ES543655A0 - Metodo de preparar compuestos 1,4-dihidropiridinicos - Google Patents
Metodo de preparar compuestos 1,4-dihidropiridinicosInfo
- Publication number
- ES543655A0 ES543655A0 ES543655A ES543655A ES543655A0 ES 543655 A0 ES543655 A0 ES 543655A0 ES 543655 A ES543655 A ES 543655A ES 543655 A ES543655 A ES 543655A ES 543655 A0 ES543655 A0 ES 543655A0
- Authority
- ES
- Spain
- Prior art keywords
- preparing
- dihydropyridine compounds
- dihydropyridine
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH685882 | 1982-11-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8603700A1 ES8603700A1 (es) | 1986-01-16 |
ES543655A0 true ES543655A0 (es) | 1986-01-16 |
Family
ID=4316137
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES527776A Expired ES8706633A1 (es) | 1982-11-24 | 1983-11-24 | Procedimiento de preparacion de derivados de 1,4-dihidropiridinas. |
ES543652A Expired ES8604147A1 (es) | 1982-11-24 | 1985-05-30 | Procedimiento de obtencion de derivados 1,4-dihidropiridini-cos |
ES543655A Expired ES8603700A1 (es) | 1982-11-24 | 1985-05-30 | Metodo de preparar compuestos 1,4-dihidropiridinicos |
ES543654A Expired ES8603699A1 (es) | 1982-11-24 | 1985-05-30 | Metodo de obtener derivados de 1,4-dihidropiridinas |
ES543653A Expired ES8703139A1 (es) | 1982-11-24 | 1985-05-30 | Procedimiento de preparar derivados de 1,4-dihidropiridinas |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES527776A Expired ES8706633A1 (es) | 1982-11-24 | 1983-11-24 | Procedimiento de preparacion de derivados de 1,4-dihidropiridinas. |
ES543652A Expired ES8604147A1 (es) | 1982-11-24 | 1985-05-30 | Procedimiento de obtencion de derivados 1,4-dihidropiridini-cos |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES543654A Expired ES8603699A1 (es) | 1982-11-24 | 1985-05-30 | Metodo de obtener derivados de 1,4-dihidropiridinas |
ES543653A Expired ES8703139A1 (es) | 1982-11-24 | 1985-05-30 | Procedimiento de preparar derivados de 1,4-dihidropiridinas |
Country Status (8)
Country | Link |
---|---|
US (2) | US4656181A (es) |
EP (1) | EP0126094B1 (es) |
JP (1) | JPS60500255A (es) |
CA (1) | CA1256872A (es) |
DE (1) | DE3381680D1 (es) |
ES (5) | ES8706633A1 (es) |
IT (1) | IT1167269B (es) |
WO (1) | WO1984002132A1 (es) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4603135A (en) * | 1983-10-17 | 1986-07-29 | Takeda Chemical Industries, Ltd. | Substituted piperazinyl alkyl esters of 2-amino-4-aryl-1,4-dihydro-6-alkyl-3,5-pyridinedicarboxylates |
US5137889A (en) * | 1983-12-02 | 1992-08-11 | Otsuka Pharmaceutical Co., Ltd. | Dihydropyridine derivatives and process for preparing the same |
JPS60120861A (ja) * | 1983-12-02 | 1985-06-28 | Otsuka Pharmaceut Co Ltd | ジヒドロピリジン誘導体 |
IE57810B1 (en) * | 1984-03-27 | 1993-04-21 | Delagrange Lab | 1,4-dihydropyridine derivatives,their preparation and their use |
GB2162513B (en) * | 1984-06-25 | 1988-01-20 | Toyama Chemical Co Ltd | Dihydropyridine derivatives |
