ES2188890T3 - Derivados del acido quinoleincarboxilico y sus sales. - Google Patents
Derivados del acido quinoleincarboxilico y sus sales.Info
- Publication number
- ES2188890T3 ES2188890T3 ES97902618T ES97902618T ES2188890T3 ES 2188890 T3 ES2188890 T3 ES 2188890T3 ES 97902618 T ES97902618 T ES 97902618T ES 97902618 T ES97902618 T ES 97902618T ES 2188890 T3 ES2188890 T3 ES 2188890T3
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- salts
- halogen
- acid
- quinoleincarboxilico
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Indole Compounds (AREA)
Abstract
DERIVADOS DEL ACIDO QUINOLEINCARBOXILICO REPRESENTADOS POR LA FORMULA GENERAL (I) O SALES DE ESTOS. SE PREFIEREN LOS COMPUESTOS, EN LOS QUE R 2 REPRESENTA CICLOALQUILO OPCIONALM ENTE SUSTITUIDO, R 3 REPRESENTA AL MENOS UN MIEMBRO SELECCIONADO ENTRE HIDROGENO, HALOGENO, ALQUILO O ALCOXI INFERIOR OPCIONALMENTE SUSTITUIDO E HIDROXI O AMINO OPCIONALMENTE PROTEGIDO, R 4 REPRESENTA HIDROGENO O ALQUILO INFERIOR OPCIONAL MENTE SUSTITUIDO, R 5 Y R 6 REPRESENTA CADA UNO DE ELLOS HIDROGENO Y A REPRESENTA C-Y (DONDE Y REPRESENTA HALOGENO, ALQUILO O ALCOXI INFERIOR, CADA UNO DE ELLOS OPCIONALMENTE SUSTITUIDO CON HALOGENO O HIDROXI OPCIONALMENTE PROTEGIDO).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4793696 | 1996-02-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2188890T3 true ES2188890T3 (es) | 2003-07-01 |
Family
ID=12789268
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97902618T Expired - Lifetime ES2188890T3 (es) | 1996-02-09 | 1997-02-07 | Derivados del acido quinoleincarboxilico y sus sales. |
Country Status (18)
Country | Link |
---|---|
US (1) | US6025370A (es) |
EP (1) | EP0882725B1 (es) |
KR (1) | KR100276477B1 (es) |
CN (2) | CN100395244C (es) |
AT (1) | ATE229950T1 (es) |
AU (1) | AU711914B2 (es) |
CA (1) | CA2242242C (es) |
DE (1) | DE69717970T2 (es) |
DK (1) | DK0882725T3 (es) |
ES (1) | ES2188890T3 (es) |
HK (1) | HK1039118B (es) |
HU (1) | HU228567B1 (es) |
IL (1) | IL124944A (es) |
NO (1) | NO316666B1 (es) |
NZ (1) | NZ330775A (es) |
PT (1) | PT882725E (es) |
WO (1) | WO1997029102A1 (es) |
ZA (1) | ZA971023B (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL339408A1 (en) | 1997-09-15 | 2000-12-18 | Procter & Gamble | Antimicrobial quinolones, agents containing them and their applications |
US6387928B1 (en) | 1997-09-15 | 2002-05-14 | The Procter & Gamble Co. | Antimicrobial quinolones, their compositions and uses |
CN1296369C (zh) * | 1997-10-27 | 2007-01-24 | 富山化学工业株式会社 | 制备7-二氢异吲哚喹诺酮羧酸衍生物及其中间体的方法 |
KR100550078B1 (ko) * | 1998-04-06 | 2006-02-08 | 토야마 케미칼 컴퍼니 리미티드 | 퀴놀론카본산 유도체 또는 그 염 |
JP4499846B2 (ja) * | 1998-05-07 | 2010-07-07 | 富山化学工業株式会社 | 7−イソインドリン−キノロンカルボン酸誘導体の製造法並びにイソインドリン−5−ボロン酸誘導体の製造法 |
