ES2651013T3 - Implante - Google Patents
Implante Download PDFInfo
- Publication number
- ES2651013T3 ES2651013T3 ES11787580.7T ES11787580T ES2651013T3 ES 2651013 T3 ES2651013 T3 ES 2651013T3 ES 11787580 T ES11787580 T ES 11787580T ES 2651013 T3 ES2651013 T3 ES 2651013T3
- Authority
- ES
- Spain
- Prior art keywords
- implant
- magnesium
- sintering
- sintered
- based alloy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
- A61B17/8085—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates with pliable or malleable elements or having a mesh-like structure, e.g. small strips
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/047—Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
- B22F1/06—Metallic powder characterised by the shape of the particles
- B22F1/062—Fibrous particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F9/00—Making metallic powder or suspensions thereof
- B22F9/02—Making metallic powder or suspensions thereof using physical processes
- B22F9/06—Making metallic powder or suspensions thereof using physical processes starting from liquid material
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C49/00—Alloys containing metallic or non-metallic fibres or filaments
- C22C49/14—Alloys containing metallic or non-metallic fibres or filaments characterised by the fibres or filaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00526—Methods of manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2002/3092—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth having an open-celled or open-pored structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30968—Sintering
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
- A61F2310/00035—Other metals or alloys
- A61F2310/00041—Magnesium or Mg-based alloys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Surgery (AREA)
- Cardiology (AREA)
- Inorganic Chemistry (AREA)
- Medical Informatics (AREA)
- Mechanical Engineering (AREA)
- Materials Engineering (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Metallurgy (AREA)
- Dispersion Chemistry (AREA)
- Nanotechnology (AREA)
- Materials For Medical Uses (AREA)
- Powder Metallurgy (AREA)
Abstract
Implante que se compone de magnesio o de una aleación a base de magnesio, que se caracteriza porque se compone de fibras de magnesio o de una aleación a base de magnesio las cuales están unidas entre sí por medio de puentes sinterizados, espaciados unos de otros localmente, y forman un cuerpo de poros abiertos.
Description
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Ejemplo 7:
Las fibras fabricadas de manera análoga al ejemplo 6 fueron vertidas y sinterizadas de manera análoga al ejemplo 1 para obtener una estructura de alta porosidad. Tomando en cuenta el diagrama de fase terciaría y los cálculos termodinámicos para la estimación de las temperaturas de sinterización con la ayuda del software PANDAT, la temperatura de sinterización para la aleación MgY2,6Ca1,6 se encuentra en el intervalo de 550 °C a 590 °C, lo cual corresponde a una fracción de fase líquida de 10 a 20 %.
Una sinterización de las fibras de MgY2,6Ca1,6, vertida sobre un sustrato inerte hecho de chapa de tantalio, fue realizada a 580 °C. La sinterización se efectuó tal como se describe en el ejemplo 1 en un horno de gas protector (tubo de vidrio de cuarzo) bajo argón 6.0 de alta pureza calentando la muestra a 10 K/ min hasta 550 °C, un tiempo de espera de 1 min, y calentamiento subsiguiente a 3 K/ min hasta la temperatura de sinterización Tmax de 580 °C, tiempo de espera 20 min.
La estructura sinterizada se caracteriza por contactos de sinterización estables, alta pureza de 61 % en el material de prueba y muy buena capacidad de maquinarse. El maquinado para obtener cuerpos moldeados definidos en forma de círculos con un diámetro de 10 mm fue hecho con la ayuda de cortes con láser. La estructura sinterizada se caracteriza por un alto grado de pureza (contenido de oxígeno máximo de 0,001 %). Debido a la composición modificada (2,6 % de Y; 1,6 % de Ca) la velocidad de degradación que puede medirse en la prueba de corrosión es un poco más grande que en el caso con el implante fabricado de acuerdo con el ejemplo 1.
Los implantes fabricados de acuerdo con los ejemplos 1 a 7 pueden limpiarse tal como sigue y luego también pueden recubrirse. Para propósitos de limpieza se mezclan 20 ml de glicerina (85 %), 5 ml de ácido nítrico (65 %), 5 ml de ácido acético (100 %) y el implante sinterizado se sumerge en la solución durante 30 segundos. A continuación se limpia dos veces durante 60 segundos cada vez en etanol al 100 % en un baño de ultrasonido y finalmente es soplado con un limpiador de gas comprimido. Después tiene lugar un procedimiento de secado completo en la cabina de vacío a una temperatura de 50 °C por un período de aproximadamente 10 minutos.