JPS6147477A (ja) * | 1984-08-14 | 1986-03-07 | Kowa Co | 新規1,4−ジヒドロピリジン−3,5−ジカルボン酸エステル誘導体 |
IL76366A (en) * | 1984-09-14 | 1989-07-31 | Ciba Geigy Ag | 2,6-dialkyl-4-aryl-3,5-diacyl-1,4-dihydropyridine derivatives,processes for their manufacture and pharmaceutical preparations containing them |
US4975440A (en) * | 1984-09-28 | 1990-12-04 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Optically-active 1,4-dihydropyridine |
GB8428552D0 (en) * | 1984-11-12 | 1984-12-19 | Sandoz Ltd | Organic compounds |
JPH0676405B2 (ja) * | 1986-06-13 | 1994-09-28 | 日清製粉株式会社 | 1,4―ジヒドロピリジン誘導体およびそれを含有する医薬組成物 |
US4757071A (en) * | 1984-12-14 | 1988-07-12 | Nisshin Flour Milling Co., Ltd. | 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases |
IL77843A (en) * | 1985-02-11 | 1989-07-31 | Syntex Inc | Dihydropyridine derivatives,process and novel intermediates for their preparation and pharmaceutical compositions containing them |
JPS61227567A (ja) * | 1985-04-01 | 1986-10-09 | Eisai Co Ltd | 1,4−ジヒドロピリジン誘導体 |
EP0222702A3 (de) * | 1985-11-06 | 1988-01-07 | Ciba-Geigy Ag | Basische Carbonylverbindungen |
DE3600594A1 (de) * | 1986-01-11 | 1987-07-16 | Bayer Ag | Methioninsubstituierte 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung |
DE3601397A1 (de) * | 1986-01-18 | 1987-07-23 | Bayer Ag | Substituierte 1,4-dihydropyridin-3-carbonsaeurepiperazide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
DK114587A (da) * | 1986-03-12 | 1987-09-13 | Byk Gulden Lomberg Chem Fab | Monocycliske esterderivater |
DE3617976A1 (de) * | 1986-05-28 | 1988-01-14 | Alter Sa | 1,4-dihydropyridin, verfahren zu dessen herstellung und dessen verwendung in antithrombotischen medikamenten |
US4761420A (en) * | 1986-06-13 | 1988-08-02 | Laboratoires Syntex S.A. | Antihypertensive dihydropyridine derivatives |
US4886819A (en) * | 1986-08-27 | 1989-12-12 | The Green Cross Corporation | Dihydropyridine derivatives and pharmaceutical composition thereof |
JPH0688973B2 (ja) * | 1987-03-12 | 1994-11-09 | 京都薬品工業株式会社 | 1,4−ジヒドロピリジン誘導体 |
US5047543A (en) * | 1988-11-24 | 1991-09-10 | Taisho Pharmaceutical Co., Ltd. | 1,4-dihydropyridine derivatives |
US5635395A (en) * | 1992-08-31 | 1997-06-03 | Mercian Corporation | Optically active 1,4-dihydropyridine compounds and the microbial process for the stereoselection thereof |
DE4233347A1 (de) * | 1992-10-05 | 1994-04-07 | Bayer Ag | Dihydropyridin-alkoxy- und -alkylamino-aroylester |
DE4236707A1 (de) * | 1992-10-30 | 1994-05-05 | Bayer Ag | 4-Heterocyclyl substituierte Dihydropyridine |
ES2096179T3 (es) * | 1992-10-30 | 1997-03-01 | Bayer Ag | Dihidropiridinas sustituidas en la posicion 4 con un heterociclilfenilo. |
US6001857A (en) * | 1992-10-30 | 1999-12-14 | Bayer Aktiengesellschaft | Heterocyclyl substituted dihydropyridines |
DE4342193A1 (de) * | 1993-12-10 | 1995-06-14 | Bayer Ag | Arylsubstituierte Alkoxycarbonyl-1,4-dihydropyridin-5-carbonsäureester |
WO1996006829A1 (fr) * | 1994-08-29 | 1996-03-07 | Mercian Corporation | Derive de 1,4-dihydropyrydine |
EP1146860A4 (en) * | 1999-01-08 | 2002-07-03 | Emisphere Tech Inc | POLYMER DRUG DELIVERY SYSTEMS AND COMPOUNDS |
CN100450483C (zh) * | 2000-04-11 | 2009-01-14 | 三共株式会社 | 含有钙阻滞剂的稳定药物组合物 |
TW200736245A (en) * | 2005-11-29 | 2007-10-01 | Sankyo Co | Acid addition salts of optically active dihydropyridine derivatives |
TW200806648A (en) * | 2005-11-29 | 2008-02-01 | Sankyo Co | Acid addition salts of dihydropyridine derivatives |
US9227978B2 (en) | 2013-03-15 | 2016-01-05 | Araxes Pharma Llc | Covalent inhibitors of Kras G12C |
TW201524952A (zh) * | 2013-03-15 | 2015-07-01 | Araxes Pharma Llc | Kras g12c之共價抑制劑 |
TWI659021B (zh) | 2013-10-10 | 2019-05-11 | 亞瑞克西斯製藥公司 | Kras g12c之抑制劑 |
CN105669532B (zh) * | 2014-12-03 | 2018-11-02 | 广州市恒诺康医药科技有限公司 | 尼莫地平水溶性衍生物及其制备方法和应用 |
EP3280708B1 (en) | 2015-04-10 | 2021-09-01 | Araxes Pharma LLC | Substituted quinazoline compounds and methods of use thereof |
MX2017013275A (es) | 2015-04-15 | 2018-01-26 | Araxes Pharma Llc | Inhibidores triciclicos fusionados de kras y metodos de uso de los mismos. |
US10144724B2 (en) | 2015-07-22 | 2018-12-04 | Araxes Pharma Llc | Substituted quinazoline compounds and methods of use thereof |
WO2017058915A1 (en) | 2015-09-28 | 2017-04-06 | Araxes Pharma Llc | Inhibitors of kras g12c mutant proteins |
EP3356359B1 (en) | 2015-09-28 | 2021-10-20 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
WO2017058805A1 (en) | 2015-09-28 | 2017-04-06 | Araxes Pharma Llc | Inhibitors of kras g12c mutant proteins |
WO2017058902A1 (en) | 2015-09-28 | 2017-04-06 | Araxes Pharma Llc | Inhibitors of kras g12c mutant proteins |
US10858343B2 (en) | 2015-09-28 | 2020-12-08 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
WO2017058768A1 (en) | 2015-09-28 | 2017-04-06 | Araxes Pharma Llc | Inhibitors of kras g12c mutant proteins |
US10875842B2 (en) | 2015-09-28 | 2020-12-29 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
CA3005089A1 (en) | 2015-11-16 | 2017-05-26 | Araxes Pharma Llc | 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof |
US10646488B2 (en) | 2016-07-13 | 2020-05-12 | Araxes Pharma Llc | Conjugates of cereblon binding compounds and G12C mutant KRAS, HRAS or NRAS protein modulating compounds and methods of use thereof |
WO2018064510A1 (en) | 2016-09-29 | 2018-04-05 | Araxes Pharma Llc | Inhibitors of kras g12c mutant proteins |
US10377743B2 (en) | 2016-10-07 | 2019-08-13 | Araxes Pharma Llc | Inhibitors of RAS and methods of use thereof |
EP3573970A1 (en) | 2017-01-26 | 2019-12-04 | Araxes Pharma LLC | 1-(6-(3-hydroxynaphthalen-1-yl)quinazolin-2-yl)azetidin-1-yl)prop-2-en-1-one derivatives and similar compounds as kras g12c inhibitors for the treatment of cancer |
US11274093B2 (en) | 2017-01-26 | 2022-03-15 | Araxes Pharma Llc | Fused bicyclic benzoheteroaromatic compounds and methods of use thereof |
US11279689B2 (en) | 2017-01-26 | 2022-03-22 | Araxes Pharma Llc | 1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1 yl)prop-2-en-1-one derivatives and similar compounds as KRAS G12C modulators for treating cancer |
US11358959B2 (en) | 2017-01-26 | 2022-06-14 | Araxes Pharma Llc | Benzothiophene and benzothiazole compounds and methods of use thereof |
EP3573967A1 (en) | 2017-01-26 | 2019-12-04 | Araxes Pharma LLC | Fused hetero-hetero bicyclic compounds and methods of use thereof |
JP2020521741A (ja) | 2017-05-25 | 2020-07-27 | アラクセス ファーマ エルエルシー | がんの処置のための化合物およびその使用の方法 |
BR112019024674A2 (pt) | 2017-05-25 | 2020-06-16 | Araxes Pharma Llc | Inibidores covalentes da kras |
US11639346B2 (en) | 2017-05-25 | 2023-05-02 | Araxes Pharma Llc | Quinazoline derivatives as modulators of mutant KRAS, HRAS or NRAS |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670824C3 (de) * | 1967-03-20 | 1978-08-03 | Bayer Ag, 5090 Leverkusen | 1,4-Dihydropyridin-33-dicarbonsäurealkylester |
DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
DE2117573C3 (de) * | 1971-04-10 | 1978-07-27 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel |
DE2218644C3 (de) * | 1972-04-18 | 1982-08-19 | Bayer Ag, 5090 Leverkusen | Basische Ester von 1,4-Dihydropyridinen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
US3996234A (en) * | 1972-04-18 | 1976-12-07 | Bayer Aktiengesellschaft | 1,4-Dihydropyridine carboxylic acid esters |
DE2508181A1 (de) * | 1975-02-26 | 1976-09-09 | Bayer Ag | 1,4-dihydropyridincarbonsaeurearal- kylester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
FR2405937A1 (fr) * | 1977-10-14 | 1979-05-11 | Labaz | Nouveaux derives de dihydropyridine, leur procede de preparation et leur application |
SE429652B (sv) * | 1978-06-30 | 1983-09-19 | Haessle Ab | 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester |
DE2847236A1 (de) * | 1978-10-31 | 1980-05-14 | Bayer Ag | Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
US4258042A (en) * | 1980-04-11 | 1981-03-24 | Usv Pharmaceutical Corporation | Antihypertensive pyridines and compositions |
DE3042769A1 (de) * | 1980-11-13 | 1982-06-09 | Bayer Ag, 5090 Leverkusen | C-3 verknuepfte 1,4-dihydropyridine, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung |
NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
DE3208628A1 (de) * | 1982-03-10 | 1983-09-22 | Bayer Ag, 5090 Leverkusen | Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
WO1983003249A1 (en) * | 1982-03-17 | 1983-09-29 | Yoshitomi Pharmaceutical | 1,4-dihydropyridine-3,5-dicarboxylate derivatives |
-
1982
- 1982-11-18 US US06/637,216 patent/US4656181A/en not_active Expired - Lifetime
-
1983
- 1983-11-18 EP EP83903371A patent/EP0126094B1/fr not_active Expired - Lifetime
- 1983-11-18 JP JP58503515A patent/JPS60500255A/ja active Granted
- 1983-11-18 WO PCT/CH1983/000128 patent/WO1984002132A1/de active IP Right Grant
- 1983-11-18 DE DE8383903371T patent/DE3381680D1/de not_active Expired - Lifetime
- 1983-11-23 IT IT23841/83A patent/IT1167269B/it active
