DE60101559D1 - Benutzung von comt-inhibitoren als analgetika - Google Patents

Benutzung von comt-inhibitoren als analgetika

Info

Publication number
DE60101559D1
DE60101559D1 DE60101559T DE60101559T DE60101559D1 DE 60101559 D1 DE60101559 D1 DE 60101559D1 DE 60101559 T DE60101559 T DE 60101559T DE 60101559 T DE60101559 T DE 60101559T DE 60101559 D1 DE60101559 D1 DE 60101559D1
Authority
DE
Germany
Prior art keywords
analgetics
comt inhibitors
comt
inhibitors
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60101559T
Other languages
English (en)
Other versions
DE60101559T2 (de
Inventor
Paeivi Aho
Inge-Britt Linden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Oyj filed Critical Orion Oyj
Publication of DE60101559D1 publication Critical patent/DE60101559D1/de
Application granted granted Critical
Publication of DE60101559T2 publication Critical patent/DE60101559T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE60101559T 2000-03-17 2001-03-16 Benutzung von comt-inhibitoren als analgetika Expired - Lifetime DE60101559T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20000635 2000-03-17
FI20000635A FI20000635A0 (fi) 2000-03-17 2000-03-17 COMT-inhibiittoreiden käyttö analgeettina
PCT/FI2001/000265 WO2001068083A1 (en) 2000-03-17 2001-03-16 Use of comt inhibitors as analgesics

Publications (2)

Publication Number Publication Date
DE60101559D1 true DE60101559D1 (de) 2004-01-29
DE60101559T2 DE60101559T2 (de) 2004-09-16

Family

ID=8557970

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60101559T Expired - Lifetime DE60101559T2 (de) 2000-03-17 2001-03-16 Benutzung von comt-inhibitoren als analgetika

Country Status (9)

Country Link
US (1) US6723754B2 (de)
EP (1) EP1263425B1 (de)
JP (1) JP4874489B2 (de)
AT (1) ATE256461T1 (de)
AU (1) AU2001246600A1 (de)
CA (1) CA2403352C (de)
DE (1) DE60101559T2 (de)
FI (1) FI20000635A0 (de)
WO (1) WO2001068083A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2484780A1 (de) * 2004-07-23 2012-08-08 The University of North Carolina At Chapel Hill Verfahren und Materialien zur Bestimmung der Schmerzempfindlichkeit und Vorhersage und Behandlung zugehöriger Störungen
MY148644A (en) * 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
AU2006272978B2 (en) 2005-07-26 2012-06-07 Bial - Portela & Ca, S.A. Nitrocatechol derivatives as COMT inhibitors
EP1845097A1 (de) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazolderivate als COMT Inihibitoren
CA2572004A1 (en) * 2006-12-08 2008-06-08 Bernard Charles Sherman Tablets comprising entacapone and crospovidone
RU2518483C2 (ru) 2007-01-31 2014-06-10 Биал-Портела Энд Ка, С.А. Режим дозирования ингибиторов комт
JP2011514380A (ja) 2008-03-17 2011-05-06 バイアル−ポルテラ アンド シーエー，エス．エー． ５−［３−（２，５−ジクロロ−４，６−ジメチル−１−オキシ−ピリジン−３−イル）［１，２，４］オキサジアゾール−５−イル］−３−ニトロベンゼン−１，２−ジオールの結晶形
BRPI1014865B1 (pt) 2009-04-01 2020-03-17 Bial - Portela & C.A., S.A. Composição que compreende grânulos compreendendo 2,5- dicloro- 3- (5- (3,4- dihidróxi- 5- nitrofenil)- 1,2,4- oxadiazol- 3- il)- 4,6- dimetilpiridina 1- óxido e formulação farmacêutica
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
SI2791134T1 (sl) 2011-12-13 2020-01-31 Bial - Portela & Ca S.A. Kemična spojina, ki je uporabna kot vmesna oblika za pripravo inhibitorja katehol-o-metiltransferaze
TWI638802B (zh) 2012-05-24 2018-10-21 芬蘭商奧利安公司 兒茶酚ｏ－甲基轉移酶活性抑制化合物
RU2017120184A (ru) 2014-11-28 2018-12-28 БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. Лекарства для замедления течения болезни паркинсона
JP2021532133A (ja) 2018-07-25 2021-11-25 オリオン コーポレーション ４，５−ジヒドロキシ−２−（４−メチルベンジル）イソフタロニトリル溶媒和物およびその結晶形
EP3877360A1 (de) 2018-11-09 2021-09-15 Orion Corporation Verfahren zur herstellung von 4,5-dihydroxy-2-(4-methylbenzyl)isophthalonitril
WO2022158991A1 (en) 2021-01-20 2022-07-28 Bial-Portela & Ca., S.A. Treatment of pain associated with parkinson's disease with opicapone in combination with levodopa

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB898879A (en) 1959-10-16 1962-06-14 Smith & Nephew Hydrazine derivatives
US5236952A (en) 1986-03-11 1993-08-17 Hoffmann-La Roche Inc. Catechol derivatives
DK175069B1 (da) * 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
YU213587A (en) * 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
FI864875A0 (fi) 1986-11-28 1986-11-28 Orion Yhtymae Oy Nya farmakologiskt aktiva foereningar, dessa innehaollande kompositioner samt foerfarande och mellanprodukter foer anvaendning vid framstaellning av dessa.
US5283352A (en) 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
US5489614A (en) * 1987-11-27 1996-02-06 Orion-Yhtyma Oy Catechol derivatives, their physiologically acceptable salts, esters and use
MTP1031B (en) * 1987-12-24 1990-10-04 Orion Yhtymae Oy New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters
US5470737A (en) * 1993-06-09 1995-11-28 Mayo Foundation For Medical Education And Research Stably-transformed cells expressing human thiopurine methyltransferase
GB9510481D0 (en) * 1995-05-24 1995-07-19 Orion Yhtymae Oy New catechol derivatives
GB9626472D0 (en) 1996-12-20 1997-02-05 Aperia Anita C New use of comt inhibitors
US6169103B1 (en) * 1998-03-03 2001-01-02 Warner-Lambert Fluorine-substituted biphenyl butyric acids and their derivatives as inhibitors of matrix metalloproteinases
US6599530B2 (en) * 1998-09-14 2003-07-29 Orion Corporation Oral compacted composition comprising catechol derivatives

Also Published As

Publication number Publication date
EP1263425B1 (de) 2003-12-17
ATE256461T1 (de) 2004-01-15
CA2403352C (en) 2009-05-05
WO2001068083A1 (en) 2001-09-20
JP2003526663A (ja) 2003-09-09
US20030069316A1 (en) 2003-04-10
EP1263425A1 (de) 2002-12-11
US6723754B2 (en) 2004-04-20
CA2403352A1 (en) 2001-09-20
JP4874489B2 (ja) 2012-02-15
FI20000635A0 (fi) 2000-03-17
AU2001246600A1 (en) 2001-09-24
DE60101559T2 (de) 2004-09-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition