FI20000635A0 - COMT-inhibiittoreiden käyttö analgeettina - Google Patents

COMT-inhibiittoreiden käyttö analgeettina

Info

Publication number
FI20000635A0
FI20000635A0 FI20000635A FI20000635A FI20000635A0 FI 20000635 A0 FI20000635 A0 FI 20000635A0 FI 20000635 A FI20000635 A FI 20000635A FI 20000635 A FI20000635 A FI 20000635A FI 20000635 A0 FI20000635 A0 FI 20000635A0
Authority
FI
Finland
Prior art keywords
analgesic
comt inhibitors
comt
inhibitors
pain
Prior art date
Application number
FI20000635A
Other languages
English (en)
Swedish (sv)
Inventor
Paeivi Aho
Inge-Britt Linden
Original Assignee
Orion Yhtymae Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oyj filed Critical Orion Yhtymae Oyj
Priority to FI20000635A priority Critical patent/FI20000635A0/fi
Publication of FI20000635A0 publication Critical patent/FI20000635A0/fi
Priority to EP01919513A priority patent/EP1263425B1/en
Priority to AU2001246600A priority patent/AU2001246600A1/en
Priority to CA002403352A priority patent/CA2403352C/en
Priority to JP2001566647A priority patent/JP4874489B2/ja
Priority to PCT/FI2001/000265 priority patent/WO2001068083A1/en
Priority to AT01919513T priority patent/ATE256461T1/de
Priority to DE60101559T priority patent/DE60101559T2/de
Priority to US10/221,497 priority patent/US6723754B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
FI20000635A 2000-03-17 2000-03-17 COMT-inhibiittoreiden käyttö analgeettina FI20000635A0 (fi)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FI20000635A FI20000635A0 (fi) 2000-03-17 2000-03-17 COMT-inhibiittoreiden käyttö analgeettina
EP01919513A EP1263425B1 (en) 2000-03-17 2001-03-16 Use of comt inhibitors as analgesics
AU2001246600A AU2001246600A1 (en) 2000-03-17 2001-03-16 Use of comt inhibitors as analgesics
CA002403352A CA2403352C (en) 2000-03-17 2001-03-16 Use of comt inhibitors as analgesics
JP2001566647A JP4874489B2 (ja) 2000-03-17 2001-03-16 Ｃｏｍｔ阻害剤の鎮痛剤としての用途
PCT/FI2001/000265 WO2001068083A1 (en) 2000-03-17 2001-03-16 Use of comt inhibitors as analgesics
AT01919513T ATE256461T1 (de) 2000-03-17 2001-03-16 Benutzung von comt-inhibitoren als analgetika
DE60101559T DE60101559T2 (de) 2000-03-17 2001-03-16 Benutzung von comt-inhibitoren als analgetika
US10/221,497 US6723754B2 (en) 2000-03-17 2001-03-16 Use of COMT inhibitors as analgesics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20000635A FI20000635A0 (fi) 2000-03-17 2000-03-17 COMT-inhibiittoreiden käyttö analgeettina

Publications (1)

Publication Number Publication Date
FI20000635A0 true FI20000635A0 (fi) 2000-03-17

Family

ID=8557970

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20000635A FI20000635A0 (fi) 2000-03-17 2000-03-17 COMT-inhibiittoreiden käyttö analgeettina

Country Status (9)

Country Link
US (1) US6723754B2 (fi)
EP (1) EP1263425B1 (fi)
JP (1) JP4874489B2 (fi)
AT (1) ATE256461T1 (fi)
AU (1) AU2001246600A1 (fi)
CA (1) CA2403352C (fi)
DE (1) DE60101559T2 (fi)
FI (1) FI20000635A0 (fi)
WO (1) WO2001068083A1 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1782321A4 (en) 2004-07-23 2009-11-04 Univ North Carolina METHOD AND MATERIALS FOR DETERMINING PAIN SENSITIVITY AND PREDICTING AND TREATING SUFFERING INTERFERENCE
MY148644A (en) * 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
DK1907382T3 (en) 2005-07-26 2015-08-31 Bial Portela & Ca Sa Nitrocatecholderivater comt inhibitors as
EP1845097A1 (en) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
CA2572004A1 (en) * 2006-12-08 2008-06-08 Bernard Charles Sherman Tablets comprising entacapone and crospovidone
AU2007346018A1 (en) 2007-01-31 2008-08-07 Bial - Portela & Ca, S.A. Dosage regimen for COMT inhibitors
WO2009116882A1 (en) 2008-03-17 2009-09-24 Portela & Ca., S.A. Crystal forms of 5- [3- (2, 5-dichloro-4, 6-dimethyl-1-oxy-pyridine-3-yl) [1,2,3] oxadiazol-5-yl] -3-nit robenzene-1, 2-diol
KR102329271B1 (ko) 2009-04-01 2021-11-22 바이알 - 포르텔라 앤드 씨에이 에스에이 니트로카테콜 유도체를 포함하는 제약 제제 및 그의 제조 방법
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
EP2791134B1 (en) 2011-12-13 2019-09-25 BIAL - Portela & Cª S.A. Chemical compound useful as intermediate for preparing a catechol-o-methyltransferase inhibitor
TWI638802B (zh) 2012-05-24 2018-10-21 芬蘭商奧利安公司 兒茶酚ｏ－甲基轉移酶活性抑制化合物
WO2016083863A1 (en) 2014-11-28 2016-06-02 Bial - Portela & Ca, S.A. Medicaments for slowing parkinson's disease
JP2021532133A (ja) 2018-07-25 2021-11-25 オリオン コーポレーション ４，５−ジヒドロキシ−２−（４−メチルベンジル）イソフタロニトリル溶媒和物およびその結晶形
US20220002232A1 (en) 2018-11-09 2022-01-06 Orion Corporation Process for the preparation of 4,5-dihydroxy-2-(4-methylbenzyl)isophthalonitrile
WO2022158991A1 (en) 2021-01-20 2022-07-28 Bial-Portela & Ca., S.A. Treatment of pain associated with parkinson's disease with opicapone in combination with levodopa

