ES8506720A1 - Un procedimiento para la preparacion de un compuesto - Google Patents

Un procedimiento para la preparacion de un compuesto

Info

Publication number
ES8506720A1
ES8506720A1 ES533147A ES533147A ES8506720A1 ES 8506720 A1 ES8506720 A1 ES 8506720A1 ES 533147 A ES533147 A ES 533147A ES 533147 A ES533147 A ES 533147A ES 8506720 A1 ES8506720 A1 ES 8506720A1
Authority
ES
Spain
Prior art keywords
equivalent
alkoxyaminomethyl
beta
dioxide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES533147A
Other languages
English (en)
Other versions
ES533147A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES8506720A1 publication Critical patent/ES8506720A1/es
Publication of ES533147A0 publication Critical patent/ES533147A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE 1,1-DIOXIDOS DE ACIDOS PENICILANICOS, DE FORMULA GENERAL (I), EN LA QUE R5 ES UN GRUPO PROTECTOR DEL CARBOXI ELIMINABLE POR HIDROGENOLISIS O UN RADICAL FORMADOR DE ESTER; X ES HIDROGENO O BROMO; Y R ES ALQUILO C1-4 O BENCILO.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R5 Y X TIENEN LOS SIGNIFICADOS YA MENCIONADOS, CON UN EQUIVALENTE DE BROMURO O CLORURO DE METILMAGNESIO, EN UN DISOLVENTE ETEREO Y A UNA TEMPERATURA COMPRENDIDA ENTRE C50 Y C100 GRADOS; Y EN HACER REACCIONAR LA SOLUCION RESULTANTE CON UN EQUIVALENTE DE ROCNFCH2 Y CON UN EQUIVALENTE DE BF3.DE APLICACION EN MEDICINA COMO INHIBIDORES DE BBB-LACTAMASAS.
ES533147A 1983-06-06 1984-06-05 Un procedimiento para la preparacion de un compuesto Granted ES533147A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/501,475 US4499017A (en) 1983-06-06 1983-06-06 Beta-lactamase inhibiting 6-(alkoxyamino-methyl) penicillanic acid 1,1-dioxide and derivatives

Publications (2)

Publication Number Publication Date
ES8506720A1 true ES8506720A1 (es) 1985-08-01
ES533147A0 ES533147A0 (es) 1985-08-01

Family

ID=23993709

Family Applications (1)

Application Number Title Priority Date Filing Date
ES533147A Granted ES533147A0 (es) 1983-06-06 1984-06-05 Un procedimiento para la preparacion de un compuesto

Country Status (21)

Country Link
US (1) US4499017A (es)
EP (1) EP0128037B1 (es)
JP (1) JPS606693A (es)
KR (1) KR870000312B1 (es)
AT (1) ATE24512T1 (es)
AU (1) AU545467B2 (es)
CA (1) CA1247597A (es)
DE (1) DE3461800D1 (es)
DK (1) DK275884A (es)
ES (1) ES533147A0 (es)
FI (1) FI842255A (es)
GR (1) GR82214B (es)
HU (1) HU193573B (es)
IL (1) IL72003A (es)
NO (1) NO842248L (es)
NZ (1) NZ208381A (es)
PH (2) PH21372A (es)
PL (1) PL144040B1 (es)
PT (1) PT78689A (es)
YU (1) YU97084A (es)
ZA (1) ZA844184B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8928373D0 (en) * 1989-12-15 1990-02-21 Erba Carlo Spa Beta-lactam derivatives
JP4102664B2 (ja) * 2000-07-19 2008-06-18 ノバルティス アクチエンゲゼルシャフト バルサルタン塩

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
DE2927004A1 (de) * 1979-07-04 1981-05-27 Bayer Ag, 5090 Leverkusen Penicillansaeure-1,1-dioxide, ihre herstellung und ihre verwendung als arzneimittel als arzneimittel
US4287181A (en) * 1979-10-22 1981-09-01 Pfizer Inc. Derivatives of 6β-hydroxyalkylpenicillanic acids as β-lactamase inhibitors
RO87705A (ro) * 1982-01-11 1985-10-31 Pfizer Inc,Us Procedeu pentru prepararea unor derivati ai acidului 6-aminoalchilpenicilanic 1,1-dioxid

