ES8706203A1 - Procedimiento de preparacion de eteres arilglicidilicos y de 1-alquilamino-2-propanoles 3-sustituidos o de una sal del mismo farmaceuticamente aceptable - Google Patents

Procedimiento de preparacion de eteres arilglicidilicos y de 1-alquilamino-2-propanoles 3-sustituidos o de una sal del mismo farmaceuticamente aceptable

Info

Publication number
ES8706203A1
ES8706203A1 ES551925A ES551925A ES8706203A1 ES 8706203 A1 ES8706203 A1 ES 8706203A1 ES 551925 A ES551925 A ES 551925A ES 551925 A ES551925 A ES 551925A ES 8706203 A1 ES8706203 A1 ES 8706203A1
Authority
ES
Spain
Prior art keywords
compound
optionally substituted
formula
preparation
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551925A
Other languages
English (en)
Other versions
ES551925A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Shell Internationale Research Maatschappij BV
Original Assignee
Gist Brocades NV
Shell Internationale Research Maatschappij BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858503665A external-priority patent/GB8503665D0/en
Priority claimed from GB858525456A external-priority patent/GB8525456D0/en
Application filed by Gist Brocades NV, Shell Internationale Research Maatschappij BV filed Critical Gist Brocades NV
Publication of ES551925A0 publication Critical patent/ES551925A0/es
Publication of ES8706203A1 publication Critical patent/ES8706203A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)

Abstract

METODO DE PREPARAR ETERES ARILGLICIDILICOS Y DE 1-ALQUILAMINO-2-PROPANOLES 3-SUSTITUIDOS. CONSISTE EN SOMETER UN COMPUESTO DE FORMULA (III) A LA ACCION DE UN MICROORGANISMO DOTADO DE LA CAPACIDAD DE EPOXIDACION ESTEREOSELECTIVA DEL COMPUESTO DE FORMULA (II), PARA OBTENER ETERES ARILGLICIDILICOS Y DE 1-ALQUILAMINO-2-PROPANOLES 3-SUSTITUIDOS DE FORMULAS (I) O (III), DONDE R1 ES UN GRUPO ARILO OPTATIVAMENTE SUSTITUIDO QUE INCLUYE UN GRUPO FENILO O NAFLTILO, O ES UN ANILLO HETEROAROMATICO DE 5 O 6 MIEMBROS QUE CONTIENE UNO O MAS ATOMOS DE AZUFRE, O, NI Y OTROS; Y R2 ES UN GRUPO ALQUILO DE C 2 A 6. TIENEN APLICACIONES AGRICOLAS Y FARMACEUTICAS.
ES551925A 1985-02-13 1986-02-13 Procedimiento de preparacion de eteres arilglicidilicos y de 1-alquilamino-2-propanoles 3-sustituidos o de una sal del mismo farmaceuticamente aceptable Expired ES8706203A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858503665A GB8503665D0 (en) 1985-02-13 1985-02-13 Producing arylglycidyl ether
GB858525456A GB8525456D0 (en) 1985-10-16 1985-10-16 Arylglycidyl ethers

Publications (2)

Publication Number Publication Date
ES551925A0 ES551925A0 (es) 1987-06-01
ES8706203A1 true ES8706203A1 (es) 1987-06-01

Family

ID=26288812

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551925A Expired ES8706203A1 (es) 1985-02-13 1986-02-13 Procedimiento de preparacion de eteres arilglicidilicos y de 1-alquilamino-2-propanoles 3-sustituidos o de una sal del mismo farmaceuticamente aceptable

Country Status (12)

Country Link
EP (1) EP0193227B1 (es)
CN (1) CN86102227A (es)
AU (1) AU589594B2 (es)
DE (1) DE3670289D1 (es)
DK (1) DK67786A (es)
ES (1) ES8706203A1 (es)
FI (1) FI86890C (es)
GR (1) GR860402B (es)
HU (1) HU201296B (es)
NO (1) NO166726C (es)
NZ (1) NZ215065A (es)
PT (1) PT82019B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1240942A (en) * 1984-05-28 1988-08-23 Keizo Furuhashi Process for the preparation of epoxides by means of microorganisms
GB8618324D0 (en) * 1986-07-28 1986-09-03 Shell Int Research Phenylacetate/atenolol
GB8917496D0 (en) * 1989-07-31 1989-09-13 Ici Plc Microbiological production of 2,3-epoxypropyl ethers
JPH0674243B2 (ja) * 1989-12-27 1994-09-21 ダイソー株式会社 光学純度の高い光学活性アテノロール塩及びアテノロールの製法
US5223646A (en) * 1989-12-27 1993-06-29 Daiso Company, Ltd. Process for producing optically active atenolol and intermediate thereof
SE9000207L (sv) * 1990-01-22 1991-07-23 Nobel Chemicals Ab Laekemedel samt anvaendningen av detsamma
JP2801768B2 (ja) * 1990-11-17 1998-09-21 日東電工株式会社 新規な光学活性メトプロロール・酒石酸誘導体塩及びその製法、並びにこの塩を用いる光学活性メトプロロールの製法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1458392A (en) * 1973-11-09 1976-12-15 Ici Ltd Optically-active 1-aryloxy-2,3-epoxypropane derivatives
CA1240942A (en) * 1984-05-28 1988-08-23 Keizo Furuhashi Process for the preparation of epoxides by means of microorganisms

Also Published As

Publication number Publication date
NO166726C (no) 1991-08-28
FI86890C (fi) 1992-10-26
NZ215065A (en) 1990-03-27
ES551925A0 (es) 1987-06-01
EP0193227A1 (en) 1986-09-03
FI860598A (fi) 1986-08-14
HU201296B (en) 1990-10-28
NO860507L (no) 1986-08-14
FI860598A0 (fi) 1986-02-10
FI86890B (fi) 1992-07-15
HUT40071A (en) 1986-11-28
AU589594B2 (en) 1989-10-19
DK67786A (da) 1986-08-14
PT82019B (pt) 1987-12-30
NO166726B (no) 1991-05-21
DK67786D0 (da) 1986-02-12
AU5327086A (en) 1987-04-30
GR860402B (en) 1986-06-12
DE3670289D1 (de) 1990-05-17
CN86102227A (zh) 1987-02-04
PT82019A (en) 1986-03-01
EP0193227B1 (en) 1990-04-11

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203