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
CA2659861A1 (en) * 2006-08-02 2008-02-07 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of certain hematologic disorders
CN103720701A (zh) * 2007-10-22 2014-04-16 逊尼希思制药公司 在联合治疗中使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸的方法
EP2649997B1 (en) * 2007-12-10 2019-01-23 Sunesis Pharmaceuticals, Inc. (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for use in the treatment of myelodyspastic syndrome
EP3284745A1 (en) * 2008-12-31 2018-02-21 Sunesis Pharmaceuticals, Inc. Composition of (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
SG10201400258SA (en) 2009-02-27 2014-05-29 Sunesis Pharmaceuticals Inc Methods Of Using SNS-595 For Treatment Of Cancer Subjects With Reduced BRCA2 Activity
UA110465C2 (en) * 2009-09-04 2016-01-12 Sunesis Pharmaceutecals Inc Stable sns-595 composition
WO2011056566A2 (en) * 2009-10-26 2011-05-12 Sunesis Pharmaceuticals, Inc. Compounds and methods for treatment of cancer
CN105130967B (zh) * 2011-05-13 2018-04-17 阵列生物制药公司 作为trka激酶抑制剂的吡咯烷基脲和吡咯烷基硫脲化合物
CN103497186B (zh) * 2013-09-24 2015-02-25 浙江司太立制药股份有限公司 含有烷氧亚氨基取代的萘啶酮羧酸衍生物及其制备方法
US11286255B2 (en) 2017-03-24 2022-03-29 Wakunaga Pharmaceutical Co., Ltd. Pyridone carboxylic acid derivative or salt thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
EP0154780B1 (en) * 1984-01-26 1990-04-11 Abbott Laboratories Quinoline antibacterial compounds
JPS61152682A (ja) * 1984-12-27 1986-07-11 Dainippon Pharmaceut Co Ltd ピリドンカルボン酸誘導体、そのエステルおよびその塩
JPS61251667A (ja) * 1985-04-30 1986-11-08 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環化合物
IE60420B1 (en) * 1985-06-13 1994-07-13 Schering Corp Polycyclic quinoline, naphthyridine and pyrazinopyridine derivatives
EP0226624A1 (en) * 1985-06-14 1987-07-01 The Upjohn Company Cyclopentapyrazole and tetrahydroindazole compounds
JPS6233176A (ja) * 1985-08-05 1987-02-13 Toyama Chem Co Ltd １，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩
JP2704428B2 (ja) * 1988-06-15 1998-01-26 富山化学工業株式会社 キノロンカルボン酸誘導体またはその塩
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
JPH06233176A (ja) * 1993-01-29 1994-08-19 Sony Corp ビデオカメラ

Also Published As

Publication number Publication date
DK0787726T3 (da) 2002-02-11
CZ292631B6 (cs) 2003-11-12
AU2576795A (en) 1996-01-05
RU2151770C1 (ru) 2000-06-27
HU220072B (hu) 2001-10-28
CN1053668C (zh) 2000-06-21
EP0787726A1 (en) 1997-08-06
ATE209645T1 (de) 2001-12-15
WO1995034559A1 (fr) 1995-12-21
MX9606331A (es) 1997-03-29
US5817669A (en) 1998-10-06
CA2192824C (en) 2006-11-07
SK157496A3 (en) 1997-08-06
RO117793B1 (ro) 2002-07-30
EP0787726A4 (sv) 1997-08-06
DE69524251T2 (de) 2002-07-11
KR100350921B1 (ko) 2002-11-18
NO965305L (no) 1997-02-04
HK1000495A1 (en) 2002-07-19
SK281341B6 (sk) 2001-02-12
NO965305D0 (no) 1996-12-11
DE69524251D1 (de) 2002-01-10
PL181867B1 (pl) 2001-09-28
ES2163512T3 (es) 2002-02-01
NZ287139A (en) 1997-07-27
BR9508037A (pt) 1997-09-16
PL317726A1 (en) 1997-04-28
HU9603455D0 (en) 1997-02-28
AU679859B2 (en) 1997-07-10
HUT75777A (en) 1997-05-28
JP3391796B2 (ja) 2003-03-31
EP0787726B1 (en) 2001-11-28
FI112485B (sv) 2003-12-15
FI965020A (sv) 1996-12-16
NO307255B1 (no) 2000-03-06
CZ364396A3 (en) 1997-06-11
CN1158614A (zh) 1997-09-03
PT787726E (pt) 2002-04-29
CA2192824A1 (en) 1995-12-21
TW319769B (sv) 1997-11-11
SI0787726T1 (en) 2002-04-30

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Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: DAINIPPON SUMITOMO PHARMA CO., LTD.

Free format text: DAINIPPON SUMITOMO PHARMA CO., LTD.

MA Patent expired