ES430457A1 - Preparation of 2-alkoxy-5-sulphamoylbenzoic acids - Google Patents

Preparation of 2-alkoxy-5-sulphamoylbenzoic acids

Info

Publication number
ES430457A1
ES430457A1 ES430457A ES430457A ES430457A1 ES 430457 A1 ES430457 A1 ES 430457A1 ES 430457 A ES430457 A ES 430457A ES 430457 A ES430457 A ES 430457A ES 430457 A1 ES430457 A1 ES 430457A1
Authority
ES
Spain
Prior art keywords
alkoxybenzaldehyde
sulfamoyl
substituted
molecular weight
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES430457A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Original Assignee
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes Scientifiques et Industrielles de lIle de France SA filed Critical Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Publication of ES430457A1 publication Critical patent/ES430457A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A process for the preparation of sulfamoyl-substituted 2-alkoxybenzoic acids in the 5-position, corresponding to the following general formula: **(See formula)** in which: A is a low molecular weight (1 to 5 carbon atoms) alcohol or alkenyl radical; B is a low molecular weight amino, monoalkoxylamino or dialcoylamino radical in which the alcohol groups can be linked together to form a ring with or without nitrogen, oxygen or sulfur; when the ring contains a nitrogen atom, said nitrogen atom can be attached to a low molecular weight alcohol group, an example of the resulting rings being: pyrrolidinyl, piperidinyl, imidazolidinyl, piperazine, morpholino or diazolidinyl, characterized in that said process comprises Starting from the salicylic aldehyde, treat it with an alcoholizing agent to produce a 2-alkoxybenzaldehyde on which ethyl orthoformate is reacted, so that the 2-alkoxybenzaldehyde diethylacetal is produced; this acetal, when treated with chlorosulfonic acid gives the corresponding 2-alkoxy-5-chlorosulfonylbenzaldehyde, which by treatment with ammonia or an amine gives the sulfamoyl-substituted 2-alkoxybenzaldehyde in the desired 5-position, which is oxidized then by an oxidizing agent to give the sulfamoyl-substituted 2-alkoxy-benzoic acid in the corresponding 5-position. (Machine-translation by Google Translate, not legally binding)
ES430457A 1973-10-02 1974-09-27 Preparation of 2-alkoxy-5-sulphamoylbenzoic acids Expired ES430457A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7335277A FR2245630B1 (en) 1973-10-02 1973-10-02

Publications (1)

Publication Number Publication Date
ES430457A1 true ES430457A1 (en) 1976-10-16

Family

ID=9125844

Family Applications (1)

Application Number Title Priority Date Filing Date
ES430457A Expired ES430457A1 (en) 1973-10-02 1974-09-27 Preparation of 2-alkoxy-5-sulphamoylbenzoic acids

Country Status (9)

Country Link
JP (1) JPS5850985B2 (en)
AR (1) AR202319A1 (en)
CA (1) CA1032552A (en)
DE (1) DE2444720A1 (en)
ES (1) ES430457A1 (en)
FI (1) FI60556C (en)
FR (1) FR2245630B1 (en)
GB (2) GB1474039A (en)
IE (1) IE39922B1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2933979A1 (en) * 1979-08-22 1981-03-12 Bayer Ag, 5090 Leverkusen NEW 4-FLUOR-3-PHENOXY-BENZALDEHYDACETALS AND METHOD FOR THEIR PRODUCTION AND NEW INTERMEDIATE PRODUCTS FOR THIS AND METHOD FOR THEIR PRODUCTION.
US4453004A (en) * 1982-04-01 1984-06-05 International Telephone And Telegraph Corporation Process for the alkylation of phenolic compounds
US6730786B2 (en) 2000-06-22 2004-05-04 Pfizer Inc Process for the preparation of pyrazolopyrimidinones

Also Published As

Publication number Publication date
FI60556C (en) 1982-02-10
FI280974A (en) 1975-04-03
GB1474039A (en) 1977-05-18
JPS5850985B2 (en) 1983-11-14
GB1474040A (en) 1977-05-18
IE39922B1 (en) 1979-01-31
FR2245630A1 (en) 1975-04-25
AR202319A1 (en) 1975-05-30
FI60556B (en) 1981-10-30
IE39922L (en) 1975-04-02
JPS5062948A (en) 1975-05-29
FR2245630B1 (en) 1977-03-11
DE2444720A1 (en) 1975-04-10
CA1032552A (en) 1978-06-06

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