El implante limpiado y secado de esta manera puede sumergirse en una solución saturada de fluoruro de sodio. A la solución se agregan 4 g en 100 ml de Aqua ad iniectabilia (agua para inyección) (Braun, botella de vidrio de 100 ml) y la mezcla se pone en un contenedor de vidrio y allí se agita por un lapso de tiempo entre 1 hora y 2 hora.
Adicionando NaOH, el valor de pH se ajusta a 11,5. El implante puede colocarse en la solución obtenida de esta manera y sobre su superficie puede formarse una capa de fluoruro de sodio. Después de secarse en una cabina de vacío, la capa de fluoruro de sodio puede tener un grosor de capa medio de al menos 0,1 µm. Mediante el recubrimiento puede lograrse una disminución significativa en la tasa de corrosión, en comparación con una estructura de fibras no recubierta.
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Claims (1)
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imagen1
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/DE2011/001539 WO2013013648A1 (de) | 2011-07-27 | 2011-07-27 | Implantat |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2651013T3 true ES2651013T3 (es) | 2018-01-23 |
Family
ID=45023453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES11787580.7T Active ES2651013T3 (es) | 2011-07-27 | 2011-07-27 | Implante |
Country Status (6)
Country | Link |
---|---|
US (1) | US10709816B2 (es) |
EP (1) | EP2736431B1 (es) |
JP (1) | JP5846591B2 (es) |
KR (1) | KR101901638B1 (es) |
ES (1) | ES2651013T3 (es) |
WO (1) | WO2013013648A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5846591B2 (ja) | 2011-07-27 | 2016-01-20 | フラウンホッファー−ゲゼルシャフト・ツァー・フォデラング・デル・アンゲワンテン・フォーシュング・エー.ファウ. | インプラント |
EP2899266B1 (en) * | 2014-01-24 | 2018-03-07 | Fresenius Medical Care Deutschland GmbH | Improved differentiation of mesenchymal stem cells into osteoblasts |
DE112014007192T5 (de) * | 2014-12-25 | 2017-08-24 | Olympus Corporation | Osteosynthetisches Implantat und Herstellungsverfahren hierfür |
WO2018187407A1 (en) * | 2017-04-04 | 2018-10-11 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Mg alloy mesh reinforced polymer/ecm hybrid scaffolds for critical-sized bone defect regeneration |
WO2022098062A1 (ko) | 2020-11-04 | 2022-05-12 | 한국재료연구원 | 고강도 고내식 생분해성 마그네슘 합금 및 이를 이용하는 임플란트 |
DE102021203391A1 (de) * | 2021-04-06 | 2022-10-06 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein | Verfahren zur Herstellung von offenporösen Knochenimplantaten aus Fasern, mit frei zugänglichen Leitstrukturen aus Fasern, die aus einem biokompatiblen Metall oder Metalllegierung gebildet sind |
US20220354486A1 (en) | 2021-05-10 | 2022-11-10 | Cilag Gmbh International | System of surgical staple cartridges comprising absorbable staples |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
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DE1000097B (de) | 1953-03-30 | 1957-01-03 | Licentia Gmbh | Verwendung von Trockengleichrichter-anordnungen zum Stabilisieren einer Gleichspannung |
DE19712625C2 (de) | 1997-03-26 | 2003-02-20 | Fraunhofer Ges Forschung | Verfahren und Vorrichtung zur Herstellung eines Faserformkörpers |
US6240616B1 (en) * | 1997-04-15 | 2001-06-05 | Advanced Cardiovascular Systems, Inc. | Method of manufacturing a medicated porous metal prosthesis |
US6365092B1 (en) * | 1999-06-23 | 2002-04-02 | Abb Lummus Global, Inc. | Method for producing a sintered porous body |
US6395168B1 (en) * | 1999-11-19 | 2002-05-28 | Terra Group, Corp. | Reticulated liquid treatment device |