- 1983-11-23 CA CA000441800A patent/CA1256872A/fr not_active Expired
- 1983-11-24 ES ES527776A patent/ES8706633A1/es not_active Expired
-
1985
- 1985-05-30 ES ES543652A patent/ES8604147A1/es not_active Expired
- 1985-05-30 ES ES543655A patent/ES8603700A1/es not_active Expired
- 1985-05-30 ES ES543654A patent/ES8603699A1/es not_active Expired
- 1985-05-30 ES ES543653A patent/ES8703139A1/es not_active Expired
-
1986
- 1986-06-30 US US06/880,148 patent/US4727066A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH0559906B2 (es) | 1993-09-01 |
US4656181A (en) | 1987-04-07 |
CA1256872A (fr) | 1989-07-04 |
ES8603700A1 (es) | 1986-01-16 |
ES8703139A1 (es) | 1987-02-16 |
EP0126094A1 (fr) | 1984-11-28 |
ES8604147A1 (es) | 1986-01-16 |
ES543653A0 (es) | 1987-02-16 |
IT8323841A0 (it) | 1983-11-23 |
ES8603699A1 (es) | 1986-01-16 |
ES543654A0 (es) | 1986-01-16 |
ES543652A0 (es) | 1986-01-16 |
WO1984002132A1 (en) | 1984-06-07 |
EP0126094B1 (fr) | 1990-06-20 |
ES527776A0 (es) | 1987-07-16 |
DE3381680D1 (de) | 1990-07-26 |
ES8706633A1 (es) | 1987-07-16 |
IT1167269B (it) | 1987-05-13 |
JPS60500255A (ja) | 1985-02-28 |
US4727066A (en) | 1988-02-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES543655A0 (es) | Metodo de preparar compuestos 1,4-dihidropiridinicos | |
ES516523A0 (es) | "metodo de preparar compuestos benzoheterociclicos". | |
KR840005446A (ko) | N--4-피페리딘아민의 제조방법 | |
ES520637A0 (es) | Metodo de preparar compuestos carbostirilicos. | |
DK302086A (da) | Fremgangsmaade til fremstilling af 1 alfa-hydroxyvitamin-d-forbindelser | |
PL252773A1 (en) | Method of obtaining novel derivatives of 1,4-dihydropyridine | |
IT1203706B (it) | Metodo per la preparazione di 26,26,26,27,27,27-esafluoro-1-alfa,25-diidrossicolesterolo | |
DK379985A (da) | Fremgangsmaade til fremstilling af 6-chlor-n-methyl-2,3,4,5-tetrahydro-lh-benzazepin | |
IT1189393B (it) | Composti di 1,4-diidropiridina | |
KR850004570A (ko) | 2,2-디플루오로프로피온산 유도체의 제조방법 | |
KR860004922A (ko) | N-포르밀-α-아스파르틸페닐알라닌의 제조방법 | |
DK160489C (da) | Fremgangsmaade til fremstilling af 2,3-difluorpyridinforbindelser | |
ES538157A0 (es) | Procedimiento para preparar derivados de 1,4-dihidropiridina | |
ES547411A0 (es) | Procedimiento de preparar compuestos triaminobencenicos yo- dados | |
DK24083D0 (da) | Fremgangsmade til fremstilling af 0,0'-dithiodibenzoesyrer | |
DK154207C (da) | Fremgangsmaade til fremstilling af 1,8-dihydroxy-10-acyl-9-anthroner | |
KR860700031A (ko) | 살충제 화합물의 제조방법 | |
KR860005812A (ko) | 4,4-디알킬-2-아제티디논의 제조 방법 | |
RO92377A (ro) | Procedeu pentru prepararea 8-halo-5,6-dialcoxichinazoli-2,4-dionelor | |
DK454183A (da) | Fremgangsmaade til fremstilling af 15-cycloaliphatiske derivater af 13,14-didehydro-carboprostancycliner | |
KR860004941A (ko) | 아실-락탐화합물을 제조하는 방법 | |
KR860004939A (ko) | N-치환된 아실-락탐 화합물을 제조하는 방법 | |
KR840004092A (ko) | N-치환-테트라하이드로티아진의 제조방법 | |
KR860004940A (ko) | N-치환된 아실-락탐 화합물을 제조하는 방법 | |
ES530247A0 (es) | Un metodo para preparar compuestos de 1, 4-dihidropiridina |