FI912873A - Ny polypeptidfoerening och foerfarande foer dess framstaellning. - Google Patents

Ny polypeptidfoerening och foerfarande foer dess framstaellning. Download PDF

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Publication number
FI912873A
FI912873A FI912873A FI912873A FI912873A FI 912873 A FI912873 A FI 912873A FI 912873 A FI912873 A FI 912873A FI 912873 A FI912873 A FI 912873A FI 912873 A FI912873 A FI 912873A
Authority
FI
Finland
Prior art keywords
hydrogen
alkoxy
chem
halogen
polypeptidfoerening
Prior art date
Application number
FI912873A
Other languages
English (en)
Other versions
FI912873A0 (fi
Inventor
Toshiro Iwamoto
Akihiko Fujie
Kumiko Nitta
Yasuhisa Tsurumi
Nobuharu Shigematsu
Chiyoshi Kasahara
Motohiro Hino
Masakuni Okuhara
Kazuo Sakane
Kohji Kawabata
Hidenori Ohki
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909013558A external-priority patent/GB9013558D0/en
Priority claimed from GB909023666A external-priority patent/GB9023666D0/en
Priority claimed from GB919101552A external-priority patent/GB9101552D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of FI912873A0 publication Critical patent/FI912873A0/fi
Publication of FI912873A publication Critical patent/FI912873A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K11/00Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
FI912873A 1990-06-18 1991-06-14 Ny polypeptidfoerening och foerfarande foer dess framstaellning. FI912873A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909013558A GB9013558D0 (en) 1990-06-18 1990-06-18 New polypeptide compound and a process for preparation thereof
GB909023666A GB9023666D0 (en) 1990-10-31 1990-10-31 Polypeptide compound and a process for preparation thereof
GB919101552A GB9101552D0 (en) 1991-01-24 1991-01-24 New polypeptide compound and a process for preparation thereof

Publications (2)

Publication Number Publication Date
FI912873A0 FI912873A0 (fi) 1991-06-14
FI912873A true FI912873A (fi) 1991-12-19

Family

ID=27265144

Family Applications (1)

Application Number Title Priority Date Filing Date
FI912873A FI912873A (fi) 1990-06-18 1991-06-14 Ny polypeptidfoerening och foerfarande foer dess framstaellning.

Country Status (20)

Country Link
US (1) US5376634A (fi)
EP (2) EP0729974A1 (fi)
JP (1) JP3307410B2 (fi)
KR (1) KR100199535B1 (fi)
CN (1) CN1040541C (fi)
AT (1) ATE143671T1 (fi)
AU (1) AU651347B2 (fi)
CA (1) CA2044746C (fi)
DE (1) DE69122432T2 (fi)
DK (1) DK0462531T3 (fi)
ES (1) ES2093658T3 (fi)
FI (1) FI912873A (fi)
GR (1) GR3021780T3 (fi)
HU (2) HUT58108A (fi)
IE (2) IE912046A1 (fi)
IL (1) IL98506A (fi)
NO (1) NO912347L (fi)
OA (1) OA09369A (fi)
PT (1) PT98023B (fi)
RU (1) RU2108342C1 (fi)

Families Citing this family (48)

