ES431263A1 - Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos. - Google Patents
Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos.Info
- Publication number
- ES431263A1 ES431263A1 ES431263A ES431263A ES431263A1 ES 431263 A1 ES431263 A1 ES 431263A1 ES 431263 A ES431263 A ES 431263A ES 431263 A ES431263 A ES 431263A ES 431263 A1 ES431263 A1 ES 431263A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- carbon atoms
- alcohol
- alkoxy
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR157273X | 1935-11-15 | ||
DE19722210620 DE2210620C2 (de) | 1972-03-06 | 1972-03-06 | Bis-Phenoxypropanolamine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
DE19722260620 DE2260620A1 (de) | 1972-12-11 | 1972-12-11 | Messerturbomuehle |
DE19722260444 DE2260444A1 (de) | 1972-12-11 | 1972-12-11 | Neue bis-alkanol-aminderivate, deren saeureadditionssalze, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ES431263A1 true ES431263A1 (es) | 1977-02-01 |
Family
ID=27431439
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES412333A Expired ES412333A1 (es) | 1935-11-15 | 1973-03-05 | Procedimiento para la preparacion de nuevos n,n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)- alfa, omega - iamino-alcanos recemicos u opticamente activos. |
ES431264A Expired ES431264A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxisustituido-2-hidroxi-1-propil)-alfa, omega-diaminoal- canos racemicos u opticamente activos. |
ES431263A Expired ES431263A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos. |
ES431266A Expired ES431266A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)-alfa,omega-diaminoal- canos racemicos u opticamente activos. |
ES431265A Expired ES431265A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)-alfa,omega-diaminoal- canos racemicos u opticamente activos. |
ES431261A Expired ES431261A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos. |
ES431262A Expired ES431262A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES412333A Expired ES412333A1 (es) | 1935-11-15 | 1973-03-05 | Procedimiento para la preparacion de nuevos n,n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)- alfa, omega - iamino-alcanos recemicos u opticamente activos. |
ES431264A Expired ES431264A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxisustituido-2-hidroxi-1-propil)-alfa, omega-diaminoal- canos racemicos u opticamente activos. |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES431266A Expired ES431266A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)-alfa,omega-diaminoal- canos racemicos u opticamente activos. |
ES431265A Expired ES431265A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)-alfa,omega-diaminoal- canos racemicos u opticamente activos. |
ES431261A Expired ES431261A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos. |
ES431262A Expired ES431262A1 (es) | 1935-11-15 | 1974-10-23 | Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos. |
Country Status (12)
Country | Link |
---|---|
US (1) | US3888898A (es) |
JP (1) | JPS5825657B2 (es) |
AT (5) | AT325023B (es) |
CH (7) | CH601182A5 (es) |
DK (1) | DK141660C (es) |
ES (7) | ES412333A1 (es) |
FI (1) | FI59391C (es) |
FR (1) | FR2175055B1 (es) |
GB (1) | GB1431341A (es) |
NL (1) | NL7303097A (es) |
NO (1) | NO137049C (es) |
SE (1) | SE413402B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3975539A (en) * | 1935-11-15 | 1976-08-17 | Boehringer Ingelheim Gmbh | Pharmaceutical compositions containing an N,N-bis-(3-phenoxy-2-hydroxy-propyl)-alkylenediamine and method of use |
US4024281A (en) * | 1972-05-26 | 1977-05-17 | Smithkline Corporation | N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines |
US4041074A (en) * | 1973-07-19 | 1977-08-09 | Imperial Chemical Industries Limited | 1-Hydroxyaryl-2-amidoalkylaminoethanol derivatives |
US4029783A (en) * | 1973-08-03 | 1977-06-14 | Boehringer Mannheim G.M.B.H. | N-substituted 1-amino-3-phenoxy-propan-2-ol compounds and therapeutic compositions containing them |
FI65987C (fi) * | 1973-12-12 | 1984-08-10 | Ici Ltd | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat |
US4041075A (en) * | 1973-12-12 | 1977-08-09 | Imperial Chemical Industries Limited | Phenoxy-alkanolamine derivatives |
US4139623A (en) * | 1974-05-14 | 1979-02-13 | C-G Corp. | Cyclic-substituted derivatives of 1-amino-2-propanol |
DE2555920C2 (de) * | 1974-12-24 | 1983-12-15 | Rohm and Haas Co., 19105 Philadelphia, Pa. | Mehrzweckzusatz für Benzin und eine ihn enthaltende Kraftstoffmischung |
US4013777A (en) * | 1975-08-22 | 1977-03-22 | Smithkline Corporation | Bis-phenoxypropanolamines |
FR2330383A1 (fr) * | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
IE47053B1 (en) * | 1977-05-23 | 1983-12-14 | Ici Ltd | Cardiac stimulants |
US4163053A (en) * | 1977-12-27 | 1979-07-31 | Schering Corporation | Anti-hypertensive 5-[2-(substituted anilinoalkylamino)-1-hydroxyalkyl]salicylamides |