FR2825378B1 (fr) * | 2001-05-31 | 2003-11-28 | Univ Paris Curie | Composition et procede pour le traitement d'alliages de magnesium |
DE10163106A1 (de) | 2001-12-24 | 2003-07-10 | Univ Hannover | Medizinische Implantate, Prothesen, Protheseteile, medizinische Instrumente, Geräte und Hilfsmittel aus einem halogenid-modifizierten Magnesiumwerkstoff |
US20050163821A1 (en) * | 2002-08-02 | 2005-07-28 | Hsing-Wen Sung | Drug-eluting Biodegradable Stent and Delivery Means |
DE10241572B4 (de) | 2002-09-07 | 2007-02-08 | Werner Scholz | Stütz- oder Halteteil zum Einbringen in ein Knochenteil |
DE102005003188A1 (de) * | 2005-01-20 | 2006-07-27 | Restate Patent Ag | Medizinisches Implantat aus einer amorphen oder nanokristallinen Legierung |
MX2008000131A (es) * | 2005-07-01 | 2008-04-04 | Cinv Ag | Dispositivos medicos que comprenden un material compuesto reticulado. |
DE102006005510B4 (de) | 2006-02-01 | 2009-06-18 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vorrichtung und Verfahren zur Herstellung metallischer Fasern durch Schmelzextraktion |
US8048150B2 (en) * | 2006-04-12 | 2011-11-01 | Boston Scientific Scimed, Inc. | Endoprosthesis having a fiber meshwork disposed thereon |
BRPI0710355A2 (pt) | 2006-04-28 | 2011-08-09 | Biomagnesium Systems Ltd | ligas de magnésio biodegrádavel e usos da mesma |
JP2010503494A (ja) * | 2006-09-15 | 2010-02-04 | ボストン サイエンティフィック リミテッド | 生分解性内部人工器官およびその製造方法 |
WO2008122594A2 (en) * | 2007-04-05 | 2008-10-16 | Cinvention Ag | Partially biodegradable therapeutic implant for bone and cartilage repair |
DE102008037204B4 (de) | 2008-08-11 | 2016-01-07 | Alfred Buck | Platte zur Fixierung von Knochenfragmenten sowie Verfahren zu deren Herstellung |
DE102008046197B8 (de) | 2008-09-05 | 2010-05-20 | Verein zur Förderung von Innovationen durch Forschung, Entwicklung und Technologietransfer e.V. (Verein INNOVENT e.V.) | Degradierbares Implantat und Verfahren zu seiner Herstellung sowie deren Verwendung |
US20110082564A1 (en) * | 2009-10-07 | 2011-04-07 | Bio2 Technologies, Inc | Devices and Methods for Tissue Engineering |
EP2582407B1 (de) * | 2010-06-15 | 2014-08-27 | InnoTERE GmbH | Knochenimplantat, enthaltend einen magnesiumhaltigen metallischen werkstoff mit verminderter korrosionsrate und verfahren und set zu dessen herstellung |
WO2012003502A2 (en) * | 2010-07-02 | 2012-01-05 | University Of Florida Research Foundation, Inc. | Bioresorbable metal alloy and implants made of same |
JP5846591B2 (ja) | 2011-07-27 | 2016-01-20 | フラウンホッファー−ゲゼルシャフト・ツァー・フォデラング・デル・アンゲワンテン・フォーシュング・エー.ファウ. | インプラント |
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2011
- 2011-07-27 JP JP2014521948A patent/JP5846591B2/ja active Active
- 2011-07-27 WO PCT/DE2011/001539 patent/WO2013013648A1/de active Application Filing
- 2011-07-27 KR KR1020147005003A patent/KR101901638B1/ko active IP Right Grant
- 2011-07-27 US US14/234,681 patent/US10709816B2/en active Active
- 2011-07-27 ES ES11787580.7T patent/ES2651013T3/es active Active
- 2011-07-27 EP EP11787580.7A patent/EP2736431B1/de active Active
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Publication number | Publication date |
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EP2736431B1 (de) | 2017-09-06 |
KR101901638B1 (ko) | 2018-09-27 |
EP2736431A1 (de) | 2014-06-04 |
US10709816B2 (en) | 2020-07-14 |
KR20140078611A (ko) | 2014-06-25 |
JP2014528740A (ja) | 2014-10-30 |
JP5846591B2 (ja) | 2016-01-20 |
US20140324188A1 (en) | 2014-10-30 |
WO2013013648A1 (de) | 2013-01-31 |
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