JP4549461B2 (ja) * | 1998-08-31 | 2010-09-22 | 富山化学工業株式会社 | 7−ブロモ−キノロンカルボン酸誘導体の製造法 |
JP2000229946A (ja) * | 1998-12-10 | 2000-08-22 | Toyama Chem Co Ltd | キノロンカルボン酸の製造法およびその中間体 |
WO2000054811A1 (fr) | 1999-03-17 | 2000-09-21 | Daiichi Pharmaceutical Co., Ltd. | Compositions medicamenteuses |
CN100337630C (zh) | 2002-03-12 | 2007-09-19 | 布里斯托尔-迈尔斯斯奎布公司 | 可口的口服悬浮液及其制备方法 |
JP4616770B2 (ja) | 2003-06-19 | 2011-01-19 | 第一三共株式会社 | 選択的なアミノ置換基導入法 |
KR100981351B1 (ko) * | 2003-10-29 | 2010-09-10 | 주식회사 엘지생명과학 | 7-클로로-1-사이클로프로필-6-플루오로-4-옥소-1,4-디하이드로-1,8-나프티리딘-3-카복실산의 제조방법 |
US20090156577A1 (en) * | 2004-09-09 | 2009-06-18 | Benjamin Davis | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
WO2006093189A1 (ja) * | 2005-03-03 | 2006-09-08 | Chisso Corporation | クロロフルオロベンゼン系液晶性化合物、液晶組成物および液晶表示素子 |
BRPI0709209A2 (pt) | 2006-03-28 | 2011-06-28 | Procter & Gamble | processo de redução de hidreto para preparo de intermediários de quinolona |
JP2009531418A (ja) | 2006-03-28 | 2009-09-03 | ザ プロクター アンド ギャンブル カンパニー | キノロン中間体調製のためのカップリング方法 |
US7902227B2 (en) * | 2007-07-27 | 2011-03-08 | Janssen Pharmaceutica Nv. | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents |
CN101298418B (zh) * | 2008-06-13 | 2010-12-15 | 江苏康鹏农化有限公司 | 3-氧代-3-(2,4-二卤代-3-二氟甲氧基苯基)丙酸乙酯的制备方法 |
CN102212056A (zh) * | 2010-04-09 | 2011-10-12 | 山东轩竹医药科技有限公司 | 新的双环喹诺酮类化合物 |
WO2013121439A2 (en) * | 2012-02-15 | 2013-08-22 | Glenmark Generics Limited | Process for garenoxacin mesylate |
KR102237887B1 (ko) | 2013-03-15 | 2021-04-07 | 멜린타 서브시디어리 코프. | 항생제를 사용하여 과체중 및 비만 환자에서 감염을 치료하는 방법 |
GB201516614D0 (en) * | 2015-09-18 | 2015-11-04 | Redx Pharma Plc | Antibacterial compounds |
CN105837555B (zh) * | 2016-03-31 | 2019-01-25 | 南京华威医药科技集团有限公司 | 加雷沙星及其中间体制备方法 |
CN111620901B (zh) * | 2020-06-08 | 2023-03-21 | 蚌埠医学院第二附属医院 | 一种含硅氧烷基的氟喹诺酮化合物、其制备方法及用途 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6199835A (ja) * | 1984-10-22 | 1986-05-17 | Shimadzu Corp | 振動試験機の波形補正装置 |
MY105136A (en) * | 1988-04-27 | 1994-08-30 | Daiichi Seiyaku Co | Optically active pyridonecarboxylic acid derivatives. |
HU219403B (hu) * | 1989-08-16 | 2001-04-28 | Pfizer Inc. | Azabiciklo-csoporttal helyettesített kinolon- és naftiridon-karbonsavak és eljárás ezek előállítására |
EG20543A (en) * | 1992-10-30 | 1999-07-31 | Procter & Gamble | Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones |
JPH07300472A (ja) * | 1992-12-28 | 1995-11-14 | Korea Res Inst Chem Technol | 新規キノロンカルボン酸誘導体およびその製造方法 |
JPH06199835A (ja) * | 1993-01-08 | 1994-07-19 | Hokuriku Seiyaku Co Ltd | 8−ジフルオロメトキシキノリン−3−カルボン酸誘導体 |
DE4301246A1 (de) * | 1993-01-19 | 1994-07-21 | Bayer Ag | Chinolon- und Naphthyridoncarbonsäurederivate |