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898879A (en) 1959-10-16 1962-06-14 Smith & Nephew Hydrazine derivatives
DK175069B1 (da) * 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
US5236952A (en) * 1986-03-11 1993-08-17 Hoffmann-La Roche Inc. Catechol derivatives
US5283352A (en) 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
FI864875A0 (fi) 1986-11-28 1986-11-28 Orion Yhtymae Oy Nya farmakologiskt aktiva foereningar, dessa innehaollande kompositioner samt foerfarande och mellanprodukter foer anvaendning vid framstaellning av dessa.
YU213587A (en) * 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
US5489614A (en) 1987-11-27 1996-02-06 Orion-Yhtyma Oy Catechol derivatives, their physiologically acceptable salts, esters and use
MTP1031B (en) * 1987-12-24 1990-10-04 Orion Yhtymae Oy New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters
US5470737A (en) * 1993-06-09 1995-11-28 Mayo Foundation For Medical Education And Research Stably-transformed cells expressing human thiopurine methyltransferase
GB9510481D0 (en) 1995-05-24 1995-07-19 Orion Yhtymae Oy New catechol derivatives
GB9626472D0 (en) 1996-12-20 1997-02-05 Aperia Anita C New use of comt inhibitors
US6169103B1 (en) * 1998-03-03 2001-01-02 Warner-Lambert Fluorine-substituted biphenyl butyric acids and their derivatives as inhibitors of matrix metalloproteinases
US6599530B2 (en) * 1998-09-14 2003-07-29 Orion Corporation Oral compacted composition comprising catechol derivatives

Also Published As

Publication number Publication date
US6723754B2 (en) 2004-04-20
WO2001068083A1 (en) 2001-09-20
CA2403352C (en) 2009-05-05
CA2403352A1 (en) 2001-09-20
EP1263425B1 (en) 2003-12-17
ATE256461T1 (de) 2004-01-15
DE60101559T2 (de) 2004-09-16
EP1263425A1 (en) 2002-12-11
JP4874489B2 (ja) 2012-02-15
JP2003526663A (ja) 2003-09-09
DE60101559D1 (de) 2004-01-29
AU2001246600A1 (en) 2001-09-24
US20030069316A1 (en) 2003-04-10

Similar Documents

Publication Publication Date Title
FI20000635A0 (fi) COMT-inhibiittoreiden käyttö analgeettina
CY1109229T1 (el) Χρηση σπογγοσινης (2-μεθοξυαδενοσινης) για τη θεραπεια πονου, συγκεκριμενα υπερευαισθησιας στο πονο
TR200200204T2 (tr) MEK inhibitörleri kullanılarak kronik ağrının tedavi edilmesi.
MY138059A (en) Use of ikb-kinase inhibitors in pain therapy
MXPA05005223A (es) Diaminotriazoles utiles como inhibidores de proteinas cinasas.
IS8913A (is) Afleiður 4-tetrazólýl-4-fenýlpiperidíns til þess að meðhöndla verk
DK1420801T3 (da) Anvendelse af fucaner til behandling af adhæsioner, arthritis og psoreasis
EA200300375A1 (ru) Производные 2-амино-2-алкил-4-гексеновой и -гексиновой кислот, которые могут быть использованы в качестве ингибиторов синтетазы оксида азота
NZ515567A (en) Method for treating chronic pain using MEK inhibitors
CY1110385T1 (el) Χρηση αναστολεων της il-18 για τη θεραπεια και/ή προληψη της αθηροσκληρωσης
DE602004017871D1 (de) Zubereitungen zur behandlung von arthritischen erscheinungen
SE0302304D0 (sv) Novel compounds
ATE469886T1 (de) 17beta-hydroxysteroid dehydrogenase typ-3 hemmer zur behandlung von androgen abhängigen erkrankungen
IS6563A (is) Hýdroxýfenýl-píperasinýl-metýl-bensamíðafleiður til að meðhöndla sársauka
IS6574A (is) Kínólinýl-píperidín-4-ýlíden-metýl-bensamíðafleiður til að meðhöndla sársauka
HUP0204551A2 (hu) Eljárás a pikkelysömör kezelésére
EE200300582A (et) IL-18 inhibiitorite kasutamine kesknärvisüsteemi kahjustuste raviks või ennetamiseks
RS95304A (en) New combination fortreating airway disorders
GB9626472D0 (en) New use of comt inhibitors
ATE536874T1 (de) Dreifache monoamin-wiederaufnahmehemmer zur behandlung von chronischen schmerzen
ATE322898T1 (de) Inhibitoren von mycobakterien
DK1455770T3 (da) Anvendelse af norepinephringenoptagelsesinhibitorer til behandling af tic lidelser
ATE302009T1 (de) Ubichinon qn zur behandlung von migräneschmerzen
ATE377586T1 (de) Tripeptidylpeptidaseinhibitoren
DE69904297D1 (de) Neue verwendung von ropivacain zur schmerzbehandlung