ES2006336A6 - Procedimiento de preparacion de nuevas acetamidas derivadas de la 2,3-dihidro-3-fenil-2-benzofuranona. - Google Patents
Procedimiento de preparacion de nuevas acetamidas derivadas de la 2,3-dihidro-3-fenil-2-benzofuranona.Info
- Publication number
- ES2006336A6 ES2006336A6 ES8800578A ES8800578A ES2006336A6 ES 2006336 A6 ES2006336 A6 ES 2006336A6 ES 8800578 A ES8800578 A ES 8800578A ES 8800578 A ES8800578 A ES 8800578A ES 2006336 A6 ES2006336 A6 ES 2006336A6
- Authority
- ES
- Spain
- Prior art keywords
- radical
- dihydro
- phenyl
- benzofuran
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE COMPUESTOS DE LA FORMULA GENERAL I, EN LA QUE R1 REPRESENTA HIDROGENO O HALOGENO, Y R2 Y R3, IGUALES O DIFERENTES, REPRESENTAN HIDROGENO, O ALQUILO INFERIOR LINEAL O RAMIFICADO, O BENCILO EVENTUALMENTE SUSTITUIDO POR HALOGENO, ALCOXILO O ALQUILO INFERIORES, 3,4-METILEDIOXIBENCILO, O BIEN, JUNTO CON EL NITROGENO AL QUE ESTAN UNIDOS, FORMAN 4-MORFOLINILO O 1-PIPERAZINILO, CARACTERIZADO PORQUE SE CONDENSA ACIDO LINILO O 1-PIPERAZINILO, CARACTERIZADO PORQUE SE CONDENSA ACIDO MANDELICO, DIRECTAMENTE CON UNA HIDROXIFENIL ACETAMIDA N,N-DISUSTITUIDA EVENTUALMENTE HALOGENADA, O BIEN CON UN DERIVADO DEL ACIDO HIDROXIFENIL ACETICO, PARA DAR UN DERIVADO ACIDO DE 2-BENZOFURANOTA, QUE POR TRATAMIENTO SUCESIVO CON CLORURO DE TIONILO Y UNA AMINA SUSTITUIDA, CONDUCE AL DESEADO DERIVADO ACETAMIDA.LOS COMPUESTOS ASI OBTENIDO POSEEN IMPORTANTES PROPIEDADES TERAPEUTICAS COMO POTENTES ANTIHIPOXICOS, MEDICAMENTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8702631A FR2611715B1 (fr) | 1987-02-27 | 1987-02-27 | Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2006336A6 true ES2006336A6 (es) | 1989-04-16 |
Family
ID=9348402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8800578A Expired ES2006336A6 (es) | 1987-02-27 | 1988-02-27 | Procedimiento de preparacion de nuevas acetamidas derivadas de la 2,3-dihidro-3-fenil-2-benzofuranona. |
Country Status (16)
Country | Link |
---|---|
US (1) | US4812469A (es) |
EP (1) | EP0281471B1 (es) |
JP (1) | JPS63227583A (es) |
AT (1) | ATE53839T1 (es) |
AU (1) | AU598346B2 (es) |
CA (1) | CA1313872C (es) |
DE (1) | DE3860117D1 (es) |
DK (1) | DK163922C (es) |
ES (1) | ES2006336A6 (es) |
FR (1) | FR2611715B1 (es) |
GR (1) | GR1000161B (es) |
IE (1) | IE61990B1 (es) |
NZ (1) | NZ223664A (es) |
OA (1) | OA08719A (es) |
PT (1) | PT86852B (es) |
ZA (1) | ZA881384B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0474589A1 (de) * | 1990-08-02 | 1992-03-11 | Ciba-Geigy Ag | Orthophenolacetamide |
WO2013019682A1 (en) * | 2011-07-29 | 2013-02-07 | Tempero Pharmaceuticals, Inc. | Compounds and methods |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB176309A (en) * | 1921-03-03 | 1922-09-21 | Mario Calderara | Improvements in or relating to the renewal of electric incandescent lamps |
US2472666A (en) * | 1946-05-16 | 1949-06-07 | Du Pont | Production of dye intermediates |
GB2044272B (en) * | 1979-02-05 | 1983-03-16 | Sandoz Ltd | Stabilising polymers |
US4618621A (en) * | 1984-09-21 | 1986-10-21 | The Upjohn Company | Method for treating medical conditions involving cerebral ischemia |
FR2593504B1 (fr) * | 1986-01-30 | 1988-12-09 | Ile De France | Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques |
-
1987
- 1987-02-27 FR FR8702631A patent/FR2611715B1/fr not_active Expired
-
1988
- 1988-02-08 CA CA000558388A patent/CA1313872C/fr not_active Expired - Fee Related
- 1988-02-12 US US07/155,353 patent/US4812469A/en not_active Expired - Fee Related
- 1988-02-26 IE IE52988A patent/IE61990B1/en not_active IP Right Cessation
- 1988-02-26 JP JP63044082A patent/JPS63227583A/ja active Granted
- 1988-02-26 AT AT88400442T patent/ATE53839T1/de not_active IP Right Cessation
- 1988-02-26 ZA ZA881384A patent/ZA881384B/xx unknown
- 1988-02-26 DK DK104488A patent/DK163922C/da not_active IP Right Cessation
- 1988-02-26 OA OA59291A patent/OA08719A/xx unknown
- 1988-02-26 GR GR880100112A patent/GR1000161B/el unknown
- 1988-02-26 AU AU12345/88A patent/AU598346B2/en not_active Ceased
- 1988-02-26 NZ NZ223664A patent/NZ223664A/xx unknown
- 1988-02-26 DE DE8888400442T patent/DE3860117D1/de not_active Expired - Lifetime
- 1988-02-26 EP EP88400442A patent/EP0281471B1/fr not_active Expired - Lifetime
- 1988-02-26 PT PT86852A patent/PT86852B/pt not_active IP Right Cessation
- 1988-02-27 ES ES8800578A patent/ES2006336A6/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
PT86852B (pt) | 1992-05-29 |
AU1234588A (en) | 1988-09-01 |
ATE53839T1 (de) | 1990-06-15 |
OA08719A (fr) | 1989-03-31 |
JPH0558634B2 (es) | 1993-08-27 |
US4812469A (en) | 1989-03-14 |
IE880529L (en) | 1988-08-27 |
DK104488A (da) | 1988-08-28 |
JPS63227583A (ja) | 1988-09-21 |
DE3860117D1 (de) | 1990-06-07 |
FR2611715B1 (fr) | 1989-05-12 |
ZA881384B (en) | 1989-05-30 |
IE61990B1 (en) | 1994-12-14 |
FR2611715A1 (fr) | 1988-09-09 |
DK163922B (da) | 1992-04-21 |
PT86852A (pt) | 1988-03-01 |
GR1000161B (el) | 1991-10-10 |
DK163922C (da) | 1992-09-21 |
GR880100112A (en) | 1988-12-16 |
DK104488D0 (da) | 1988-02-26 |
EP0281471A1 (fr) | 1988-09-07 |
EP0281471B1 (fr) | 1990-05-02 |
CA1313872C (fr) | 1993-02-23 |
NZ223664A (en) | 1989-09-27 |
AU598346B2 (en) | 1990-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19990405 |