US4351848A (en) * | 1978-03-16 | 1982-09-28 | Drug Science Foundation | 1-((1-Methylethyl)amino)-3-(((4-alkylthio)1-naphthalenyl)oxy)-2-propanol |
DE3068678D1 (en) * | 1979-08-10 | 1984-08-30 | Sandoz Ag | 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them |
US4342783A (en) * | 1980-06-30 | 1982-08-03 | Synthelabo | Anti-glaucoma agent |
US4945182A (en) * | 1985-12-24 | 1990-07-31 | Merck & Co., Inc. | Oculoselective beta-blockers |
US4751278A (en) * | 1987-04-29 | 1988-06-14 | Ciba-Geigy Corporation | Adducts of monoepoxides and selected diamines |
US6001824A (en) * | 1988-02-08 | 1999-12-14 | The Trustees Of Columbia University | Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same |
WO1989007098A1 (en) * | 1988-02-08 | 1989-08-10 | The Trustees Of Columbia University In The City Of | Butyrl-tyrosinyl spermine, analogs thereof and methods of preparing and using same |
JP3356289B2 (ja) * | 1995-06-26 | 2002-12-16 | コンキャット リミティド | 第一遷移系列元素に対してキレート化親和性および選択性のある化合物とその医療および診断への使用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3459782A (en) * | 1963-08-26 | 1969-08-05 | Boehringer Sohn Ingelheim | 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes |
US3541130A (en) * | 1967-02-06 | 1970-11-17 | Boehringer Sohn Ingelheim | 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes |
DE1901549B2 (de) * | 1968-09-30 | 1978-04-13 | Veb Fahlberg-List, Chemische Und Pharmazeutische Fabriken, Ddr 3011 Magdeburg | N,N'-Bis-[3-(2'-äthoxyphenoxy)-2-hydroxypropyl] -ethylendiamin, Verfahren zu dessen Herstellung und Arzneimittel auf dessen Basis |
BE754604A (fr) * | 1969-08-08 | 1971-02-08 | Boehringer Sohn Ingelheim | Le 1-(2-nitrilophenoxy)-2-hydroxy-3-ethyl-aminopropane et ses sels |
-
1973
- 1973-02-22 AT AT132074A patent/AT325023B/de not_active IP Right Cessation
- 1973-02-22 AT AT131774A patent/AT323132B/de not_active IP Right Cessation
- 1973-02-22 AT AT157273A patent/AT326107B/de not_active IP Right Cessation
- 1973-02-22 AT AT131674A patent/AT323131B/de not_active IP Right Cessation
- 1973-02-22 AT AT131874A patent/AT325022B/de not_active IP Right Cessation
- 1973-02-27 US US336269A patent/US3888898A/en not_active Expired - Lifetime
- 1973-03-01 CH CH302173A patent/CH601182A5/xx not_active IP Right Cessation
- 1973-03-01 CH CH614676A patent/CH599924A5/xx not_active IP Right Cessation
- 1973-03-01 CH CH614876A patent/CH605633A5/xx not_active IP Right Cessation
- 1973-03-01 CH CH614776A patent/CH605630A5/xx not_active IP Right Cessation
- 1973-03-01 CH CH614976A patent/CH605634A5/xx not_active IP Right Cessation
- 1973-03-01 CH CH615076A patent/CH605631A5/xx not_active IP Right Cessation
- 1973-03-05 DK DK117273A patent/DK141660C/da not_active IP Right Cessation
- 1973-03-05 SE SE7303063A patent/SE413402B/xx unknown
- 1973-03-05 ES ES412333A patent/ES412333A1/es not_active Expired
- 1973-03-05 JP JP48025943A patent/JPS5825657B2/ja not_active Expired
- 1973-03-05 NO NO878/73A patent/NO137049C/no unknown
- 1973-03-05 FI FI667/73A patent/FI59391C/fi active
- 1973-03-06 NL NL7303097A patent/NL7303097A/xx not_active Application Discontinuation
- 1973-03-06 FR FR7307886A patent/FR2175055B1/fr not_active Expired
- 1973-03-06 GB GB1089673A patent/GB1431341A/en not_active Expired
-
1974
- 1974-10-23 ES ES431264A patent/ES431264A1/es not_active Expired
- 1974-10-23 ES ES431263A patent/ES431263A1/es not_active Expired
- 1974-10-23 ES ES431266A patent/ES431266A1/es not_active Expired
- 1974-10-23 ES ES431265A patent/ES431265A1/es not_active Expired
- 1974-10-23 ES ES431261A patent/ES431261A1/es not_active Expired
- 1974-10-23 ES ES431262A patent/ES431262A1/es not_active Expired
-
1976
- 1976-05-17 CH CH615176A patent/CH605632A5/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US3888898A (en) | 1975-06-10 |
FI59391C (fi) | 1981-08-10 |
ATA157273A (de) | 1975-02-15 |
CH601182A5 (es) | 1978-06-30 |
NL7303097A (es) | 1973-09-10 |
DK141660C (da) | 1980-10-20 |
AT323131B (de) | 1975-06-25 |
AU5294473A (en) | 1974-09-12 |
JPS48103532A (es) | 1973-12-25 |
ES412333A1 (es) | 1976-01-01 |
CH599924A5 (es) | 1978-06-15 |
NO137049C (no) | 1977-12-21 |
CH605634A5 (es) | 1978-10-13 |
CH605630A5 (es) | 1978-10-13 |
AT325022B (de) | 1975-09-25 |
DK141660B (da) | 1980-05-19 |
CH605632A5 (es) | 1978-10-13 |
AT325023B (de) | 1975-09-25 |
ES431262A1 (es) | 1977-02-01 |
SE413402B (sv) | 1980-05-27 |
ES431261A1 (es) | 1977-02-01 |
AT326107B (de) | 1975-11-25 |
FI59391B (fi) | 1981-04-30 |
NO137049B (no) | 1977-09-12 |
GB1431341A (en) | 1976-04-07 |
ES431265A1 (es) | 1976-10-16 |
CH605633A5 (es) | 1978-10-13 |
FR2175055A1 (es) | 1973-10-19 |
AT323132B (de) | 1975-06-25 |
CH605631A5 (es) | 1978-10-13 |
FR2175055B1 (es) | 1976-08-13 |
ES431266A1 (es) | 1976-10-16 |
JPS5825657B2 (ja) | 1983-05-28 |
ES431264A1 (es) | 1976-10-16 |
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