ES2584512T3 - Imágenes oculares para el diagnóstico de enfermedades neurodegenerativas - Google Patents

Imágenes oculares para el diagnóstico de enfermedades neurodegenerativas Download PDF

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Publication number
ES2584512T3
ES2584512T3 ES09723695.4T ES09723695T ES2584512T3 ES 2584512 T3 ES2584512 T3 ES 2584512T3 ES 09723695 T ES09723695 T ES 09723695T ES 2584512 T3 ES2584512 T3 ES 2584512T3
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Spain
Prior art keywords
eye
quasi
scanning
iqls
ifls
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Inventor
Paul Hartung
Vincent Valvo
Dennis J. Nilan
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Cognoptix Inc
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Cognoptix Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/117—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/113—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining or recording eye movement

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Human Computer Interaction (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

Sistema (10) para realizar una dispersión cuasielástica de la luz y una exploración de ligandos fluorescentes en el ojo (26) de un sujeto, comprendiendo dicho sistema (10): una pantalla de visualización (88) que muestra una imagen (50) del ojo (26) para permitir que un operador seleccione lugares del ojo (26) a medir; y una unidad óptica (11) acoplada a un procesador (82) para ejecutar una dispersión cuasielástica de la luz y una exploración de ligandos fluorescentes en lugares seleccionados del ojo (26) y para adquirir datos asociados a la dispersión cuasielástica de la luz y la exploración de ligandos fluorescentes realizadas, mostrando el procesador (82) los datos en la pantalla de visualización (88) para que sean revisados por el operador, incluyendo los datos adquiridos la densidad media de la luz dispersada asociada a la dispersión cuasielástica de la luz realizada y la intensidad de fluorescencia media asociada a la exploración de ligandos fluorescentes realizada; comprendiendo el sistema además medios para determinar una relación (FLSNorm) entre la intensidad de fluorescencia media (IFLS-N) asociada a la exploración de ligandos fluorescentes de un lugar en la región del núcleo (60) del cristalino del ojo (26) y la intensidad de fluorescencia media (IFLS-SN) asociada a la exploración de ligandos fluorescentes de un lugar de la región del supranúcleo (58) del cristalino del ojo (26) de acuerdo con la ecuación FLSNorm >= IFLS-SN/IFLS-N, y medios para determinar la relación (QLSNorm) entre la intensidad media (IQLS-N) de la luz dispersada asociada a la dispersión cuasielástica de la luz en un lugar de la región del núcleo (60) del cristalino del ojo y la intensidad media (IQLS-SN) de la luz dispersada asociada a la dispersión cuasielástica de la luz en un lugar de la región del supranúcleo (58) del cristalino del ojo (26) de acuerdo con la ecuación QLSNorm >= IQLS-SN/IQLS-N, indicando un aumento de FLSNorm o QLSNorm un aumento de la presencia de un material u objeto en el ojo (26).

Description

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Claims (1)

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ES09723695.4T 2008-03-27 2009-03-27 Imágenes oculares para el diagnóstico de enfermedades neurodegenerativas Active ES2584512T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7219908P 2008-03-27 2008-03-27
US72199P 2008-03-27
PCT/US2009/001885 WO2009120349A1 (en) 2008-03-27 2009-03-27 Ocular imaging

Publications (1)

Publication Number Publication Date
ES2584512T3 true ES2584512T3 (es) 2016-09-28

Family

ID=40718786

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09723695.4T Active ES2584512T3 (es) 2008-03-27 2009-03-27 Imágenes oculares para el diagnóstico de enfermedades neurodegenerativas

Country Status (19)

Country Link
US (1) US8955969B2 (es)
EP (1) EP2268193B1 (es)
JP (1) JP2011515189A (es)
KR (1) KR101603184B1 (es)
CN (1) CN102006819B (es)
AU (1) AU2009229348B2 (es)
BR (1) BRPI0909519B8 (es)
CA (1) CA2718938C (es)
DK (1) DK2268193T3 (es)
ES (1) ES2584512T3 (es)
HK (1) HK1145958A1 (es)
HU (1) HUE028034T2 (es)
MX (1) MX2010010402A (es)
NZ (1) NZ588811A (es)
PL (1) PL2268193T3 (es)
PT (1) PT2268193T (es)
RU (1) RU2503399C2 (es)
SG (1) SG188900A1 (es)
WO (1) WO2009120349A1 (es)

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Also Published As

Publication number Publication date
KR101603184B1 (ko) 2016-03-14
WO2009120349A1 (en) 2009-10-01
US20110116041A1 (en) 2011-05-19
US8955969B2 (en) 2015-02-17
EP2268193A1 (en) 2011-01-05
DK2268193T3 (en) 2016-07-04
BRPI0909519A2 (pt) 2016-10-11
RU2503399C2 (ru) 2014-01-10
AU2009229348B2 (en) 2013-09-19
BRPI0909519B1 (pt) 2020-03-10
SG188900A1 (en) 2013-04-30
CN102006819B (zh) 2014-03-26
AU2009229348A1 (en) 2009-10-01
CA2718938C (en) 2016-11-29
NZ588811A (en) 2013-08-30
JP2011515189A (ja) 2011-05-19
MX2010010402A (es) 2010-12-17
HUE028034T2 (en) 2016-11-28
RU2010143673A (ru) 2012-05-10
BRPI0909519B8 (pt) 2021-06-22
PT2268193T (pt) 2016-07-08
EP2268193B1 (en) 2016-03-23
PL2268193T3 (pl) 2017-07-31
KR20110014573A (ko) 2011-02-11
CA2718938A1 (en) 2009-10-01
HK1145958A1 (zh) 2011-05-13
CN102006819A (zh) 2011-04-06

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