Also Published As

Publication number Publication date
CA1247597A (en) 1988-12-28
IL72003A0 (en) 1984-10-31
YU97084A (en) 1986-10-31
PL248043A1 (en) 1985-07-30
KR870000312B1 (ko) 1987-02-26
NZ208381A (en) 1987-05-29
PH22842A (en) 1989-01-19
AU2907684A (en) 1984-12-13
FI842255A (fi) 1984-12-07
KR850000446A (ko) 1985-02-27
NO842248L (no) 1984-12-07
DK275884D0 (da) 1984-06-04
EP0128037B1 (en) 1986-12-30
DE3461800D1 (en) 1987-02-05
EP0128037A1 (en) 1984-12-12
HU193573B (en) 1987-10-28
GR82214B (es) 1984-12-13
ZA844184B (en) 1986-01-29
PH21372A (en) 1987-10-15
ES533147A0 (es) 1985-08-01
PT78689A (en) 1984-07-01
JPS606693A (ja) 1985-01-14
ATE24512T1 (de) 1987-01-15
US4499017A (en) 1985-02-12
AU545467B2 (en) 1985-07-18
HUT35266A (en) 1985-06-28
DK275884A (da) 1985-01-09
PL144040B1 (en) 1988-04-30
IL72003A (en) 1988-02-29
FI842255A0 (fi) 1984-06-05

Similar Documents

Publication Publication Date Title
ES8801188A1 (es) Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos.
NO931482D0 (no) Farmasoeytiske sammensetninger inneholdende quinolin- og quinazolinderivater og nye forbindelser for disse
ES8507498A1 (es) Un procedimiento para la preparacion de acidos fenilquinolin-carboxilicos.
ATE46501T1 (de) Abkoemmlinge der guanidinomethylbenzoesaeure.
ES8403131A1 (es) Un procedimiento para la preparacion de derivados de 1,1-dioxido del acido penicilanico.
ES8506720A1 (es) Un procedimiento para la preparacion de un compuesto
DE2965701D1 (en) 1-imidazol-2-ylidene-3-thienyl-urea derivatives, processes therefor, and pharmaceutical compositions
ES2109530T3 (es) Derivados de acidos fenil-ciclohexano-carboxilicos heterotriciclicamente sustituidos.
ES8303393A1 (es) Un procedimiento para preparar derivados del acido ascorbico.
FI872997A0 (fi) Amidderivat.
FI862636A0 (fi) Farmaceutiska kompositoner med neuroleptisk effekt och foerfarande foer deras framstaellning.
GB1160064A (en) Indole Derivatives
DK363284A (da) Endo-8,8-dialkyl-8-azoniabicyclo/3.2.1/octan-6,7-exo-epoxy-3-alkylcarboxylatsalte, fremgangsmaade til fremstilling heraf og terapeutiske praeparater indeholdende disse
SE8207480L (sv) Nya bicykliska foreningar och ett forfarande for framstellning derav
ES8300747A1 (es) Procedimiento para la preparacion de derivados de acido in- dolacetico
ES8302719A1 (es) Un procedimiento para preparar compuestos de cefem
ES8604158A1 (es) Procedimiento para la obtencion de iminosulfonamidas
CA1246075A (en) AMINOALKOXYBENZOPYRANONES USED AS ANTIPSYCHOTIC AGENTS
ES8507520A1 (es) Un procedimiento para la preparacion de nuevos compuestos de b-lactama
ES8506637A1 (es) Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1, 3-dialquil-1h-pirazol-4-il-aroil-metanonas
JPS57176961A (en) Pyridonecarboxylic acid derivative
ES8401490A1 (es) Un procedimiento para la preparacion de un derivado de 3-carboxillavam.
PT71043A (en) Process for the preparation of 2,6-diaminonebularines
ATE1585T1 (de) Clavulansaeurederivate, ihre herstellung und sie enthaltende pharmazeutische praeparate.
ZA848205B (en) 2-phenoxypropionic acid derivatives of pentities of the heterocyclic ether type,processes for the manufacture of these compounds as well as herbicidal agents containing the same