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GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
IE912046A1 (en) 1990-06-18 1991-12-18 Fujisawa Pharmaceutical Co New polypeptide compound and a process for preparation¹thereof
US5428009A (en) * 1990-07-16 1995-06-27 Merck & Co., Inc. Lipopeptide derivatives
USH1638H (en) * 1990-11-08 1997-03-04 Furuta; Takahisa Use of the polypeptide compound
US5385884A (en) * 1991-08-27 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5965525A (en) * 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
US6384013B1 (en) 1992-03-19 2002-05-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
AU674233B2 (en) * 1993-05-04 1996-12-12 Merck & Co., Inc. Cyclohexapeptidyl aminoalkyl ethers
AU681119B2 (en) * 1993-05-17 1997-08-21 Fujisawa Pharmaceutical Co., Ltd. New polypeptide compound and a process for preparation thereof
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
CA2202058C (en) * 1994-10-07 2007-11-06 Hidenori Ohki Cyclic hexapeptides having antibiotic activity
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
DE69615535T2 (de) * 1995-01-26 2002-05-02 Merck & Co Inc Neue fungizide cyclohexapeptide
US5646111A (en) * 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5629290A (en) * 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5618787A (en) * 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5786325A (en) * 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
WO1997047738A1 (fr) 1996-06-13 1997-12-18 Fujisawa Pharmaceutical Co., Ltd. Acylase des lipopeptides cycliques
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
WO1999040108A1 (en) 1998-02-09 1999-08-12 Fujisawa Pharmaceutical Co., Ltd. New compound
CN1148361C (zh) * 1998-05-11 2004-05-05 武田药品工业株式会社 羟基亚氨基链烷酸衍生物
AU765660B2 (en) 1998-08-20 2003-09-25 Eli Lilly And Company Ring modified cyclic peptide analogs
CA2353930A1 (en) 1998-12-09 2000-06-15 Eli Lilly And Company Purification of echinocandin cyclopeptide compounds
PT1582204E (pt) 1999-03-03 2013-11-25 Lilly Co Eli Formulações farmacêuticas de equinocandina que contêm tensioactivos que formam micelas
PT1155034E (pt) 1999-03-03 2007-01-31 Lilly Co Eli Formação e permuta aniónica de sais de amónio internos cristalinos de equinocandina b
CN1345333A (zh) 1999-03-03 2002-04-17 伊莱利利公司 棘白菌素/糖类复合物
WO2000051567A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
AUPP999799A0 (en) 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
WO2002068456A1 (en) * 2001-02-26 2002-09-06 Fujisawa Pharmaceutical Co., Ltd. Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs
KR20010098986A (ko) * 2001-07-27 2001-11-09 김종군 바르는 단열재(temp-coat)
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
US7459290B1 (en) 2004-03-30 2008-12-02 Iowa State University Research Foundation, Inc. Methods of using functional 30S subunits
WO2010064219A1 (en) 2008-12-04 2010-06-10 Ranbaxy Laboratories Limited Process for the preparation of a novel intermediate for caspofungin
CN102432674B (zh) 2010-09-29 2014-01-22 上海天伟生物制药有限公司 一种环脂肽化合物或其盐的纯化方法
RU2538274C2 (ru) * 2010-09-30 2015-01-10 Шанхай Техвелл Биофармасьютикал Ко., Лтд. Способ очистки циклопептидных соединений или их солей
CN102533551B (zh) * 2010-12-15 2013-10-09 上海天伟生物制药有限公司 一种肽类抗生素的高产菌株及其制备方法和用途
CN102618604B (zh) * 2011-01-31 2014-09-03 上海天伟生物制药有限公司 一种环脂肽化合物的制备方法
WO2012143293A1 (en) 2011-04-20 2012-10-26 Xellia Pharmaceuticals Aps Method for purification of micafungin
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102659930B (zh) * 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN102627688B (zh) * 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN103387975A (zh) 2012-05-11 2013-11-13 上海天伟生物制药有限公司 一种固定化环脂肽酰基转移酶及其制备方法和用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293482A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company A-30912A Nucleus
CA1159450A (en) * 1979-12-13 1983-12-27 Manuel Debono Process for the preparation of derivatives of cyclic peptide nuclei
US4293484A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912H nucleus
US4293488A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912B nucleus
US4293489A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
CA1182812A (en) * 1979-12-13 1985-02-19 Bernard J. Abbott Process for the preparation of derivatives of cyclic peptide nuclei
DE3689525D1 (de) * 1985-07-17 1994-02-24 Hoechst Ag Neue Polypeptide mit blutgerinnungshemmender Wirkung, Verfahren zu deren Herstellung bzw. Gewinnung, deren Verwendung und diese enthaltende Mittel.
DE3886001T2 (de) * 1987-10-07 1994-05-26 Merck & Co Inc Fungizides Fermentationsprodukt.
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
CA2044249A1 (en) * 1989-10-18 1991-04-19 Shiuan Chen Stable mammalian cell lines that express aromatase
GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
IE912046A1 (en) 1990-06-18 1991-12-18 Fujisawa Pharmaceutical Co New polypeptide compound and a process for preparation¹thereof
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii

Also Published As

Publication number Publication date
JPH04352799A (ja) 1992-12-07
CA2044746C (en) 2001-08-07
GR3021780T3 (en) 1997-02-28
EP0729974A1 (en) 1996-09-04
CN1059729A (zh) 1992-03-25
IE912046A1 (en) 1991-12-18
KR100199535B1 (ko) 1999-06-15
US5376634A (en) 1994-12-27
HU912014D0 (en) 1991-12-30
AU7843591A (en) 1992-01-16
ATE143671T1 (de) 1996-10-15
RU2108342C1 (ru) 1998-04-10
IL98506A0 (en) 1992-07-15
NO912347D0 (no) 1991-06-17
JP3307410B2 (ja) 2002-07-24
IE990233A1 (en) 2000-11-15
HU211740A9 (en) 1995-12-28
CA2044746A1 (en) 1991-12-19
DE69122432T2 (de) 1997-03-20
CN1040541C (zh) 1998-11-04
NO912347L (no) 1991-12-19
HUT58108A (en) 1992-01-28
EP0462531A3 (en) 1992-11-04
KR920000788A (ko) 1992-01-29
OA09369A (en) 1992-09-15
PT98023A (pt) 1992-03-31
ES2093658T3 (es) 1997-01-01
EP0462531A2 (en) 1991-12-27
DK0462531T3 (da) 1996-11-18
EP0462531B1 (en) 1996-10-02
IL98506A (en) 1996-09-12
AU651347B2 (en) 1994-07-21
FI912873A0 (fi) 1991-06-14
DE69122432D1 (de) 1996-11-07
PT98023B (pt) 1998-11-30

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