JPH0848629A (ja) * | 1994-08-08 | 1996-02-20 | Dainippon Pharmaceut Co Ltd | ピリドンカルボン酸誘導体およびそれを有効成分とする抗ピロリ菌剤 |
DE69531350T2 (de) * | 1994-08-12 | 2004-05-27 | Toyama Chemical Co. Ltd. | Neue chinolon- oder naphthyridoncarbonsäurederivate oder deren salze |
-
1997
- 1997-02-07 EP EP97902618A patent/EP0882725B1/en not_active Expired - Lifetime
- 1997-02-07 HU HU9901966A patent/HU228567B1/hu unknown
- 1997-02-07 CN CNB011012323A patent/CN100395244C/zh not_active Expired - Lifetime
- 1997-02-07 AU AU16701/97A patent/AU711914B2/en not_active Expired
- 1997-02-07 CN CN97192130A patent/CN1100053C/zh not_active Expired - Lifetime
- 1997-02-07 IL IL12494497A patent/IL124944A/xx not_active IP Right Cessation
- 1997-02-07 US US09/125,016 patent/US6025370A/en not_active Expired - Lifetime
- 1997-02-07 DE DE69717970T patent/DE69717970T2/de not_active Expired - Lifetime
- 1997-02-07 ES ES97902618T patent/ES2188890T3/es not_active Expired - Lifetime
- 1997-02-07 AT AT97902618T patent/ATE229950T1/de active
- 1997-02-07 CA CA002242242A patent/CA2242242C/en not_active Expired - Lifetime
- 1997-02-07 ZA ZA9701023A patent/ZA971023B/xx unknown
- 1997-02-07 PT PT97902618T patent/PT882725E/pt unknown
- 1997-02-07 NZ NZ330775A patent/NZ330775A/xx not_active IP Right Cessation
- 1997-02-07 WO PCT/JP1997/000317 patent/WO1997029102A1/ja active IP Right Grant
- 1997-02-07 KR KR1019980706138A patent/KR100276477B1/ko not_active IP Right Cessation
- 1997-02-07 DK DK97902618T patent/DK0882725T3/da active
-
1998
- 1998-08-07 NO NO19983625A patent/NO316666B1/no not_active IP Right Cessation
-
2002
- 2002-01-16 HK HK02100336.1A patent/HK1039118B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2242242A1 (en) | 1997-08-14 |
ZA971023B (en) | 1997-09-25 |
IL124944A0 (en) | 1999-01-26 |
HUP9901966A3 (en) | 2002-01-28 |
HK1039118B (zh) | 2009-01-30 |
CN100395244C (zh) | 2008-06-18 |
CN1210533A (zh) | 1999-03-10 |
HUP9901966A2 (hu) | 1999-09-28 |
NO983625D0 (no) | 1998-08-07 |
NZ330775A (en) | 1999-08-30 |
DE69717970T2 (de) | 2003-04-30 |
WO1997029102A1 (fr) | 1997-08-14 |
EP0882725A1 (en) | 1998-12-09 |
NO316666B1 (no) | 2004-03-29 |
HU228567B1 (en) | 2013-04-29 |
NO983625L (no) | 1998-08-07 |
CA2242242C (en) | 2001-08-07 |
IL124944A (en) | 2003-06-24 |
AU1670197A (en) | 1997-08-28 |
PT882725E (pt) | 2003-04-30 |
CN1100053C (zh) | 2003-01-29 |
US6025370A (en) | 2000-02-15 |
AU711914B2 (en) | 1999-10-21 |
EP0882725B1 (en) | 2002-12-18 |
EP0882725A4 (en) | 1999-05-06 |
HK1039118A1 (en) | 2002-04-12 |
KR100276477B1 (ko) | 2000-12-15 |
ATE229950T1 (de) | 2003-01-15 |
KR19990082406A (ko) | 1999-11-25 |
DK0882725T3 (da) | 2003-01-13 |
DE69717970D1 (de) | 2003-01-30 |
CN1314355A (zh) | 2001-09-26 |
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