ES460040A1 - Un procedimiento para preparar derivados de 4-hidroxifeni- lalcanolaminas. - Google Patents

Un procedimiento para preparar derivados de 4-hidroxifeni- lalcanolaminas.

Info

Publication number
ES460040A1
ES460040A1 ES460040A ES460040A ES460040A1 ES 460040 A1 ES460040 A1 ES 460040A1 ES 460040 A ES460040 A ES 460040A ES 460040 A ES460040 A ES 460040A ES 460040 A1 ES460040 A1 ES 460040A1
Authority
ES
Spain
Prior art keywords
hydroxyphenylalkanolamine
derivatives
preparation
compounds
substituents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES460040A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of ES460040A1 publication Critical patent/ES460040A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un procedimiento para preparar derivados de 4-hidroxifenilalcanolamina que en la forma de base libre tienen la fórmula I, en donde R1, R2, R3 son independientemente hidrógeno o alquilo inferior; n es un número entero de 1 a 3; Ar es fenilo o fenilo que tiene de 1 a 3 sustituyentes de halógeno, alquilo inferior, hidroxi o alcoxi inferior; Q es alquiltio inferior, alquilsulfinilo inferior o alquilsulfonilo inferior; e Y es hidrógeno, alcanoilo inferior, Troilo, becenosulfonilo o toluensulfonilo;
ES460040A 1976-06-25 1977-06-23 Un procedimiento para preparar derivados de 4-hidroxifeni- lalcanolaminas. Expired ES460040A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69985676A 1976-06-25 1976-06-25
US80337277A 1977-06-03 1977-06-03

Publications (1)

Publication Number Publication Date
ES460040A1 true ES460040A1 (es) 1978-05-01

Family

ID=27106508

Family Applications (1)

Application Number Title Priority Date Filing Date
ES460040A Expired ES460040A1 (es) 1976-06-25 1977-06-23 Un procedimiento para preparar derivados de 4-hidroxifeni- lalcanolaminas.

Country Status (21)

Country Link
JP (1) JPS5321134A (es)
AR (2) AR220896A1 (es)
AT (1) AT354420B (es)
AU (1) AU512626B2 (es)
CA (1) CA1091245A (es)
CH (2) CH627447A5 (es)
DE (1) DE2728641A1 (es)
DK (1) DK146386C (es)
ES (1) ES460040A1 (es)
FI (1) FI771976A (es)
FR (1) FR2366272A1 (es)
GB (1) GB1544872A (es)
HK (1) HK60184A (es)
IE (1) IE45631B1 (es)
IL (1) IL52353A (es)
LU (1) LU77604A1 (es)
NL (1) NL7707128A (es)
NO (1) NO144848C (es)
PH (2) PH15041A (es)
PT (1) PT66713B (es)
SE (1) SE7707341L (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4410548A (en) 1980-07-09 1983-10-18 Reckitt & Colman Products Limited Propanolamine derivatives
DE3128117A1 (de) * 1980-07-29 1982-03-11 Yamanouchi Pharmaceutical Co., Ltd., Tokyo Neue phenyl-aethylaminderivate, verfahren zu ihrer herstellung
AU620573B2 (en) * 1987-11-27 1992-02-20 Societe Nationale Elf Aquitaine Process for phenol alkylthiolation and its application to the synthesis of 4-acyl-2-alkylthiophenols
FR2623804B1 (fr) * 1987-11-27 1990-03-23 Elf Aquitaine Acylation des phenols
US5101065A (en) * 1991-02-04 1992-03-31 Imperial Chemical Industries Plc Acetophenone intermediates
DE69228410T2 (de) 1991-08-21 1999-07-08 Smith & Nephew Inc Flüssigkeitenbehandlungssystem
CA2319131A1 (en) 1998-01-26 1999-07-29 Walter H. Moos Mitochondria protecting agents for treating mitochondria associated diseases
EP1138666B1 (en) * 2000-03-28 2004-03-03 Council of Scientific and Industrial Research A preparation method for 4-(P-methoxyphenyl)-2-amino-butane and an insecticidal composition comprising it
AU2003250483A1 (en) 2002-08-19 2004-03-11 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
CN102428061B (zh) * 2009-05-19 2015-09-30 本州化学工业株式会社 三苯酚类及其单酯取代物的制造方法及4-酰基芳烷基苯酚衍生物
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CN104324977A (zh) * 2014-10-22 2015-02-04 无锡市得力手机械有限公司 一种倒立式拉丝机的卸线车
HU231124B1 (hu) * 2016-02-10 2020-12-28 Egis Gyógyszergyár Zrt. Eljárás morfológiailag egységes mirabegron és mirabegron monohidroklorid előállítására
JOP20210193A1 (ar) 2019-01-18 2023-01-30 Astrazeneca Ab مثبطات pcsk9 وطرق استخدامها

Also Published As

Publication number Publication date
CH627447A5 (en) 1982-01-15
PT66713B (en) 1978-11-21
CA1091245A (en) 1980-12-09
AR227126A1 (es) 1982-09-30
CH630068A5 (en) 1982-05-28
LU77604A1 (es) 1978-02-01
FR2366272B1 (es) 1981-03-06
NL7707128A (nl) 1977-12-28
AT354420B (de) 1979-01-10
GB1544872A (en) 1979-04-25
IE45631B1 (en) 1982-10-20
DK146386B (da) 1983-09-26
PT66713A (en) 1977-07-01
IL52353A (en) 1981-07-31
PH14332A (en) 1981-05-29
FR2366272A1 (fr) 1978-04-28
AU2636877A (en) 1979-01-04
SE7707341L (sv) 1978-02-13
AU512626B2 (en) 1980-10-23
NO144848C (no) 1981-11-25
ATA449377A (de) 1979-06-15
FI771976A (es) 1977-12-26
PH15041A (en) 1982-05-20
DK281777A (da) 1977-12-26
HK60184A (en) 1984-08-10
AR220896A1 (es) 1980-12-15
DK146386C (da) 1984-03-12
DE2728641A1 (de) 1978-01-05
NO772245L (no) 1977-12-28
JPS5321134A (en) 1978-02-27
IL52353A0 (en) 1977-08-31
IE45631L (en) 1977-12-25
NO144848B (no) 1981-08-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971103