ES461388A1 - Un procedimiento para la preparacion de un compuesto de pi- rrolidona. - Google Patents
Un procedimiento para la preparacion de un compuesto de pi- rrolidona.Info
- Publication number
- ES461388A1 ES461388A1 ES461388A ES461388A ES461388A1 ES 461388 A1 ES461388 A1 ES 461388A1 ES 461388 A ES461388 A ES 461388A ES 461388 A ES461388 A ES 461388A ES 461388 A1 ES461388 A1 ES 461388A1
- Authority
- ES
- Spain
- Prior art keywords
- phenyl
- alkyl
- carbon atoms
- tetrazol
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un procedimiento para la preparación de un compuesto de pirrolidona de la fórmula: **(Fórmula)** y el epímero de C5 del mismo, donde: Q es -COOR'', tetrazol-5-ilo o -CONHR"; W es un enlace sencillo o un enlace doble con configuración cis; Z es un enlace sencillo o un enlace doble de configuración trans; M es H/"''OH ó HO/"''H; R es alfa-tienilo, fenilo, fenoxi monosusituído o fenoxi monosustituido, en que el sustituyente es cloro, flúor, fenilo, metoxi trifluometilo o alquilo que tiene de uno a tres átomos de carbono; R'' es hidrógeno, alquilo que tiene de uno a cinco átomos de carbono, fenilo o p-bifenilo; R" es -COR''" o -SO2R''" , en que R"'' es fenilo o alquilo que tiene de uno a cinco átomos de carbono; y las sales de metal alcalino, metal alcalinotérreo y amonio de aquellos compuestos en que Q es un grupo carboxilato o tetrazol-5-ilo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71236276A | 1976-08-06 | 1976-08-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES461388A1 true ES461388A1 (es) | 1978-12-01 |
Family
ID=24861795
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES461388A Expired ES461388A1 (es) | 1976-08-06 | 1977-08-05 | Un procedimiento para la preparacion de un compuesto de pi- rrolidona. |
ES471349A Expired ES471349A1 (es) | 1976-08-06 | 1978-07-01 | Un procedimiento para la preparacion de un compuesto de pi- rrolidona |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES471349A Expired ES471349A1 (es) | 1976-08-06 | 1978-07-01 | Un procedimiento para la preparacion de un compuesto de pi- rrolidona |
Country Status (31)
Country | Link |
---|---|
JP (2) | JPS5321159A (es) |
AR (1) | AR217080A1 (es) |
AT (1) | AT362887B (es) |
AU (1) | AU508007B2 (es) |
BE (1) | BE857506A (es) |
BG (1) | BG31073A3 (es) |
CA (1) | CA1077948A (es) |
CH (1) | CH624934A5 (es) |
CS (1) | CS221269B2 (es) |
DD (2) | DD143768A5 (es) |
DE (1) | DE2735904A1 (es) |
DK (1) | DK352077A (es) |
ES (2) | ES461388A1 (es) |
FI (1) | FI70009C (es) |
FR (1) | FR2369260A1 (es) |
GB (2) | GB1556570A (es) |
GR (1) | GR68688B (es) |
HU (1) | HU180273B (es) |
IE (1) | IE45505B1 (es) |
IL (1) | IL52615A (es) |
LU (1) | LU77936A1 (es) |
NL (1) | NL7708637A (es) |
NO (1) | NO772752L (es) |
NZ (1) | NZ184806A (es) |
PH (1) | PH17398A (es) |
PL (2) | PL112931B1 (es) |
PT (1) | PT66891B (es) |
SE (1) | SE423813B (es) |
SU (3) | SU703016A3 (es) |
YU (1) | YU192577A (es) |
ZA (1) | ZA774704B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5695569A (en) * | 1979-12-27 | 1981-08-03 | Canon Inc | Forming method for bar lens sphere face |
US4321201A (en) * | 1980-09-22 | 1982-03-23 | E. I. Du Pont De Nemours And Company | Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl) heptanoates |
JPS59137224A (ja) * | 1983-01-25 | 1984-08-07 | Mitsubishi Electric Corp | 電気鉄道用き電電圧補償装置 |
IL141120A0 (en) | 2000-01-31 | 2002-02-10 | Pfizer Prod Inc | Use of prostaglandin (pge2) receptor 4 (epa) selective agonists for the treatment of acute and chronic renal failure |
AU2001290250A1 (en) * | 2000-09-21 | 2002-04-02 | Ono Pharmaceutical Co. Ltd. | Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient |
CZ20031257A3 (cs) * | 2000-11-27 | 2004-04-14 | Pfizer Products Inc. | Selektivní agonisty receptoru EP4 při léčení osteoporosy |
PT1417975E (pt) * | 2001-07-23 | 2011-05-30 | Ono Pharmaceutical Co | Medicamentos que cont?m um agonista de ep4 como princ?pio activo destinados a doen?as associadas a perda de massa ?ssea |
EP1487437B1 (en) * | 2002-03-18 | 2006-08-16 | Pfizer Products Inc. | Use of selective ep4 receptor agonists for the treatment of diseases |
US6573294B1 (en) * | 2002-05-14 | 2003-06-03 | Allergan, Inc. | 8-azaprostaglandin analogs as agents for lowering intraocular pressure |
US7256211B1 (en) * | 2003-01-21 | 2007-08-14 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivatives and medical use thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1386146A (en) * | 1972-05-03 | 1975-03-05 | Ici Ltd | Cyclopentane derivatives |
JPS511460A (en) * | 1974-06-24 | 1976-01-08 | Tanabe Seiyaku Co | 22 piroridonjudotaino seiho |
JPS514166A (ja) * | 1974-06-28 | 1976-01-14 | Tanabe Seiyaku Co | 22piroridonjudotaino seiho |
US3975399A (en) * | 1974-08-06 | 1976-08-17 | E. I. Du Pont De Nemours And Company | 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones |
DE2528664A1 (de) * | 1975-06-27 | 1977-01-13 | Hoechst Ag | Pyrrolidone und verfahren zu ihrer herstellung |
-
1977
- 1977-07-27 SE SE7708642A patent/SE423813B/xx unknown
- 1977-07-27 CA CA283,598A patent/CA1077948A/en not_active Expired
- 1977-07-28 GR GR54058A patent/GR68688B/el unknown
- 1977-07-28 IL IL52615A patent/IL52615A/xx unknown
- 1977-08-01 AU AU27515/77A patent/AU508007B2/en not_active Expired
- 1977-08-02 NZ NZ184806A patent/NZ184806A/xx unknown
- 1977-08-02 PH PH20060A patent/PH17398A/en unknown
- 1977-08-04 PT PT66891A patent/PT66891B/pt unknown
- 1977-08-04 NL NL7708637A patent/NL7708637A/xx not_active Application Discontinuation
- 1977-08-04 ZA ZA00774704A patent/ZA774704B/xx unknown
- 1977-08-05 ES ES461388A patent/ES461388A1/es not_active Expired
- 1977-08-05 CS CS775202A patent/CS221269B2/cs unknown
- 1977-08-05 NO NO772752A patent/NO772752L/no unknown
- 1977-08-05 GB GB43588/78A patent/GB1556570A/en not_active Expired
- 1977-08-05 FI FI772376A patent/FI70009C/fi not_active IP Right Cessation
- 1977-08-05 DD DD77213369A patent/DD143768A5/de unknown
- 1977-08-05 LU LU77936A patent/LU77936A1/xx unknown
- 1977-08-05 AR AR268699A patent/AR217080A1/es active
- 1977-08-05 HU HU77PI587A patent/HU180273B/hu unknown
- 1977-08-05 SU SU772511155A patent/SU703016A3/ru active
- 1977-08-05 YU YU01925/77A patent/YU192577A/xx unknown
- 1977-08-05 GB GB33002/77A patent/GB1556569A/en not_active Expired
- 1977-08-05 IE IE1641/77A patent/IE45505B1/en unknown
- 1977-08-05 DK DK352077A patent/DK352077A/da not_active Application Discontinuation
- 1977-08-05 BG BG7737109A patent/BG31073A3/xx unknown
- 1977-08-05 FR FR7724290A patent/FR2369260A1/fr active Granted
- 1977-08-05 DE DE19772735904 patent/DE2735904A1/de not_active Ceased
- 1977-08-05 DD DD77200468A patent/DD136135A5/xx unknown
- 1977-08-05 CH CH964677A patent/CH624934A5/fr not_active IP Right Cessation
- 1977-08-05 BE BE1008318A patent/BE857506A/xx not_active IP Right Cessation
- 1977-08-06 JP JP9458977A patent/JPS5321159A/ja active Granted
- 1977-08-08 PL PL1977215666A patent/PL112931B1/pl unknown
- 1977-08-08 AT AT0579477A patent/AT362887B/de not_active IP Right Cessation
- 1977-08-08 PL PL77200124A patent/PL200124A1/xx unknown
-
1978
- 1978-07-01 ES ES471349A patent/ES471349A1/es not_active Expired
- 1978-10-11 SU SU782672200A patent/SU818480A3/ru active
- 1978-10-17 SU SU782674602A patent/SU850000A3/ru active
-
1979
- 1979-09-03 JP JP54112743A patent/JPS585196B2/ja not_active Expired
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19981103 |