ES8505345A1 - Un procedimiento para la preparacion de nuevos derivados de aminoeticpiridina o pirazina. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de aminoeticpiridina o pirazina.

Info

Publication number
ES8505345A1
ES8505345A1 ES530878A ES530878A ES8505345A1 ES 8505345 A1 ES8505345 A1 ES 8505345A1 ES 530878 A ES530878 A ES 530878A ES 530878 A ES530878 A ES 530878A ES 8505345 A1 ES8505345 A1 ES 8505345A1
Authority
ES
Spain
Prior art keywords
radical
preparation
pharmaceutical compositions
compositions containing
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530878A
Other languages
English (en)
Other versions
ES530878A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre Europeen de Recherches Mauvernay CERM
Original Assignee
Centre Europeen de Recherches Mauvernay CERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Europeen de Recherches Mauvernay CERM filed Critical Centre Europeen de Recherches Mauvernay CERM
Publication of ES8505345A1 publication Critical patent/ES8505345A1/es
Publication of ES530878A0 publication Critical patent/ES530878A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE DERIVADOS DE AMINOETIL-PIRIDINA O PIRAZINA, DE FORMULA (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, DONDE X ES -CHF O -NF; R1 Y R3 SON ALQUILO DE 1 A 5 ATOMOS DE C; Y R2 ES H; O R2 Y R3 JUNTO CON N CONSTITUYEN UN RADICAL HETEROCICLICO.MEDIANTE REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA AMINA DE FORMULA (III), SIENDO HAL HALOGENO Y LOS RESTANTES RADICALES LOS YA INDICADOS.DE APLICACION POR SUS PROPIEDADES ANTIBRONCO-CONSTRICTORAS.
ES530878A 1983-03-22 1984-03-22 Un procedimiento para la preparacion de nuevos derivados de aminoeticpiridina o pirazina. Granted ES530878A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8304690A FR2543139B1 (fr) 1983-03-22 1983-03-22 Derives de (1-alcoxy 2-amino) ethyl pyridine ou pyrazine, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
ES8505345A1 true ES8505345A1 (es) 1985-05-16
ES530878A0 ES530878A0 (es) 1985-05-16

Family

ID=9287109

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530878A Granted ES530878A0 (es) 1983-03-22 1984-03-22 Un procedimiento para la preparacion de nuevos derivados de aminoeticpiridina o pirazina.

Country Status (16)

Country Link
US (1) US4668679A (es)
EP (1) EP0120770B1 (es)
JP (1) JPS59231070A (es)
KR (1) KR840008012A (es)
AT (1) ATE33134T1 (es)
AU (1) AU560543B2 (es)
CA (1) CA1230878A (es)
DE (1) DE3470039D1 (es)
DK (1) DK163584A (es)
ES (1) ES530878A0 (es)
FI (1) FI80263C (es)
FR (1) FR2543139B1 (es)
GR (1) GR81806B (es)
HU (1) HU191600B (es)
PT (1) PT78281B (es)
ZA (1) ZA841907B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8530602D0 (en) * 1985-12-12 1986-01-22 Fujisawa Pharmaceutical Co Heterocyclic compounds
DE3615293A1 (de) * 1986-05-06 1987-11-12 Bayer Ag Verwendung von heteroarylethylaminen zur leistungsfoerderung bei tieren, heteroarylethylamine und verfahren zu ihrer herstellung
US5181105A (en) * 1986-05-30 1993-01-19 Canon Kabushiki Kaisha Color image correction based on characteristics of a highlights or other predetermined image portion
WO2007035425A2 (en) * 2005-09-16 2007-03-29 Janssen Pharmaceutica N.V. Cyclopropyl amines as modulators of the histamine h3 receptor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1385772A (fr) * 1963-01-23 1965-01-15 Ciba Geigy Procédé de préparation de composés pipéraziniques, entre autres de la 1-[2-(4-chlorophényl)-2-éthoxy-éthyl]-4-(2-méthoxy-phényl)-pipérazine
NL143925C (es) * 1965-03-09
US3952101A (en) * 1975-04-14 1976-04-20 Smithkline Corporation α-Amino methyl-5-hydroxy-2-pyridinemethanols
GB1551993A (en) * 1976-09-21 1979-09-05 Malesci Sas Pharmacologiclly active derivatives of 1 alkyl 4-phenylpiperazines and the preparation thereof
AT344180B (de) * 1976-09-29 1978-07-10 Malesci Sas Verfahren zum herstellen von neuen 1-alkyl-4-phenyl-piperazinen
FI791727A (fi) * 1978-06-05 1979-12-06 Ciba Geigy Ag Foerfarande foer framstaellning av n-alkylerade aminoalkoholer
US4358455A (en) * 1980-12-23 1982-11-09 Merck & Co., Inc. Aralkylamindethanol heterocyclic compounds
IT1200928B (it) * 1983-07-11 1989-01-27 Malesci Sas Procedimento per la preparazione di 1-piridil-alchil-4-aril piperazine utili per la loro attivita' antiipertensiva,lloro separazione nei relativi antipodi ottici e composti stereoisomeri cosi' ottenuti

Also Published As

Publication number Publication date
ZA841907B (en) 1984-10-31
ATE33134T1 (de) 1988-04-15
EP0120770A1 (fr) 1984-10-03
FI80263C (fi) 1990-05-10
FI841115A0 (fi) 1984-03-20
PT78281A (en) 1984-04-01
FI80263B (fi) 1990-01-31
JPS59231070A (ja) 1984-12-25
FI841115A (fi) 1984-09-23
DE3470039D1 (en) 1988-04-28
GR81806B (es) 1984-12-12
FR2543139B1 (fr) 1985-08-16
DK163584D0 (da) 1984-03-22
US4668679A (en) 1987-05-26
HU191600B (en) 1987-03-30
KR840008012A (ko) 1984-12-12
AU560543B2 (en) 1987-04-09
DK163584A (da) 1984-09-23
PT78281B (en) 1986-04-21
FR2543139A1 (fr) 1984-09-28
ES530878A0 (es) 1985-05-16
CA1230878A (en) 1987-12-29
EP0120770B1 (fr) 1988-03-23
AU2593984A (en) 1984-09-27

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